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The Orthogonal Bet

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Feb 15, 2025 • 42min

Dominic Falcao on How Deep Science Ventures Redefines Deep Tech Innovation

In this episode, host Samuel Arbesman speaks with Dominic Falcao, a founding director of Deep Science Ventures (DSV), which he created in 2016 after leading Imperial College London’s science startup program. Deep Science Ventures takes a principled and problem-based approach to founding new deep tech startups. They have even created a PhD program for scientists specifically geared towards helping them create new companies.Sam wanted to speak with Dom to discuss the origins of Deep Science Ventures, as well as how to think about scientific and technological progress more broadly, and even how to conceive new research organizations.Dom and Sam had a chance to discuss tech trees and the combinatorial nature of scientific and technological innovation, non-traditional research organizations, Europe’s tech innovation ecosystem, what scientific amphibians are, and the use of AI in the realm of deep tech.Produced by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Christopher Gates⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Music by Suno
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Feb 15, 2025 • 45min

⁠Max Bennett on A Brief History of Intelligence

In this episode, host Samuel Arbesman speaks with writer, researcher, and entrepreneur⁠ Max Bennett⁠. Max is the cofounder of multiple AI companies and the author of the fascinating book ⁠A Brief History of Intelligence⁠: Evolution, AI, and the Five Breakthroughs That Made Our Brains. This book offers a deeply researched look at the nature of intelligence and how biological history has led to this phenomenon. It explores aspects of evolution, the similarities and differences between AI and human intelligence, many features of neuroscience, and more.Produced by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Christopher Gates⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Music by Suno
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Feb 15, 2025 • 38min

⁠Lev Grossman on The Role of Complexity in World-Building

In this episode, host Samuel Arbesman speaks with novelist ⁠Lev Grossman⁠. A longtime fan of Lev’s novels, the host delves into his works, including ⁠The Magicians trilogy⁠—a splendid set of books about a university for magic, fantastical worlds, and much more. These books are amazing. Lev’s newest book is the novel ⁠The Bright Sword⁠, a retelling of the legends of King Arthur, particularly focusing on what happens after Arthur dies.The Sam devoured The Bright Sword and found it fascinating. It’s a book that weaves together ideas about gods and magic, the layering of myths across history, and much more—all topics explored in the conversation with Lev.Lev and Sam discuss the story of King Arthur, its gaps and its history, the layering of gods and stories over time, the nature of magic and religion, the importance of secondary worlds, and the magic in The Magicians versus the magic of The Bright Sword. They even have a chance to discuss Lev’s next project, which is a space opera. This episode was a lot of fun.Produced by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Christopher Gates⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Music by Suno
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Feb 15, 2025 • 44min

Alex Miller⁠ on The Wonders of Graph Paper and Algorithmic Art

In this episode, host Samuel Arbesman  speaks with⁠ Alex Miller⁠, a software developer and artist known for his work on a project called ⁠Spacefiller⁠. This project exemplifies generative art, where computer code is used to create art and imagery. Spacefiller itself is a pixelated form of artwork that feels organic and biological, but is entirely crafted through algorithms.Sam invited Alex to discuss not only Spacefiller, but also the broader world of generative art, and the concept of coding as a fun and playful activity. Together, they explore topics such as the distinction between computation as art and computation as software engineering, the nature of algorithmic botany, and even the wonders of graph paper.Produced by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Christopher Gates⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Music by Suno
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Feb 15, 2025 • 40min

⁠J. Doyne Farmer on Complexity Economics

In this episode, host Samuel Arbesman speaks with ⁠J. Doyne Farmer⁠, a physicist, complexity scientist, and economist. Doyne is currently the Director of the Complexity Economics program at the Institute for New Economic Thinking at the Oxford Martin School and the Baillie Gifford Professor of Complex Systems Science at the Smith School of Enterprise and the Environment at the University of Oxford.Doyne is also the author of the fascinating new book ⁠“Making Sense of Chaos: A Better Economics for a Better World.”⁠Sam wanted to explore Doyne’s intriguing history in complexity science, his new book, and the broader field of complexity economics. Together, they discuss the nature of simulation, complex systems, the world of finance and prediction, and even the differences between biological complexity and economic complexity. They also touch on Doyne’s experience building a small wearable computer in the 1970s that fit inside a shoe and was designed to beat the game of roulette.Produced by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Christopher Gates⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Music by Suno
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Feb 15, 2025 • 42min

