Belcampo: Use the code CARNIVOREMD for 20% off your order!    Ancestral Supplements https://ancestralsupplements.com/ Code SALADINOMD on the shopify site to receive 10% off.   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   JOOVV: www.joovv.com/paul INSIDER: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com

This was a fun, but technical episode.    Cyrus Khambatta has a PhD in nutritional biochemistry from UC Berkeley. Robby Barbaro has a master’s degree in public health. Both have type 1 diabetes and have been featured in plant-based documentaries like Forks Over Knives.    Though Robby and Cyrus have been able to improve their blood sugar control with a fruit heavy plant-based diet, I had some concerns about their approach (inadequate protein, nutrient deficiencies, etc..) so I invited them on the show. Even with almost two hours we didn’t have time to get into everything but we did talk about the biochemical basis of insulin resistance vs glucose sparing in detail and addressed the false notion that low carbohydrate diets cause pathological insulin resistance head on.    I hope you all enjoy this episode and I look forward to doing more animal vs plant “debates” with plant based advocates in the future. I don’t want my podcast to be an echo-chamber!  Time Stamps: 8:54 Start of the Podcast  10:01 Cyrus and Robby's story. 16:11 Have either done a low carb ketogenic style diet ? 28:16 Glucose and mean amplitude glucose excursions.  33:26 Paleolithic ketogenic diet and type 1 diabetes(a case study). 39:50 Is there long term studies on the carnivore diet? 44:10 Insulin resistance  54:00 Insulin resistance and hyperinsulinemia  59:31 Are low carbohydrate diets effective in combatting insulin resistance? 1:06:47 LDL cholesterol and cardiovascular disease. 1:18:20 Can blood glucose sensitivity improve on a high carb plant based diet? 1:19:46 Blue Zones  1:27:54 Does saturated fat cause insulin resistance? 1:36:30 Do Cyrus and Robby take any supplements? 1:40:54 Leucine and MTOR. 1:44:30 Why Paul went on the carnivore diet/dissenting opinions on nutrition. 1:54:54 The most radical thing Cyrus and Robby have done recently. Where to find them online. Belcampo: Use the code CARNIVOREMD for 20% off your order!    Ancestral Supplements https://ancestralsupplements.com/ Code SALADINOMD on the shopify site to receive 10% off.   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   JOOVV: www.joovv.com/paul INSIDER: carnivoremd.com   My contact information:  

Dr. Terry Wahls is an Institute for Functional Medicine Certified Practitioner and a clinical professor of medicine at the University of Iowa where she conducts clinical trials.  In 2018 she was awarded the Institute for Functional Medicine’s Linus Pauling Award for her contributions in research, clinical care and patient advocacy. She is also a patient with secondary progressive multiple sclerosis, which confined her to a tilt-recline wheelchair for four years. Dr. Wahls restored her health using a diet and lifestyle program she designed specifically for her brain and now pedals her bike to work each day. She is the author of The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles, Learn more about her MS clinical trials by reaching out to her team: MSDietStudy@healthcare.uiowa.edu. Pick up a copies of her research papers at https://terrywahls.com/researchpapers/ and a one-page handout for the Wahls™ Diet at https://terrywahls.com/diet/   Time Stamps 11:10 Start of the Podcast  12:25 Terry talks about the microbiome and healthy poop. 15:00 Is fibre required for a healthy microbiome? What makes a healthy microbiome? 17:10 Markers looked for in a healthy microbiome. 21:50 Data sets and developing a processed food index. 26:30 Can a lab test determine a healthy microbiome? 27:50 Terry's story. 34:20 Are autoimmune diseases treatable? Chronic inflammation and autoimmunity  36:20 Autoimmunity and plant based diets. 38:30 Autoimmune Paleo and what Terry changed to get better. 46:10 Can you have too much Vitamin A(retinol)? 47:10 Rotterdam study and vitamin k. 50:35 Food quality. 56:00 Terry's diet. 59:10 Thallium in Kale, plant toxins and antinutrients in leafy greens. 1:00:10 Terry's ancestral health perspective on diet. 1:02:25 Paul's perspective. 1:11:30 Blue Zones  1:17:10 Why nutrition should be taught in medical school. 1:23:10 Diet and lifestyle quality and fertility. 1:24:35 Terry's other concerns about a carnivore diet.  1:25:20 Do plants have a benefit in our diet? 1:28:20 Ketosis. 1:33:10 The potential for a carnivore diet controlled clinical trial. 1:34:10 Where to find Terry online. 1:35:00 The most radical thing Terry has done recently. Where to f

