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Grow Everything Biotech Podcast

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Jun 6, 2025 • 1h 6min

132. Bond. Enzyme Bond. CurieCo's Erika Milczek on Replacing Chemicals with Biotech

Karl and Erum sit down with Erika Milczek, CEO and founder of Curie Co, to explore how synthetic biology is rewriting the rules of modern chemistry. Erika, a former Merck chemist, shares her journey from Big Pharma to launching a biotech startup that engineers enzymes to replace legacy chemicals in personal care and consumer goods. With insights grounded in regulatory shifts, manufacturing scalability, and the power of directed evolution, Erika discusses how her team is building a “biotech alternative to petroleum-based chemistry.” Whether you're curious about enzyme engineering, bioindustrial startups, or how synthetic biology can drive sustainability in everyday products, this episode delivers a high-energy, deeply technical, and inspiring dive into the future of materials innovation.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters:00:00:00 - Welcome to the Future: Setting the Stage00:00:22 - Juggling Labs, Life, and Launchpads00:01:27 - Terraforming Mars? Let’s Dream Big00:04:58 - Joe Rogan, Speciation, and Sci-Fi Tangents00:10:08 - Biotech Beauty Week: Innovation on Display00:14:13 - Meet Erika Milczek: Enzymes Over Everything00:33:03 - Feeding the Bug: The Spark Behind Discovery00:35:15 - Scaling Science: What Makes Commercialization Hard00:35:51 - Why Partnerships Make or Break Biotech00:38:02 - Following the Rules: Regulatory Shifts & Product Strategy00:42:48 - From the Lab to RTP: Building in Biotech's Backyard00:45:37 - Ecosystem First: How to Build Bio Economies00:50:01 - Fundraising Real Talk: Investors, Guts & Growth00:53:50 - Biomanufacturing Is Just Getting Started00:56:29 - Let’s Talk Packaging: Biotech’s Next Frontier00:59:52 - Wrapping Up: Lessons, Hope, and What’s NextLinks and Resources:Curie CoMars: One Day on the Red Planet (film)Marsbound by Joe Haldeman (book) The case for Mars terraforming research (Erika de Benedicts research paper)Ben Lamm on Joe Rogan ExperienceDire Wolf on the cover to Time MagazineSupplier's Day 2025 during Messaginglab's unofficial Biotech Beauty WeekCapsum - microfluidics contract manufacturingP2 company - conditioning agents⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Topics Covered: biomanufacturing, cell free biomanufacturing, enzymes, nutraceuticals, biotech, pharmaceuticals, AI, spinoutsHave a question or comment? Message us here:Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: groweverything@messaginglab.comMusic by: NihiloreProduction by: Amplafy Media
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May 30, 2025 • 58min

