

The DeSci Podcast
Molecule
Rethinking Science - Let's talk to the leaders of the decentralized science industry about the future of biotech. Brought to you by www.molecule.to
Want to join the stage? Apply as a speaker here: podcast@molecule.to
Want to join the stage? Apply as a speaker here: podcast@molecule.to
Episodes
Mentioned books

Jun 26, 2023 • 48min
Philanthropy's Role in Transforming Early-Stage Science Funding with Nadia Asparouhova
Welcome to another episode of the DeSci Podcast! We are excited to have Nadia Asparouhova, an independent researcher and author of "Working in Public: The Making and Maintenance of Open Source Software", as our guest today.
In this thought-provoking episode, we delve into the world of early-stage science funding and philanthropy. We discuss the role philanthropy plays in society and how it has evolved over the years. We also explore new funding mechanisms that have emerged to revolutionize the landscape of early-stage science, as well as the limitations and setbacks associated with these new funding mechanisms.
Additionally, we discuss the political challenges of early-stage science funding and the pivotal role that government and individual patrons should play in supporting early-stage science.
Please refer to the timestamps below to navigate through any of the topics discussed in the podcast.
____
⭐ Timestamps:
00:00 Intro
01:40 The role of philanthropy.
03:16 What drove your interest in science funding?
05:00 The uniqueness of tech
06:19 Understanding early stage science
08:27 New funding mechanisms for early stage science
13:02 Limitations to the new funding mechanisms
16:09 Importance of peer review
18:25 Common misconceptions about early stage science funding
21:47 Evolution of philanthropy
27:18 Philanthropy and the government
29:35 Political Challenges of early-stage science Funding
35:25 Legitimacy in early stage science funding
41:47 Science philanthropy: Then & Now
47:23 Outro
____
If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.
If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to
Special thanks to:
Lea Degen (host): https://twitter.com/lealeata
Nadia: https://twitter.com/nayafia
____
Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

Jun 15, 2023 • 34min
Revolutionizing Drug Discovery with AI - The Arctoris Approach with Martin-Immanuel Bittner
Welcome to another episode of the DeSci Podcast. Today, we had the privilege of having Dr. Martin-Immanuel Bittner as our guest. He is the CEO of Arctoris, which is the world's first fully automated platform for drug discovery, focused on accelerating the drug discovery process.
In this episode, we explore a variety of fascinating topics related to drug discovery. Dr. Bittner shares insights on the story behind building Arctoris and its mission to accelerate the drug discovery process. We also talk about how the drug development process has evolved over the years and the need to automate drug discovery research.
Other topics discussed were challenges stemming from the lack of rigorous funding in biotech, common misconceptions about automation, and many more.
Please feel free to navigate through any of the topics discussed in the podcast using the timestamps below.
____
⭐ Timestamps:
0:38 Intro
1:18 About Arctoris
2:52 What drove your interests in building Arctoris
4:23 Learnings from running Arctoris
5:53 What area needs more focus
8:03 Common misconceptions about automation
10:01 Flexibility in automation
13:44 Underexploited areas
16:09 Antibiotic resistance problem
17:58 Funding structures for Biotech companies
20:15 Investing in Biotech
22:38 The private sector and Academia
25:00 Changing beliefs on the need of automation in drug discovery
27:08 Contentious issues within your field
29:06 Implicit knowledge in drug discovery
____
If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.
If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to
Special thanks to:
Lea Degen (host): https://twitter.com/lealeata
Martin: https://www.linkedin.com/in/martinimmanuelbittner/?originalSubdomain=uk
____
Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

4 snips
Jun 4, 2023 • 36min
Martin Karlsson on AI x DeSci — Making research more efficient and accessible with Lateral
Martin Karlsson, CEO of Lateral, an innovative web app for scientists, discusses the best way to utilize Lateral's AI tools. We also explore the future of research, the cutting-edge capabilities of AI, and the importance of retaining human agency in the research process.

May 21, 2023 • 43min
LabDAO on Accelerating Advancements in Life Sciences through Accessible Scientific Tools
Niklas Rindtorff, co-founder of LabDAO, shares insights on conducting life science research online, benefits of collaboration within the scientific community, ownership rights in decentralized autonomous organizations, overlooked areas in decentralized science, differences in the private and public sector, and underappreciated aspects of academia.

