

AI and Healthcare
xCures
AI and Healthcare—with Mika Newton and Dr. Sanjay Juneja is an engaging interview series featuring world-renowned leaders shaping the intersection of artificial intelligence and medicine. Discover how AI is transforming healthcare today, addressing real-world challenges and improving patient outcomes.
This series caters to anyone’s listening style with bite-sized, commute-friendly insights and full-length interviews. Join co-hosts Mika Newton, CEO of xCures, and Dr. Sanjay Juneja, a globally recognized oncologist and VP of Clinical AI at Tempus AI, as they explore cutting-edge innovations with industry pioneers.
Originally launched as the TARGET: Cancer Podcast in 2021, the series evolved after 75 episodes into a comprehensive platform for AI and healthcare conversations.
This series caters to anyone’s listening style with bite-sized, commute-friendly insights and full-length interviews. Join co-hosts Mika Newton, CEO of xCures, and Dr. Sanjay Juneja, a globally recognized oncologist and VP of Clinical AI at Tempus AI, as they explore cutting-edge innovations with industry pioneers.
Originally launched as the TARGET: Cancer Podcast in 2021, the series evolved after 75 episodes into a comprehensive platform for AI and healthcare conversations.
Episodes
Mentioned books

May 27, 2025 • 3min
How can doctors get the most value out of AI today? - with Dr. Sanjay Juneja
Healthcare is shifting fast. If you’re not actively learning how to use AI, you're already behind. This discussion reveals how to get the most value out of AI in clinical care, even if you're just starting. Host Dr. Sanjay Juneja (https://sjunejamd.com) sits down with physician-entrepreneur Dr. Harvey Castro (https://www.linkedin.com/in/harveycastromd/) to unpack the critical steps healthcare professionals can take right now to stay relevant and lead with AI. They discuss how to build your AI fluency, what content to follow, how to vet sources, and why a passion for patient care should drive your tech adoption. This is essential viewing for clinical leaders, health IT teams, diagnostics innovators, and telehealth executives ready to make informed decisions in a data-driven world.

May 22, 2025 • 49min
How Can AI Make Breast-Conserving Surgery Smarter? - with Dr. Sanjay Juneja [FULL INTERVIEW]
AI-assisted imaging is enhancing the precision of breast-conserving surgery by enabling surgeons to reduce re-excisions, preserve healthy tissue, and make more informed intraoperative decisions. Learn how real-time AI models trained on high-resolution optical coherence tomography (OCT) images are transforming how clean margins are assessed during lumpectomies. Adrian Mendes, CEO of Perimeter Medical Imaging, joins Dr. Sanjay Juneja, The OncDoc, to unpack the technological, clinical, and operational implications of using AI to support breast cancer surgery. They cover practical use cases, data strategy, FDA pathways, and cost-savings that matter to hospitals, payers, and diagnostic partners. If you're a provider, technologist, or decision-maker looking to scale smarter surgical care, listen now for valuable insight into what’s next in surgical AI.

May 21, 2025 • 9min
How can AI address the healthcare worker shortage? - with Dr. Sanjay Juneja
Dr. Harvey Castro, a physician with an MBA and healthcare advisor for Singapore, joins Dr. Sanjay Juneja to discuss how AI can alleviate the healthcare worker shortage. They explore how robotic support can reduce strain on nurses and tools like ambient scribing can ease administrative burdens. The conversation highlights real-world applications of AI in diagnostics and home-based monitoring, emphasizing a future where healthcare professionals connect more with patients and less with paperwork. Ethical considerations and improving patient care through continuous understanding are also key topics.

May 20, 2025 • 7min
Learn how Agentic AI Reshapes Clinical Workflows - with Dr. Sanjay Juneja
Explore how agentic AI is revolutionizing clinical workflows with digital twins of healthcare professionals. This technology enhances decision-making, reduces bottlenecks, and broadens access to expertise across various healthcare settings. Insights into its integration with wearables show the potential for improved emergency care and quicker lab result analysis. The shift towards scalable AI agents promises to boost operational efficiency while maintaining the essential human touch in patient care.