Chris Kresser, M.S., L.Ac., is the creator of the ADAPT Practitioner and Health Coach Training Programs. He is one of the most respected clinicians and educators in the fields of Functional Medicine and ancestral health and has trained over 1,300 health professionals around the world in his unique approach. Co-director of the California Center for Functional Medicine, creator of ChrisKresser.com, and New York Times best-selling author, Chris is a prolific communicator; his newest book is Unconventional Medicine. Chris was nominated “Best Inspirational Voice” and “Best Health & Wellness Website” by Paleo magazine 2019. Named one of the 100 most influential people in health and fitness by Greatist.com, he has appeared as a featured guest on The Dr. Oz Show and Fox & Friends, as well as in other national media outlets. Chris lives in Berkeley, CA, with his wife and daughter. Time Stamps:  10:02 Start of the podcast 10:27 Chris' journey. 12:47 What was the result of Chris' rehabilitation?  16:42 How do we heal the gut? 20:17 How to help your parasympathetic nervous system. 24:52 Chris talks about different diets. 26:52 Can you thrive on a vegan diet?(27:27-28:02) 31:02 Chris' opinion of a vegan diet. 36:32 Chris' opinion of animal based diets. 41:17 Paul responds. 48:02 Sustainability of a carnivore diet. 49:52 An exoneration of animal foods and the spectrum of plant toxins. 51:12 Chris' thoughts on plant toxins. 55:02 Vitamin C deficiency on a carnivore diet. 47:12 Fibre and the microbiome. 1:11:32 Where to find Chris. 1:12:12 The most radical thing Chris has done recently. Belcampo: Use the code CARNIVOREMD for 10% off your order!    Ancestral Supplements https://ancestralsupplements.com/ Code SALADINOMD on the shopify site to receive 10% off.   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   JOOVV: www.joovv.com/paul INSIDER: carnivoremd.com   My contact information:  

Ivor Cummins BE(Chem) CEng MIEI PMP completed a Biochemical Engineering degree in 1990. He has since spent over 25 years in corporate technical leadership and management positions. His career specialty has been leading large worldwide teams in complex problem-solving activity.  Since 2012 Ivor has been intensively researching the root causes of modern chronic disease. A particular focus has been on cardiovascular disease, diabetes and obesity. He shares his research insights at public speaking engagements around the world, revealing the key nutritional and lifestyle interventions which will deliver excellent health and personal productivity. He has recently presented on heart disease primary root causes at the British Association of Cardiovascular Prevention and Rehabilitation (BACPR). He has also debated Irish Professors of Medicine on stage, at the annual conference of the Irish National Institute of Preventative Cardiology (NIPC).   Ivor’s 2018 book “Eat Rich, Live Long” (co-authored with preventative medicine expert Jeffry Gerber MD, FAAFP), details the conclusions of their shared research: https://www.amazon.com/Eat-Rich-Live-Long-Mastering/dp/1628602732/   His public lectures and interviews are available on YouTube, where he has 60,000 subscribers and 5 million views have been recorded to date:  https://www.youtube.com/channel/UCPn4FsiQP15nudug9FDhluA.      Most of Ivor’s material is readily accessible via his rapidly growing website:  https://thefatemperor.com/   Ivor is currently the Chief Program Officer and for Irish Heart Disease Awareness: http://www.IHDA.ie   Ivor lives in Dublin, Ireland, with his wife and five children. Time Stamps: 13:19 Start of the Podcast  14:24 Ivor's background in cholesterol research. 18:14 Lab work/lipid panels. 21:04 Triglyceride/HDL ratio. 22:58 hsCRP and fasting insulin. 24:49 Ivor's ferritin levels. 25:12 Ivor's dietary changes. 29:34 Hypertension as criteria for metabolic syndrome.  32:23 How did Ivor's ferritin change ? 34:19 Iron overload on the carnivore diet. 39:19 LDL. 50:09 If LDL was enough to initiate atherosclerosis why do we not see atherosclerosis in veins? 51:59.Artery wall damage. 1:00::29 Glycocalyx. 1:03::48 Oxidized LDL. 1:05::29 Saturated fat and oxidized LDL. 1:08::19 APOE4 and insulin