May 9, 2023 • 38min
CryoDAO - Advancing Cryopreservation Research using Web3
Welcome to another episode of the DeSci Podcast. In this episode, we were joined by Dr. Emil Kendziorra and Kai Micah Mills, co-initiators of CryoDAO, a decentralized community dedicated to advancing cryopreservation research.
In this podcast, we discuss the field of cryonics, including its origins and how it has evolved over the years. Dr. Emil and Mills also explain how cryopreservation works, the underexploited areas in the field of Cryonics, and how it should be Improved.
We also address some of the common misconceptions about cryopreservation and recommended resources for those interested in learning more about Cryonics.
Finally, our guests share their thoughts on what the future of cryonics might hold and discuss some of the most contentious topics in the field.
Feel free to navigate through any of the topics discussed in the Podcast using the timestamps below.
____
⭐ Timestamps:
0:00 Intro
1:07 Brief overview of the field of Cryonics
3:45 Origin and Evolution of Cryonics
5:51 How does Cryopreservation work?
7:00 What drove your interest in Cryonics?
10:13 Underexploited areas in Cryonics.
11:36 What is the strongest argument against Cryonics?
13:35 How public perception of Cryonics has developed over the years.
16:29 Why pets instead of humans?
18:08 Why did you become a DAO?
22:43 Areas of overlap in cryonics.
25:32 The future of Cryonics.
28:37 What is the most contentious topic in Cryonics?
30:44 Common misconceptions about cryopreservation
33:27 Resources for people interested in the field of Cryonics.
35:39 How to get involved.
____
Special thanks to:
Lea Degen (host): https://twitter.com/lealeata
Kai Micah Mills: https://twitter.com/kaimicahmills
Dr. Emil Kendziorra: https://www.linkedin.com/in/emilkendziorra/
____
Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

Apr 12, 2023 • 56min
AthenaDAO: Reimagining and Empowering Women's Health
Welcome to another episode of the DeSci Podcast. In this one, we had the pleasure of talking with Laura Minquini, who is leading AthenaDAO, a community-led movement that is improving female reproductive health through the identification, financing, and support of research projects that are working on its potential cures. We talked about Laura's story, the global panorama of the problem that she is solving, and the journey and projections of the organization that she founded and bio.xyz helped shape.
Navigate through the topics discussed in this podcast using the timestamps below.
____
⭐ Timestamps:
0:55 Intro
1:50 About Laura Minquini
8:36 About AthenaDAO
11:21 Research in Female Reproductive Health Overview
15:49 AthenaDAO structure and projects in its pipeline
23:26 AthenaDAO's first IP-NFT
26:10 Aging & Fertility
33:41 Why scientists choose to join AthenaDAO
39:44 Bio.xyz acceleration journey
43:23 Strategies to raise awareness
47:35 How to Contribute to AthenaDAO
51:34 What would happen if AthenaDAO succeeds
54:18 Outro
____
If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.
If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to
Special thanks to:
Aastha (host): https://twitter.com/aasthajs
Laura Minquini: https://twitter.com/LauraMinquini
____
Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

Apr 3, 2023 • 52min
ValleyDAO on Building a Sustainable Future with Synthetic Biology
Welcome to another episode of the DeSci Podcast. In this episode, we were joined by ValleyDAO's Co-founder, Albert Anis, and Communications Lead, Morgan Richards.
In this video, Albert Anis and Morgan Richards provide a deep dive into the interesting field of Synthetic Biology, and the significant role that ValleyDAO plays in driving innovation in this area.
We also explored the traditional funding model for Synthetic Biology and the difficulties it presents for researchers. They then emphasize the need for a new, decentralized approach to funding and the importance of collaboration in the research field.
Albert and Morgan also go on to discuss the challenges of building in DeSci, and ValleyDAO's unique approach to incubating new projects, which involves providing funding, expertise, and a supportive community for researchers.
Feel free to navigate through any of the topics discussed in the Podcast using the timestamps below.
____
⭐ Timestamps:
0:40 Intro
1:18 Albert Anis’ Background
6:26 What drove your interest in Synthetic Biology?
11:19 About Valley DAO
15:33 What is Synthetic Biology?
19:58 The problem of the traditional model of funding Synthetic Biology.
24:42 What areas are ValleyDAO focused on?
31:26 ValleyDAO’s process of incubating other projects
36:23 Value of Web 3 tools to Synthetic Bio Researchers
41:20 Challenges of building in DeSci
45:50 Areas of Overlap in ValleyDAO
47:40 ValleyDAO upcoming projects
50:14 How to get involved
50:41 Outro
____
Special thanks to:
Alex LaBossiere (Host): https://twitter.com/adlabossiere
Albert Anis: https://twitter.com/thealbertanis
Morgan Richards: https://twitter.com/Mxltiplex
____
Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

