Science writer, educator, and artist Dr. Danna Staaf recently published her first book, Squid Empire: The Rise and Fall of the Cephalopods, and she joins Matt and Andy to talk about her dissertation on the reproduction and early life of Humboldt squid, penis fencing among hermaphroditic flatworms, the fact that calamari pre-date the dinosaurs, and why we should all have a lot more respect and awe for cephalopods in general.

Comedian/freestyle rapper Chris Turner (@ChrisPJTurner) joins Andy and Matt to talk about archeology, volcano-based Roman shit, old wine, old Amish people, gay evolution, monkeys playing chicken and the theory of mind. This episode is sponsored by Hello Fresh. For $30 off your first week of HelloFresh, visit hellofresh.com and enter "probably30" at checkout.

Comedian Raj Desai (@_rajdesai) almost makes himself late to his job writing for Sarah Silverman's I Love You, America to do a morning recording with Andy and Matt about his chromatography history, looking more closely at the placebo effect, and how the extinction of dinosaurs made way for mammals to come out during the day.

Comedian Jason Saenz (@jasonsaenz) joins Matt and Andy to talk about Jeff Foxworthy impressions, Saenz Signs, debunked early psychology experiments, oyster hearing, competition-grade oysters, squirrels and lepers, armadillo leprosy in Florida, gold and the documentary series Connections, a good moonbase location, Pluto’s Cave, herbal meds and cancer, blood sweat and Jason's hilarious Comedy Central series Ya Killin' Me.

Comedian Galloway Allbright (@GalloWhy) joins Andy and Matt to discuss the death of expertise, extreme Michael Jackson fandom, that classic Encyclopedia Brittanica ad, the origin of bluegrass, in-flight death plans, channeling your inner Tea Leoni, a neutron star collision, the LIGO song, psilocybin for depression, genes for OCD, Cary Grant’s crazy parental history and LSD, a fundraiser for Dipak's niece, an upcoming Chinese space lab crash, China's NASA and scorpions' toxic blend.

Original co-host Brooks Wheelan (@brookswheelan) and LA PodFest co-founder/The Dollop host Dave Anthony join Matt and Andy for a live Probably Science from the Millenium Biltmore hotel in downtown Los Angeles as part of the 2017 Los Angeles Podcast Festival.

Comedian and host of the Tea With Alice podcast Alice Fraser (@aliterative) joins Matt and Andy to discuss jet lag, breaking the seal, MS, a duck update (duckdate?) with video, a body clock Nobel Prize, Dr. Matt Walker’s new sleep book, a LIGO Nobel Prize and Janna Levin’s book on it, the downside of grass-fed beef, and cargo cults.

Comedian Sharon Houston (@sharon_houston) joins Matt and Andy to discuss flavor profiles, hurricane prep, Hemingway lookalikes, wolverines, duck dicks, finger phone contact, genes vs. alleles, the concept of zero, chisanbop counting, zapping people out of vegetative states, spider sacrifice and more duck dicks.

Comedian Casey Ley (@caseywley) joins Andy and Matt to talk about Andy's car, gay genes, gay face and AI, the first openly gay guy ever, snow leopards becoming less endangered, the end of Cassini, whether or not Saturn would float in water, the first live 4K video from space, the life of Sam Blackman, and Casey's podcast. This episode is brought to you by Hello Fresh. Visit hellofresh.com and use the promo code “probably30” to save $30 off your first week of deliveries.

Comedian and author of Real Artists Have Day Jobs (and three other books) Sara Benincasa (@SaraJBenincasa) invited Matt and Andy into her kitchen to talk about Burning Man, Woodstock '99, talking people down from drugs, creating cryptocurrencies, Space Camp vs. Space Academy, whiskey dilution, faces trained on Skype, Zika for brain tumors, and the secret messages contained in dogs' sneezes.