The gang's back together to celebrate 400 episodes of Probably Science! Erstwhile hosts Jesse Case (@jessecase) and Brooks Wheelan (@brookswheelan) join Matt and Andy to discuss counting magicians, Jesse's proximity to train tracks, Ig Nobel prizes for alligators on helium and narcissist eyebrows, detecting phosphine in the clouds of Venus, finding super old sperm in amber, an earthquake hack to measure ocean warming and podcast recommendations including Our Fake History, Entry Level and Jesse vs. Cancer. This episode is brought to you by The Great Courses Plus, offering Probably Science listeners a free trial with unlimited access by visiting TheGreatCoursesPlus.com/probably

Jesse Case rejoins the show for a cancer special with science writer Dr. Kat Arney (@Kat_Arney), author of Rebel Cell: Cancer, Evolution, and the New Science of Life's Oldest Betrayal. This episode is brought to you by The Great Courses Plus, offering Probably Science listeners a free trial with unlimited access by visiting TheGreatCoursesPlus.com/probably

Comedian Jen Burton (@jensburpin) joins Matt and Andy to discuss Africa getting rid of wild polio, painting turbine blades to save birds, a Jeopardy furry champ, an uncuttable material and Idyllwild's very good boy Mayor Max.

Mia Jackson (@miacomedy) join Matt and Andy to talk about old-time casino heists, asteroids that are the greatest basketball player of all time, ancient Americans, songbirds warming up and 100-million-year-old microbes that are still alive. Check out Mia’s performances on Unprotected Sets on Epix, and her Comedy Central half hour. This episode is brought to you by The Great Courses Plus, offering Probably Science listeners a free trial with unlimited access by visiting TheGreatCoursesPlus.com/probably

Despite a technical glitch, the excellent Adam Cayton-Holland (@CaytonHolland), star of Those Who Can’t, the new podcast The Grawlix Saves The World, and his new album Semblance of Normalcy, talks with Andy and Matt about the word stentorian, Earth’s magnetic anomaly, scientific collaborations and X shapes in the galaxy, finding out there's more than one foot, the threat of swooping magpies and what, exactly, ropey means. This episode is brought to you by The Great Courses Plus, offering Probably Science listeners a free trial with unlimited access by visiting TheGreatCoursesPlus.com/probably

Writer, actress and story coach Lynn Ferguson (@lynnfergy) joins Matt and Andy to talk about house snooping and fountain misuse, chickens, wasps in figs, coyote melons, spying on penguin poop, Andy's hiking discovery, painting eyes on cow butts and whether hot water freezes faster than cold. Check out Michelle Biloon’s album Permanent Hat and Sara Schaefer's book Grand!

Matt’s Last Comic Standing buddy (and Season 5 winner) Jon Reep @jonreep joins Matt and Andy to talk about getting COVID, meteors and moons, Shazam for spiders, anus-escaping water beetles, unusual places to grow a penis, medieval antibiotics, Jon's new podcast Country-ish and this totally independent, unbiased ranking of podcasts that we hope to break. This episode is brought to you by The Great Courses Plus, offering Probably Science listeners a free trial with unlimited access by visiting TheGreatCoursesPlus.com/probably

Improv and comedy acting legend Mike McShane (@thismikemcshane) joins Matt and Andy to talk about the funniest kind of nudity, cognitive impairment tests, the limits of human eating, the star that's hurtling across the universe, a sperm robot story we've done before, and mathematicians boycotting the police. This episode is brought to you by The Great Courses Plus, offering Probably Science listeners a free trial with unlimited access by visiting TheGreatCoursesPlus.com/probably

Comedian Jonah Ray (@jonahray), host of Jonah Raydio and co-guest with Matt on TONIGHT'S episode of The Great Debate on Syfy, talks about his great Seeso show Hidden America, taking over MST3K (and his favorite episode), how flying snakes fly, hungry hungry black holes, Twitter hacks and Bitcoin scams, talking to prairie dogs and the coming population crash. This episode is brought to you by StartAPod, providing our listeners with a special offer by visiting StartAPod.com/probably

Comedian Steph Tolev (@StephTolev) joins Andy and Matt from Toronto to discuss quarantining and TikTok-ing with her family, the history of sled dogs, a black neutron star discovery, putting sheep in K-holes and a $23 million space toilet.