Discovery

What does it take to earn the nickname, ‘The Leonardo da Vinci of heart surgery’?That's the moniker given to today's guest - a man who pioneered high-profile and often controversial procedures, but also helped drive huge medical progress; carrying out around 2,000 heart transplants and 400 dual heart-lung transplants during his 60-year career.Sir Magdi Yacoub is Emeritus Professor of Cardiothoracic Surgery at Imperial College London, and Director of Research at Harefield Hospital’s Magdi Yacoub Institute. Inspired by a surgeon father and impacted by the tragic early death of his aunt from a heart condition, his medical career includes various surgical firsts alongside numerous research projects, to further our understanding of and ability to treat heart disease. He headed up the teams that discovered it is possible to reverse heart failure, and that successfully grew part of a human heart valve from stem cells for the first time.But it hasn't always been plain sailing. At times, his work – such as early, unsuccessful transplant attempts, or using a baboon as a life-support system for a baby – attracted serious public criticism.Speaking to Professor Jim Al-Khalili, Sir Magdi reflects on the highs and lows of his cardio career, and offers his advice to the next generation of surgeons and researchers hoping to make their mark in heart medicine.Presented by Jim Al-Khalili Produced by Lucy Taylor Reversion for World Service by Minnie Harrop

Claudia de Rham has rather an unusual relationship with gravity.While she has spent her career exploring its fundamental nature, much of her free time has involved trying to defy it - from scuba diving in the Indian Ocean to piloting small aircraft over the Canadian waterfalls. Her ultimate ambition was to escape gravity’s clutches altogether and become an astronaut, a dream that was snatched away by an unlikely twist of fate.However, Claudia has no regrets - and says defying gravity for much of her life has helped her to truly understand it.As Professor of theoretical physics at Imperial College London, she now grapples with deep mathematics, where the fields of particle physics, gravity and cosmology intersect, on a quest to understand how the universe really works. She is a pioneer of the theory of massive gravity, a theory which could take us beyond even Einstein’s theory of relativity and shed light on why the universe is expanding at an ever-increasing rate.Presented by Jim Al-Khalili Produced for BBC Studios by Beth Eastwood Reversion for World Service by Minnie Harrop

When you think of Artificial Intelligence, does it inspire confidence, or concern?Although it's now generally accepted that this technology will play a major role in our future, a lot of conversations around AI and machine learning come back to the argument over us losing control and robots taking over.Happily, Neil Lawrence has a more optimistic view of the power of AI, and how we might navigate the potential pitfalls. Neil is the DeepMind Professor of Machine Learning at the University of Cambridge, and over the course of his career has been involved in deploying AI and machine learning in both academic and commercial scenarios, with a stint at Amazon as well as working across fields as varied as movie animation, Formula 1 strategy, and medical research.Speaking with Professor Jim Al-Khalili, Neil says ultimately his efforts are all about making a difference to our everyday lives - and that we need to learn how to embrace AI, albeit with a healthy dollop of scepticism; not least when it comes to how our data is used, and the power of 'the digital oligarchy'...Presented by Jim Al-Khalili Produced for BBC Studios by Lucy Taylor Reversion for World Service by Minnie Harrop

A frozen, white world at the far-reaches of the globe, where you're surrounded by snow and silence, might sound rather appealing. Factor in temperatures that drop to -57°C and a few of us might be put off - but for glaciologist Liz Morris, that's very much her happy place.Liz is an Emeritus Associate at the University of Cambridge’s Scott Polar Research Institute, and was among the first British women scientists to work on the planet’s coldest continent, Antarctica. Over the course of her career, Liz has gathered vital data on polar ice sheets and how they’re affected by climate change. She's also made numerous research trips across the Greenland Ice Shelf, and has a glacier named after her in Antarctica.In conversation with Professor Jim Al-Khalili, Liz discusses her fascination with glaciers and ice - and explains her unwavering determination to break into what was once a heavily male-dominated field.Presented by Jim Al-Khalili Produced for BBC Studios by Lucy Taylor Reversion for World Service by Minnie Harrop

