The DeSci Podcast

Welcome to another episode of the DeSci Podcast! Today, we are delighted to host Stuart Buck. Stuart serves as a Senior Advisor at the Social Science Research Council and is the Executive Director of the Good Science Project—an organization dedicated to enhancing the funding and practice of science. In this episode, Stuart addresses key challenges in the scientific landscape, such as bureaucratic obstacles to funding and the distinction between basic and applied science. He emphasizes the interconnected nature of basic and applied research, highlighting how discoveries from basic research lay the foundation for applied innovations and challenges addressed through applied science inspire new questions in basic research. Moving further, Stuart shares his view on the metaphor of failure in science. According to him, failure is not synonymous with defeat; instead, encountering failures in scientific endeavors indicates that one is posing pertinent questions and pushing the boundaries of knowledge. Other topics covered in the podcast include scientific reproducibility, the measurement problem in science, enforcing data accessibility, and many more. Feel free to navigate through the various topics covered in the Podcast using the timestamps provided below. ___ ⭐ Timestamps: 0:00 Intro 01:27 Good science project main focus. 03:37 Stuart’s theory of social change 10:04 Areas that need improvement 13:00 Recommendation for young researchers 17:35 Why grantmakers tend to be conservative in funding basic science 21:45 Basic vs Applied research 24:15 The notion of failure in science 30:59 Revisiting anti-portfolio 37:37 The value of funding replication in research 43:45 The problem with metrics 46:49 Outro ____ If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below. If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at podcast@molecule.to Special thanks to Lea Degen: https://twitter.com/lealeata Stuart Buck: https://twitter.com/stuartbuck1 ____ Let's connect: Website: https://bit.ly/3d6nh2C X: https://twitter.com/Molecule_dao Discord: https://discord.com/invite/moleculedao

Brian Magierski, CEO and Founder of Cerebrum DAO, discusses the mission behind Cerebrum DAO, the motivations behind his interest in brain health research, and why he chose the DAO model. They also touch on topics like collaborating with biotech companies, maintaining scientific quality in decentralized funding, and how DAOs enable entrepreneurship.

Keith Comito, President at Lifespan, shares insights on aging research, attitudes towards lifespan extension, and the impact aging research can have on humanity. They discuss the relevance of studying history in tech, the limits to extending lifespan, and pros and cons of traditional science methods. The podcast explores contentious topics within the aging research field, the influence of religion on perspectives of aging, and the significance of aging research for societal benefits.

Michael Baran, Executive Director at WRDM and partner at Pfizer Ventures, delves into the revolutionary potential of decentralized science (DeSci). He explores how DeSci is redefining traditional biotech paradigms and enhancing investment models through decentralized autonomous organizations (DAOs). Michael discusses the risks in early-stage science investments, challenges in biopharma, and common misconceptions about the sector. He emphasizes the importance of maintaining scientific quality while navigating the complexities of innovation and funding in the evolving landscape.

Dr. Jocelynn Pearl, biotech scientist and co-founder of LabDAO, discusses the birth of Decentralized Biotech, the importance of incentivizing knowledge sharing, pros and cons of centralization in Biotech, limits of online collaboration, sharing tacit knowledge, funding for good projects, and contentious topics within LabDAO.

Juan Benet, Founder of Protocol Labs, discusses the translational science problem, cryptocurrency's impact on research, and the intersection of AI and future society.

Join Niklas Anzinger as he discusses investing in network states, startup cities, and over-regulated industries on this episode. Learn about Infinitia Funds, Prospera's mission, and the need for improved regulatory systems. Explore projects like Zuzalu focusing on extending human lifespans and enhancing health outcomes. Discover the potential for growth and innovation in fields like Longevity and Science through Network States and Startup Cities.

