Dr. Jennifer Wagner is trained as a pediatric anesthesiologist and spent most of her career at Stanford. Then, 2 years ago, she made the decision to shift and leave clinical practice and move to the mountains with her family, and became the Chief Medical Officer at Liminal Collective. Thank you to our sponsors:LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products at InsideTracker.com/AGEIST.Science Research Wellness — improve your cellular health. Listeners receive 20% off all products with code AGEIST20 at SRW.co. Dr. Wagner discusses how she is taking a 40-year preventative approach to her aging, the poor quality of life of a doctor, why she stepped back from that lifestyle, Liminal Collective, how she is teaching women to optimize their lives through her new project “Prosper,” performance, and more. “I used to drive home from Stanford and sit in my garage and cry before I went in to take care of my two kids under 4. I was so stressed from work and then walk in and have to be a mom in a split second after working a 12-hour day.”“The pandemic really took a toll on women, having to balance careers and kids at home, so there was a huge exit of women out of the workplace that still hasn’t recovered.”  “Is everything optimal? Is waiting until I have a significant risk factor, is that really the right time to start prevention? To me, I said no.”“I am super fortunate my parents are still alive but I’ve watched them age and I would prefer to age differently. They’re doing okay but they’re not the way I want to be at 78. That really sparked looking into how I can optimize myself now so that every ten years my risk factors stay zero.” “Keeping people out of the hospital, keeping people healthy, and keeping people off medication is not financially lucrative for a lot of industries which is unfortunate but it’s the bottom line.” “We get so busy. You can spend your entire day from the moment you wake up to the moment you go to bed trying to live a longer life but there also can just be moments of joy, slowing down, looking up. We get in such a hurry all the time but smiling, saying hello to someone on a trail, and appreciating what’s around us has significant health benefits.” Listen to the SuperAge podcast wherever you get your pods.Connect with Dr. Jennifer Wagner:LinkedInLiminal Collectivejen@weprosper.coSay hi to the AGEIST team!

What is the default mode network? How does breathwork impact our thinking? What is the power of acts of kindness? What is the art of living? How do we find our purpose? Thank you to our sponsors: Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist. LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products at InsideTracker.com/AGEIST.Dr. Kien Vuu, concierge performance and longevity physician specializing in human optimization and regenerative medicine, media expert, and author, joins us on the SuperAge podcast to discuss the default mode network, how to live well beyond the science of longevity, finding your purpose, and more. “It’s so important to be aware of the things that trigger us because it might be coming from our past. If we’re not aware of that program that’s running below the surface, we’re going to be making choices from the unconscious conditioned autopilot mode of the brain.” “The energy of love, of healing, of laughter can spread across a community just as fast as fear, resentment, hate, so energy can ripple across.” “How we treat each other, how we treat strangers, that is actually medicine as well and just as powerful.” “How we choose to show up in every single moment of our life is medicine. That’s the art of living.” “We come into this world with this authentic love vibration of just who we are as kids, that’s who we are authentically, so the things that naturally bring joy to us, the things that light us up, the things that make us feel good, those things are programmed in our DNA. Purpose is really just us to exist as us.” Listen to the SuperAge podcast wherever you get your pods.Connect with Dr. Kien Vuu:WebsiteInstagramFacebookLinkedInThrive State Book 2nd EditionSay hi to the AGEIST team!

Should we feel guilty about enjoying life when there is suffering in the world? How does prayer work? How can we be useful to others? Should we enjoy abundance? What is the importance of relationships for our health? How much self-care is appropriate? Thank you to our sponsors: Science Research Wellness — improve your cellular health. Listeners receive 20% off all products with code AGEIST20 at SRW.co. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products at InsideTracker.com/AGEIST.LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. Clayton Crawley, Episcopal priest and EVP, Chief Church Relations Officer at The Church Pension Group joins us to discuss his religious beliefs, how to enjoy life while understanding suffering, how to be useful, longevity, and more. “Part of being a joyful person is to understand that being selfish is actually a path to misery. You can enjoy the best things in life but it’s when you take that enjoyment and hold it tightly, you are committing what in Christianity we would call a sin. You’re being selfish.” “If you give your life away, you will actually save it.” “You can be selfish and have all the money and all the health that you need but you will die because that’s not what it’s about. It is about giving to others, being generous, being joyful. The people that are the most joyful, in my experience, are those who have the most connections.” “What keeps your brain healthy and what makes you happy long-term is having relationships with other people.” “I believe that we are called to live well as long as we live.”“It’s really a gift to be in relationship with other people.” Listen to the SuperAge podcast wherever you get your pods. Connect with Clayton:LinkedInChurch Pension GroupSay hi to the AGEIST team!

