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What happens if you outlive your money? What do we need to know about investments? How can we have peace of mind about our finances? What does retirement look like in the future? What is an annuity?Thank you to our sponsors: LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products at InsideTracker.com/AGEIST.Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist. Kate Beattie is a senior retirement income strategist with American Funds and she empowers individuals to understand their finances. She discusses what an annuity is, how to find peace of mind around your finances, how to not outlive your money, and more. “Think of those folks who are approaching retirement and they’ve got that family history of longevity, they’re in excellent health, they’re likely to experience that above average longevity or life expectancy. If they haven’t saved enough to achieve their retirement spending goal but they’re looking to maximize their income, however long that may be, those are excellent candidates for an annuity.” “The connection between peace of mind and secure income or that protected lifetime income was so strong across all investors.” “Our dreams of retiring at 65 might now be 80, in order to make your funds last until 120.” “Write down a list of everybody that you talk to on a weekly basis, now go through and cross out every one of those that are people you work with. Our list gets really small. What is our purpose in that next phase?” Listen to the SuperAge podcast wherever you get your pods. Connect with Kate:LinkedInDisclaimer:  The views depicted in this material are for information purposes only and are not necessarily those of Capital Group/American Funds. The views and commentary should not be considered specific advice or recommendations for any individuals.​​Figures are past results and are not predictive of results in future periods.Investments are not FDIC-insured, nor are they deposits of or guaranteed by a bank or any other entity, so they may lose value. Investors should carefully consider investment objectives, risks, charges and expenses. This and other important information is contained in the fund prospectuses and summary prospectuses, which can be obtained from a financial professional and should be read carefully before investing.  For current information, visit capitalgroup.comSay hi to the AGEIST team!

What is senescence? What about autophagy? What role does caloric restriction play in senescent cells? How does rapamycin impact vaccine efficacy? What do we need to know about fisetin and quercetin? What is the #1 thing that we should avoid to protect our DNA? Thank you to our sponsors:Science Research Wellness — improve your cellular health. Listeners receive 20% off all products with code AGEIST20 at SRW.co. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products atInsideTracker.com/AGEIST.LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. Matt Yousefzadeh, PhD is an instructor and researcher at Columbia University and specializes in aging, cancer, DNA repair, immunology, senescence, and more. He joins us to discuss inflammaging, senescence, the impact of rapamycin on vaccine efficacy, the #1 thing we should avoid to protect our DNA, and more. “We’re losing our ability to respond to new challenges as we progress through time.” “When they gave the elderly a version of rapamycin and then gave them an annual influenza vaccination, they made 20% more antibodies against influenza, and the immune cells or T cells showed reduced markers of exhaustion.” “If you take old mice, the equivalent of an elderly individual, and then put them on fisetin, just supplemented in the chow, it made them live a little bit longer but it also reduced their senescent cell burden and many markers of pathology in their tissues, or improved some of their physiological function.” “As our bodies age, all our tissues are aging at different times and different rates.”“By and large, the things that we can affect in our everyday life are things like diet and exercise. We also know, too, that chronic stress has been shown to shorten life, social stress has been shown to shorten the lifespan of mice. We even see that social stress can have an impact on our immune function.” Listen to the SuperAge podcast wherever you get your pods.Connect with Matt & resources mentioned:Matt's LinkedInAmerican Aging AssociationThe Gerontological Society of America Say hi to the AGEIST team!

