
The DeSci Podcast
Rethinking Science - Let's talk to the leaders of the decentralized science industry about the future of biotech. Brought to you by www.molecule.to
Want to join the stage? Apply as a speaker here: podcast@molecule.to
Latest episodes

May 9, 2023 • 38min
CryoDAO - Advancing Cryopreservation Research using Web3
Welcome to another episode of the DeSci Podcast. In this episode, we were joined by Dr. Emil Kendziorra and Kai Micah Mills, co-initiators of CryoDAO, a decentralized community dedicated to advancing cryopreservation research.
In this podcast, we discuss the field of cryonics, including its origins and how it has evolved over the years. Dr. Emil and Mills also explain how cryopreservation works, the underexploited areas in the field of Cryonics, and how it should be Improved.
We also address some of the common misconceptions about cryopreservation and recommended resources for those interested in learning more about Cryonics.
Finally, our guests share their thoughts on what the future of cryonics might hold and discuss some of the most contentious topics in the field.
Feel free to navigate through any of the topics discussed in the Podcast using the timestamps below.
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⭐ Timestamps:
0:00 Intro
1:07 Brief overview of the field of Cryonics
3:45 Origin and Evolution of Cryonics
5:51 How does Cryopreservation work?
7:00 What drove your interest in Cryonics?
10:13 Underexploited areas in Cryonics.
11:36 What is the strongest argument against Cryonics?
13:35 How public perception of Cryonics has developed over the years.
16:29 Why pets instead of humans?
18:08 Why did you become a DAO?
22:43 Areas of overlap in cryonics.
25:32 The future of Cryonics.
28:37 What is the most contentious topic in Cryonics?
30:44 Common misconceptions about cryopreservation
33:27 Resources for people interested in the field of Cryonics.
35:39 How to get involved.
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Special thanks to:
Lea Degen (host): https://twitter.com/lealeata
Kai Micah Mills: https://twitter.com/kaimicahmills
Dr. Emil Kendziorra: https://www.linkedin.com/in/emilkendziorra/
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Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

Apr 12, 2023 • 56min
AthenaDAO: Reimagining and Empowering Women's Health
Welcome to another episode of the DeSci Podcast. In this one, we had the pleasure of talking with Laura Minquini, who is leading AthenaDAO, a community-led movement that is improving female reproductive health through the identification, financing, and support of research projects that are working on its potential cures. We talked about Laura's story, the global panorama of the problem that she is solving, and the journey and projections of the organization that she founded and bio.xyz helped shape.
Navigate through the topics discussed in this podcast using the timestamps below.
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⭐ Timestamps:
0:55 Intro
1:50 About Laura Minquini
8:36 About AthenaDAO
11:21 Research in Female Reproductive Health Overview
15:49 AthenaDAO structure and projects in its pipeline
23:26 AthenaDAO's first IP-NFT
26:10 Aging & Fertility
33:41 Why scientists choose to join AthenaDAO
39:44 Bio.xyz acceleration journey
43:23 Strategies to raise awareness
47:35 How to Contribute to AthenaDAO
51:34 What would happen if AthenaDAO succeeds
54:18 Outro
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If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.
If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to
Special thanks to:
Aastha (host): https://twitter.com/aasthajs
Laura Minquini: https://twitter.com/LauraMinquini
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Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

Apr 3, 2023 • 52min
ValleyDAO on Building a Sustainable Future with Synthetic Biology
Welcome to another episode of the DeSci Podcast. In this episode, we were joined by ValleyDAO's Co-founder, Albert Anis, and Communications Lead, Morgan Richards.
In this video, Albert Anis and Morgan Richards provide a deep dive into the interesting field of Synthetic Biology, and the significant role that ValleyDAO plays in driving innovation in this area.
We also explored the traditional funding model for Synthetic Biology and the difficulties it presents for researchers. They then emphasize the need for a new, decentralized approach to funding and the importance of collaboration in the research field.
Albert and Morgan also go on to discuss the challenges of building in DeSci, and ValleyDAO's unique approach to incubating new projects, which involves providing funding, expertise, and a supportive community for researchers.
Feel free to navigate through any of the topics discussed in the Podcast using the timestamps below.
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⭐ Timestamps:
0:40 Intro
1:18 Albert Anis’ Background
6:26 What drove your interest in Synthetic Biology?
11:19 About Valley DAO
15:33 What is Synthetic Biology?
19:58 The problem of the traditional model of funding Synthetic Biology.
24:42 What areas are ValleyDAO focused on?
31:26 ValleyDAO’s process of incubating other projects
36:23 Value of Web 3 tools to Synthetic Bio Researchers
41:20 Challenges of building in DeSci
45:50 Areas of Overlap in ValleyDAO
47:40 ValleyDAO upcoming projects
50:14 How to get involved
50:41 Outro
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Special thanks to:
Alex LaBossiere (Host): https://twitter.com/adlabossiere
Albert Anis: https://twitter.com/thealbertanis
Morgan Richards: https://twitter.com/Mxltiplex
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Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