131. Leaf It to Science: How Foray Bioscience's Ashley Beckwith is Reforesting the Future

Karl and Erum are joined by Dr. Ashley Beckwith, Founder & CEO of Foray Bioscience, for a wide-ranging conversation on the future of biomaterials and the emerging role of plant culture in shaping it. Ashley unpacks how Foray is pioneering new approaches to growing materials directly from plant cells, redefining how we produce, restore, and preserve biological resources. The episode explores the untapped potential of plant culture in bioproduction, ecosystem restoration, and biodiversity preservation when applied with care and intention. Ashley shares her path from growing up in Colorado to pursuing mechanical engineering and bioengineering, and how that interdisciplinary foundation ultimately led her to start Foray. Throughout the conversation, Ashley describes how Foray is building the foundational infrastructure for plant culture. The company develops core capabilities from the ground up and then partners with others to scale and specialize applications. This platform-based approach reflects Foray’s belief that unlocking the full potential of plant systems requires a collaborative ecosystem rather than the efforts of a single company.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters:00:00:00 - Kicking Off with a Big Question: Can We Rebuild Nature from the Cell Up?00:00:15 - Summer Vibes and Bio Talk: Memorial Day Weekend Catch-Up00:00:46 - Synbio Beta Sparks: The Pulse of Next-Gen Biotech00:02:27 - Argentina to IndieBio: The Unstoppable Founders You Need to Know00:04:01 - Biotech Gets Corporate: The Rise of Strategic Venture Funds00:05:11 - Deal Flow & Discovery: HC Wainwright’s Biotech Bash00:08:18 - Brooklyn Bio Buzz: A Night Out with the Community00:10:24 - From the Explorers Club to Seed Vaults: Sci-Fi Meets Soil00:11:22 - Meet Dr. Asheley Beckwith: Engineering the Future of Fashion with Cells00:27:35 - Biology Meets Ecology: How Engineered Plants Could Aid Conservation00:30:12 - Sci-Fi to Soil: Fabricating Seeds for Extinct Ecosystems00:32:21 - The Wild Frontier: Overcoming the Barriers in Plant Cell Cultivation00:45:52 - Nature Meets Code: Using AI to Unlock the Secrets of Plants00:50:20 - Imagining Tomorrow: The Vision Behind ForayBio’s Living Materials00:51:50 - Full Circle: Final Reflections from the Edge of BiodesignLinks and Resources:⁠Foray BiosciencesSF500 (Argentinian Global Venture Fund)Syensqo Corporate Venture FundH.C. WainwrightUniversity of Vermont - Dr. Steve KellerUniversity of Maryland - Dr. Matt Fitzpatrick⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Topics Covered: biomanufacturing, cell free biomanufacturing, enzymes, nutraceuticals, biotech, pharmaceuticals, AI, spinoutsHave a question or comment? Message us here:Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: groweverything@messaginglab.comMusic by: NihiloreProduction by: Amplafy Media
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May 23, 2025 • 1h 1min

130. SynBioBeta 2025 Recap: Hyperscale Biology

This lively recap dives into the highlights of SynBioBeta 2025. It features Drew Endy’s bold vision for localized manufacturing and the transformative role of AI in synthetic biology. The discussion touches on the intersection of biology and geopolitics, emphasizing how innovation can reshape the bioeconomy. Insights into immune system reprogramming and advancements in protein design showcase the potential of biomanufacturing. A focus on collaboration and the importance of community engagement rounds out the conversation, making for an inspiring listen.
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May 16, 2025 • 51min

129. No Cells? No Problem! eXoZymes' Michael Heltzen on the Future of Microbe-Free Biotech

Erum sits down with Michael Heltzen, CEO of eXoZymes, to dive into the transformative world of cell-free biomanufacturing. Michael shares the origin story of ExoZymes—from a student bioengineering dream at UCLA to ringing the NASDAQ bell—and unpacks why scalability, sustainability, and design thinking are central to the next generation of biotech. If you're curious about how biology can be engineered without living cells, what it takes to commercialize breakthrough science, or how new business models in synthetic biology are emerging, this is the episode for you. Get ready to rethink what’s possible when biology breaks free from the cell wall.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters:00:00:00 – Unlocking a New Era: Rethinking Natural Resources for the Future00:00:17 – SynBioBeta Afterglow: Late Nights, Big Ideas, and Bio Buzz00:02:39 – Breaking the Cell Wall: The Power of Cell-Free Biomanufacturing00:03:33 – Meet Michael Heltzen: The Visionary Behind the Next Bio Revolution00:09:54 – Inside NCTX: The Molecule That Might Change Everything00:16:06 – No Scale, No Impact: Tackling SynBio’s Toughest Bottlenecks00:26:43 – From Supplements to Cures: Bio’s Leap Across Sectors00:27:19 – AI x Enzymes: Cracking Nature’s Code in Real Time00:28:06 – Making Biology Predictable: ML Meets Molecular Design00:30:14 – Faster Than Nature: How AI Shrinks Production Timelines00:33:29 – Go-to-Market Moves: Biotech Strategy for the Real World00:36:07 – Bio Click™: Targeted Enzymes with Industrial Precision00:38:38 – Life After the Bell: IPOs, Growth, and Big Bio Energy00:42:29 – Zooming Out: Big-Picture Thinking for What Comes NextLinks and Resources:eXoZymesNCTx BioClick⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Topics Covered: biomanufacturing, cell free biomanufacturing, enzymes, nutraceuticals, biotech, pharmaceuticals, AI, spinoutsHave a question or comment? Message us here:Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: groweverything@messaginglab.comMusic by: NihiloreProduction by: Amplafy Media
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May 9, 2025 • 1h 19min

