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The DeSci Podcast

Latest episodes

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4 snips
Jun 4, 2023 • 36min

Martin Karlsson on AI x DeSci — Making research more efficient and accessible with Lateral

Martin Karlsson, CEO of Lateral, an innovative web app for scientists, discusses the best way to utilize Lateral's AI tools. We also explore the future of research, the cutting-edge capabilities of AI, and the importance of retaining human agency in the research process.
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May 21, 2023 • 43min

LabDAO on Accelerating Advancements in Life Sciences through Accessible Scientific Tools

Niklas Rindtorff, co-founder of LabDAO, shares insights on conducting life science research online, benefits of collaboration within the scientific community, ownership rights in decentralized autonomous organizations, overlooked areas in decentralized science, differences in the private and public sector, and underappreciated aspects of academia.
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May 9, 2023 • 38min

CryoDAO - Advancing Cryopreservation Research using Web3

Welcome to another episode of the DeSci Podcast. In this episode, we were joined by Dr. Emil Kendziorra and Kai Micah Mills, co-initiators of CryoDAO, a decentralized community dedicated to advancing cryopreservation research. In this podcast, we discuss the field of cryonics, including its origins and how it has evolved over the years. Dr. Emil and Mills also explain how cryopreservation works, the underexploited areas in the field of Cryonics, and how it should be Improved. We also address some of the common misconceptions about cryopreservation and recommended resources for those interested in learning more about Cryonics. Finally, our guests share their thoughts on what the future of cryonics might hold and discuss some of the most contentious topics in the field. Feel free to navigate through any of the topics discussed in the Podcast using the timestamps below. ____ ⭐ Timestamps: 0:00 Intro 1:07 Brief overview of the field of Cryonics 3:45 Origin and Evolution of Cryonics 5:51 How does Cryopreservation work? 7:00 What drove your interest in Cryonics? 10:13 Underexploited areas in Cryonics. 11:36 What is the strongest argument against Cryonics? 13:35 How public perception of Cryonics has developed over the years. 16:29 Why pets instead of humans? 18:08 Why did you become a DAO? 22:43 Areas of overlap in cryonics. 25:32 The future of Cryonics. 28:37 What is the most contentious topic in Cryonics? 30:44 Common misconceptions about cryopreservation 33:27 Resources for people interested in the field of Cryonics. 35:39 How to get involved. ____ Special thanks to: Lea Degen (host): https://twitter.com/lealeata Kai Micah Mills: https://twitter.com/kaimicahmills Dr. Emil Kendziorra: https://www.linkedin.com/in/emilkendziorra/ ____ Let's connect: Website: https://bit.ly/3d6nh2C Twitter: https://twitter.com/Molecule_dao Discord: https://discord.com/invite/moleculedao
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Apr 12, 2023 • 56min

AthenaDAO: Reimagining and Empowering Women's Health

Welcome to another episode of the DeSci Podcast. In this one, we had the pleasure of talking with Laura Minquini, who is leading AthenaDAO, a community-led movement that is improving female reproductive health through the identification, financing, and support of research projects that are working on its potential cures. We talked about Laura's story, the global panorama of the problem that she is solving, and the journey and projections of the organization that she founded and bio.xyz helped shape. Navigate through the topics discussed in this podcast using the timestamps below. ____ ⭐ Timestamps: 0:55 Intro 1:50 About Laura Minquini 8:36 About AthenaDAO 11:21 Research in Female Reproductive Health Overview 15:49 AthenaDAO structure and projects in its pipeline 23:26 AthenaDAO's first IP-NFT 26:10 Aging & Fertility 33:41 Why scientists choose to join AthenaDAO 39:44 Bio.xyz acceleration journey 43:23 Strategies to raise awareness 47:35 How to Contribute to AthenaDAO 51:34 What would happen if AthenaDAO succeeds 54:18 Outro ____ If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below. If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to Special thanks to: Aastha (host): https://twitter.com/aasthajs Laura Minquini: https://twitter.com/LauraMinquini ____ Let's connect: Website: https://bit.ly/3d6nh2C Twitter: https://twitter.com/Molecule_dao Discord: https://discord.com/invite/moleculedao
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Apr 3, 2023 • 52min

