Faces of Digital Health

Ali Parsa is a serial entrepreneur known for founding companies that challenge traditional models of healthcare delivery. Over two decades, he has built organizations at the intersection of healthcare, technology, and systems redesign—each shaped by an ambition to make care more efficient, accessible, and equitable. In this episode, Tjasa Zajc and Ali Parsa explore how agentic AI is redefining healthcare and what it really takes to build transformative companies in a fast-shifting world.Ali dives into why healthcare remains stuck in an economic imbalance—unlimited demand but constrained clinical supply—and why autonomous, real-time AI agents may finally rebalance the system by taking over 20–30% of routine clinical tasks. He explains how Quadrivia builds agents that can talk to patients, follow multi-step workflows, and operate within strict guardrails to avoid hallucinations and workflow drift.But this episode goes far beyond technology. Ali opens up about entrepreneurship:• why speed is the only real advantage startups have,• how to hire “missionaries, not mercenaries,”• why products must be excellent from day one,• how processes must be simplified and rebuilt for speed,• and why losing control—even briefly—can cost a company everything. 04:00 The Quest for Differentiation in Healthcare 09:21 AI Agents: Revolutionizing Clinical Tasks 12:42 Building a Reliable Knowledge Base 15:17 Ensuring Workflow Integrity in AI 19:46 Global Expansion Strategy of Quadrivia 22:58 Navigating Trust and Cultural Differences 26:04 Competing with Giants in the AI Space 30:22 Agility in Decision Making 31:15 Lessons from Babylon's Legacy 33:08 The Importance of Speed in Entrepreneurship 35:59 Navigating Failure and Success 39:44 Optimizing People, Product, and Processes 41:25 The Role of Luck in Entrepreneurship 47:14 The Birth of Quadrivia 49:04 Insights from Global Healthcare Markets www.facesofdigitalhealth.com http://fodh.substack.com/

In this episode of Faces of Digital Health, we sit down with Anne Forsyth, Hospital leader in clinical applications from Women's College Hospital in Canada, to explore how AI — especially generative AI — is reshaping daily clinical practice. Over the past two years, enthusiasm for AI has skyrocketed inside hospitals, with clinicians themselves requesting new tools rather than resisting them. We discuss the cautious but deliberate rollout of AI scribes, the still-emerging trust in decision-support AI, and the safety and change-management considerations that mirror (and sometimes exceed) traditional IT implementations. Anne offers an honest look at the financial challenges of sustaining AI tools in publicly funded health systems and shares practical advice for hospitals navigating funding models, clinical buy-in, and responsible innovation. Show notes: 01:50 – Current AI Implementations 03:21 – Safety and Risk Considerations 04:00 – Comparing AI Rollouts to Traditional IT Tools 05:10 – The Business Equation: Funding AI in Public Healthcare 06:20 – Advice for Hospitals on Sustainable AI Adoption 06:40 – Looking Ahead: The Future of AI in Clinical Applications www.facesofdigitalhealth.com https://fodh.substack.com/

In this Faces of Digital Health episode Dr. David Dodick, Chief Science and Medical Officer at the Atria Health Institute and Co-Chair of the Atria Research Institute talks about brain health, dementia prevention, the rapidly evolving science of Alzheimer’s, and how digital tools and AI are transforming care. We also cover why women face higher Alzheimer’s risk, the microvasculature’s role in cognition, and the biggest leap in migraine treatment: CGRP-targeting therapies. A must-watch if you’re curious about prevention, personalized risk, and which consumer tech is actually useful today. Dr. David Dodick trained at the Mayo Clinic and served on the faculty there for more than three decades. At the Mayo Clinic, he founded the Neurology Residency Program, the Headache Fellowship Program, the Sports Neurology and Concussion Program, the Migraine and Headache Program, and co-founded the Vascular Neurology/Stroke Program. What you’ll learn: 1. How much dementia is realistically preventable—and how to lower your risk 2. Why amyloid ≠ destiny, and what “biological vs. clinical” Alzheimer’s means 3. The role of sleep, hearing, blood pressure, metabolic health, and social connection 4. Smart wearables that matter (AFib, BP, CGM) and what’s just hype 5. How AI “diagnostic orchestrators” could supercharge clinicians and empower patients 6. Migraine red flags (when to go to the ER) and the CGRP revolution in treatment

