

AI and Healthcare
xCures
AI and Healthcare—with Mika Newton and Dr. Sanjay Juneja is an engaging interview series featuring world-renowned leaders shaping the intersection of artificial intelligence and medicine. Discover how AI is transforming healthcare today, addressing real-world challenges and improving patient outcomes.
This series caters to anyone’s listening style with bite-sized, commute-friendly insights and full-length interviews. Join co-hosts Mika Newton, CEO of xCures, and Dr. Sanjay Juneja, a globally recognized oncologist and VP of Clinical AI at Tempus AI, as they explore cutting-edge innovations with industry pioneers.
Originally launched as the TARGET: Cancer Podcast in 2021, the series evolved after 75 episodes into a comprehensive platform for AI and healthcare conversations.
This series caters to anyone’s listening style with bite-sized, commute-friendly insights and full-length interviews. Join co-hosts Mika Newton, CEO of xCures, and Dr. Sanjay Juneja, a globally recognized oncologist and VP of Clinical AI at Tempus AI, as they explore cutting-edge innovations with industry pioneers.
Originally launched as the TARGET: Cancer Podcast in 2021, the series evolved after 75 episodes into a comprehensive platform for AI and healthcare conversations.
Episodes
Mentioned books

Jun 26, 2025 • 38min
AI Makes Full Body MRI Screening Affordable - with Emi Gal
Ezra CEO Emi Gal breaks down how AI is revolutionizing full-body MRI cancer screening. Learn how FDA-cleared tools accelerate scan time, assist radiologists, and empower patients with easy-to-understand reports—all for just $499. Discover why early detection matters, especially for younger adults, and how Ezra is scaling access to lifesaving diagnostics.

Jun 25, 2025 • 6min
Inside the FDA’s Bold Elsa AI Move: Rajeev Ronanki Explains
Rajeev Ronanki, CEO of Lyric and former Elevance Health executive, unpacks what the FDA’s AI initiative—Elsa—really means for drug innovation and regulation. Rajeev outlines how the agency can use data it already has to drive smarter, faster decisions. He draws powerful parallels to autonomous vehicles and urges the FDA to embrace AI while maintaining scientific rigor.

Jun 20, 2025 • 6min
Trust, ethics, and data bias in AI
Trust in AI cannot exist without ethics - and ethics cannot exist without confronting data bias. Discover how artificial intelligence can become a force for safety, fairness, and innovation in healthcare when designed with integrity from the ground up.
In this compelling exchange, Dr. Sanjay Juneja (sjunejamd.com) interviews Rajeev Ronanki (LinkedIn), CEO of Lyric, to uncover how AI can be engineered to identify bias, self-evaluate decisions, and evolve into a trusted collaborator in clinical care. They reveal practical strategies for bias detection, the vision of an "AI Hippocratic Oath," and why ethics must precede deployment - especially in medicine.
Healthcare leaders, CIOs, CMOs, engineers, and innovators will gain critical insight into governance frameworks that future-proof AI adoption.

Jun 19, 2025 • 48min
Rajeev Ronanki: Real-Time Payer-Provider Collaboration
Rajeev Ronanki, CEO of Lyric and author of You and AI, joins Dr. Sanjay Juneja to discuss a radical rethinking of payment in healthcare. Instead of upgrading legacy systems, Rajeev proposes bypassing them using trusted AI agents that mediate between EMRs and payers. They explore real-time adjudication, the importance of trust and transparency, and how scalable AI tools can serve even community clinics. Learn how AI is reshaping healthcare finance from the ground up.

4 snips
Jun 18, 2025 • 8min
Where does the AI liability lie?
The conversation dives into the pressing legal and ethical challenges of AI in healthcare. Who holds responsibility when AI-assisted diagnoses go wrong? Insights reveal that trust and transparency are vital as healthcare institutions integrate these technologies. The need for ethical standards and thorough training for staff is emphasized, highlighting the crucial role of leadership in navigating these changes. As AI becomes a fixture in medical settings, proactive dialogue is essential for ensuring both innovation and accountability.

Jun 17, 2025 • 9min
How does the Belmont Report relate to AI ethics in healthcare?
AI is reshaping clinical care, but can we apply trusted bioethical principles to its rapid adoption? This discussion explores how the Belmont Report’s three ethical pillars - autonomy, beneficence, and justice - remain essential as AI tools enter diagnosis, decision-making, and patient communication in modern healthcare. Hosted by Mika Newton, CEO of xCures, with expert insights from Dr. Colleen Lyons, a leading clinical research ethicist, the discussion covers informed consent in AI-assisted care, transparency versus explainability, and the ethical implications of asymmetrical power in AI systems. Gain a deeper understanding of how healthcare leaders can navigate AI integration while safeguarding patient rights and institutional trust.

Jun 13, 2025 • 11min
Regulation vs Deregulation of AI in Healthcare
In this engaging discussion, Colleen Lyons, a clinical research ethicist at Champlain College, delves into the ethical implications of AI in healthcare. She and Mika Newton, CEO of xCures, warn about the risks of rapid innovation without adequate oversight. They highlight the dangers of deregulation while also addressing the hurdles of over-regulation. Explore how to navigate the complex VUCA landscape of AI, the need for ethical frameworks, and the importance of adaptive leadership in integrating transformative technologies into healthcare.

Jun 12, 2025 • 13min
How is AI used in Life sciences?
AI transforms how healthcare data is structured, analyzed and applied to clinical decision-making in life sciences. Discover how leading experts harness artificial intelligence to streamline clinical workflows, enhance data quality and accelerate actionable insights for healthcare providers and diagnostic organizations. Mika Newton, CEO of xCures, and Rajiv Haravu, SVP of Product Management at IMO Health, break down practical frameworks for applying AI to complex patient records, from medical coding to interoperability strategies. Understand how AI-driven tools empower healthcare teams to navigate vast medical datasets, improve patient care pathways and support value-based care delivery.

5 snips
Jun 6, 2025 • 9min
What are the risks of using AI in healthcare?
Join Dr. Spencer Dorn, Vice Chair at UNC Department of Medicine, as he delves into the hidden risks of AI in healthcare. He discusses how AI can undermine critical thinking and erode essential human connections between providers and patients. The conversation highlights overlooked dangers like reliance on AI-generated summaries and the erosion of professional judgment. It’s an eye-opening discussion for healthcare leaders grappling with integrating AI while maintaining the integrity of human relationships in medicine.

Jun 5, 2025 • 54min
Ethics and AI in Healthcare: A Hard Look Inside - with Dr. Colleen Lyons [FULL PODCAST]
Dr. Colleen Lyons, a clinical research ethicist with FDA experience, delves into the ethical evolution needed for AI in healthcare. She tackles critical topics like data bias, autonomy, and the responsibilities of organizations. Dr. Lyons emphasizes patient rights and the ethical complexities of AI integration in diagnostics. She also compares AI regulation to past tech innovations, advocating for a balance between oversight and creativity. Highlighting the importance of values in healthcare leadership, she calls for thoughtful implementation of technology to maintain ethical standards.