What is metabolic health? What is glucose? What is a continuous glucose monitor? How does stress impact our glucose levels and spikes? Why should we eat protein before carbs? How does time of day impact our metabolism? How does caffeine impact glucose levels? Thank you to our sponsors:LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products atInsideTracker.com/AGEIST.Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist. Kara Collier is the co-founder and VP of Health at Nutrisense, one of America’s fastest-growing wellness-tech startups, where she leads the health team. Kara is a Registered Dietitian Nutritionist (RDN), Licensed Dietitian/Nutritionist (LDN), and Certified Nutrition Support Clinician (CNSC) specializing in glucose control and metabolism.Kara joins us to discuss metabolic health, glucose as we age, how stress impacts our glucose spikes, the importance of protein, and more. “Typically what you see in the ICUs actually are complications from lifestyle-related chronic conditions. Something like needing an urgent leg amputation because of uncontrolled diabetes or needing to be put on dialysis because of uncontrolled cardiovascular disease. These were the types of instances I was seeing over and over and that experience led to some frustrations wishing I could help people sooner so they never had to end up there in the first place.” “Just like a car has an engine that interacts with many different components of the car to run it, we have a similar cellular engine and that would be considered metabolic health as a whole.” “It’s not that we never have our glucose move, it’s just that we want to keep it in these  healthy ranges and we don’t want to overload those places where glucose can go.” “If somebody is relatively healthy, their metabolic health looks good overall but their fasted glucose level is always high, typically the #1 thing that’s happening is chronic stress.” “With nutrition specifically, the framework we try to teach people is: master the basics, understand the fundamentals that everyone should be doing and then be malleable and empirical. Be willing to be flexible in your approach based off of your own personalized data because we all are unique.” “About the worst thing that you could do for your glucose levels is a liquid form of sugar.” Listen to the SuperAge podcast wherever you get your pods. Connect with Kara:InstagramLinkedInNutrisenseSay hi to the AGEIST team!

What happens if you outlive your money? What do we need to know about investments? How can we have peace of mind about our finances? What does retirement look like in the future? What is an annuity?Thank you to our sponsors: LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products at InsideTracker.com/AGEIST.Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist. Kate Beattie is a senior retirement income strategist with American Funds and she empowers individuals to understand their finances. She discusses what an annuity is, how to find peace of mind around your finances, how to not outlive your money, and more. “Think of those folks who are approaching retirement and they’ve got that family history of longevity, they’re in excellent health, they’re likely to experience that above average longevity or life expectancy. If they haven’t saved enough to achieve their retirement spending goal but they’re looking to maximize their income, however long that may be, those are excellent candidates for an annuity.” “The connection between peace of mind and secure income or that protected lifetime income was so strong across all investors.” “Our dreams of retiring at 65 might now be 80, in order to make your funds last until 120.” “Write down a list of everybody that you talk to on a weekly basis, now go through and cross out every one of those that are people you work with. Our list gets really small. What is our purpose in that next phase?” Listen to the SuperAge podcast wherever you get your pods. Connect with Kate:LinkedInDisclaimer:  The views depicted in this material are for information purposes only and are not necessarily those of Capital Group/American Funds. The views and commentary should not be considered specific advice or recommendations for any individuals.​​Figures are past results and are not predictive of results in future periods.Investments are not FDIC-insured, nor are they deposits of or guaranteed by a bank or any other entity, so they may lose value. Investors should carefully consider investment objectives, risks, charges and expenses. This and other important information is contained in the fund prospectuses and summary prospectuses, which can be obtained from a financial professional and should be read carefully before investing.  For current information, visit capitalgroup.comSay hi to the AGEIST team!

