Software People Stories

Should we take aspirin every day? What do we need to know about cholesterol and statins? What level of cholesterol is healthy? What is epigenetics? What is the effect of stress on our epigenetics? What is the effect of stress on our microbiome? How did therapeutic plasma exchange make mice younger and how is this technology being used for humans? Thank you to our sponsor, LMNT — our favorite electrolytes. Listeners receive a free 8-serving sample pack with their purchase here. Thank you to our sponsor, InsideTracker — the dashboard to your Inner Health. Listeners get 20% off on all products here.Dr. Michael Roizen is the Chief Wellness Officer Emeritus at Cleveland Clinic, award-winning author, and founder of RealAge. Dr. Roizen joins us to discuss his new book The Great Age Reboot, how stress impacts our health, what numbers we should aim for for cholesterol, therapeutic plasma exchange, and more. “Stress, it turns out, turns on genes that make proteins that cause inflammation. Moderating stress — that is, happiness — turns off those same genes and turns on genes that make anti-inflammatory proteins — proteins that decrease inflammation.” “The most important things are posse and purpose: having 6 friends you’re vulnerable to every month, having a purpose in life, and a job with latitude.” “When you exercise, you change the genes that are on in your microbiome. When you’re stressed, you change which genes are on in your microbiome.” “I still think you should shoot for cholesterol less than 70 in your blood.” “The most important things you do for brain health are posse and purpose, that’s one. The second one is to add speed to your exercise, that is to stress your muscle; and the third is to add speed to your brain games.” Listen to the SuperAge podcast wherever you get your pods. Connect with Dr. Michael RoizenBuy “The Great Age Reboot: Cracking the Longevity Code for a Younger Tomorrow” TwitterLinkedInSay hi to the AGEIST team!

Why do men struggle with being vulnerable? What are the life expectancy differences between men and women? How can we connect with new people in real life? What is the importance of asking people for help, especially for men? What’s the deal with mansplaining? Thank you to our sponsor, LMNT. Listeners receive a free 8-serving sample pack with their purchase here. Thank you to our sponsor, InsideTracker. Listeners get 20% off on all products here.Greg Scheinman is the creator of The Midlife Male™, a newsletter and podcast designed to help men navigate and maximize middle age to achieve a better quality of life. Greg is a former partner at Insgroup, the founder and former CEO of Team Baby Entertainment, founder and former CEO of ROW Studios, and an investor. Greg joins us to discuss why men tend to struggle with being vulnerable and asking for help, how to get 1% better each day, the importance of reaching out to new people, and more. “How do we flip the midlife crisis on its ear and see that the next phase is our best phase rather than our best days being behind us?” “58% of men in midlife report anxiety, loneliness, frustration, fear of aging, deep regret around the decisions that matter most. And it’s a time period where self-confidence is at an all time low.” “You don’t go from fat to fit overnight. You don’t go from unhealthy to healthy overnight. It’s a series of daily wins and progress.” “Weakness is not asking for help. The weakness is thinking you know everything, that you’ve got to push that boulder up the hill all by yourself. That you’ve got to have all the answers.” “What if instead of viewing aging as something to be afraid of, as something to fear, what if we started to see aging as something aspirational, something inspiring?”“Focus on the small little wins or the 1% better each and every day.” “Don’t just be in motion. Take action.” Listen to the SuperAge podcast wherever you get your pods. Connect with Greg Scheinman:WebsitePodcastInstagramSay hi to the AGEIST team!

What is rapamycin? What is mTor? What is the connection between rapamycin and cancer? How does rapamycin activate autophagy? Who should and shouldn’t take rapamycin? What are the benefits and risks of intermittent fasting? Thank you to our sponsor, LMNT. Listeners receive a free 8-serving sample pack with their purchase here. Thank you to our sponsor, InsideTracker. Listeners get 20% off on all products here. Ross Pelton, pharmacist and scientific director for Essential Formulas, Inc joins us to discuss rapamycin and its potential benefit for age-related diseases, its connection to cancer treatment, intermittent fasting, and more. Disclaimer: This is not medical advice. Always consult your doctor before adding any supplements or medications into your life. “Rapamycin is the most effective anti-aging drug that’s ever been discovered.” “These days, people start eating at 7 in the morning and do breakfast, lunch and dinner and mid-meal snacks and dessert after supper and maybe an evening cocktail. So, from 7 in the morning until 7 at night, that’s 12 hours, another 4 hours to finish digesting food, that’s 16 hours. Whereas ancestral humans only had 4 hours of eating and digesting a day.” “You can’t be in a go, go, go position all the time or you will burn yourself out.”“In animal studies, virtually every single type of age-related disease improves when the animals take rapamycin.” Listen to the SuperAge podcast wherever you get your pods. Connect with Ross Pelton:WebsiteBookArticles (1, 2, 3)Say hi to the AGEIST team!