128. Replay of Synbiobeta 2024 Recap with Fresh Commentary

Karl and Erum revisit their energetic and unfiltered recap of SynBioBeta 2024. With candid reflections on the conference and the broader synthetic biology ecosystem, they spotlight key trends including the rise of accessible community bio labs, decentralized events like the Biopunk gathering, and the convergence of deep tech and culture. This is not your average event recap—it's a tour through the evolving architecture of the bioeconomy, from the mainstream to the fringes. Whether you missed the event or want to relive the highlights, this episode captures the pulse of where biotech is heading.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters:00:00:00 - Welcome Back! Why This Replay Matters00:00:14 - SynBioBeta 2024: The Moments That Blew Our Minds00:01:40 - The Biopunk Underground: Bio for All, No Badge Required00:03:11 - Serendipity, Old Friends & Building the SynBio Tribe00:05:43 - Black Mirror or Just the Future? Wild Tech at the Edge of Medicine00:08:04 - AI-Generated Soundtracks & the New Synesthetic Biology00:12:16 - Brewing Bio at Home: DIY Fermentation, Micro-Growth & More00:16:05 - SynBioBeta 2025 Teasers & The AI Takeover of Bio Design00:25:26 - When Space Meets Biomanufacturing: New Frontiers in Orbit00:33:12 - From Mycelium to Mind Expansion: The Psychedelic Thread00:42:08 - Big Names, Bigger Bets: Who Showed Up and Why It Matters00:42:43 - L’Oréal Goes Biotech: The Beauty of Strategic Collabs00:44:31 - Are You a Platform or a Product? The Debate That Won’t Die00:46:48 - Where the Money Is: What Investors Really Want in 202500:51:28 - How to Crush a Conference (Without Burning Out)00:55:01 - CEO Power Lunches and Glowing Plants: Yes, Really00:59:46 - When Bioluminescence Meets Culture: Awe, Meaning & Light01:06:16 - Heroes, Hacks, and the People Moving Bio Forward01:09:33 - Swag, Specimens & Scenes from the Expo Hall01:15:28 - Looking Ahead: What’s Next in the Bio RevolutionLinks and Resources:MessaginglabBiopunk Lab What Are Binaural Beats?Genspace ⁠⁠⁠⁠⁠⁠⁠⁠Topics Covered: biomanufacturing, synbiobeta, recaps, black mirror, functional musicHave a question or comment? Message us here:Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: groweverything@messaginglab.comMusic by: NihiloreProduction by: Amplafy Media
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May 2, 2025 • 23min