What is senescence? What about autophagy? What role does caloric restriction play in senescent cells? How does rapamycin impact vaccine efficacy? What do we need to know about fisetin and quercetin? What is the #1 thing that we should avoid to protect our DNA? Thank you to our sponsors:Science Research Wellness — improve your cellular health. Listeners receive 20% off all products with code AGEIST20 at SRW.co. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products atInsideTracker.com/AGEIST.LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. Matt Yousefzadeh, PhD is an instructor and researcher at Columbia University and specializes in aging, cancer, DNA repair, immunology, senescence, and more. He joins us to discuss inflammaging, senescence, the impact of rapamycin on vaccine efficacy, the #1 thing we should avoid to protect our DNA, and more. “We’re losing our ability to respond to new challenges as we progress through time.” “When they gave the elderly a version of rapamycin and then gave them an annual influenza vaccination, they made 20% more antibodies against influenza, and the immune cells or T cells showed reduced markers of exhaustion.” “If you take old mice, the equivalent of an elderly individual, and then put them on fisetin, just supplemented in the chow, it made them live a little bit longer but it also reduced their senescent cell burden and many markers of pathology in their tissues, or improved some of their physiological function.” “As our bodies age, all our tissues are aging at different times and different rates.”“By and large, the things that we can affect in our everyday life are things like diet and exercise. We also know, too, that chronic stress has been shown to shorten life, social stress has been shown to shorten the lifespan of mice. We even see that social stress can have an impact on our immune function.” Listen to the SuperAge podcast wherever you get your pods.Connect with Matt & resources mentioned:Matt's LinkedInAmerican Aging AssociationThe Gerontological Society of America Say hi to the AGEIST team!

What is a 3rd generation vibration wearable and how does it impact stress, focus, recovery, and social interactions? How can we track our stress levels? How is Apollo Neuro different from other wearable technologies? Listeners receive $40 off Apollo Neuro: https://apolloneuroscience.pxf.io/c/3793750/892804/12331Dr. Dave Rabin, MD, PhD, is a neuroscientist, board-certified psychiatrist, health tech entrepreneur & inventor who has been studying the impact of chronic stress in humans for over 15 years. He is the co-founder & chief innovation officer at Apollo Neuroscience, which has developed the first scientifically-validated wearable technology that actively improves sleep, relaxation, focus, and calm, using a novel touch therapy that signals safety to the brain. Dr. Rabin is the executive director of The Board of Medicine & the medical director of the Apollo Clinic.Dr. Rabin joins us to discuss stress, how he is using elements of music and touch as a way to activate the parasympathetic nervous system with his company Apollo Neuro, how Apollo helps sleep, focus, recovery, social interactions, and more.Thank you to our sponsors:LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products at InsideTracker.com/AGEIST.Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist. “Stress is everywhere and it will always be there. The question is how do we look at it from the perspective of growth rather than suffering, and if we can look at it from the perspective of growth then we can actually change the outcome of the situation.” “Touch is free; we can apply it to ourselves, we can apply it to each other. It doesn’t require a lot of skill. It does require a positive intention that is a sharing of kindness, affection, human interaction.” “Holding hands, getting a hug, these kinds of sensations are potently activating the parasympathetic nervous system so they dramatically calm the body. And they can do it within seconds without effort by the person receiving the hug or receiving the hand hold.” “We think about stress as sometimes being positive, helping us grow; and sometimes being negative, and hurting our performance and our recovery. “This is really the first of the gen-3 wearables that are wearables that actually change the body. And it’s the first one to use sound in a scientifically validated way to change the body, change the way we feel, and improve our ability to sleep and focus and recover from stress.” Listen to the SuperAge podcast wherever you get your pods. Say hi to the AGEIST team!