Dr. Nathan Bryan is an international leader in molecular medicine and nitric oxide biochemistry. Dr. Bryan was the first to describe nitrite and nitrate as indispensable nutrients required for optimal cardiovascular health. He was the first to demonstrate and discover an endocrine function of nitric oxide via the formation of S-nitrosoglutathione and inorganic nitrite.Thank you to our sponsor, LMNT. Listeners receive a free 8-serving sample pack with your purchase here. Thank you to our sponsor, InsideTracker. Listeners get 20% off on all products here. Dr. Bryan joins us on the SuperAge podcast to explain this complex topic. He shares the role nitric oxide plays in inflammation and blood flow, the connection between nitric oxide and our oral microbiome, how to test our nitric oxide levels, what the importance of daily sunlight is, red light therapy, the connection to Raynauds, and more. “Every single chronic disease whether its heart disease, Alzheimer’s, diabetes, liver disease, or lung disease, the common denominator in all of them is decreased blood flow, increased inflammation, and nitric oxide is what controls and regulates both of those things. It decreases inflammation and increases blood flow.” “People who use mouthwash have higher blood pressure than those who don’t and it puts them at an increased risk for heart attack and stroke.” “If you’re using mouthwash, you have to stop. Mouthwash is bad news. There is clear evidence that it increases blood pressure. In fact, if you use mouthwash and exercise, you lose the cardioprotective benefits of exercise.” “Exercise stimulates nitric oxide production and that’s why exercise is medicine.” “Since 1946 – 2018 there’s a 78% decline in all nutrients in plants grown and vegetables grown in the US.”“The foods we eat today, every single American is deficient in one or more nutrients.” “Taking apple cider ginger before every meal is probably the best therapeutic strategy you can do.” “Most Americans with chronic disease are overmedicated. They’re on 6, 8, 10 sometimes 12 different medications and there’s never a discussion of how the physician is going to get you off of those meds. With that many drugs your body cannot heal itself, your body can’t perform.” Listen to the SuperAge podcast wherever you get your pods.Connect with Dr. Nathan Bryan:WebsiteInstagramLinkedInTry Dr. Nathan Bryan’s Nitric Oxide Products. Use code “AGEIST” to save 10%.NO2U, use code “AGEIST” to save 10% and get free shipping.N1O1 Age-Defiance Serum, use code “AGEIST” to save 10% and get free shipping.Say hi to the AGEIST team!

What are the benefits of cold exposure? How did Jono James take control of his health after a terminal diagnosis through practices like cold exposure? Why does the body need stressors like cold and exercise? What types of breathing help during cold exposure? Thank you to our sponsor, InsideTracker. Listeners get 20% off on all products here. Jono James was born with a condition called cystic fibrosis which impacts his lungs, liver, pancreas, and digestive system. He was given 10 years to live when he was born. Now, he is 35 years old and, through a series of natural health methods, including cold therapy, he took control of his diagnosis and beat the odds. Jono created Odin Ice Baths to help others because of the success he has found in doing cold therapy.  Cold therapy has been beneficial in David’s life by helping him recover from workouts faster, preventing injury, reducing pain, enhancing mental and cognitive function, improving sleep, and more. Always check with your doctor to make sure that your body can handle cold exposure, and to what degree. “I’m 35 now and I was given 10 years to live when I was born, more or less. Most people look at me and don’t think there’s anything wrong with me. That comes down to me trying everything… I’ve treated myself like a one-person clinical trial and I’ve tried things over and over again and, eventually, I found a select few things that really, really help me.” “There are so many people with anxiety and depression these days and most people seem to find that they get a lot of benefit from the ice baths.”“It’s a positive stress on the body. It’s a stress that challenges the body to get better.”“When you exercise, the body goes, ‘Oh, I’m not actually good enough how I am now. You’re putting me under a bit of pressure; I need to build muscle mass and become better and stronger.’ ” “The body is not designed to sit around on a comfy couch. It’s supposed to be challenged, it’s supposed to be a tool for foraging and hunting. The more we separate ourselves from the way we used to do things the less good our health becomes.” “In an ideal world, I’d do sauna every day.” Listen to the SuperAge podcast wherever you get your pods.  Connect with Jono:WebsiteOdin Ice BathsSay hi to the AGEIST team!