Mar 22, 2023 • 32min
HairDAO: A Community-Led Movement to End Hair Loss For Good
Welcome to another episode of the DeSci Podcast. In this episode, we had the pleasure of talking with Andrew Verbinnen and Andrew Bakst from HairDAO, the second BioDAO ever to mint an IP-NFT. Their mission is to turn hair loss into a problem of the past by funding assets that they believe will accelerate its cure. Throughout the conversation, we delve into a variety of fascinating topics related to hair loss.
We explore the bigger picture of this issue and highlight the crucial role of DeSci in expediting the discovery of solutions. And our guests also provide valuable insights gained from their experience in building in this ecosystem, shining a light on the HairDAO community, as well as the exciting projects that they have funded and upcoming initiatives.
Navigate through the topics discussed in this podcast using the timestamps below.
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⭐ Timestamps:
0:23 Intro
01:08 About Andrew Verbinnen
03:01 About Andrew Bakst
04:11 Why HairDAO
05:50 Hair Loss Research & Solutions State
10:17 Hair Loss Multiphase Problem
11:57 HairDAO Community
15:05 HairDAO’s First IP-NFT
16:53 Study of Prof. Ralf Paus
19:41 Crypto & Global Cooperation
20:37 First Patient Database in DeSci
22:43 Importance of IP-NFTs
25:02 Learnings from Building a BioDAO
27:01 HairDAO Vision
27:58 HairDAO Upcoming Initatives
31:11 Outro
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If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to
Special thanks to:
Alex LaBossiere (Host): https://twitter.com/adlabossiere
Andrew Verbinnen: https://twitter.com/VerbinnenAndrew
Andrew Bakst: https://twitter.com/andrew_bakst
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Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

Mar 15, 2023 • 53min
IP-NFT Technical Deep Dive: Token Standards, Decentralized Storage and UX
Welcome to this episode of the DeSci Podcast, where we dive deep into the technology behind IP-NFTs and explore the possibilities of decentralized data storage.
In this episode, Stefan Adolf, a senior web3 engineer at Molecule, and Benji Leibowitz, a former biotech venture capitalist and now a product manager at Molecule, discuss the modularity of IP-NFTs, the advantages of ERC721, 1155, and 3525 token standards.
We also discuss the benefits of Arweave and IPFS for metadata and storage, Lit Protocol and unlocking data, custodial wallets and MPC providers, the SDK for developers, and the possibilities of permissionless minting and open source strategies with v2 and v3 of the IP-NFT.
We hope you can learn a lot about the amazing possibilities of the decentralized tech stack and how you can build with IP-NFTs with this episode and feel free to use the timestamps below to navigate through the episode.
Navigate through the topics discussed in this podcast using the timestamps below.
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Timestamps:
00:00 - 01:42 Intro
01:42 - 04:30 What is the IP-NFT and who should use it?
04:30 - 08:40 Token Advantages (ERC721, 1155, and 3525)
08:40 - 11:18 IP-NFT V2 (Mint-passes and Reservations)
11:18 - 12:40 Who is the ideal user for a min-pass?
12:40 - 17:24 Where is the metadata of an IP-NFT stored, and how is it structured?
17:24 - 25:19 Difference between web3 and web2 storage
25:19 - 29:21 Content gating with DAO tools
29:21 - 34:56 The role of Lit-Protocol within the IP-NFT
34:56 - 49:00 Frontend of the IP-NFTs and on web3 wallets
49:00 - 51:59 When can people start building on this technology (wen SDK?)
51:59 Outro
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If you want to watch the Podcast on YouTube, you can find all the important links below. And if you want to join us on the show as a speaker or have guest ideas; please mail us at podcast@molecule.to
linktr.ee/thedescipodcast
Special thanks to:
Heinrich Tessendorf (Host): https://twitter.com/Heintess_GM
Stefan Adolf: https://twitter.com/stadolf
Benji Leibowitz: https://twitter.com/benjileibo
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Let's connect:
Website: https://molecule.to/
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