ValleyDAO on Building a Sustainable Future with Synthetic Biology

Welcome to another episode of the DeSci Podcast. In this episode, we were joined by ValleyDAO's Co-founder, Albert Anis, and Communications Lead, Morgan Richards. In this video, Albert Anis and Morgan Richards provide a deep dive into the interesting field of Synthetic Biology, and the significant role that ValleyDAO plays in driving innovation in this area. We also explored the traditional funding model for Synthetic Biology and the difficulties it presents for researchers. They then emphasize the need for a new, decentralized approach to funding and the importance of collaboration in the research field. Albert and Morgan also go on to discuss the challenges of building in DeSci, and ValleyDAO's unique approach to incubating new projects, which involves providing funding, expertise, and a supportive community for researchers. Feel free to navigate through any of the topics discussed in the Podcast using the timestamps below. ____ ⭐ Timestamps: 0:40 Intro 1:18 Albert Anis’ Background 6:26 What drove your interest in Synthetic Biology? 11:19 About Valley DAO 15:33 What is Synthetic Biology? 19:58 The problem of the traditional model of funding Synthetic Biology. 24:42 What areas are ValleyDAO focused on? 31:26 ValleyDAO’s process of incubating other projects 36:23 Value of Web 3 tools to Synthetic Bio Researchers 41:20 Challenges of building in DeSci 45:50 Areas of Overlap in ValleyDAO 47:40 ValleyDAO upcoming projects 50:14 How to get involved 50:41 Outro ____ Special thanks to: Alex LaBossiere (Host): https://twitter.com/adlabossiere Albert Anis: https://twitter.com/thealbertanis Morgan Richards: https://twitter.com/Mxltiplex ____ Let's connect: Website: https://bit.ly/3d6nh2C Twitter: https://twitter.com/Molecule_dao Discord: https://discord.com/invite/moleculedao
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Mar 22, 2023 • 32min

HairDAO: A Community-Led Movement to End Hair Loss For Good

Welcome to another episode of the DeSci Podcast. In this episode, we had the pleasure of talking with Andrew Verbinnen and Andrew Bakst from HairDAO, the second BioDAO ever to mint an IP-NFT. Their mission is to turn hair loss into a problem of the past by funding assets that they believe will accelerate its cure. Throughout the conversation, we delve into a variety of fascinating topics related to hair loss. We explore the bigger picture of this issue and highlight the crucial role of DeSci in expediting the discovery of solutions. And our guests also provide valuable insights gained from their experience in building in this ecosystem, shining a light on the HairDAO community, as well as the exciting projects that they have funded and upcoming initiatives. Navigate through the topics discussed in this podcast using the timestamps below. ____ ⭐ Timestamps: 0:23 Intro 01:08 About Andrew Verbinnen 03:01 About Andrew Bakst 04:11 Why HairDAO 05:50 Hair Loss Research & Solutions State 10:17 Hair Loss Multiphase Problem 11:57 HairDAO Community 15:05 HairDAO’s First IP-NFT 16:53 Study of Prof. Ralf Paus 19:41 Crypto & Global Cooperation 20:37 First Patient Database in DeSci 22:43 Importance of IP-NFTs 25:02 Learnings from Building a BioDAO 27:01 HairDAO Vision 27:58 HairDAO Upcoming Initatives 31:11 Outro ____ If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to Special thanks to: Alex LaBossiere (Host): https://twitter.com/adlabossiere Andrew Verbinnen: https://twitter.com/VerbinnenAndrew Andrew Bakst: https://twitter.com/andrew_bakst ____ Let's connect: Website: https://bit.ly/3d6nh2C Twitter: https://twitter.com/Molecule_dao Discord: https://discord.com/invite/moleculedao
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Mar 15, 2023 • 53min