What is a 3rd generation vibration wearable and how does it impact stress, focus, recovery, and social interactions? How can we track our stress levels? How is Apollo Neuro different from other wearable technologies? Listeners receive $40 off Apollo Neuro: https://apolloneuroscience.pxf.io/c/3793750/892804/12331Dr. Dave Rabin, MD, PhD, is a neuroscientist, board-certified psychiatrist, health tech entrepreneur & inventor who has been studying the impact of chronic stress in humans for over 15 years. He is the co-founder & chief innovation officer at Apollo Neuroscience, which has developed the first scientifically-validated wearable technology that actively improves sleep, relaxation, focus, and calm, using a novel touch therapy that signals safety to the brain. Dr. Rabin is the executive director of The Board of Medicine & the medical director of the Apollo Clinic.Dr. Rabin joins us to discuss stress, how he is using elements of music and touch as a way to activate the parasympathetic nervous system with his company Apollo Neuro, how Apollo helps sleep, focus, recovery, social interactions, and more.Thank you to our sponsors:LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products at InsideTracker.com/AGEIST.Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist. “Stress is everywhere and it will always be there. The question is how do we look at it from the perspective of growth rather than suffering, and if we can look at it from the perspective of growth then we can actually change the outcome of the situation.” “Touch is free; we can apply it to ourselves, we can apply it to each other. It doesn’t require a lot of skill. It does require a positive intention that is a sharing of kindness, affection, human interaction.” “Holding hands, getting a hug, these kinds of sensations are potently activating the parasympathetic nervous system so they dramatically calm the body. And they can do it within seconds without effort by the person receiving the hug or receiving the hand hold.” “We think about stress as sometimes being positive, helping us grow; and sometimes being negative, and hurting our performance and our recovery. “This is really the first of the gen-3 wearables that are wearables that actually change the body. And it’s the first one to use sound in a scientifically validated way to change the body, change the way we feel, and improve our ability to sleep and focus and recover from stress.” Listen to the SuperAge podcast wherever you get your pods. Say hi to the AGEIST team!

How is Bryan Johnson changing the field of longevity through his health optimization protocol? What is Project Blueprint? What are the self destructive behaviors that have become normalized in society? What are the simple health things that everyone should implement in their life? What are some of the skincare protocols that Bryan incorporates? LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products atInsideTracker.com/AGEIST.Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist. Bryan Johnson is the world's most measured human. Johnson sold his company, Braintree Venmo, to PayPal for $800m in 2013. Since then, he's been investing millions to slow and reverse his aging. In 2021, he set a World Record by reducing his epigenetic age by 5.1 years in 7 months. His program Project Blueprint is an endeavor to help people take better care of themselves. Bryan Johnson discusses how he went from physically unwell to where he is today, aging slower than a 10 year old, his current protocol and Project Blueprint, our normalized destructive behaviors, how he “fired” himself for the sake of his health, his skin health routine, the future of technology, and more. “Wouldn’t it be possible for you and I to have an imagination of ourselves if we said ‘Okay, David, what are you and I in 20 years?’ What if we could assume better instead of inevitable decay? How would that change the way we approach life, work with each other, deal with each other, what effect would it have on humanity?” “Could I build an algorithm that would take better care of me than I could myself and could we attach ourselves to the progress curves of technology and science so that you and I can say ‘What do you and I look like in 20 years? We don’t know, but better.’” “I just want an algorithm to take care of my health and wellness, I know my own mind, if I give my own mind the smallest opportunity to make a decision, it’s going to make the wrong decision every single time. I just cannot trust myself, I know this.” Listen to the SuperAge podcast wherever you get your pods. Connect with Bryan Johnson:Project Blueprint InstagramTwitterLinkedInSay hi to the AGEIST team!

How does exercise improve physical and cognitive health? Is loss of function a normal part of aging? What is proprioception and how does age impact it? What is dual tasking? What is the importance of improving our balance? Learn more about Vivo and receive a free month:  https://momence.com/Vivo/membership/Vivo-Promo-Month-for-Ageist-Members/54570 Science Research Wellness — improve your cellular health. Listeners receive 20% off all products with code AGEIST20 at SRW.co. LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products atInsideTracker.com/AGEIST.Kevin Snodgrass is the head trainer at Vivo and Dr. Joe Nocera is an Associate Professor of Neurology. Kevin and Dr. Nocera join us to discuss how exercise positively affects our physical and cognitive health, how Vivo is treating the brain like any other muscle in the body, what dual tasking is, and more. “Walking is almost automatic until we start to age and then it becomes a little more of a challenge and it becomes a little more variable; and if it’s a little more variable it introduces fall risk.” “We know that we can improve the physical functioning profile of pretty much anybody whether they’re in a disease state or they're aging healthily but we can also really impact brain health with exercise.” “Older adults think of loss of function as a normal part of this process and it really isn’t, it shouldn't be… If we think about loss of function as a normal part of the process, we’re kind of giving up. And what I want to do is show people that we can get back a lot of what we lost.” “We have no way to predict who’s going to fall. Our number one predictor of falls is a previous fall and that doesn’t do anyone any good.”Listen to the SuperAge podcast wherever you get your pods.Say hi to the AGEIST team!