Feb 7, 2023 • 1h 43min
Vera Gorbunova on Longevity, Aging Biology and DeSci (Decentralized Science)
Welcome to another episode of the DeSci Podcast. In this episode, Vera Gorbunova, endowed Professor of Biology at the University of Rochester, co-director of the Rochester Aging Research Center, and co-founder of the new journal Aging Biology, run by scientists for scientists, shares with us a bit of her vast knowledge in the field of Longevity. She talked about the problems of the current scientific system, the partnership that her laboratory made with VitaDAO, and about the research that she is currently carrying out.
Navigate through the topics discussed in this podcast using the timestamps below.
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Timestamps:
0:42 Intro
2:53 Vera's Life Story & Background
7:44 Comparative Longevity Approach
14:12 Serendipitous Discoveries
15:34 DNA Repairing Fidelity & Epigenetics Reprogramming
24:46 Who are the heroes of Vera
27:09 What Vera strongly believes and that other people disagree
32:28 Possible Nobel Prize-winning work
35:14 Chromatin: Hallmark of Aging
39:25 HSC Stem Cells
45:20 Extracellular Matrix
50:12 VitaDAO x Vera’s Lab Partnership on Naked Mole Rats
1:00:26 Programmed vs Damage Theory of Aging
1:11:07 Issues between Scientific Journal Publishers, Editors and Reviewers
1:17:42 Potential of Decentralized Scientific Journals & Peer-review
1:32:18 Final Conclusions
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Special thanks to:
Sebastian Brunemeier (Host): https://twitter.com/sebastian_gero
Vera: https://www.linkedin.com/in/vera-gorbunova-64a97b46/
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Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

Jan 23, 2023 • 1h 14min
Michael P. Gibson on the 1517 Fund, Thiel Fellowship, and DeSci
Welcome to another episode of the DeSci Podcast. In this episode, Michael Gibson, co-founder and general partner of the 1517 fund, author of the new book ‘Paper Belt on Fire: How Renegade Investors Sparked a Revolt Against the University’ and one of the key people involved in launching the Thiel Fellowship in 2010 (where he helped Vitalik Buterin shape Ethereum), tells us about his vision of legacy institutions and how we can modernize them to encourage great global innovations once again.
You can already get his excellent book, discussed in the episode, on Amazon: https://www.amazon.com/Paper-Belt-Fire-Fight-Progress-ebook/dp/B099FZR4C3
Navigate through the topics discussed in this podcast using the timestamps below.
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⭐ Timestamps:
0:00 Intro
4:03 Book: ‘Paper Belt on Fire’
9:26 Michael’s Background
14:20 Innovation in America is slowing down
19:20 Why Michael drop out the Academia
24:08 ‘If the college degree were a drug they would not be passed by the FDA’
29:07 Cloud Universities
30:23 How to rebuild the Scientific Structure
38:59 VitaDAO and Alternative Funds
40:39 Accredited Investors
42:33 Investment Issues
44:26 Public Companies
46:00 New Disclosure Standard
49:03 Reproducibility Issues
53:42 Decentralized Science
1:07:00 How to motivate the next generation of great scientists
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If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to
Special thanks to:
Sebastian Brunemeier (Host): https://twitter.com/sebastian_gero
Michael: https://twitter.com/William_Blake
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Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

8 snips
Jan 15, 2023 • 48min
Vitalik Buterin on Decentralized Science, Aging, AI and Scientific Progress
Today we have a special one! In this episode, we have Vitalik Buterin as a guest, interviewed by Vincent Weisser.
They discuss the intersection of science and cryptocurrency, focusing on the concept of "decentralized science." Vitalik explains how decentralized technologies, such as cryptocurrency, can improve science and the institutions of science by allowing for more diverse funding and collaboration among people.
He also mentions specific tools, such as quadratic funding and decentralized autonomous organizations (DAOs), that can be used to fund and structure scientific projects. He also highlights his current project, "Balvi", which is focused on addressing the COVID-19 situation and is funded by cryptocurrency.
He also mentions the challenges of scaling up quickly and how this can be a good approach for established donors and talks about the use of technology such as DeSci and reputation systems to help solve the problem of determining who is trustworthy.
There is undoubtedly much more to be found in this episode and we hope you enjoy this conversation between Vitalik Buterin and Vincent Weisser. Make sure to skip between the timestamps below to find your favorite topics and learn more about the discussed topics through all the linked resources below.
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Some of the resources discussed.
- Vitaliks blog: https://vitalik.ca/
- Vitaliks twitter: https://twitter.com/vitalikButerin
- Decentralized Science Explainer https://ethereum.org/en/desci/
- Ending Aging book: https://en.wikipedia.org/wiki/Ending_Aging- Science DAOs like: http://vitadao.com/
- Some of the projects he supported https://cryptorelief.in/, https://impetusgrants.org/, https://www.sens.org/, https://arcinstitute.org/
- Balvi (Pandemic Prevention): https://twitter.com/VitalikButerin/status/1522017142320685057
- Quadratic Payments by Vitalik: https://vitalik.ca/general/2019/12/07/quadratic.html
- DeSoc Paper by Puja, Glen and Vitalik: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4105763
- Progress: https://www.theatlantic.com/science/archive/2019/07/we-need-new-science-progress/594946/
- Network States: https://vitalik.ca/general/2022/07/13/networkstates.html
- RadicalxChange: https://www.radicalxchange.org/
- The most important century https://www.cold-takes.com/most-important-century/
- Curveballs: pandemics, existential, risks from nuclear, ai, bio, wars
- Recommend reading: https://80000hours.org/
- DeSoc x DeSci by Puja: https://www.youtube.com/watch?v=MUzwSPmP4nY
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Timestamps:
00:00 - 00:37 Intro
00:37 - 06:36 Vitalik's definition of DeSci and what he is most excited about.
06:36 - 09:32 Improvements to retroactive or quadratic funding.
09:32 - 11:30 Vitalik on DeSoc in the context of science (Decentralized Society).
11:30 - 12:51 What to build at the intersection of DeSci and DeSoc?
12:51 - 13:46 Which areas of Science is Vitalik most excited about?
13:46 - 17:17 How the Shiba Inu tokens actually funded Covid research.
17:17 - 22:40 Why crypto is such an excellent funding method.
22:40 - 31:00 Which learnings did he incorporate into other projects like "Balvi"?
31:00 - 38:33 What's holding back scientific progress, and what is he most excited about?
38:33 - 44:37 The most important century ever? Vitalik on AI progress, Singularity, and existential risks.
44:37 - 46:47 What to build in the DeSci space?
46:47 - Vitalik's content recommendations in the science space.
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Let's connect:
Website: https://bit.ly/3d6nh2CTwitter:
https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

