BBC Inside Science

BBC Radio 4
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Feb 25, 2021 • 30min

Good COP Bad COP, Shotgun Lead Persistence, and Featherdown Adaptation

On Thursday, The UN Environmental Programme published a report called Making Peace With Nature. It attempts to synthesise vast amounts of scientific knowledge and communicate “how climate change, biodiversity loss and pollution can be tackled jointly within the framework of the Sustainable Development Goals”. But it also offers clear and digestible messages that governments, institutions, businesses and individuals can act upon. Concluding BBC Inside Science’s month-long look at some of the challenges ahead of COP26 in Glasgow later this year, and its sister biodiversity meeting in China, Vic speaks with the report’s co-lead Prof Sir Robert Watson FRS and the Tyndall Centre’s Prof Rachel Warren, also a contributing author. Can all the ills of the natural world really be tackled at once?Game-shooting, for sport and food, has traditionally used the toxic metal lead for ammunition. In other parts of the world its use has been banned for the dangers to the human food chain and to the pollution in natural environments, and even deaths of wildfowl from poisoning. But not so in the UK. A year ago, as reported on Inside Science at the time, the shooting community announced a voluntary five year transition period to alternative shot materials. But researchers including profs Rhys Green and Debbie Pain from Cambridge University have discovered that a year on, little seems to have changed. Gathering game sold for food across the UK, they found that all but one bird in their sample of 180 contained lead shot. Meanwhile, up in the Himalayas, Smithsonian scientist Dr Sahas Barva was enjoying the scenery on a cold day off in 2014 when he saw and heard a tiny Goldcrest, thriving in temperatures of -10C. Wondering how such a tiny thing could keep its body insulated, he decided to investigate feathers, and utilizing the huge numbers of specimens in the Smithsonian’s collection he found some striking commonalities in the thermal properties and adaptations of birds everywhere. The higher up they live, the fluffier their coats.Presented by Victoria GillProduced by Alex MansfieldMade in association with The Open University.
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Feb 18, 2021 • 50min

Nasa's Perseverance - will it pay off? And spotting likely hosts for future pandemics.

On Thursday 18th Feb 2020 Nasa’s Perseverance Rover is due to touch down – gently and accurately – in the Jezero crater on Mars. Using similar nail-biting Sky Crane technology as its predecessor Curiosity, if successful it will amongst many other things attempt to fly the first helicopter in the thin Martian atmosphere, and leave small parcels of interesting samples for future missions to collect and return to earth. Unlike previous Martian landings of course, there are no mass-landing parties to be held because of Covid. So Vic Gill invites you to join her and current Curiosity and future Rosalind Franklin (ESA’s 2023 Rover) team scientists in nervously awaiting the signal of success.Dr Susanne Schwenzer was so tense during Curiosity’s final approach in 2012 that she managed to draw blood from her own hand from clutching her mobile phone too hard. BBC Inside Science expects nothing less this time round. Dr Peter Fawdon has been part of the team seand examining the landing site for ESA’s Martian lander and Rover, currently slated to launch in 2022. The project has had a complicated history, having been delayed several times. But with so much at stake, it’s worth getting right. Meanwhile, at Liverpool University, computer scientist Dr Maya Wardeh and virologist Dr Marcus Blagrove have been collaborating to see if Machine Learning and AI can help predict which mammalian species are more likely to harbour the next big coronavirus. Pitting traits and genomes, species similarities, lifestyles and ecosystems of mammals and viruses, they highlight in a paper published in Nature Communications some of the potentially most potent combinations where different coronaviruses could meet and spawn a new breakout. Not just looking for the more quotidian viral mutations the world is increasingly and unfortunately aware of, they have been looking instead for those species where something called homologous recombination between two different viruses, producing a third completely novel type, may occur. It turns out there are many possibilities beyond just bats, which are highly suspected of being the crucible in which SARS-CoV2 was smelted. To spot whatever comes next we should keep an eye on camels, rabbits, palm civets and even hedgehogs, according to the algorithm.Presented by Victoria Gill Produced by Alex MansfieldMade in Association with the Open University.
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Feb 11, 2021 • 41min