Stephen Ryu, a neurosurgeon and key figure in the Stanford Neuroprosthetics Lab joins Tjaša Zajc on Faces of Digital Health to demystify brain–computer interfaces (BCIs): how they work, why invasive systems outperform non-invasive ones, realistic use cases (motor control and speech), timelines and durability, safety and MRI trade-offs, cybersecurity, business models, and what Paradromics is building as a high-bandwidth BCI platform. Throughout, Stephen separates science fact from sci-fi, stressing near-term potential to restore communication and movement for people living with paralysis, while noting earlier-stage areas like mental health and pain. What we cover: - Invasive vs. non-invasive BCIs, and why electrode proximity to neurons matters for performance - Decoding motor intent and speech: training, language considerations, and LLM-enabled synthesis - Safety, surgery, and durability (why 10-year implant lifespans are a meaningful target) - MRI/CT compatibility trade-offs (and parallels to pacemakers/DBS) - Cybersecurity realities (what BCIs can not do today) - Business models, regulation, and reimbursement paths for medical-grade BCIs - Paradromics’ differentiation: a high-bandwidth platform designed to scale across use cases - Future indications: pain, sensory restoration; earlier stage: mental health biomarkers - The human impact: restoring connection for people who can’t move or speak Chapters: 01:37 How BCIs work; signals, decoding, invasive vs. non-invasive 07:13 Surgery basics, risks, and why proximity boosts performance 09:36 Decoding speech & language considerations 13:31 What’s most advanced today: motor + speech 14:58 Mental health: biomarkers and why it’s early 17:48 Longevity, MRI/CT limits, realistic replacement intervals 21:16 Patient perception: fear, performance, and value vs. alternatives 25:04 Paradromics’ platform & high-bandwidth approach 29:22 Platform use cases by brain area (motor, auditory, etc.) 31:18 Cybersecurity: risks today vs. sci-fi 32:35 Business models, regulation, and access 36:42 Trials landscape; Paradromics’ timeline 37:53 Biggest concerns: hype vs. reality 39:50 Three things everyone should know about BCIs 42:10 Potential in pain management 44:41 Role of AI/ML in decoding and assistive apps 46:36 Final thoughts www.facesofdigitalhealth.com Newsletter: https://fodh.substack.com/

Mazin Gadir, a regional expert in digital health strategy, Director with Alvarez & Marsal Healthcare and Life Sciences in Dubai, reflects on the Middle East’s evolution from early EMR adoption to AI-driven healthcare. From Dubai’s innovation playground to Abu Dhabi’s depth in research, he explains how rivalry between Gulf states fuels progress and why exporting tested models to Africa and beyond is the new norm. He also questions the myth of leapfrogging, pointing out that fragmentation and lack of research remain barriers. This candid conversation explores regulation, interoperability, and the role of academia in sustaining innovation. www.facesofdigitalhealth.com Newsletter: https://fodh.substack.com/ 00:00 – Introduction: blockchain hype and digital health evolution 01:00 – From EMRs to health information exchanges in the Middle East 03:00 – The impact of COVID-19 on digital transformation 04:30 – Rise of patient empowerment and consumerization of healthcare 05:30 – The missing role of academia and research in the region 07:00 – Comparing Abu Dhabi and Dubai’s different innovation models 09:00 – Dubai as a playground for testing, Abu Dhabi for research depth 10:30 – Rivalry across GCC states as a driver of innovation 12:00 – Exporting Gulf digital health models to Africa and beyond 14:00 – Challenges of scaling across Middle Eastern countries 16:00 – Interoperability: current maturity and pilgrim use cases 18:00 – Opportunities and limits of leapfrogging 20:00 – The role of academia and sustainability of innovation www.facesofdigitalhealth.com https://fodh.substack.com/

In this interview, healthcare futurist Reenita Das, Partner at Frost&Sulivan, Healthcare Changemaker, voted top 100 women in Healthtech and Femtech, reflects on the balance between rapid digital health innovation and the human side of care. Speaking from WHX Tech in Dubai, she highlights why empathy, kindness, and caregiving remain essential despite the rise of AI. She also shares insights on the UAE healthcare system—its sophistication, inequities for migrant workers, and opportunities in mental health and digital innovation. Drawing from her experience in 10+ healthcare systems worldwide, Reenita compares global approaches and emphasizes food and lifestyle as drivers of health outcomes. 00:00 – Introduction and reflections on WHX Tech conference 01:00 – Why the human side of healthcare is more important than ever 02:30 – Risks of AI reducing clinician-patient time 03:30 – What AI can and cannot do in healthcare 05:00 – UAE healthcare system: sophistication and inequities 06:30 – Migrant workers and challenges of access to care 07:00 – Comparing healthcare systems across the US, Japan, and India 08:30 – Food and lifestyle as drivers of health outcomes 09:30 – Digital health opportunities in the UAE (mental health, diagnostics, aggregation) 10:30 – Misconceptions about women, culture, and technology in the UAE 11:30 – Advice for startups entering the region www.facesofdigitalhealth.com https://fodh.substack.com/

