BBC Inside Science

Dr Alex Lathbridge with your peek at the week in science.This week in the House of Commons Matt Hancock announced a new variant in the Covid virus, discovered to be spreading through the south east of the UK. As Professor Jonathan Ball of the University of Nottingham describes, there have been many slight mutations and changes to the DNA in the virus since it first emerged, and most are of no added danger. But it is important that new ones - and new combinations of them - are tracked through collaborations and networks such as COG-UK, who provide an almost real-time track of the spread of new mutations. The new one this week is of some interest as it involves a slight change to the protein of the binding area on the virus, but much lab work remains to be done,Is an angry face always an angry face? A paper in the Journal Nature this week uses Machine Learning to scan millions of videos of faces on YouTube to shed light on an old problem - the universality of facial expressions in people. The authors - working with Google - suggest that broadly speaking, in a number of contexts such as weddings and sporting events, people in much of the world tend to pull the same faces. But as Lisa Feldman Barrett - who wrote an accompanying commentary in the same journal - suggests, the way Machine Learning approaches in this area require very human perceptions to train the algorithm in the first place, means care must be taken before inferring too much.This year BBC Inside Science has been showcasing some of the mystery objects the Science Museum has uncovered in the course of moving its collections to a new home in Wroughton, Wiltshire. Jessica Bradford talks to Alex about our next one. If you have any ideas what it might be for, you can let them know by dropping a note or memory to mysteryobject@sciencemuseum.ac.uk Presented by Alex Lathbridge Produced by Alex MansfieldMade in Association with The Open University

Dr Alex Lathbridge brings you the week in science.As the first COVID vaccines are delivered this week hastening the first glimmers of a return to normal life, is it too soon to be thinking about other future threats to humanity? James Arbuthnot, chair of a House of Lords select committee tasked to look at risk planning, and fellow committee member Martin Rees discuss their meeting this week and the assessment of the scientists invited to share their interpretations of future threats like AI, solar flares and volcanic eruptions. They are inviting evidence submissions until January 28th 2021.The Millennium Seed Bank was setup as a safety net to protect and conserve rare, threatened and useful wild plants for generations to come. As it celebrates 20 years of operation it can claim to host 16 per cent of the world’s bankable flora in its sturdy underground vaults. Alex heads down to the Royal Botanic Gardens in Wakehurst, Sussex, and meets the team coaxing seeds to life to check their viability or using cryopreserving on those seeds less convivial to being preserved. One key project is protecting farmed crops that have lost genetic diversity over time and are at risk from climate change. Through collecting and researching the wild ‘cousins’ of our modern day crops Wakehurst, Kew Gardens and its partners are researching and harnessing the resilient traits found in these less pampered crop relatives. Treezilla.org is a citizen science project designed to increase understanding of all the urban tress in the UK. Scientists, together with the public, are getting their tape measures out and cataloguing the trees to better ascertain how they influence the environment in towns and cities across the UK, to map their ages, species, sizes and health, and to help future planners to put the knowledge to work. Kate Hand is a researcher at the Open University who is looking at ways to increase our knowledge of the values trees bring to our urban environments – specifically through the lens of Milton Keynes which, it transpires, is quite the urban arboretum.

Has one of the biggest problems in biology been solved by AI? Dr Alex Lathbridge brings you the week in science.This week google's Deep Mind team presented results of their latest efforts at cracking the 50 year old problem of Protein Folding. AlphaFold has built on previous success at predicting the 3D structures of biological proteins from just knowing the sequence of amino acids of which it is made. It is a computational problem that thousands of researchers around the world have been trying to solve for decades. There are millions of different proteins doing all the work in living cells, but simply knowing what their constituent chemicals are is not enough to understand how they are shaped, and therefore how they work. Scientists are optimistic that solving the problem will herald a new era in medicine, agriculture and even sustainable recycling. Prof John Moult, founding chair of CASP - the international body that monitors progress in the field, tells of the remarkable breakthrough being discussed this week.Whilst China is trying to bring back samples of the moon this week, a much longer-lived space mission to an asteroid hopes this weekend to return samples of the earliest bits of the solar system to earth. Hyabusa 2 will complete a 6 year mission, Japanese scientists hope, this weekend when a small package of asteroid sample drops into the atmosphere above Australia on Sunday morning.And as students across the UK prepare to make their ways home for the holidays, GP Margaret McCartney and Kavita Vedhara of Nottingham University discuss some of the challenges of fast mass covid testing and false negatives.Presented by Alex Lathbridge Produced by Alex Mansfield and Melanie Brown.