How can we test our gut microbiome and what can we do with the results? What is our oral microbiome? How is Viome revolutionizing cancer and disease detection, prevention, and elimination? What is Dr. Momo’s vision for the future of health?Dr. Momo Vuyisich is the Co-founder, Chief Science Officer, and Head of Clinical Research at Viome Life Sciences whose mission is to digitize, decode, and decipher human biology for the prevention, early diagnosis, and treatment of chronic diseases and cancer. AGEIST founder David Stewart is a testimony of Viome’s ability to help us reach optimal health. Dr. Momo explains the science behind Viome’s technology, the individualized approach to Viome’s treatment plans, how they are revolutionalizing the detection of oral & throat cancer, the importance of our oral microbiome, Dr. Momo’s vision for the next 10 years, and more. SuperAge listeners receive $30 off Viome’s Health Intelligence Test here. Use code “AGEIST”. “No matter what condition you are looking at, you should look at the whole body and not just the isolated organ. “The process of digestion starts in the mouth, there are enzymes that are released in the mouth and there are both microbial and human enzymes.” “I wanted to create a technology that is advanced and molecular and super hard to do but be accessible to everyone in the world just like the app store.” “We are focusing on preventative and curative strategies and not these maintenance strategies where you’re given medication for the rest of your life and you still are deteriorating or you’re still not getting better.” “Symptoms are the terminal stages of a disease. Molecular disease happens years oor decades before the symptoms are felt. If you want to know your status that you are heading for a heart attack, you can know that 30 years before the heart attack.” Listen to the SuperAge podcast wherever you get your pods. Connect with Dr. Momo:LinkedInViome Life Sciences Say hi to the AGEIST team!

Is our mind our brain? How does meditation help us inspect our minds? What is the connection between anxiety and meditation? What is the connection between our mind and addiction? How can we measure our wellbeing? Thank you to our sponsor, Viome. SuperAge listeners get $30 off Viome’s Health Intelligence Test with code “AGEIST” here. Richard J. Davidson, PhD is a Professor of Psychology and Psychiatry, Founder and Director of the Center for Healthy Minds, University of Wisconsin-Madison, and the Founder and Chief Visionary for Healthy Minds Innovations, Inc. Dr. Davidson explores what our minds are, how types of meditation help us inspect our minds, his relationship with His Holiness the 14th Dalai Lama, how we can measure wellbeing, and more. “Beliefs about ourselves, the world, and our expectations literally shape our experience in the world.” “I often say that meditation is like sports. There are many, many, many varieties and they each will have differing effects.” “Thinking is what human minds and brains do. We’re very well equipped to think. The goal of meditation is not to stop thinking, the goal is to stop getting lost.” “We can’t transform our mind unless we know what our minds are actually doing.” “When you begin to actually open up the black box of our mind, begin to inspect it and interrogate it, it could be terrifying to see what’s there because it’s so chaotic for many people.” “One of the things that distinguish humans from other species is that we have the capacity to engage in mental time travel. We can reflect on the past and we can anticipate the future.” “Human beings are born to flourish. We have all of the capabilities to lead a happy, meaningful, and engaged life. We come into the world with those capacities but they need to be nourished in order for them to be expressed.” Listen to the SuperAge podcast wherever you get your pods. Connect with Dr. Richard Davidson: WebsiteBooksHealthy Minds Program AppCenter for Healthy Minds InstagramSay hi to the AGEIST team!

Dr. Cliff Olson is an Audiologist, founder of Applied Hearing Solutions in Phoenix, Arizona, and former Marine. Dr. Olson has devoted his entire career to treating individuals with hearing loss to get them their communication back and potentially stave off the negative consequence of cognitive decline. Dr. Olson shares everything we need to know about hearing loss from the different kinds, the connection between hearing loss and cognitive decline, how to approach hearing aids, and more. Thank you to our sponsor, LMNT. SuperAge listeners receive a free 8-serving sample pack with your purchase here. Thank you to our sponsor, InsideTracker. SuperAge listeners get 20% off all products here.What are the different types of hearing loss? How can we prevent and treat hearing loss? What is the difference between an audiologist, ENT, otologist? What is the impact of today’s earbuds and headphones? What is the connection between hearing loss and cognitive decline? What are cochlear implants? What is tinnitus? “Hearing loss really is a silent epidemic because once you start losing your hearing you don’t really know what you’re missing. “The funny thing about the human brain is that your brain will reorganize the way that it processes information if you’re missing access to speech information.” “If you’re someone who is 65 years old and you have not had an actual, legitimate baseline hearing test by an audiologist, you need to find an audiologist in your area and schedule a baseline test whether you think you have hearing loss or not.” “It only takes as little as 3 months with mild level hearing loss for your brain to start changing the way that it processes information.” “If you have mild level hearing loss you are 2x more likely to develop dementia. If you have moderate hearing loss you are 3x more likely and if you have severe hearing loss you are 5x more likely to develop dementia.” “Hearing loss is the leading potentially modifiable risk factor for dementia later in life and it accounts for 9% of your overall risk of developing dementia.” Listen to the SuperAge podcast wherever you get your pods. Connect with Dr. Cliff OlsonWebsiteYouTube FacebookLinkedIn Say hi to the AGEIST team!