IP-NFT Technical Deep Dive: Token Standards, Decentralized Storage and UX

Welcome to this episode of the DeSci Podcast, where we dive deep into the technology behind IP-NFTs and explore the possibilities of decentralized data storage.  In this episode, Stefan Adolf, a senior web3 engineer at Molecule, and Benji Leibowitz, a former biotech venture capitalist and now a product manager at Molecule, discuss the modularity of IP-NFTs, the advantages of ERC721, 1155, and 3525 token standards. We also discuss the benefits of Arweave and IPFS for metadata and storage, Lit Protocol and unlocking data, custodial wallets and MPC providers, the SDK for developers, and the possibilities of permissionless minting and open source strategies with v2 and v3 of the IP-NFT. We hope you can learn a lot about the amazing possibilities of the decentralized tech stack and how you can build with IP-NFTs with this episode and feel free to use the timestamps below to navigate through the episode.  Navigate through the topics discussed in this podcast using the timestamps below. ____ Timestamps: 00:00 - 01:42 Intro 01:42 - 04:30 What is the IP-NFT and who should use it? 04:30 - 08:40 Token Advantages (ERC721, 1155, and 3525) 08:40 - 11:18 IP-NFT V2 (Mint-passes and Reservations) 11:18 - 12:40 Who is the ideal user for a min-pass? 12:40 - 17:24 Where is the metadata of an IP-NFT stored, and how is it structured? 17:24 - 25:19 Difference between web3 and web2 storage 25:19 - 29:21 Content gating with DAO tools 29:21 - 34:56 The role of Lit-Protocol within the IP-NFT 34:56 - 49:00 Frontend of the IP-NFTs and on web3 wallets 49:00 - 51:59 When can people start building on this technology (wen SDK?) 51:59 Outro ____ If you want to watch the Podcast on YouTube, you can find all the important links below. And if you want to join us on the show as a speaker or have guest ideas; please mail us at podcast@molecule.to linktr.ee/thedescipodcast Special thanks to:  Heinrich Tessendorf (Host): https://twitter.com/Heintess_GM Stefan Adolf: https://twitter.com/stadolf Benji Leibowitz: https://twitter.com/benjileibo ____ Let's connect: Website: https://molecule.to/ Twitter: https://twitter.com/Molecule_dao Discord: https://discord.com/invite/moleculedao
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Feb 7, 2023 • 1h 43min

Vera Gorbunova on Longevity, Aging Biology and DeSci (Decentralized Science)

Welcome to another episode of the DeSci Podcast. In this episode, Vera Gorbunova, endowed Professor of Biology at the University of Rochester, co-director of the Rochester Aging Research Center, and co-founder of the new journal Aging Biology, run by scientists for scientists, shares with us a bit of her vast knowledge in the field of Longevity. She talked about the problems of the current scientific system, the partnership that her laboratory made with VitaDAO, and about the research that she is currently carrying out.   Navigate through the topics discussed in this podcast using the timestamps below.  ____  Timestamps:  0:42 Intro 2:53 Vera's Life Story & Background 7:44 Comparative Longevity Approach 14:12 Serendipitous Discoveries 15:34 DNA Repairing Fidelity & Epigenetics Reprogramming 24:46 Who are the heroes of Vera 27:09 What Vera strongly believes and that other people disagree 32:28 Possible Nobel Prize-winning work 35:14 Chromatin: Hallmark of Aging 39:25 HSC Stem Cells   45:20 Extracellular Matrix 50:12 VitaDAO x Vera’s Lab Partnership on Naked Mole Rats 1:00:26 Programmed vs Damage Theory of Aging 1:11:07 Issues between Scientific Journal Publishers, Editors and Reviewers 1:17:42 Potential of Decentralized Scientific Journals & Peer-review 1:32:18 Final Conclusions   ____   Special thanks to:   Sebastian Brunemeier (Host): https://twitter.com/sebastian_gero   Vera: https://www.linkedin.com/in/vera-gorbunova-64a97b46/   ____   Let's connect:   Website: https://bit.ly/3d6nh2C Twitter: https://twitter.com/Molecule_dao Discord: https://discord.com/invite/moleculedao
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Jan 23, 2023 • 1h 14min