Meeting Mars, Melting Ice, Ozone on the Mend Again, and A Sea Cacophany

Victoria Gill and guests discuss the signs and symptoms of melting ice and anthropogenic climate warming, illicit CFC production and the racket we make in the seas. As two robotic missions from UAE and China arrive at Mars , and a third from NASA arrives next week, UK astronaut Tim Peake talks of the international collaboration in Mars research that is to come. And continuing BBC Inside Science's look at some of the issues facing COP26 delegates to Glasgow this autumn, Victoria is joined by cryosphere scientist Dr Anna Hogg,Anna studies – sometimes from space - how polar and Greenland ice sheets are melting and shifting as our climate warms. But those giant volumes of ice and concomitant rising sea levels might not be the only threat to people’s lives. It may be that the recent deadly flash flood in India was a result of a swiftly melting Himalayan glacier.The Montreal treaty - prohibiting the production of CFCs to allow the man-made polar hole in the Ozone layer identified back in the 1980s to repair - has long been cited as the classic example of an effective international agreement to protect earth's environment. But just a few years ago in 2018 Luke Western and colleagues identified not just that CFC production was suddenly and unexpectedly rising, but that it was mainly emanating from an area in eastern China. It was speculated then that their use in foams for buildings was happening illicitly on a large scale. This week, they happily announce that those emissions seem to have ceased, and that the target of a healthy ozone layer is back on track.The oceans are, since man first took to the waves, a noisy place. In a comprehensive paper published last week in the journal Science Carlos Duarte and colleagues describe how huge an impact the many anthropogenic noises that echo for miles across the sea beds have on virtually all aquatic life. He argues that it is one stressor, rather like CFCs, that we could and should take swift and effective action to address, that the time for that is ripe, and that doing so will see a swift rebound in many aquatic ecosystems. Humans are not naturally adapted to hear the noise underwater, but to illustrate the point, co-author digital artist Jana Winderen has made an acoustic demonstration for your benefit, of quite how noisy neighbours we areAlso, for listeners on BBC Sounds, the BBC's Roland Pease gives an update on where and how scientists think the covid-19 epidemic began, after a WHO team of scientists report on their recent mission to Wuhan and the infamous market. As Roland and WHO delegate Peter Daszak surmise, we still don't quite know, but it wasn't in a lab.Presented by Victoria Gill Produced by Alex MansfieldMade in Association with The Open University.
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Feb 4, 2021 • 42min

Putting a number on biodiversity

Ahead of the COP summit in Glasgow at the end of the year, this week an important study was published that attempts to enumerate the value of biodiversity in the economics of humankind. Prof Sir Partha Dasgupta's review makes it clear how essential and yet vulnerable it is.Trees play a large part in the biosystems of the planet, and replanting them is often touted as a solution to many of the carbon challeneges of the next century. But a paper and forthcoming conference hosted by Kew points out just how carefully reforestation - let alone afforestation - must be conducted.Kew tree expert Kate Hardwick tells Victoria about their 10 golden rules of planting trees.In a forest in Borneo, trees have been planted that will extract the high levels of Nickel from the local soil. It is hoped that the biomass from the trees can then be used to harvest the nickel. It is an attempt to commercialize successfully the dreams of "phytomining" - finding specific crops or traits in plants that can act to "hyperaccumulate" minerals and metals from soils. BBC Inside Science's Harrison Lewis reports how, after some intrepid botany, the idea might just now be bearing heavy fruit.But finding the plants that do some of what you want them to does not mean they should be planted just anywhere. Lulu Zhang from United Nations University in Dresden, Germany tells Victoria about the Chinese experience of a few decades ago when the Black Lotus tree seemed to be just the ticket for newly foresting huge areas of China to stabilize and neutralize soils. Unfortunately, nobody realized how thirsty the monocultured forest would be, and the thirsty trees deprived the area of much of the rainwater from humans and agriculture.Meanwhile this week scientists have published work looking at how even the noise from traffic on the roads can disrupt animal behaviour. Chris Templeton of Pacific University in Oregon has been studying how some bird's cognititve abilities can be affected. And Adam Bent describes work at Anglia Ruskin University into how crickets' mating choices can be adversely affected by recordings of the A14 near Cambridge.Presented by Victoria Gill Produced by Alex MansfieldMade in association with The Open University
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Jan 28, 2021 • 36min