How is Bryan Johnson changing the field of longevity through his health optimization protocol? What is Project Blueprint? What are the self destructive behaviors that have become normalized in society? What are the simple health things that everyone should implement in their life? What are some of the skincare protocols that Bryan incorporates? LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products atInsideTracker.com/AGEIST.Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist. Bryan Johnson is the world's most measured human. Johnson sold his company, Braintree Venmo, to PayPal for $800m in 2013. Since then, he's been investing millions to slow and reverse his aging. In 2021, he set a World Record by reducing his epigenetic age by 5.1 years in 7 months. His program Project Blueprint is an endeavor to help people take better care of themselves. Bryan Johnson discusses how he went from physically unwell to where he is today, aging slower than a 10 year old, his current protocol and Project Blueprint, our normalized destructive behaviors, how he “fired” himself for the sake of his health, his skin health routine, the future of technology, and more. “Wouldn’t it be possible for you and I to have an imagination of ourselves if we said ‘Okay, David, what are you and I in 20 years?’ What if we could assume better instead of inevitable decay? How would that change the way we approach life, work with each other, deal with each other, what effect would it have on humanity?” “Could I build an algorithm that would take better care of me than I could myself and could we attach ourselves to the progress curves of technology and science so that you and I can say ‘What do you and I look like in 20 years? We don’t know, but better.’” “It’s reasonable to think that the things we’re doing like prioritizing sleep, eating vegetables, limiting caloric intake, are things that other humans will do well with.” “How many times in the past week have we eaten too much food, the wrong kind of food, have we not prioritized seep, have we drank too much, smoked, or whatever your vices are, just in the past week. Do an accounting of that and say, what is my load of self destructive behaviors? That to me is the most significant opportunity for improvement.” “I just want an algorithm to take care of my health and wellness, I know my own mind, if I give my own mind the smallest opportunity to make a decision, it’s going to make the wrong decision every single time. I just cannot trust myself, I know this.” “Talent is the ability to hit the target no one else can. Genius is the ability to hit the target no one else can see.”“The difference between hope and despair is a good night’s sleep. When I have a good night’s sleep, everything feels possible. When I have a discouraging night’s sleep, everything feels challenging.” Listen to the SuperAge podcast wherever you get your pods. Connect with Bryan Johnson:Project Blueprint InstagramTwitterLinkedInSay hi to the AGEIST team!

How does exercise improve physical and cognitive health? Is loss of function a normal part of aging? What is proprioception and how does age impact it? What is dual tasking? What is the importance of improving our balance? Learn more about Vivo and receive a free month:  https://momence.com/Vivo/membership/Vivo-Promo-Month-for-Ageist-Members/54570 Science Research Wellness — improve your cellular health. Listeners receive 20% off all products with code AGEIST20 at SRW.co. LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products atInsideTracker.com/AGEIST.Kevin Snodgrass is the head trainer at Vivo and Dr. Joe Nocera is an Associate Professor of Neurology. Kevin and Dr. Nocera join us to discuss how exercise positively affects our physical and cognitive health, how Vivo is treating the brain like any other muscle in the body, what dual tasking is, and more. “Walking is almost automatic until we start to age and then it becomes a little more of a challenge and it becomes a little more variable; and if it’s a little more variable it introduces fall risk.” “We know that we can improve the physical functioning profile of pretty much anybody whether they’re in a disease state or they're aging healthily but we can also really impact brain health with exercise.” “Older adults think of loss of function as a normal part of this process and it really isn’t, it shouldn't be… If we think about loss of function as a normal part of the process, we’re kind of giving up. And what I want to do is show people that we can get back a lot of what we lost.” “We have no way to predict who’s going to fall. Our number one predictor of falls is a previous fall and that doesn’t do anyone any good.”Listen to the SuperAge podcast wherever you get your pods.Say hi to the AGEIST team!

What are peptides? What about semaglutide? Are these safe to take for weight loss? How does aging and menopause impact weight gain? What is the importance of lifestyle changes to improve our health? Learn more about B-Untethered and Telegenixx https://b-untethered.com/rule-midlife-jumpstart/.Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist. LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products at InsideTracker.com/AGEIST.Erin Keyes is the co-founder and CEO of Telegenixx, a company expanding access to personalized regenerative care and peptide- or hormone-based treatment. Anissa Buckley is the founder of B-Untethered, a menopause company integrating science into a results-focused, personalized, specific lifestyle plan just for you. Erin and Anissa join us to discuss peptides, semaglutide, Ozempic, weight gain during the aging process, how we must also address our lifestyle, and more. Erin and Anissa join us to discuss peptides, semaglutide, Ozempic, weight loss during the aging process, how we must also address our lifestyle, and more. Semaglutide itself is a series of amino acids.” “We don’t wake up one day and we’re obese. We slowly but surely throughout the lifespan, through environmental factors, lifestyle factors, genetic factors, etc. can gain weight.” “The average woman over the age of 45, 45% of us are obese; not overweight.” “When you can personalize the care that you’re offering and giving those specific, actionable routes, I do think that it creates this opportunity to carry that forward on their own terms.” “Maybe the Groupon versions of semaglutide are promoting shot only but I would imagine that even they are not. This is a component of a person’s life. It is not the only thing that we hope that they are doing to pursue their own health.”Listen to the SuperAge podcast wherever you get your pods.Say hi to the AGEIST team!