Welcome to another episode of the DeSci Podcast. Today, we were joined by Jesse Hudson, the Chief Legal Architect at Molecule, Chris Byrnes, an IP Legal Advisor also representing Molecule, and Benji Leibowitz, Product Manager at Molecule. The existing intellectual property (IP) system faces several challenges that hinder its effectiveness and innovation potential. Patent trolls, the system's lack of efficiency, and the high transaction costs associated with acquiring and enforcing IP rights further burden inventors, researchers, and scientific enterprises. In this episode, we explore the groundbreaking concept of IP Tokens and how they can help solve the issues plaguing the current IP system. We explain what IP Tokens are and how they differentiate from IP-NFTs. We also discuss how IP tokens could facilitate scientific entrepreneurship and how they open up decentralization in science by enabling a system where the community can partake in the governance processes. Navigate the various topics covered in the Podcast using the timestamps below. ____ ⭐ Timestamps: 0:00 Intro 2:11 About Jesse Hudson 2:54 About Chris Byrnes 5:47 Fundamental issues within the IP system 11:16 How Molecule facilitates Scientific entrepreneurship 20:12 Overview of Intellectual Property 32:09 What is an IP-NFT? 37:05 IP Tokens and why they matter. 51:11 Digitizing the process of IP licensing 1:02:41 IP Tokens and Decentralization 1:10:16 IP financing 1:16:31 Enforcing IP rights 1:22:22 Outro ____ If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below. If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to Special thanks to: Benji Leibowitz: https://twitter.com/benjileibo Jesse Hudson: https://twitter.com/jsshdsn Chris Byrnes: https://twitter.com/reimagineIP ____ Let's connect: Website: https://bit.ly/3d6nh2C Twitter: https://twitter.com/Molecule_dao Discord: https://discord.com/invite/moleculedao

Welcome to another episode of the DeSci Podcast! Today, we were joined by Ben Reinhardt, founder of Speculative Technologies, a nonprofit research organization that runs coordinated research programs to unlock groundbreaking innovations. In this episode, we explore the qualities that make funders exceptional and the key factors that contribute to successful startup grants. We also shed light on the social and financial asymmetries between grantor and grantee, highlighting their negative impact on the funding process. Other topics we discussed are the differences between small and large grants, limitations of grant-making programs, common misconceptions between the public and private sector and many more. Feel free to navigate through any of the topics discussed in the Podcast using the timestamps below. ____ ⭐ Timestamps: 0:00 Intro 1:46 Characteristics of good funders 6:39 Key factors for successful startup grants 13:02 Asymmetries in grantor-grantee relationships 16:20 Small and large grants 19:09 Coordination in research 26:50 Pros and cons of grants 30:28 Limitations and drawbacks of grant-making programs 36:10 Common misconceptions between the public and private sector 38:07 Contentious issues within your field 42:42 Reforming science funding 44:20 How do you approach research management? 46:52 Topics Ben wants to write about 52:04 Outro ____ If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to Special thanks to: Lea Degen (host): https://twitter.com/lealeata Ben Reinhardt: https://twitter.com/Ben_Reinhardt ____ Let's connect: Website: https://bit.ly/3d6nh2C Twitter: https://twitter.com/Molecule_dao Discord: https://discord.com/invite/moleculedao

Welcome to another episode of the DeSci Podcast! We are excited to have Nadia Asparouhova, an independent researcher and author of "Working in Public: The Making and Maintenance of Open Source Software", as our guest today. In this thought-provoking episode, we delve into the world of early-stage science funding and philanthropy. We discuss the role philanthropy plays in society and how it has evolved over the years. We also explore new funding mechanisms that have emerged to revolutionize the landscape of early-stage science, as well as the limitations and setbacks associated with these new funding mechanisms. Additionally, we discuss the political challenges of early-stage science funding and the pivotal role that government and individual patrons should play in supporting early-stage science. Please refer to the timestamps below to navigate through any of the topics discussed in the podcast. ____ ⭐ Timestamps: 00:00 Intro 01:40 The role of philanthropy. 03:16 What drove your interest in science funding? 05:00 The uniqueness of tech 06:19 Understanding early stage science 08:27 New funding mechanisms for early stage science 13:02 Limitations to the new funding mechanisms 16:09 Importance of peer review 18:25 Common misconceptions about early stage science funding 21:47 Evolution of philanthropy 27:18 Philanthropy and the government 29:35 Political Challenges of early-stage science Funding 35:25 Legitimacy in early stage science funding 41:47 Science philanthropy: Then & Now 47:23 Outro ____ If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below. If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to Special thanks to: Lea Degen (host): https://twitter.com/lealeata Nadia: https://twitter.com/nayafia ____ Let's connect: Website: https://bit.ly/3d6nh2C Twitter: https://twitter.com/Molecule_dao Discord: https://discord.com/invite/moleculedao