What are peptides? What about semaglutide? Are these safe to take for weight loss? How does aging and menopause impact weight gain? What is the importance of lifestyle changes to improve our health? Learn more about B-Untethered and Telegenixx https://b-untethered.com/rule-midlife-jumpstart/.Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist. LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products at InsideTracker.com/AGEIST.Erin Keyes is the co-founder and CEO of Telegenixx, a company expanding access to personalized regenerative care and peptide- or hormone-based treatment. Anissa Buckley is the founder of B-Untethered, a menopause company integrating science into a results-focused, personalized, specific lifestyle plan just for you. Erin and Anissa join us to discuss peptides, semaglutide, Ozempic, weight gain during the aging process, how we must also address our lifestyle, and more. Erin and Anissa join us to discuss peptides, semaglutide, Ozempic, weight loss during the aging process, how we must also address our lifestyle, and more. Semaglutide itself is a series of amino acids.” “We don’t wake up one day and we’re obese. We slowly but surely throughout the lifespan, through environmental factors, lifestyle factors, genetic factors, etc. can gain weight.” “The average woman over the age of 45, 45% of us are obese; not overweight.” “When you can personalize the care that you’re offering and giving those specific, actionable routes, I do think that it creates this opportunity to carry that forward on their own terms.” “Maybe the Groupon versions of semaglutide are promoting shot only but I would imagine that even they are not. This is a component of a person’s life. It is not the only thing that we hope that they are doing to pursue their own health.”Listen to the SuperAge podcast wherever you get your pods.Say hi to the AGEIST team!

What is the connection between HRT and breast cancer? How long can someone safely be on HRT? What does Dr. Suzanne make of the recent menopause movement? Why do we need to keep an open mind when it comes to medical advances? What is Dr. Suzanne seeing in the menopause and aging field that is interesting to her? Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist. LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 10% off on all products atInsideTracker.com/AGEIST.Dr. Suzanne Gilberg-Lenz is a doctor, expert, speaker, and advocate for integrative women's health. She has also created a Menopause Bootcamp to de-stigmatize the aging process and help empower women. Dr. Suzanne discusses HRT for menopause, what we need to know about hormones and breast cancer, how the medical field is everchanging and we must keep an open mind, what is interesting her in the menopause and aging field, and more. “This is not a disease; this is a state of being alive. So you have options in terms of how you want to live and age well, whatever that means to you.” “Science is not a religion. It is not a monolith, it is not unchanging and unmoving. That is not what science is. Science is a process of inquiry. Period. End of sentence.”“There’s actually quite a bit of data on the potential health benefits of estrogen specifically in all of us and in breast cancer survivors.” “The vast majority of us who are diagnosed with breast cancer are going to be diagnosed at early stages. The vast majority of those of us diagnosed with breast cancer are going to die of: breast cancer or heart disease? Heart disease!” “The number one tool for healthy aging is lifestyle. That’s always the best. Exercise, movement, getting the blood flowing, staying flexible, mindset – it’s really not rocket science.”“One of the great things as we age, if we have community, we have support, we have tools, is we start to settle more into who we are and start to appreciate that.” Listen to the SuperAge podcast wherever you get your pods. Connect with Dr. Suzanne Gilberg-Lenz:WebsiteInstagramTwitterFacebookLinkedInYouTubeSay hi to the AGEIST team!