Mar 22, 2023 • 32min
HairDAO: A Community-Led Movement to End Hair Loss For Good
Welcome to another episode of the DeSci Podcast. In this episode, we had the pleasure of talking with Andrew Verbinnen and Andrew Bakst from HairDAO, the second BioDAO ever to mint an IP-NFT. Their mission is to turn hair loss into a problem of the past by funding assets that they believe will accelerate its cure. Throughout the conversation, we delve into a variety of fascinating topics related to hair loss.
We explore the bigger picture of this issue and highlight the crucial role of DeSci in expediting the discovery of solutions. And our guests also provide valuable insights gained from their experience in building in this ecosystem, shining a light on the HairDAO community, as well as the exciting projects that they have funded and upcoming initiatives.
Navigate through the topics discussed in this podcast using the timestamps below.
____
⭐ Timestamps:
0:23 Intro
01:08 About Andrew Verbinnen
03:01 About Andrew Bakst
04:11 Why HairDAO
05:50 Hair Loss Research & Solutions State
10:17 Hair Loss Multiphase Problem
11:57 HairDAO Community
15:05 HairDAO’s First IP-NFT
16:53 Study of Prof. Ralf Paus
19:41 Crypto & Global Cooperation
20:37 First Patient Database in DeSci
22:43 Importance of IP-NFTs
25:02 Learnings from Building a BioDAO
27:01 HairDAO Vision
27:58 HairDAO Upcoming Initatives
31:11 Outro
____
If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to
Special thanks to:
Alex LaBossiere (Host): https://twitter.com/adlabossiere
Andrew Verbinnen: https://twitter.com/VerbinnenAndrew
Andrew Bakst: https://twitter.com/andrew_bakst
____
Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

Mar 15, 2023 • 53min
IP-NFT Technical Deep Dive: Token Standards, Decentralized Storage and UX
Welcome to this episode of the DeSci Podcast, where we dive deep into the technology behind IP-NFTs and explore the possibilities of decentralized data storage.
In this episode, Stefan Adolf, a senior web3 engineer at Molecule, and Benji Leibowitz, a former biotech venture capitalist and now a product manager at Molecule, discuss the modularity of IP-NFTs, the advantages of ERC721, 1155, and 3525 token standards.
We also discuss the benefits of Arweave and IPFS for metadata and storage, Lit Protocol and unlocking data, custodial wallets and MPC providers, the SDK for developers, and the possibilities of permissionless minting and open source strategies with v2 and v3 of the IP-NFT.
We hope you can learn a lot about the amazing possibilities of the decentralized tech stack and how you can build with IP-NFTs with this episode and feel free to use the timestamps below to navigate through the episode.
Navigate through the topics discussed in this podcast using the timestamps below.
____
Timestamps:
00:00 - 01:42 Intro
01:42 - 04:30 What is the IP-NFT and who should use it?
04:30 - 08:40 Token Advantages (ERC721, 1155, and 3525)
08:40 - 11:18 IP-NFT V2 (Mint-passes and Reservations)
11:18 - 12:40 Who is the ideal user for a min-pass?
12:40 - 17:24 Where is the metadata of an IP-NFT stored, and how is it structured?
17:24 - 25:19 Difference between web3 and web2 storage
25:19 - 29:21 Content gating with DAO tools
29:21 - 34:56 The role of Lit-Protocol within the IP-NFT
34:56 - 49:00 Frontend of the IP-NFTs and on web3 wallets
49:00 - 51:59 When can people start building on this technology (wen SDK?)
51:59 Outro
____
If you want to watch the Podcast on YouTube, you can find all the important links below. And if you want to join us on the show as a speaker or have guest ideas; please mail us at podcast@molecule.to
linktr.ee/thedescipodcast
Special thanks to:
Heinrich Tessendorf (Host): https://twitter.com/Heintess_GM
Stefan Adolf: https://twitter.com/stadolf
Benji Leibowitz: https://twitter.com/benjileibo
____
Let's connect:
Website: https://molecule.to/
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao

Feb 7, 2023 • 1h 43min
Vera Gorbunova on Longevity, Aging Biology and DeSci (Decentralized Science)
Welcome to another episode of the DeSci Podcast. In this episode, Vera Gorbunova, endowed Professor of Biology at the University of Rochester, co-director of the Rochester Aging Research Center, and co-founder of the new journal Aging Biology, run by scientists for scientists, shares with us a bit of her vast knowledge in the field of Longevity. She talked about the problems of the current scientific system, the partnership that her laboratory made with VitaDAO, and about the research that she is currently carrying out.
Navigate through the topics discussed in this podcast using the timestamps below.
____
Timestamps:
0:42 Intro
2:53 Vera's Life Story & Background
7:44 Comparative Longevity Approach
14:12 Serendipitous Discoveries
15:34 DNA Repairing Fidelity & Epigenetics Reprogramming
24:46 Who are the heroes of Vera
27:09 What Vera strongly believes and that other people disagree
32:28 Possible Nobel Prize-winning work
35:14 Chromatin: Hallmark of Aging
39:25 HSC Stem Cells
45:20 Extracellular Matrix
50:12 VitaDAO x Vera’s Lab Partnership on Naked Mole Rats
1:00:26 Programmed vs Damage Theory of Aging
1:11:07 Issues between Scientific Journal Publishers, Editors and Reviewers
1:17:42 Potential of Decentralized Scientific Journals & Peer-review
1:32:18 Final Conclusions
____
Special thanks to:
Sebastian Brunemeier (Host): https://twitter.com/sebastian_gero
Vera: https://www.linkedin.com/in/vera-gorbunova-64a97b46/
____
Let's connect:
Website: https://bit.ly/3d6nh2C
Twitter: https://twitter.com/Molecule_dao
Discord: https://discord.com/invite/moleculedao