127. Chain Reaction: Orchestrating BioInnovation Without Missing a Beat – with MessagingLab’s Erum & Karl

Erum and Karl break down a concept they've lived and breathed—but rarely spelled out: orchestration. If you're building a startup in synthetic biology or advanced materials, this is a must-listen deep dive into how influence is built before your product lands or your funding closes. They pull back the curtain on how to create "value chain syndicates," why intros aren’t just intros, and how real biotech momentum comes from aligning stakeholders across an entire ecosystem—not just impressing one customer.Taped just ahead of SynBioBeta 2025, this episode crackles with tactical wisdom, from designing credibility scaffolds to creating the conditions for inbound interest before traditional biz dev ever kicks in. Orchestration, they argue, is the true differentiator in biotech's current era—more critical than science alone.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters:00:00:00 – Gearing Up: SynBioBeta Buzz and Real-World Prep00:02:18 – Why Orchestration Is Biotech’s Unspoken Superpower00:05:25 – What’s Really Blocking Biotech from Breaking Through?00:08:10 – K18 Hair: A Masterclass in Vertical Bio-Play00:10:09 – Ecosystem Marketing: The Influence Strategy No One Talks About00:16:15 – How to Engineer Ecosystems That Actually Work00:22:20 – What’s Peaking in Biotech? Trends You Can’t Ignore00:27:08 – The Orchestration Era: Your Next Move Starts NowLinks and Resources:MessaginglabNational Security Commission on Emerging Biotechnology's Report: Charting the Future of Biotechnology⁠⁠⁠⁠⁠⁠⁠⁠Topics Covered: biomanufacturing, value chain orchestration, supply chains, supply networks, ecosystem building, ecosystem marketing, influencing, business development, strategyHave a question or comment? Message us here:Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: groweverything@messaginglab.comMusic by: NihiloreProduction by: Amplafy Media
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Apr 25, 2025 • 44min

126. Sizzling Success: Eben Bayer of MyForest Foods on Scaling Mycelium Magic

Karl and Erum reconnect with Eben Bayer, Board Chair at MyForest Foods, for a compelling follow-up conversation on the evolution of mycelium-based food products. Eben dives deep into the scaling journey of MyBacon, a plant-based bacon alternative created through solid-state fermentation using gourmet mushroom mycelium. From early experiments producing just six packs a week to now operating at multiple farms across North America and Europe, Eben outlines the technical, economic, and operational hurdles his team has overcome. Listeners will discover how MyForest Foods is pioneering a distributed, farm-based manufacturing model and why MyBacon is outpacing pork bacon in select markets. If you're curious about biomaterials, novel fermentation tech, or the practical future of sustainable food systems, this episode offers a front-row seat to the revolution.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters:00:00:00 - Liftoff! Imagining the Future with Space Elevators00:00:15 - Back in Action: Your Favorite Bio-Futurists Return00:00:31 - Erum’s Arctic Escape: Sauna Talks & Synbio Dreams00:02:27 - Biotech Bonding: Unexpected Encounters in the North00:04:39 - From Lava Fields to Lab Ideas: Iceland Inspires00:04:48 - Travel Hack: How ChatGPT Became Our Digital Tour Guide00:06:59 - Survival, Science & Synbio: Adventures at the Edge00:09:37 - Deep Dive: Oceans, Algae & the Blue Carbon Breakthrough00:12:29 - Enter Eben Bayer: Mycelium Magic and Fungi Futures00:24:22 - Farming the Future: A Global Mycelium Network Emerges00:25:13 - Teaming Up: Mycelium Hits the Mainstream Food Scene00:26:30 - Eco-Revolution: Why Fungi Might Just Save the Planet00:27:52 - What’s Next? The Tasty Future of Bio-Engineered Foods00:29:35 - Fungi Meets Firmware: Mycelium, Tech & the Rise of Bio-AI00:30:51 - From Farm to Factory: The Scale-Up Challenge Conquered00:32:41 - Off-World Growth: Mycelium and the Final Frontier00:38:30 - Wrap-Up: Big Ideas, Bold Futures, and What’s Coming NextLinks and Resources:MyForest FoodsEcovativeHotdogJudge on InstagramExtremophiles on Mars: One group of living   things that may be able to survive these extreme conditions is lichens,Blue Carbon documentary- carbon dioxide that is absorbed from the atmosphere and stored in the ocean. ⁠⁠⁠⁠Topics Covered: biomanufacturing, mycelium, biomaterials, ecovative, bacon, mycelium bacon, plant based foods. Have a question or comment? Message us here:Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: groweverything@messaginglab.comMusic by: NihiloreProduction by: Amplafy Media
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Apr 18, 2025 • 1h 4min