What does the future hold for us as a society? What about age? When are we getting the flying cars that we were promised? How will life stages change in the future? How are things like ChatGPT changing our world? What is a brand in the future? Faith Popcorn, futurist and best-selling author, is renowned for her extraordinary ability to position brands and entire corporations to succeed in the ever-evolving landscape of Tomorrow, with an accuracy rate of over 95% in forecasting everything from technology to nutrition to personal care. Faith joins us to discuss what the future looks like for society, age, life stages, entertainment, work, and more. Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist. LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 20% off on all products at InsideTracker.com/AGEIST.“I think that age – in the future, the issue will be: How can I live healthily into the future? But also, we haven’t answered some of the questions like: Are you going to still stay married to the same person for 130 years? Unlikely, I think. Are you going to still have the same occupation? Will you have your dream occupation? Will you run out of money?”“Entertainment is going to be very, very important. I know it’s adorable that we go to a movie theater but we can probably watch something that’s on a lens in our eye. We’re going to be able to go to the Metaverse with a lens that’s in our eye.” “There may be time travel before we have a flying car. We may be able to move our molecules through space before we have a flying car. It’s much more efficient.” “If somebody else can do it as well as you can do it, let them do it… And then you can either make it a little better, make it a little different, or do something else that they can’t do.” Listen to the SuperAge podcast wherever you get your pods. Connect with Faith Popcorn:WebsiteInstagramFacebookSay hi to the AGEIST team!

What are the economic implications of living longer? Why do we need to change the way we are aging? How long will we need to work because of our increased life expectancy? What will retirement look like in the future? What assets should we be investing in? InsideTracker — the dashboard to your Inner Health. Listeners get 20% off on all products atInsideTracker.com/AGEIST.Science Research Wellness — improve your cellular health. Listeners receive 20% off all products with code AGEIST20 at SRW.co. Andrew J. Scott is a Professor of Economics at London Business School having previously held positions at Oxford University, London School of Economics and Harvard University. His work focuses on the economics of longevity and he is the co-author of The 100-Year Life and The New Long Life.Andrew joins us to discuss the economic implications of living longer, how we need to change the way we are aging, what retirement will look like in the future, the assets that we should be investing in, and more. “What we need to do is to change how we age. We need to age better. Rather than focusing on, ‘Oh, there are more old people,’ I think we need to focus on, actually, given the phenomenal increase in life expectancy that has happened, we need to change how we age.”“We haven’t really expected to reach into those older ages in the past. Of course, there have always been old people but it’s been a minority living to 80 or 90. But if you look at the data today in most rich countries, it’s the majority who will be living to 80 or 90. So, we need to age better and behave differently.” “You’ve got more time ahead of you. Whether you’re 20, 50, or 80, you have more time ahead of you than past 20-year-olds, 50-year-olds, or 80-year-olds. So you have to invest more into your future. You just have a greater incentive to do it.” “The challenge you’ve got with a longer life is how to finance it.”Listen to the SuperAge podcast wherever you get your pods. Connect with Andrew Scott:WebsiteLinkedInBooks: The 100-Year Life & The New Long LifeSay hi to the AGEIST team!

What is therapeutic plasma exchange (TPE)? How does TPE impact brain health? How does inflammation drive aging? What is cell senescence? Are people who donate blood healthier? How frequently does someone need to do TPE? What are the risks? Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist.LMNT Electrolytes — our favorite electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. InsideTracker — the dashboard to your Inner Health. Listeners get 20% off on all products at InsideTracker.com/AGEIST.Dr. Sanjeev Goel, physician and founder of Peak Human, is passionate ​about taking a holistic approach to wellness through Integrative and Regenerative Medicine. He advocates a healthy lifestyle centered around plant-based diet, focused physical activity, and enhancing mental resilience. Dr. Goel joins us to discuss therapeutic plasma exchange, regenerative medicine, longevity, and more. “There’s something about young blood that potentially causes rejuvenation or there’s something about the removal of old blood that actually causes rejuvenation.” “We know that Alzheimer’s is really caused by inflammation and lack of ability to detoxify the brain… so that’s causing more and more inflammation.” “In animals, we have pretty good science that this is causing less neuroinflammation, in muscles it looks like there’s going to be more stem cells, more regeneration in the liver.”“Inflammation seems to be a key driver of aging.” “If you change the base at which these cells are living in and bring it back down to a more youthful stage, then those cells behave like they’re younger.”Listen to the SuperAge podcast wherever you get your pods. Connect with Dr. Sanjeev Goel:LinkedInPeak Human WebsiteEmail: drgoel@peakhuman.ca Say hi to the AGEIST team!