The Effective Statistician - in association with PSI

Benjamin, an expert in statistical trends, joins Alexander to discuss the rise of large language models, transparency in data and privacy concerns, virtual and augmented reality in work environments, collaboration through specialized marketplaces, open source programming and collaboration, and payer involvement in drug development. This thought-provoking episode explores the dynamic trends shaping the statistical landscape and emphasizes the importance of staying informed and embracing new approaches in effective statistical work in drug development.

In this podcast, the speaker discusses the importance of networking, training, and engaging in impactful projects for creating opportunities in a statistical career. They highlight the role of external collaborations, conferences, and special interest groups for expanding networks. The speaker also emphasizes the significance of preparation, confidence-building, and investing in leadership skills. Overall, they encourage statisticians to actively create opportunities and be proactive in their career growth.

Artemis Koukounari, an expert in observational studies and Estimand frameworks, discusses the challenges and experiences of using Estimands in observational studies. Topics include enhancing controls with historical data, challenges with propensity score methods, importance of sensitivity analysis, and differences between clinical trials and observational studies

Interview with Mirjam Sandlos, an exploration of belief systems and strategies for personal and professional growth. Topics include: concept of 'Glaubenssatz', power of thoughts on actions and outcomes, breaking limiting beliefs, impact on career, and the importance of embracing a growth mindset.

Importance of clear long-term vision and goals in personal and professional life; breaking down goals for increased trust and influence; setting visible and meaningful goals for alignment and action; identifying key capabilities and setting achievable goals; setting challenging and motivating goals

Learn about the trajectory of R in the industry and the growth of AstraZeneca's R community. Discover the activities that contributed to its success, metrics for measuring its impact, and the personal journey of Guillaume Desachy in building the community. Explore the dynamics of collaboration among R enthusiasts at AstraZeneca and gain valuable learnings from their experiences.

In this episode, Alexander Schacht discusses the pitfalls of bad strategy and the elements of a good strategy. He shares strategic insights from historical examples and emphasizes the importance of clear diagnosis, guiding principles, and tactical planning. The episode also explores the significance of strategy in decision-making, personal growth, and business success. It further highlights the power of podcasting as a tool for strategic thinking and collaboration.

Perspective on ethics in statistics and the importance of determining good behavior. Creating awareness and understanding through various means. Building trust by demonstrating care, competence, and character. Advocating for societal and environmental implications. Emphasizing algorithmic thinking and evidence-based decision-making. Highlighting the need for organizational change and effective collaboration. The journey toward ethical statistics is a shared responsibility with far-reaching impacts.

The speaker emphasizes the significance of data visualization and shares their own motivation to enhance their skills. They discuss the importance of having a long-term vision, setting bigger goals, and finding areas of passion. They highlight the need to devise a strategy, market oneself, and develop technical skills. Building skills, investing in leadership, and effective goal achievement are also explored.

Interview with Elena Polverejan The Genesis of Estimands: A conversation in 2017 that led to the creation of the Estimands Framework, a shared language to simplify complexity in clinical trials. A Closer Look at Depression Studies: Me and Elena strategically chose depression as their focus for research due to its unique challenges, including efficacy, maintenance, intercurrent events, and time-to-event endpoints. The Practical Guide: A collaborative effort between stakeholders has produced a practical guide to help study teams better understand and utilize the Estimands process for clinical trial design. Regulators on Board: Getting the support and validation of regulatory bodies was an essential factor in the success of the Estimands Framework. A Blueprint for Progress: The Estimands Framework, developed by me and Elena, enhances the pharmaceutical industry by providing a path towards greater precision, clarity, and collaboration in clinical trials. Listen to this episode now and share this with your friends and colleagues!