Next Gen Covid Vaccines; Man's Oldest Bestest Friend; Bilingual Brain Development

A year after the first SARS-Cov2 sequences were received in the vaccine labs, Dr Alex Lathbridge and guests look into ongoing development and what next year's booster shots might be like. Prof Robin Shattock's team at Imperial College are still working on their vaccine technology - called 'Self Amplifying RNA' or saRNA. A little bit behind their well financed corporate colleagues, this week they announced that instead of pressing ahead with a phase III trial, they will instead look to developing possible boosters and alternative targets just in case more and more serious mutations happen. But as Prof Anna Blakney explains from her lab at University of British Columbia, the possibilities of saRNA don't stop with coronaviruses.Researchers in the journal PNAS report this week a new theory as to when and where dogs were first domesticated by humans, and suggest that they accompanied the first humans across the Bering straight into America. Inside Science's Geoff Marsh has a sniff around.And Dr Dean D'Souza from Anglia Ruskin University describes in Science Advances work he has done looking at certain kinds of development in children who grow up in bilingual households. His work suggests a slightly faster and keener observation of detailed changes in visual cues, and that this seems to be a trait that survives into adulthood. Presented by Alex LathbridgeProduced by Alex MansfieldMade in Association with The Open University
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Jan 21, 2021 • 31min

Vaccine Hesitancy and Ethnicity; The Joy of catnip; Lake Heatwaves

Reports this week talk of some BAME ethnic minorities being significantly less likely to take a covid vaccine if offered. Vittal Katikireddi and Tolullah Oni both sit on the SAGE ethnicity subgroup, and they discuss with Alex Lathbridge where the figures come from and quite what they might mean. Some of these same groups have suffered some of the worst outcomes from infection. Addressing any underlying problems that bely the figures will take a nuanced approach.Researchers in Japan and Liverpool have been investigating cat's prediliction for the herbs Catnip and Silver Vine. It turns out that there may well be a deep evolutionary reason they have evolved to love rubbing it in their fur so much: a key ingredient is a good mosquito repellent. As Professors Masao Miyazaki and Jane Hurst describe. It could help keep the mozzies away but you might end up being tailed by cats.And researcher Iestyn Woolway of the European Space Agency Climate Group, at Didcot UK, describes his work modelling the world's lakes' reaction to a warming climate over coming decades. It's not very comforting, with increased duration and intensity of what he calls "Lake Heatwaves".Presented by Alex Lathbridge Produced by Alex MansfieldMade in associataion with the Open University.Note: This podcast has been edited since the original broadcast to prevent any possible inference that the Tuskegee syphilis study involved the deliberate infection of subjects. In the Tuskegee study, African American patients who were already infected with syphilis had diagnosis and treatment deliberately withheld from them in order to observe the progression of the lethal disease over several decades (even after a perfectly simple treatment - penicillin - became available).
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Jan 14, 2021 • 33min

UK Science post Brexit; GMOs vs Gene Editing regulation; Identical Twins That Aren't Indentical

In the new EU-UK deal, the UK is to be an associate member of the latest EU research funding round, known as Horizon Europe. Costing around £2bn to take part, what can UK scientists now do and what has changed? UKRI CEO Otteline Leyser and the Wellcome Trust EU specialist Beth Thompson discuss ways in which UK researchers are breathing a sigh of relief.Of all the ways the UK can now diverge from the EU, DEFRA is currently holding an open consultation on whether to tweak the current GMO regulations so as not to include CRISPR-style Genetic Editing. The EU is coincidentally looking at the same issue. John Innes Centre's Janneke Balk works on making strains of wheat that have a higher level of iron for nutritional fortification. Interim head of the Roslin Institute in Scotland Bruce Whitelaw thinks developing disease resistance in farm animals is a potentially profitable area. Both agree the GMO regulations should be more tightly specified to bring clarity and opportunity for innovation. In Iceland, Kari Stefansson's company Decode Genetics analyze the genetic codes of most of the population of Iceland. This has allowed them to look at the parents, siblings, and offspring of identical twins, and identify how early genetic differences between them develop. And it's very early indeed. Given that identical twins studies are so often used to address issues surrounding the so-called Nature-vs-Nurture debate, the findings, published in the Journal Nature, are striking. Presenter by Marnie Chesterton Produced by Alex MansfieldMade in association with the Open University.
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Jan 7, 2021 • 39min