Dr. James DiNicolantonio, is a Doctor of Pharmacy and a cardiovascular research scientist. A well-respected and internationally known scientist and an expert on health and nutrition, he has contributed extensively to health policy and has testified in front of the Canadian Senate regarding the harms of added sugars. He serves as the associate editor of the British Medical Journal’s Open Heart, a journal published in partnership with the British Cardiovascular Society, and is on the editorial advisory boards of several other medical journals. Dr. DiNicolantonio is the author or coauthor of over 250 publications in the medical literature. He also is the author of three bestselling health books, The Salt Fix, Superfuel and The Longevity Solution. You can follow him on Instagram and Twitter @drjamesdinic and on Facebook at Dr. James DiNicolantonio. You can visit his website at drjamesdinic.com.   Time stamps:   10:25 Electrolytes. How much salt did we have evolutionary ?  13:05 How much salt do humans need? 16:00 Can we go too high on salt consumption? 21:20 Magnesium. 24:45 Insulin Resistance and sodium  27:45 Kidney function. Bumps in BUN and Creatinine. 29:00 How to measure for magnesium deficiency. 31:00 Vitamin C 39:15 Ideal vitamin C intake for humans. 59:45 Concerns of higher vitamin C intake. 1:02::25 Vitamin C and people with G6PD deficiency. 1:07::05 Cadmium and kidneys. 1:11:27 Chlorella and pollutant binding. 1:13:15 Fiber and dioxins. 1:16:35 James' diet. Is it cheaper to eat plant foods? 1:19:35 Molecular xenohormesis. 1:24:30 Are plants beneficial ? 1:32:30 The fear of glucose spikes. 1:34:35 Resistant starch. 1:39:14 Where to find James and the most radical thing he's done recently. Ancestral Supplements https://ancestralsupplements.com/   Code SALADINOMD on the shopify site to receive 10% off.   Use the code CARNIVOREMD at www.whiteoakpastures.com all month for 10% off your order!   JOOVV: www.joovv.com/paul INSIDER: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON:

James W. Clement is a lawyer and entrepreneur turned research scientist who has devoted the last two decades to understanding the science of life extension. He is best known for his Supercentenarian Research Study, which he started in 2010 with Professor George M. Church of Harvard Medical School and has received international press coverage. Through worldwide scientific collaborations and in his own laboratory, James focuses on advancing cutting-edge biomedical discoveries. He is the founder of the nonprofit Betterhumans biomedical research organization. Led by a collection of high-profile researchers, the organization focuses on bringing cutting edge scientific discoveries from the lab to the clinic. Clement was the 12th person in the world to have his whole genome sequenced and is Personal Genome Project participant #145   Time Stamps: 10:10 Start of podcast  10:50 What type of research is James doing and how does it relate to aging? 12:55 Compression of morbidity.  23:50 Feedlot meat and processed foods (23:50-24:35) 25:50 Super centenarian studies. 28:25 Observations on what super centenarians have in common. 31:40 Laron Dwarfs and IGF1 (22:00-22:45) 33:30 Should we over stimulate IGF1? 37:10 Measuring IGF1 39:40 Blue Zones and centenarian diets 42:50 Intermittent Hypoxia  46:40 Over fasting, finding a good balance. 51:40 Environmental hormesis  52:50 Okinawans  55:40 Confounding variables. 1:00:25 mTor/ketosis and glycogen depletion in the liver.  1:03:40 Animal based diets and intermittent ketosis. 1:06:10 James' thoughts on the carnivore diet. 1:10:55 Lack of nutrients in a plant based diet. 1:12:30 Benefits of prolonged ketosis in morbidly obese. 1:16:10 Protein sparing modified fast benefits. 1:20:10 Calorie restricted pure vegan diet. 1:22:00 Dexa scan. 1:25:50 James's insulin levels. 1:27:40 AGEs (advanced glycation end products) 1:34:10 Stress and glucose levels. 1:38:50 Does too much protein harm the kidneys? 1:45:10 Protein cycling. 1:46:34 Occasional long term fasting benefits. 1:47:35 Loma Linda sperm quality. 1:49:40 Carnivore diet for longevity. 1:52:20 Issues with studies comparing meat eaters vs. non meat eaters. 1:54:00 The most radical thing James has done rece

