Comedian Karl Hess (@karlhess) of the podcast Yelling About Pâté and the live show Amuse Bouche returns to the show to talk with Jesse, Matt and Andy about urban legends, ancient Chinese secrets, a possible bit of alien technology that crashed into the ocean, a Cuban lung cancer treatment, Kyle Kinane getting his van stuck in Joshua Tree, the poop-filled beaches of Texas, an extremely shiny exoplanet, and the handful of companies that control the world's beer.

Dan Schreiber of the podcasts No Such Thing as a Fish and The Cryptid Factor, as well as the new book The Theory of Everything Else, joins Matt and Jesse to talk about Nobelitis, using insects to turn beer waste into beef, an ancient slasher dolphin with weird teeth, using shopping cart sensors to identify stroke risk and Keith Alberstadt's bat attack.

On a very special guest-less episode, Matt, Jesse and Andy talk about the fate of the OceanGate Titan, extreme undersea pressure, the curse of the Titanic, whether the Kursk could have been saved, the slightly dubious age-defying claims of a man who lived underwater for several months, the approval of lab-grown meat, Jesse and Andy's latest video game forays, what kangaroos did before they hopped, the problematic platform of RFK Jr. and Matt and Andy's wallaby encounter.

Comedian John Conroy (@ConroyFTW) joins Jesse, Andy and Matt to talk about Grimace's birthday, driving Ronald McDonald around, finding the building blocks of life on Enceladus, federal capital offenses, frog pants, how many people haven't tried ChatGPT and nanotattoos that don't need batteries or wires.

Comedian Anna Valenzuela (@annavisfunny) joins Matt, Jesse and Andy to talk about her myriad jobs including trolley operator and karate instructor, China's space monkey sex plans, why race car drivers blink at the same point on the track and why Michael Caine never blinks at all.

Comedian and comic book author Izzy Salhani (@luckysalhani) joins Jesse, Matt and Andy to talk about bear-baiting, fighting a bunch of kids, a Renaissance fair accident, clay quality, octopus-inpired camouflage ink, Richard Branson's rocket plane taking to the skies again, orcas learning to attack boats and orca fads.

Comedian Liz Miele (@lizmiele) returns to the show to talk about her tour documentary Jet-Lagged, growing up in a veterinarian household, Australian wildlife adventures, a koala chlamydia vaccine, aesthetic scrotal preferences, an Onion classic, Liz's book Why Cats Are Assholes, gymnastics limitations and exceeding astrophysics limitations.

Neuroscientist and clinical psychologist Dr. Heather Berlin (@heather_berlin) joins Matt, Jesse and Andy to talk about hosting the upcoming PBS series Your Brain, the hard problem of consciousness, evolutionary mismatches, panic attack strategies, flow state performance, debating Deepak Chopra about god, the Stanford marshmallow experiment, impulse control, the downside of getting a hangry judge, debunking brain myths, creating consciousness in different substrates, the thermal grill experiment and the fact that we're all going to die.

Comedian and host of the podcasts High and Mighty and ActionBoyz Jon Gabrus (@Gabrus) joins Matt, Jesse and Andy to talk about his hilarious show 101 Places to Party Before You Die, the WGA strike, whether AI can write a 30 Rock scene, the shrinking middle class in entertainment, buffet memories, the benefits of an all-female Mars mission team, curing parrot loneliness with video calls, the insane number of pet birds in the US and advice for a precocious young listener.

Longtime Conan writer and co-creator of Eagleheart Andrew Weinberg joins Andy, Jesse and Matt to talk about his ridiculously funny new show Jury Duty, which follows the workings of a jury trial through the eyes of Ronald Gladden, a juror who is unaware the entire case is fake, the insane hoops they had to jump through to bring the show to life, the truth about weed and creativity, and the unsurprising link between arousal and a desire to have sex with a robot.