What are the stages of perimenopause, menopause and post-menopause? How does a woman’s body change during menopause? What role does diet play? How much protein, carbohydrates, and fat should women eat? What is the benefit of HIIT and strength training for women? How does a woman’s metabolism change in menopause? Thank you to our sponsor, Viome. SuperAge listeners get $30 off Viome’s Health Intelligence Test with code “AGEIST” here. Thank you to our sponsor, LMNT. SuperAge listeners receive a free 8-serving sample pack with your purchase here. Anissa Buckley is a champion of life. She holds an MBA and a BS from Cornell University, an Integrative Health Coaching certification from Duke Integrative Medicine, a holistic nutrition counseling certification (CHHC) from The Institute for Integrative Nutrition, and a personal training certification (CPT) from The National Academy of Sports Medicine. Now, she is the founder and CEO of b-untethered, a personalized menopause diet and fitness lifestyle solution. Anissa shares her journey of being rocked by the physical and emotional changes that perimenopause and menopause brought, how she took agency over her own health during and post menopause, and her mission to help other women do the same. “When I was 45, I was in perimenopause which is really the most critical time for a woman because that’s when a lot of things can happen to your hormones. Your estrogen levels can just start rollercoastering and your progesterone, which balances out or offsets estrogen, can stay flat and you can imagine that that can really cause havoc.” “I really wanted to understand what we could do as women with our lifestyle — not medications, but more about how we could change our lifestyle to help us mitigate some of these impacts that we see.”“When women hit menopause, they lose the ability to utilize carbs the same way.”“Lifestyle can control for about 80% of chronic conditions. The CDC says that. That’s not just you and me making up statistics.” “It’s not necessarily an easy thing to make a life shift but it’s baby steps. You don’t have to be perfect on day 1. You just have to start making some changes and you’ll start to feel better and then you’ll want to make more changes. It’s that simple."Listen to the SuperAge podcast wherever you get your pods. Connect with Anissa:b-untethered websiteb-untethered FacebookAnissa's LinkedInLook out for Anissa’s book Midlife: Turning Crisis Into Quest coming out in October.Say hi to the AGEIST team!

What is functional neurology and who can benefit from it? Can functional neurology make you smarter? What does Dr. Hardy test for to determine the health of the brain? What is the relationship between moving and thinking? How can you address age-related cognitive decline with functional neurology? What is the process of cognitive decline? How does posture connect to the brain? Dr. David Hardy, functional neurologist, uses several techniques that specifically stimulate neuronal receptors, nerves, pathways, and circuits to improve an individual's own neuroplasticity. Through his work, he enhances his patient's brains and nervous systems. He shares what functional neurology is, how it can be used to enhance performance, brain health, and more. Thank you to our sponsor, LMNT. SuperAge listeners receive a free 8 serving sample pack with your  purchase here. Thank you to our sponsor, InsideTracker. SuperAge listeners get 20% off all products here. “We’ve got all these weak or strong areas of our brain that we can hone in on and make changes and make improvements to improve our lives, performance, and how smart we are.” “The thing with cognition especially as we age is we became really good at one aspect. So we can appear smart because we’re always rehearsed but the rest of the ship might be starting to leak and eventually it’s going to lead to a decline in our cognitive thoughts as well.” “Our nervous system is there to regulate our own body against the outside world and to move around, read, and react.” “If you’re in the stress posture, what are your head and neck like? They're going forward and you have all this tension through those muscles. All of that is sending signals up to the brain and then that signal fires into our feelings center and then we are annoyed, sore, stiff, and will probably snap at people a lot easier.” “Anything new is going to stimulate the brain in a more impactful way. This is also a way to measure decline as we age. How able are we to actually learn new tasks?” Listen to the SuperAge podcast wherever you get your pods. Connect with Dr. David Hardy: InstagramWebsiteFacebookLinkedInSay hi to the AGEIST team!