Last weekend a joint European-US satellite blasted into space to begin its mission - monitoring the oceans back here on earth. Sentinel 6 Michael Freilich is one of a long line of satellites and has a striking design – appearing like a bright gold farmyard barn with a big pitched roof. Anand Jagatia speaks to Dr Ralph Cordey at Airbus Space and Defence about the latest design iteration and the technology on-board. Oceanographer Professor Penny Holiday from the National Oceanography Centre explains how Sentinel 6’s readings will enhance understanding of sea-level rises and give more detail about the currents in our oceans.We journey back to the cosmic ‘Dark Ages’, a period of time that we know hardly anything about. Dr Emma Chapman is an astrophysicist at Imperial College London who has written a book ‘First Light: Switching on Stars at the Dawn of Time’ to throw light on this illusive chapter in the history of our universe. How close are scientists to finding the first stars?With ambitious new government targets to end the sale of petrol and diesel cars by 2030 how ready are electric cars to fill the gap? One key area many companies are trying to improve are the batteries powering electric vehicles. Peter Bruce, professor of materials science from Oxford University and chief scientist at the Faraday Institution has been working on rechargeable lithium ion energy storage since the 1990s. He speaks with Anand about the current limitations and the most recent developments in battery research and development.Presented by Anand Jagatia Produced by Melanie Brown

Earlier this month, the government rolled out a pilot in Liverpool for ‘Operation Moonshot’, their proposal to spend £100 billion pounds to regularly test the entire UK population for SARS CoV 2. Anand Jagatia speaks to screening expert Dr Angela Raffle and medical test evaluator Professor Jon Deeks from the University of Birmingham. They share their concerns about the scheme and the benefits it may bring.A year ago, BBC Inside Science helped launch the Big Compost Experiment, a citizen science project run by a team at UCL. They asked the public to get involved by providing information about the matter that’s rotting in compost piles around the UK. What do people think about biodegradable plastics and what actually happens to them – do they break down like they are supposed to? Anand finds out about the results so far .from Mark Miodownik, one of the creators of this project, We travel back in time to 66 million years ago, when a massive meteorite smacked into the Gulf of Mexico bringing the reign of the dinosaurs to a cataclysmic conclusion. It was also the beginning of a new chapter in the history of life on Earth. The impact may have caused an apocalypse of earthquakes, tsunamis, volcanic eruptions and the darkness of a nuclear winter; but it may also have created a haven for new life forms to emerge. Roland Pease has been talking to two geologists, David Kring and Tim Bralower, who have found evidence for the return of life in the crater after the carnage of the meteorite strike.Presented by Anand Jagatia Produced by Melanie Brown

Scientists this week announced hopeful results in two of the big COVID-19 vaccination trials. Trudie Lang, Professor of Global Health at the Nuffield Department of Medicine, Oxford, describes some of the methodology used, what the efficacy statistic means, and how the novel approach of inserting mRNA rather than deactivated virus parts, is so exciting.Prof Charles Cockell has been investigating how bacteria might be grown in space on lumps of asteroid to extract precious minerals, and as Kim McAllister reports, his lab is itself in orbit.And it is just a few weeks since the UK, and several other countries, signed up to a set of bilateral agreements with the US called the Artemis Accords. These are an attempt to update previous outer space treaties on how countries - and indeed companies - might mine and use resources in space, given that no-one can currently legally claim sovereignty. As Dr Thomas Cheney of the Open University and Prof Jill Stuart of the LSE describe, the Accords have been greeted in certain quarters with some discord.Presented by Marnie Chesterton Produced by Alex MansfieldMade in collaboration with The Open University.

We know that children can catch the SarsCov2 virus, even though adverse side effects are incredibly rare. But what isn't clear is how likely they are to transmit the virus? If you’re a parent, are you in danger of catching the virus, maybe brought home from school by your child? A large study, using the anonymised health experiences of around 12 million adults registered with GPs in England, has just been published that explores that question. Dr Laurie Tomlinson, of London School of Hygiene and Tropical Medicine, explains the findings.On October 30th a magnitude 7 earthquake under the Aegean Sea created devastation when it struck Turkish city of Izmir. Marnie discusses the nature of the earthquake and why this area is so seismically active with Dr Laura Gregory, a geologist at Leeds University who has studied the rocks in the region. Professor Tiziana Rossetto, an expert in earthquake engineering at UCL, talks about a recent survey and intervention she carried out with the residents of Izmir to help them prepare for earthquakes.In the last of our interviews with the authors shortlisted for the Royal Society Insight Investment Science Book Prize 2020 Adam Rutherford meets the winner, Dr Camilla Pang. At the age of eight she was diagnosed with autism spectrum disorder. Struggling to understand the world around her, she went in search of a blueprint or a manual that would help her navigate the curious world of human social customs. Nearly two decades on, Camilla has produced one herself, entitled: Explaining Humans: What Science Can Teach Us about Life, Love and Relationships. Presenter: Marnie Chesterton Editor: Deborah Cohen