Dr. Gabrielle Lyon discusses protein's role in cancer risk, emphasizing its benefits for muscle health. The podcast delves into mTOR activation, debunking misconceptions about protein intake and cancer. It explores ketogenic diets, brain health, and personal experiences from Navy Seals to medical school.

Dr Jaime Seeman is a board certified Obstetrician and Gynecologist practicing in Omaha, Nebraska. Born and raised in the state she played collegiate softball for the Cornhuskers. She has a Bachelor of Science degree in Nutrition, Exercise and Health Sciences. She then went on to graduate from medical school and completed her OBGYN residency at The University of Nebraska Medical Center. She currently is in private practice at Mid City OBGYN offering a full range of services in obstetrics, gynecology, robotic surgery and primary care. She is a fellow in Integrative Medicine at The University of Arizona School of Medicine. She is a board certified ketogenic nutrition specialist through The American Nutrition Association. She has a passion for fitness, preventative medicine and ketogenic therapy not only in her medical practice but in her own life. She is married to her husband Ben, a police Sergeant and has three young daughters.  Time Stamps: 6:59 Start of the Podcast 7:44 Jaime's story  11:44 Athletes and nutrition  13:24 When did Jamie become insulin resistant/low carb pushback? 18:49 Jamie's vegan/carnivore experiments and postprandial glucose.  20:29 Blood Sugars on carnivore/keto/vegan. 27:59 Was Jaime eating junk food before going keto? 31:33 What is Jaime eating ? 33:14 Hormones on a ketogenic/carnivore diet(women). 46:59 Estrogen dominance  54:29 Methylation. 57:14 If healthy do we need DIM supplements? 1:01:19 What causes high beta glucuronidase? 1:02:59 Thyroid. Do we need carbs for a healthy thyroid? 1:13:29 Postprandial rise in insulin when you eat protein. 1:19:34 How to fix estrogen dominance. 1:23:14 Troubleshooting for hormones  1:31:19 Is low carb safe during pregnancy? 1:42:59 Where to find Jamie.  1:43:44 The most radical thing Jaime has done recently. Dr. Seeman’s contact information:   www.doctorfitandfabulous.com Instagram: @doctorfitandfabulous Ancestral Supplements https://ancestralsupplements.com/   Code SALADINOMD on the shopify site to receive 10% off.   Use the code CARNIVOREMD at www.whiteoakpastures.com all month for 10% off your order!   JOOVV: www.joovv.com/paul INSIDER:

Dr. Will Cole, leading functional-medicine expert, consults people around the world via webcam and locally in Pittsburgh. He specializes in clinically investigating underlying factors of chronic disease and customizing health programs for thyroid issues, autoimmune conditions, hormonal dysfunctions, digestive disorders, and brain problems. Dr. Cole was named one of the top 50 functional-medicine and integrative doctors in the nation and is a health expert and course instructor for the world’s largest wellness brands such as mindbodygreen and goop.   Dr. Cole’s contact information:    www.drwillcole.com Instagram: @drwillcole Ancestral Supplements https://ancestralsupplements.com/   Code SALADINOMD on the shopify site to receive 10% off.   Use the code CARNIVOREMD at www.whiteoakpastures.com all month for 10% off your order!   JOOVV: www.joovv.com/paul INSIDER: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com