Jan 9, 2023 • 1h 10min
Decentralizing Data Science at LabDAO | Stanley Bishop (aka Science Stanley)
Welcome to another episode of the DeSci Podcast. In this episode, Stanley Bishop, AKA Science Stanley, data scientist and head of data science at LabDAO talks about AI, what it means to be a data scientist and how it intersects with decentralized approaches. We also talk about how this can be applied across individual health, collective health, the planets, genome sequencing and language models and what this could mean for the future of the organization and the future of work.
Stanley Bishop also talks about LabDAO’s collaboration with "Research to the People" in order to build an integrated and traditional data marketplace where treatments can be shared between physicians so they can compare notes and figure out the best clinical path for their patients which can be impactful for patients that might have rare or complex conditions, New Atlantis DAO and its mission to provide a solution for climate change and many more.
Navigate through the topics discussed in this podcast using the timestamps below.
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Timestamps:
0:00 Intro
1:38 What is a data scientist?
3:09 How has that led you to Lab DAO?
04:51 What does being a data scientist within a DeSci organization look like?
06:15 What projects are LabDAO working on right now?
09:18 LabDAO overall structure.
11:56 LabDAO's partnership with Research to the people.
16:17 The future of translational research.
18:36 What else is possible with DeSci?
23:42 New Atlantis DAO.
31:07 Recommendations for scientists transitioning into Web 3.
34:09 Collaboration with TalentDAO.
42:13 Other use cases of TalentDAO.
46:16 What AI trend do you expect to gain traction in the future?
50:39 Remunerating contributors.
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If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to
Special thanks to:
Erin Magennis (Host): https://twitter.com/erinmagennis
Stanley:https://twitter.com/ScienceStanley
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Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

Dec 21, 2022 • 53min
Innovating in Longevity Biotech I Tyler Golato
Welcome to episode Nr. 7 of the DeSci Podcast! In this episode, Tyler Golato, Co-founder and CSO of Molecule DAO joins us as we discuss the problems of scientific research and funding and necessary changes that need to be made in the way funding is done.
We talk about the impact of decentralization in research, the requirements for allocating funds for research, and the future of Molecule and Bio-DAOs in general. Tyler also shares his background in biochemistry, molecular biology, and oncology research, and how his experiences led him to Molecule.
We hope you enjoy this episode and you can go through any of the topics discussed in the Podcast using the timestamps below.
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Timestamps:
0:40 Background story of Tyler Golato.
01:16 What drove your interest in healthcare?
12:45 What is the argument that research can be carried out in a decentralized manner and why does it matter?
18:17 What is the level of domain expertise needed to allocate funds for high-quality research? 21:20 What problems of scientific research and funding do you think requires decentralization to solve?
25:52 What is your vision for the future of Molecule and Bio-DAOs?
31:24 What other changes do you think need to be made in the way funding works?
34:52 What do you think about incentives in DeSci?
40:16 How would you approach the problem of waiting governance?
45:03 How do you determine success and measure outcomes?
47:20 What would you say is the bull case and bear case for DeSci?
51:05 How to get involved.
52:17 Outro
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If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to
Special thanks to:
Alex LaBossiere (Host): https://twitter.com/adlabossiere
(Check Alex his own podcast here: https://open.spotify.com/show/7lf0G6SBTArFlJYuHlPPoy?si=adcfa5f7a82d4708)
Patrick Malone: https://twitter.com/GolatoTyler
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Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao
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