
Breaking Health
The Breaking Health Podcast features the innovators, investors and entrepreneurs who are building the technology and tools to break down and build up the country’s ailing health care system. With seasoned health care investor Steve Krupa, CEO of the Psilos Group, as host, Breaking Health delivers the earliest insights on the ongoing Digital Health Revolution.
Latest episodes

Jun 17, 2025 • 28min
Episode: 173 - Matt Bettonville on Oncological Research and Drug Discovery Investment
In this episode of Breaking Health, host Steve Krupa speaks with Matt Bettonville, investor at Yosemite, about the state of oncology research and his hunt for investments in discovery and treatment tools. Bettonville delves into the key to cancer treatment, where deals are flowing towards in the market, and how the AI revolution is helping with drug discovery and cancer treatment breakthroughs. He also discusses the complications (and frustrations) of making treatments affordable, finding new targets in primary cancers most frequently seen in the population, and the importance of early detection. Links from this episode: HealthEdgeYosemite

May 13, 2025 • 44min
Episode: 172 - Solving Prior Authorization from Both Sides with Jeremy Friese
In this episode of Breaking Health, guest host Payal Agrawal Divakaran, partner at .406 Ventures, speaks with Jeremy Friese, CEO of Humata Health, about prior authorization and how Humata is helping from “both sides of the fax machine.” Friese also discusses his thoughts on the future of AI adoption, how the regulatory landscape looks, and more. He also shares what the transition between physician to entrepreneur was like, what it’s like to found and grow companies, and how to select the right VC partners. Links from this episode: HealthEdge .406 Ventures Humata Health

Feb 18, 2025 • 39min
Episode: 171 - Heart Health Month: Jeffrey Wessler on Providing Virtual Cardiovascular Healthcare
Jeffrey Wessler, MD, MPhil, is the CEO of Heartbeat Health, a company reshaping virtual cardiology. He discusses the transformative role of telemedicine in cardiovascular care and how it effectively addresses skepticism around remote healthcare. Wessler emphasizes the importance of hybrid care models and innovations in technology for improving patient outcomes. He also shares insights on being a physician-entrepreneur, navigating healthcare disparities, and the impact of GLP-1 medications on cardiac health while advocating for awareness during Heart Health Month.

8 snips
Dec 17, 2024 • 33min
Episode: 170 - Kate Condliffe on Accessible Maternity Care and the Future of Women’s Health
Kate Condliffe, CEO and co-founder of Diana Health, shares her mission to revolutionize maternity care. She discusses the importance of partnerships with hospitals to enhance individualized care for women. Condliffe emphasizes the necessity of innovative care models and the integration of various services to meet the evolving needs of expectant mothers. The conversation also tackles how recent political changes influence women's health and highlights the vital roles of doulas and comprehensive care models in improving maternal experiences.

Oct 22, 2024 • 37min
Episode: 169 - Kristina Saffran Discusses Accessible Eating Disorder Treatments, Choosing Cofounders, More
In this special video episode of Breaking Health / In this episode of Breaking Health, guest host Payal Agrawal Divakaran, partner at .406 Ventures, speaks with Kristina Saffran, cofounder and CEO of Equip about providing accessible eating disorder treatment for patients everywhere. Saffran shares the origins of Equip, busts some myths surrounding eating disorders, and explains how her company pays for health plans. She also discusses the importance of working with the right cofounders, picking the right VC partners, navigating rough patches, fundraising, and more. Divakaran and Saffran also share their thoughts on contemporary topics and trends in the industry in a lightning round. Links from this episode: HealthEdge .406 VenturesEquip

Jun 4, 2024 • 37min
Episode: 168 - Jon Maschmeyer on Private Equity and Investments in the Healthcare Space
In this episode of Breaking Health, host Steve Krupa speaks with Jon Maschmeyer, partner at Permira. Maschmeyer discusses what it’s like working with executives and what they learn from him about investments, what sector has the most activity today in terms of deal flow, what attributes he finds exciting when considering a deal, and the key to working with private equity as a management team. He also shares his thoughts on how lower rates for high-volume drugs affect other countries, specialty pharma, and how healthcare has evolved in the past 20 years.

Feb 20, 2024 • 50min
Episode: 167 - Generative AI in Healthcare: Hype or Hope?
Leaders in the AI industry discuss the progress and hype around generative AI in healthcare, including challenges such as regulatory frameworks and liability cases. Topics also cover the role of AI in healthcare strategy, leveraging generative AI for staffing and value-based care, driving value with AI, strategic partnerships for AI operationalization, the evolution of the Chief AI Officer in healthcare, regulatory aspects of generative AI, and evaluating bias in AI for nurse assistance.

Nov 21, 2023 • 29min
Episode: 166 - Andrew Adams On How to Find the Right Opportunities to Invest
When is the best time to make an investment? In the healthcare industry, this can be tricky to determine. In this episode of Breaking Health, host Steve Krupa speaks with Andrew Adams, Co-Founder and Managing Partner at Oak HC/FT, about organizing capital into the right companies, where the healthcare industry is going in terms of deployment of technology, and the state of the market today. With a broad and impressive portfolio, Adams provides valuable insight and techniques on finding the right opportunities to invest, as well as value-based hotspots and new ventures that Oak HC/FT is conducting. Links from this episode: HealthEdge Oak HC/FT

Oct 24, 2023 • 27min
Episode: 165 - Kyle Kiser Talks About Providing Patients Access To Medication Information And “Real Time Benefits”
When patients receive prescriptions, many find themselves at a loss over the lack of information on the medications’ clinical uses, costs, and more. In this episode of Breaking Health, host Steve Krupa speaks with Kyle Kiser, CEO of Arrive Health, about giving patients the ability to access information on medications to help them make better healthcare decisions. Kiser also delves into what real time benefits are, the company mantra “Lucy up,” and how Arrive Health calculates and provides valuable data to their customers, such as general savings. He also talks about his journey from being a healthcare insurance wholesaler to starting Arrive Health, as well as tips for aspiring entrepreneurs on patience and perseverance. Links from this episode: HealthEdge Arrive Health

Jul 18, 2023 • 27min
Episode: 164 - Navigating Healthcare Rates with Price Transparency
From sports goods salesman and stand-up comedian to co-founder and CEO of a software company, Chris Severn is helping patients by providing price transparency in healthcare through an easy-to-use platform. In this episode of Breaking Health, host Steve Krupa speaks with Severn about how he got the idea for a service that provided patients with upfront quotes, the value of such price transparency, and how to compare plans to help patients discern the best rates. Severn also shares his perspectives on new laws’ impact on the healthcare industry and the potential future of a competitive market for medical procedures. Links from this episode: HealthEdgeTurquoise Health