Vaccine Dosing and Biodiversity Soundscape Monitoring

After the decision by the UK government last week to change the spacing between dosings of vaccine from the recommended 3 weeks to 12 weeks, immunologists around the world have been discussing with some urgency the wisdom of such a move. The FDA and the WHO are deeply sceptical, and the manufacturers have distanced themselves to some extent, by cautioning not to deviate from the regime tested in last year's phase III trials. The thinking behind the move is to get more people injected with a single dose in a shorter time, and that the longer wait for the second shot is worth the risk, if it means more people receive some level of protection in the short term.Clinical Epidemiologist Dr Deepthi Gurdasani and Immunoligist Prof Danny Altmann of Imperial College describe to Marnie how evidence, experience and hunch are combining in the face of the covid crisis, and quite what we know, what we don't and what we could, about this nationwide experiment. Increasingly, ecologists wanting to monitor remote areas are relying on such things as solar powered audio recorders to measure biodiversity in the sounds of the wild. But how to scrutinize years and years worth of 24 hour, multi-site recordings? Sarab Sethi and colleagues have not only been leaving solar-powered Raspberry Pi recorders out in the jungles of Borneo, they've been using machine learning techniques to look out for species and biodiversity changes from afar. You can listen to some of the Borneo work at the SAFE acoustic website (link on BBC page below).Presented by Marnie ChestertonProduced by Alex MansfieldMade in collaboration with the Open University.
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Dec 31, 2020 • 39min

Brian Cox and Alice Roberts on a decade of extraordinary science

As a new decade ticks over, Dr Adam Rutherford, Professor Alice Roberts and Professor Brian Cox look back on a decade of science that has transformed perceptions of our medicine, our history and our universe.From advances in genetics that have brought personalized medicine to reality, and revealed the ghosts of ancestral human species never before identified, to quantum computing lessons that hint at the nature of existence and causation throughout the universe, it has been an interesting time. New observational technologies have revealed fresh windows in time and space. And all of it has been reported by BBC Inside Science. But what of the next decade? Programme may contain traces of informed speculation, but (almost) no references to Covid.Presented by Adam Rutherford Produced by Melanie BrownMade in association with The Open University.
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Dec 24, 2020 • 32min

Space Rocks, Aquatic Dinosaurs and Global Temperatures; 2020 science reviewed

Nobody could have failed to notice the one story dominating the science news this year - but what about the discoveries that have been overshadowed in 2020? This week, Dr Adam Rutherford eschews all mentions of the pandemic as he invites dinosaur researcher Dr Susie Maidment, climate scientist Dr Tamsin Edwards and astrophysicist Dr Emma Chapman to share their science highlights of the year. We journey to the moon and beyond to discuss the many missions that have been blasting and grabbing bits of space rock to bring back to earth and tackle the ongoing debate about whether signs of life have been found on Venus. Back down on earth, this year could be one of, if not the, hottest years on record, with particularly high temperatures in the Arctic Circle. What might a warming world mean for ice-shelf collapse in Antarctica and how are governments responding? We discuss Joe Biden’s presidency, UK carbon emissions and what China’s recent announcements of net zero by 2060 might mean for the future of the planet. And despite limitations on travel this past year, exciting discoveries in the dinosaur world have nonetheless continued with what is believed to be the first aquatic dinosaur. The detection of soft shell eggs is also changing understandings of how dinosaurs reared their offspring.And if that wasn’t enough, Dr Adam Rutherford challenges our experts to predict what big science stories might lie on the horizon in 2021.

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