Marnie Chesterton presents an update on the week's science.Behind your eyes, above your mouth but below the brain, two 3cm saliva glands have been hiding since anatomy began. So reports a new study by Matthijs Valstar and Wouter Vogel of The Netherlands Cancer Institute. They describe to Marnie how they found these hitherto unnoticed glands, and importantly how knowledge of these will help people treated for head and neck cancers to get on with their lives in the future. It may be that radiotherapies have been inadvertantly destroying the glands in the past, leading to difficulties eating and breathing. Bill Bryson is the latest in BBC Inside Science's flick through 2020's Royal Society Book Prize shortlisted authors. He talks to Adam Rutherford about his work, The Body: A Guide for Occupants, and his continuing awe at its complexity.And Roland Pease reports on evidence of a return to the Dust Bowl conditions that so devastated agriculture and livelihoods in the US mid-west during the 1930s. This time, we can see the dust storms gathering from space. But that doesn't mean that intensive agriculture, extreme weather and climate change aren't combining to do what might be a re-run of some of the disastrous issues from those years.Presented by Marnie Chesterton Produced by Alex MansfieldProduced in collaboration with The Open University.

If you contracted COVID will you then be protected from further infections and illness from SARS-CoV-2 in the future? We’re starting to hear about cases of people being infected by the novel coronavirus for a second time. A handful of these cases have been published in peer reviewed journals. Nottingham University’s Professor of Virology Jonathan Ball discusses how big the problem of reinfection might be. Is it likely to be a common event which could hamper efforts to bring the pandemic under control? In the latest in our series interviewing the shortlisted authors from this year’s Royal Society Insight Investment Science Book Prize, Susannah Cahalan talks to Adam Rutherford about her investigative journalism into the scientific mystery that is mental illness. Her book ‘The Great Pretender - The Undercover Mission that Changed our Understanding of Madness’ focuses on a fundamental experiment carried out in the 1970s by renowned Stanford University Professor of Psychology David Rosenhan. His famous study was published in Science under the title ‘Being Sane in Insane Places’ and describes using ‘pseudo-patients’ to test whether they would be spotted presenting at psychiatric institutions in the US. They weren’t! His findings proceeded to shape modern psychology and psychiatry. It has been a study that Susannah, has come to find rather mysterious, with elaborate descriptions that don’t always seem to add up. Mental illness and applied neuroscience remain tricky disciplines to navigate, but Susannah has had personal experience with her own misdiagnosis of schizophrenia when she has an autoimmune brain disease.COVID does funny things to your sense of smell: Adam got a heightened sense of smell, producer Fi totally lost her sense of smell, and Inside Science reporter, Geoff Marsh – well… his sense of smell just got weird. To find out why, Geoff called in Professors Mathew Cobb, an expert on smell at the University of Manchester, and Tim Spector from Kings College London whose symptom tracker app was instrumental in getting changes to sense of smell on the symptom list for COVID.Presenter – Adam RutherfordProducers– Fiona Roberts and Andrew Luck-BakerProduced in collaboration with the Open University

From the very start of the COVID pandemic, test and trace has been the mantra. But here in the UK it was started, then abandoned as the number of cases rose too high to manage. It’s now been reintroduced and we’re all being encouraged to download the ‘NHS COVID-19’ phone app which can detect whether you’ve been near an infected person using Bluetooth technology. How have other countries around the world been managing to find, test, trace, isolate and support (FTTIS) their COVID patients? And what lessons can we learn from them? Professor Michael Hopkins at the Science Policy Research Unit (SPRU), University of Sussex Business School is part of an international team of experts in science policy, social science, medicine, epidemiology and global health that has analysed and compared national testing systems in 6 countries: Spain, South Korea, South Africa, Ireland, Germany and us, in June, July and August. Michael Hopkins told Marnie Chesterton that we all have something to learn.Over the last few weeks, we’ve been stealing a glimpse into this year’s shortlisted contenders for the annual Royal Society’s Insight Investment Science Book Prize. Linda Scott is an Emeritus Professor from the University of Oxford and a consultant to the World Bank Group on gender economics. Her book, The ‘Double X Economy - The Epic Potential of Empowering Women ’ analyses the economics of gender inequality and the hidden economics which is foundational to the more recognised and acknowledged global economics, that is, the work - much of it unpaid - done by women. Presenter – Adam RutherfordProducer – Fiona RobertsProduced in collaboration with the Open University