Dr. Sam Shah is a clinician, advisor, and former startup founder. At WHX Tech he sat down with Tjasa Zajc to discuss the future of dentistry, oral health, and broader digital health innovation. He explains why dentistry has lagged behind other specialties, how oral health connects to overall wellbeing, and why the UAE stands out as “the most digitally connected place on the planet.” Sam highlights government-backed sandboxes, integration engines, and lessons other countries can learn from the Emirates—while also pointing to persistent challenges in standards, interoperability, and prevention. Show notes: 00:00 – Introduction and Sam’s journey from dentistry to digital health 01:00 – Innovations in dentistry: apps, smart toothbrushes, imaging AI 02:00 – Why dentistry lags behind in digital adoption 03:00 – Oral health and its impact on overall health and wellbeing 04:00 – The social determinants of oral health 05:00 – Career across multiple domains: public health, startups, law, economics 06:00 – Why global solutions can’t simply be “lifted and shifted” 07:30 – What makes the UAE stand out: digital connectivity and government support 08:30 – Key government initiatives: Malaffi and Dubai Sandbox 10:00 – Cooperation between federal and emirate levels 11:00 – Lessons for other countries: leadership that listens 12:00 – Areas for improvement: standards, interoperability, prevention 13:00 – Longevity, wellness, and the need for value-based care

At WHX Tech, cybersecurity expert Dr Leila Taghizade, Group Head of Cyber Risk Management / CISO IberoLatAm at Allianz, breaks down what every individual—and every hospital—should know about protecting themselves in 2025. From the basics of stronger passwords and two-factor authentication to the risks of free apps and third-party tools, she explains in clear terms why “there’s no such thing as free lunch” in cybersecurity. Leila also highlights the dangers of phishing, the vulnerability of medical devices, and how AI both helps defenders and lowers the cost of attacks. Show Notes 00:00 – Introduction: why cybersecurity basics matter in 2025 00:30 – Strong passwords, two-factor authentication, limiting app permissions 02:00 – Giving apps only the access they really need 03:00 – Cybersecurity in healthcare: medical devices as weak links 04:30 – Default passwords and firmware updates as major risks 05:30 – Phishing: why reporting is critical for protection 07:00 – Everyday cyber hygiene: logging out, password managers 08:30 – AI’s impact on cybersecurity: lowering cost of attacks, improving defense 10:00 – The risks of free apps and third-party tools 11:00 – Data leaks and how AI tools may unintentionally share information 12:30 – AI as a double-edged sword: prevention vs. risk 14:00 – Final advice: caution doesn’t mean fear, but informed use www.facesofdigitalhealth.com Newsletter: https://fodh.substack.com/

Did you know that  the lifetime prevalence for experiencing a sexual problem is above 70% for women and 55% for men? And when we talk about the problem in conjunction with the distress, it's 25% in women and around 20% in men. So one in four women has the problem right now they are silently suffering because of various issues - challenges discussing issues with their doctor, inadequate awareness among physicians and more. In this episode of Faces of Digital Health, we dive into a topic often overlooked in healthcare: women’s sexual health and sexual distress. Clinical psychologist and sex therapist from Charite, Berlin Selina Marie Kronthaler discusses the prevalence of sexual dysfunction, why sexual distress is still underdiagnosed, and the impact on relationships and quality of life. We explore how digital health tools and evidence-based interventions are being developed to support women in navigating sexual pain, arousal disorders, and emotional challenges in a private, accessible way. The conversation highlights the gaps in current healthcare training, the role of gynecologists, and why femtech innovation and funding are critical to addressing an underserved area that affects 1 in 4 women. E-Mail: selina.kronthaler@charite.de Instagram: https://www.instagram.com/selina.kronthaler/  (German Therapy Website: https://www.selinakronthaler.de/)  www.facesofdigitalhealth.com Newsletter: https://fodh.substack.com/

In this thought-provoking conversation, surgeon Shafi Ahmed and digital health futurist John Nosta revisit Geoffrey Hinton’s bold 2016 prediction that radiologists would soon be replaced by AI. 🔍 Topics covered: Why AI hasn’t replaced radiologists yet—and what’s holding it back The role of large language models in diagnostics and clinical practice The debate over accuracy, intuition, and the “art” of medicine Accountability and liability when AI makes mistakes in healthcare The deeper question: is AI truly intelligent, or does it think in a way fundamentally different from humans? 💡 Shafi and John don’t always agree—but together they explore the future of medicine, the limits of technology, and the ethical, clinical, and philosophical challenges that will define healthcare in the AI era. 02:02 Introduction and Debate Overview 02:17 AI in Radiology: Predictions vs. Reality 04:00 Challenges in AI Implementation 06:32 Generative AI in Clinical Practice 08:50 Ethical and Regulatory Concerns 10:19 Philosophical Perspectives on AI 16:39 Accountability in AI-Driven Healthcare 19:57 AI's Cognitive Differences and Impact on Healthcare 21:30 Conclusion and Final Thoughts www.facesofdigitalhealth.com Newsletter: https://fodh.substack.com/