May 16, 2025 • 8min
Should Hospital Systems Build or Buy AI Tools? - with Dr. Sanjay Juneja
Healthcare systems face a critical question: build custom AI tools tailored to their workflows, or buy ready-made solutions? This video unpacks the operational, financial, and clinical factors that inform that decision, including insights on cost, customization, integration, and innovation in patient-centered AI. Dr. Sanjay Juneja (https://sjunejamd.com/) interviews Dr. Harvey Castro (https://www.linkedin.com/in/harveycastromd/) to explore the nuances of AI adoption in hospital systems. They break down the value of federated learning, ambient scribe technologies, cultural considerations in care, and how to ensure AI models support rather than replace clinical decision-making. If you're in health system leadership, clinical informatics, operations, or product strategy, this discussion offers frameworks to guide smarter, sustainable AI investments.

May 15, 2025 • 41min
Digital Twins and the Future of Patient Care - with Dr. Sanjay Juneja [FULL PODCAST]
AI agents are changing how clinical decisions are made, workflows are optimized, and care is delivered across hospitals, labs, and telehealth systems. Learn how these tools can scale medical expertise, streamline bottlenecks, and improve patient outcomes—without replacing the human element. Hosted by Dr. Sanjay Juneja and featuring expert insights from Dr. Harvey Castro, this interview explains how digital twins, ambient AI, and agentic systems can support clinical judgment, reduce burnout, and personalize care at scale. You’ll also hear practical guidance on whether to build or buy AI tools, how to structure healthcare-specific data, and what integration actually looks like in high-pressure environments. If you’re in healthcare leadership, IT, operations, or product development, this discussion provides frameworks and real-world examples you can act on now.

May 14, 2025 • 2min
How is AI Influencing Rare Disease Treatments? [David Fajgenbaum] - with Dr. Sanjay Juneja
AI is reshaping rare disease treatments by accelerating drug repurposing, identifying therapeutic opportunities, and unlocking actionable insights hidden in clinical data. Discover how innovative frameworks and technology platforms are helping healthcare leaders, diagnostic companies, and telehealth providers uncover new treatment pathways faster and more efficiently. Dr. Sanjay Juneja (https://sjunejamd.com/) speaks with Dr. David Fajgenbaum (https://www.linkedin.com/in/davidfajgenbaum) about the ethical imperative of using AI-driven drug repurposing to address underserved rare conditions and the growing potential to surface overlooked therapies. Gain practical insights on decision-making, data analysis, and scalable solutions that can impact patient care.

May 12, 2025 • 3min
How does an open source drug discovery platform empower clinicians? - with Dr. Sanjay Juneja
Unlock faster, smarter drug repurposing with open-source data that arms clinicians and researchers with actionable insights. This discussion explores how cutting-edge AI and knowledge graphs are transforming access to potential therapies by ranking 4,000 approved drugs against thousands of diseases - all in record time. Host Dr. Sanjay Juneja speaks with Dr. David Fajgenbaum, Co-founder of Every Cure, to reveal how their platform delivers 75 million computed drug-disease scores directly into the hands of healthcare providers worldwide. Learn how this approach accelerates clinical decision-making, supports evidence-based research, and breaks down barriers to innovative care strategies.

May 9, 2025 • 3min
How does AI Prediction Translate to Patient Care? [David Fajgenbaum] - with Dr. Sanjay Juneja
AI prediction is transforming patient care by accelerating how life-saving treatments are identified, repurposed, and delivered to those in need. Discover how cutting-edge data analysis can uncover overlooked therapies and drive faster clinical decisions that impact real-world outcomes. Dr. Sanjay Juneja interviews Dr. David Fajgenbaum, co-founder of Every Cure, to reveal actionable strategies for leveraging artificial intelligence in healthcare systems. Learn how AI-powered frameworks are optimizing treatment selection, guiding clinical workflows, and informing executive decisions across provider networks, telehealth, laboratories, and diagnostics.

May 8, 2025 • 51min
Can AI Find the Cures We've Overlooked for Decades? - with Dr. Sanjay Juneja [FULL PODCAST]
The idea that artificial intelligence can uncover life-saving treatments hidden in plain sight is no longer science fiction. In a healthcare system that often favors costly innovation over accessible solutions, using AI to repurpose existing drugs offers a path to faster, affordable breakthroughs. Join Dr. Sanjay Juneja and Dr. David Fajgenbaum, co-founder of Every Cure, as they reveal how AI is accelerating the identification of overlooked therapies for rare and complex diseases. Learn about the critical frameworks behind drug repurposing, how predictive models like Matrix are reshaping disease treatment, and why open-source collaboration could transform healthcare delivery. If you are a physician, healthcare executive, engineer, or healthcare IT leader, this discussion offers essential insights into the future of clinical decision-making.