125. The Synbio Symphony: SynBioBeta’s John Cumbers Harmonizes Biology and Industry

Karl and Erum welcome back Dr. John Cumbers—founder of SynBioBeta and Biological Enlightenment Studios—to dive deep into the transformative power of synthetic biology. From designing personalized proteins and sustainable materials to programming life for space exploration, John unpacks why synthetic biology could be the defining technology of our century. The conversation spans the central dogma, programmable cells, AI-designed genomes, and even the ethics of growing brainless human clones. With themes ranging from planetary health to Pixar-style science storytelling, this episode offers a biologically enlightened vision of a future where we grow everything—from meat to materials to machines.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters:00:00:00 – Welcome to the Club: The Biologically Enlightened Begin00:00:26 – Biotech Meets Copenhagen: Global R&D, Beer, and Bold Ideas00:01:53 – AI Roasts, Inside Jokes, and the Business of Podcasting00:04:00 – Dire Wolves, CRISPR, and the Wild World of De-Extinction00:09:49 – Microscopes, Microbes, and the Future of Biotech Gaming00:12:14 – Enter John Cumbers: Mastermind of Synthetic Biology00:31:22 – Hyperscale Biology: AI-Bio Collisions at the Frontier00:32:16 – From Intimidation to Innovation: Embracing AI in the Lab00:34:24 – Beyond the Hype: AI, Quantum, and the Bio Black Box00:36:13 – Remixing Life Itself: Non-Canonical Amino Acids Take the Stage00:41:50 – From Niche to Mainstream: Biotech’s Cultural Awakening00:45:12 – Rewriting the Future: Bio Strategies for a Greener Planet00:48:39 – Too Radical to Fail? Brain Swaps and Body Clones00:54:05 – SynBioBeta 2025: The Party, The Panels, The Possibilities00:56:58 – What We Learned: Final Reflections and Nerdy JoyLinks and Resources:Synbiobeta (Listen to this episode for a special discount to attend! You're welcome ;))Common Side EffectsTime Magazine Cover of Colossal De-extincting the dire wolfDehli’s laptop repair marketOsmos Video Game⁠Topics Covered: synbio, conferences, biotech, community, AI in bio, space biotech, biotech education, biotech edutainment. Have a question or comment? Message us here:Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠Email: groweverything@messaginglab.comMusic by: NihiloreProduction by: Amplafy Media
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Apr 11, 2025 • 1h 6min