Tarin Ziyaee⁠ on Artificial Life and Robotic Evolution

In this episode, host Samuel Arbesman speaks with ⁠Tarin Ziyaee⁠, a technologist and founder, about the world of artificial life. The field of artificial life explores ways to describe and encapsulate aspects of life within software and computer code. Tarin has extensive experience in machine learning and AI, having worked at Meta and Apple, and is currently building a company in the field of Artificial Life. This new company—which, full disclosure, Sam is also advising—aims to embody aspects of life within software to accelerate evolution and develop robust methods for controlling robotic behavior in the real world.Sam wanted to speak with Tarin to discuss the nature of artificial life, its similarities and differences to more traditional artificial intelligence approaches, the idea of open-endedness, and more. They also had a chance to chat about tool usage and intelligence, large language models versus large action models, and even robots
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Feb 15, 2025 • 36min

Omar Rizwan⁠ on Connecting Online Communities to In-Person Programming

In this conversation, host Samuel Arbesman speaks with ⁠Omar Rizwan⁠, a programmer currently working on ⁠Folk Computer⁠. Omar has a longstanding interest in user interfaces in computing and is now focused on creating physical interfaces that enable computing in a more communal and tangible way—think of moving sheets of paper in the real world and projecting images onto surfaces. Folk Computer is an open-source project that explores a new type of computing in this vein.Samuel engages with Omar on a range of topics, from Folk Computer and the broader space of user interfaces, to the challenges of building computer systems and R&D organizations. Their conversation covers how Omar thinks about code and artificial intelligence, the world of physical computing, and his childhood experiences with programming, including the significance of meeting another programmer in person for the first time.Produced by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Christopher Gates⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Music by Suno
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Feb 15, 2025 • 30min

Eli Altman on The Art of Naming

In this episode, host Samuel Arbesman Sam speaks with ⁠Eli Altman⁠, the managing director of A Hundred Monkeys, a company that specializes in the art of naming. ⁠A Hundred Monkeys⁠ works with clients to come up with the perfect name for a company, product, or anything else that requires a name.The art of naming is a fascinating subject. Throughout human history, the power of names has been a recurring theme in stories and religion. A well-crafted name has the ability to evoke emotions and associations in a profoundly impactful way.Sam invited Eli to the show because he has been immersed in this field for decades, growing up with a father who specialized in naming. The conversation explores the intricacies of this art, how experts balance competing considerations when crafting a name, the different types of names, and what makes a name successful. They also discuss the importance of writing and storytelling in naming, the impact of AI on the field, and much more.Produced by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Christopher Gates⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Music by Suno
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Feb 15, 2025 • 43min

Alex Komoroske on How to Navigate Complexity Within a Large Organizations

In this episode, host Samuel Arbesman Sam speaks with ⁠⁠Alex Komoroske⁠⁠, a master of systems thinking. Alex is the CEO and co-founder of a startup building at the intersection of AI, privacy, and open-endedness. Previously, he served as the Head of Corporate Strategy at Stripe, and before that, spent many years at Google, where he worked on the Chrome web platform, ambient computing strategy, Google Maps, Google Earth, and more.The throughline for Alex is his focus on complex systems, which are everywhere: from the Internet to biology, from the organizations we build to society as a whole. These systems consist of networks of countless interacting parts, whether computers or people. Navigating them requires a new mode of thinking, quite different from the top-down rigid planning many impose on the world.Alex is deeply passionate about systems thinking and its broad implications—from making an impact in the world and navigating within and between organizations to understanding undirectedness and curiosity in one’s work.His more bottom-up, improvisational approach to systems thinking reveals insights on a range of topics, from how to approach large tech companies and the value of startups, to a perspective on artificial intelligence that untangles hype from reality.Produced by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Christopher Gates⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Music by Suno
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Feb 15, 2025 • 43min

Adrian Tchaikovsky⁠ on Bio Trajectories and the Importance of Long-Term Thinking

In this episode, host Samuel Arbesman speaks with ⁠Adrian Tchaikovsky⁠, the celebrated novelist of numerous science fiction and fantasy books, including his Children of Time series, Final Architects series, and The Doors of Eden. Among many other topics, Adrian’s novels often explore evolutionary history, combining “what-if” questions with an expansive view of the possible directions biology can take, with implications for both Earth and alien life. This is particularly evident in The Doors of Eden, which examines alternate potential paths for evolution and intelligence on Earth.Sam was interested in speaking with Adrian to learn how he thinks about evolution, how he builds the worlds in his stories, and how he envisions the far future of human civilization. They discussed a wide range of topics, including short-term versus long-term thinking, terraforming planets versus altering human biology for space, the Fermi Paradox and SETI, the logic of evolution, world-building, and even how advances in AI relate to science fiction depictions of artificial intelligence.Produced by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Christopher Gates⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Music by Suno

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