The Effective Statistician - in association with PSI

Alexander Schacht and Benjamin Piske, biometricians, statisticians and leaders in the pharma industry
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Nov 28, 2023 • 29min

Be Aware About the Stories You Tell Yourself!

Interview with Mirjam Sandlos, an exploration of belief systems and strategies for personal and professional growth. Topics include: concept of 'Glaubenssatz', power of thoughts on actions and outcomes, breaking limiting beliefs, impact on career, and the importance of embracing a growth mindset.
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Nov 23, 2023 • 18min

Why and How to Set Goals for You and Your Team

Importance of clear long-term vision and goals in personal and professional life; breaking down goals for increased trust and influence; setting visible and meaningful goals for alignment and action; identifying key capabilities and setting achievable goals; setting challenging and motivating goals
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Nov 20, 2023 • 57min

Building an R community - Learnings from AZ

Learn about the trajectory of R in the industry and the growth of AstraZeneca's R community. Discover the activities that contributed to its success, metrics for measuring its impact, and the personal journey of Guillaume Desachy in building the community. Explore the dynamics of collaboration among R enthusiasts at AstraZeneca and gain valuable learnings from their experiences.
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Nov 16, 2023 • 18min

What is Strategy

In this episode, Alexander Schacht discusses the pitfalls of bad strategy and the elements of a good strategy. He shares strategic insights from historical examples and emphasizes the importance of clear diagnosis, guiding principles, and tactical planning. The episode also explores the significance of strategy in decision-making, personal growth, and business success. It further highlights the power of podcasting as a tool for strategic thinking and collaboration.
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Nov 13, 2023 • 45min

From Ethics Guidelines to Implementing Ethical Statistics

Perspective on ethics in statistics and the importance of determining good behavior. Creating awareness and understanding through various means. Building trust by demonstrating care, competence, and character. Advocating for societal and environmental implications. Emphasizing algorithmic thinking and evidence-based decision-making. Highlighting the need for organizational change and effective collaboration. The journey toward ethical statistics is a shared responsibility with far-reaching impacts.
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Nov 9, 2023 • 18min

Sketching Your Career and Creating a Strategy

The speaker emphasizes the significance of data visualization and shares their own motivation to enhance their skills. They discuss the importance of having a long-term vision, setting bigger goals, and finding areas of passion. They highlight the need to devise a strategy, market oneself, and develop technical skills. Building skills, investing in leadership, and effective goal achievement are also explored.
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Nov 6, 2023 • 26min

Defining Clinical Trial Estimands: A Practical Guide for Study Teams with Examples including Regulatory Buy-in

Interview with Elena Polverejan The Genesis of Estimands: A conversation in 2017 that led to the creation of the Estimands Framework, a shared language to simplify complexity in clinical trials. A Closer Look at Depression Studies: Me and Elena strategically chose depression as their focus for research due to its unique challenges, including efficacy, maintenance, intercurrent events, and time-to-event endpoints. The Practical Guide: A collaborative effort between stakeholders has produced a practical guide to help study teams better understand and utilize the Estimands process for clinical trial design. Regulators on Board: Getting the support and validation of regulatory bodies was an essential factor in the success of the Estimands Framework. A Blueprint for Progress: The Estimands Framework, developed by me and Elena, enhances the pharmaceutical industry by providing a path towards greater precision, clarity, and collaboration in clinical trials. Listen to this episode now and share this with your friends and colleagues!
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Oct 30, 2023 • 29min

Cross-Over Studies: When Do They Offer a Great Advantage?

This podcast discusses the advantages of crossover studies in scientific research. It covers topics like randomization, order effects, and carryover effects. The challenges of conducting studies with multiple treatments are also explored, along with a case study in the allergy field. The importance of controlled environmental chambers for allergen exposure is highlighted. Overall, the podcast emphasizes the significance of understanding crossover designs in research and the potential they hold for innovative discoveries.
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Oct 23, 2023 • 39min

Do You Still Negotiate About Numbers of Tables?

Understanding negotiation in the context of table production costs, reducing and restructuring tables, active listening in negotiation, investing in leadership skills, a leadership training program, modular table production concept
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Oct 16, 2023 • 38min

Risk Mitigation for Statisticians

Jess Thompson, an expert in risk management in clinical trials, discusses the importance of continuous risk assessment, collaborative risk identification, and the role of assumptions. She also emphasizes the need for collaboration and input from team members when assessing risks, as well as contingency planning and risk reporting for successful risk management.

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