124. Cell-ebrating Success: Ilan Sobel Blends Science and Strategy to Scale-up BioHarvest

What if you could grow health-boosting compounds—not in fields, but in bioreactors—using the power of plant cells? In this episode, Karl and Erum sit down with Ilan Sobel, CEO of BioHarvest, to explore how the company is reshaping biotech, nutraceuticals, and biomanufacturing. From leveraging botanical synthesis to create highly bioavailable compounds like piceid resveratrol, to scaling sustainable DTC operations that rival software margins, Ilan reveals how BioHarvest is closing the gap between nature, science, and commerce. Hear how this Coca-Cola veteran is building a biological infrastructure poised to disrupt pharma, food, and beyond—one cell at a time.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters:00:00:00 - Kicking Off with Biotech That Prints Money00:00:21 - $9 Trillion Vanishes: Markets, Mayhem, and Monday Mood00:00:36 - Brooklyn Birthdays, Bio Buzz & Citizen Scientists Unite00:02:24 - Tariffs, Pharma, and the Future of Drug Supply Chains00:04:20 - Reddit Rabbit Holes and Underrated Science That Could Change Everything00:06:49 - Pharma’s Dirty Secret: Why Cures Don’t Always Win00:09:39 - Meet Ilan Sobel: From Coca-Cola Exec to Biotech World-Changer00:19:13 - What the Heck Is Botanical Synthesis? (And Why It’s a Game-Changer)00:26:46 - Tiny Footprint, Massive Impact: Economics That Would Make Silicon Valley Jealous00:29:02 - How a Grape Cell Became the King of Blood Flow Supplements00:35:09 - Why Longevity Starts with Blood, Not Kale00:37:32 - The Secret Sauce Behind Supplements That Actually Work00:38:55 - How BioHarvest Orchestrated a Biotech Masterpiece00:40:20 - From Plant Cells to Profit: Scaling Biotech Like a Pro00:43:10 - Open Sourcing the Future: CDMO Deals with Global Impact00:48:47 - Making Sweeteners Smarter (And Actually Tasty)00:51:35 - Building the Tesla of Biomanufacturing—Globally00:57:39 - What’s Next for BioHarvest? Legacy, Longevity, and Global ScaleLinks and Resources:BioHarvestVinia.comPwC’s US Tariff Industry Analysis – Pharmaceutical, Life Science, and Medical DeviceReddit: Scientific Ideas that haven’t gotten enough tractionCommon Side Effects (tv series)Genesis Machine (book)Topics Covered: biomanufacturing, botanical cellular synthesis, plant biology, phytonutrients, sweet proteins,  distributed biomanufacturing, direct to consumer biotechHave a question or comment? Message us here:Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠  / ⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠Email: groweverything@messaginglab.comMusic by: NihiloreProduction by: Amplafy Media
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Apr 4, 2025 • 1h 1min

123. From Gas to Glam: Molly Morse Discusses Mango Materials' Biodegradable Innovations

In this episode of Grow Everything, Karl and Erum dive deep into the transformative world of biomanufacturing with Molly Morse, CEO and Co-founder of Mango Materials. Molly shares how her team is using methane—one of the most potent greenhouse gases—as a feedstock to create PHAs, a class of biodegradable bioplastics. From wastewater treatment partnerships to collaboration with brands like Allbirds and Stella McCartney, Mango Materials is setting a new standard in sustainable innovation. The conversation spans synthetic biology, microbial fermentation, the challenges of scaling, and even bioplastics in space. If you're passionate about circular economies, advanced materials, or cutting-edge climate tech, this episode is for you.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠ Chapters:00:00:00 - Kicking Things Off: Weekend Tales & Seal Surprises00:00:36 - A Shiny Seal, Beach Drama & Wildlife Wisdom00:02:51 - AI is Basically Michael Scott… And That’s a Good Thing00:04:40 - Can We Trust World Leaders Taking Advice from ChatGPT?00:07:44 - AI That Talks Back: Selling Smarter with Conversational Tech00:09:35 - Muscles Made in a Lab? Welcome to the Future of Biology00:12:36 - Molly Morse Joins: Turning Methane into Magic with Mango Materials00:29:33 - Waste to Wealth: How Municipal Methane Becomes a Revenue Stream00:30:16 - From Landfills to Livestock: Where the Methane Goldmine Is00:31:33 - Scaling Science: The Real Talk Behind Biomanufacturing Challenges00:33:47 - Zero Gravity, Big Ideas: Mango’s Mission in Space00:38:34 - From Microbes to Market: Scaling PHA Pellet Production00:46:11 - What Does “Biodegradable” Really Mean? Let’s Break It Down00:51:35 - Big Picture: What’s Next for Mango Materials and Biotech InnovationLinks and Resources:Mango MaterialsMichael Scott Guide to AI TerminologiesEngineered Muscles That Move Like the Real Thing? MIT Just Made It HappenProtoclone: Bipedal Musculoskeletal Android V1 by Clone RoboticsMango Materials Zero G Experience on G-Force One to test fermentation on a membrane-based bioreactor system in weightlessnessTopics Covered: biomanufacturing, biomaterials, greenhouse gas, waste to value, biopolymersHave a question or comment? Message us here:Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠  / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠Email: groweverything@messaginglab.comMusic by: NihiloreProduction by: Amplafy Media

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