Welcome to a world where medicine meets politics: a space that brings together scientific research, government wrangling, public push-back and healthcare conspiracies…Dr Anthony Fauci was the Director of America’s National Institute of Allergy and Infectious Diseases for nearly four decades, during which time he not only helped study, treat and prevent viruses such as HIV/AIDS and Covid-19; he also advised seven US Presidents, from Ronald Regan through to Joe Biden.Along the way, Tony Fauci's picked up a public profile and taken a fair amount of flack; not least because of his complicated relationship with President Donald Trump. But he's also made great strides in medical research and policy, from working with activists who initially challenged him on the government response to HIV/AIDS - to spearheading the USA's PEPFAR project to share vital medication with developing nations.In a candid conversation with Professor Jim Al-Khalili, Tony discusses his childhood in Brooklyn, the dark early days of the HIV/AIDS epidemic and lessons from the Covid-19.Presented by Jim Al-Khalili Produced for BBC Studios by Lucy Taylor Reversion for World Service by Minnie Harrop

Join entomologist Julio Rivera, a specialist in praying mantises from the Université de Montréal, and Bianca Greyvenstein, a postdoctoral fellow at North-West University, as they unravel the mysteries of these incredible insects. Discover their astonishing predatory skills, including hunting prey much larger than themselves. Dive into their cultural significance and fascinating folklore from around the world. They also explore the mantises' crucial role in agriculture and their unique biomaterials that hold promise for future innovations.

Gareth Mann, the Leopard Program Director for Panthera, and Charlotte Searle, a postdoctoral researcher at the University of Oxford, share their expertise on leopards. They delve into the unique traits of these elusive big cats, including their distinct roars and camouflage skills. The conversation highlights the complexities of their solitary hunting behaviors and their territories in Tanzania. They also explore the challenges of conserving the Arabian leopard, discussing innovative solutions like synthetic fur capes to help combat poaching and support biodiversity.

Yael Velleman, Director of Policy and Innovation at Unlimit Health, tackles issues of water access and sanitation. Anthony Acciavatti, Associate Professor at Yale, shares insights from his exhibition on groundwater's historical significance. Neil Turner, a nephrologist, discusses the vital role of hydration for kidney health. They explore the global water crisis, the impact of climate change on water availability, and the myths around hydration. The conversation culminates in a call for awareness and action to ensure equitable access to clean water for all.

Eduardo Alvarez, founder of EarthMatters.org, and biologist Helena Aguiar-Silva, a researcher at the National Institute for Amazonian Research, dive deep into the world of harpy eagles. They discuss the eagle's impressive adaptations and cultural significance, as well as how deforestation forces these apex predators to shift their diets. The innovators explore groundbreaking GPS technology's role in tracking these majestic birds and the collaborative conservation efforts aimed at protecting their rainforest habitat.

Investigating the black-and-white apex predator of the sea – the killer whale! Able to predate even great white sharks, this marine mammal is the largest member of the dolphin family. From tropical seas, to the Arctic and Antarctic, killer whales (or orcas) are found across the world. Living in family groups and often led by a post-menopausal matriarch, killer whales have passed on their hunting methods, which vary depending on which prey they specialise in hunting, through the generations.Presenter Adam Hart finds out about the killer whales incredible social behaviours (such as wearing salmon as hats) and hears how a dog is helping killer whale researchers access a gold mine of information about this predator. He also hears what challenges killer whale populations are facing and why killer whales may be attacking boats off the coast of the Iberian peninsula.Contributors:Dr. Leigh Hickmott, whale biologist and conservationist, who is an expert on Pack Ice killer whales, and whose research uses them as indicators to assess human disturbance of marine habitats.Dr. Deborah Giles, who is an expert on Southern Resident killer whales, based with the SeaDoc Society, a program of the Karen C. Drayer Wildlife Health Center at the UC Davis School of Veterinary Medicine.Presenter: Professor Adam Hart Producer: Jonathan Blackwell(Photo: Killer Whales, Credit: Serge MELESAN via Getty Images)