Michael P. Gibson on the 1517 Fund, Thiel Fellowship, and DeSci

Welcome to another episode of the DeSci Podcast. In this episode, Michael Gibson, co-founder and general partner of the 1517 fund, author of the new book ‘Paper Belt on Fire: How Renegade Investors Sparked a Revolt Against the University’ and one of the key people involved in launching the Thiel Fellowship in 2010 (where he helped Vitalik Buterin shape Ethereum), tells us about his vision of legacy institutions and how we can modernize them to encourage great global innovations once again.   You can already get his excellent book, discussed in the episode, on Amazon: https://www.amazon.com/Paper-Belt-Fire-Fight-Progress-ebook/dp/B099FZR4C3  Navigate through the topics discussed in this podcast using the timestamps below. ____   ⭐ Timestamps:  0:00 Intro 4:03 Book: ‘Paper Belt on Fire’ 9:26 Michael’s Background 14:20 Innovation in America is slowing down 19:20 Why Michael drop out the Academia 24:08 ‘If the college degree were a drug they would not be passed by the FDA’ 29:07 Cloud Universities 30:23 How to rebuild the Scientific Structure 38:59 VitaDAO and Alternative Funds 40:39 Accredited Investors 42:33 Investment Issues 44:26 Public Companies 46:00 New Disclosure Standard 49:03 Reproducibility Issues 53:42 Decentralized Science 1:07:00 How to motivate the next generation of great scientists   ____  If you want to join us on the show as a speaker or have guest ideas, please shoot us a mail at podcast@molecule.to  Special thanks to:   Sebastian Brunemeier (Host): https://twitter.com/sebastian_gero   Michael: https://twitter.com/William_Blake   ____   Let's connect:   Website: https://bit.ly/3d6nh2C Twitter: https://twitter.com/Molecule_dao Discord: https://discord.com/invite/moleculedao
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8 snips
Jan 15, 2023 • 48min

Vitalik Buterin on Decentralized Science, Aging, AI and Scientific Progress

Today we have a special one! In this episode, we have Vitalik Buterin as a guest, interviewed by Vincent Weisser.  They discuss the intersection of science and cryptocurrency, focusing on the concept of "decentralized science."  Vitalik explains how decentralized technologies, such as cryptocurrency, can improve science and the institutions of science by allowing for more diverse funding and collaboration among people. He also mentions specific tools, such as quadratic funding and decentralized autonomous organizations (DAOs), that can be used to fund and structure scientific projects.   He also highlights his current project, "Balvi", which is focused on addressing the COVID-19 situation and is funded by cryptocurrency. He also mentions the challenges of scaling up quickly and how this can be a good approach for established donors and talks about the use of technology such as DeSci and reputation systems to help solve the problem of determining who is trustworthy.    There is undoubtedly much more to be found in this episode and we hope you enjoy this conversation between Vitalik Buterin and Vincent Weisser. Make sure to skip between the timestamps below to find your favorite topics and learn more about the discussed topics through all the linked resources below. ____  Some of the resources discussed.  - Vitaliks blog: https://vitalik.ca/ - Vitaliks twitter: https://twitter.com/vitalikButerin - Decentralized Science Explainer https://ethereum.org/en/desci/ - Ending Aging book: https://en.wikipedia.org/wiki/Ending_Aging- Science DAOs like: http://vitadao.com/ - Some of the projects he supported https://cryptorelief.in/, https://impetusgrants.org/, https://www.sens.org/, https://arcinstitute.org/ - Balvi (Pandemic Prevention): https://twitter.com/VitalikButerin/status/1522017142320685057 - Quadratic Payments by Vitalik: https://vitalik.ca/general/2019/12/07/quadratic.html - DeSoc Paper by Puja, Glen and Vitalik: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4105763 - Progress: https://www.theatlantic.com/science/archive/2019/07/we-need-new-science-progress/594946/ - Network States: https://vitalik.ca/general/2022/07/13/networkstates.html - RadicalxChange: https://www.radicalxchange.org/ - The most important century https://www.cold-takes.com/most-important-century/ - Curveballs: pandemics, existential, risks from nuclear, ai, bio, wars - Recommend reading: https://80000hours.org/ - DeSoc x DeSci by Puja: https://www.youtube.com/watch?v=MUzwSPmP4nY ____   Timestamps:   00:00 - 00:37 Intro 00:37 - 06:36 Vitalik's definition of DeSci and what he is most excited about.   06:36 - 09:32 Improvements to retroactive or quadratic funding. 09:32 - 11:30 Vitalik on DeSoc in the context of science (Decentralized Society).   11:30 - 12:51 What to build at the intersection of DeSci and DeSoc?   12:51 - 13:46 Which areas of Science is Vitalik most excited about? 13:46 - 17:17 How the Shiba Inu tokens actually funded Covid research. 17:17 - 22:40 Why crypto is such an excellent funding method. 22:40 - 31:00 Which learnings did he incorporate into other projects like "Balvi"? 31:00 - 38:33 What's holding back scientific progress, and what is he most excited about?   38:33 - 44:37 The most important century ever? Vitalik on AI progress, Singularity, and existential risks.   44:37 - 46:47 What to build in the DeSci space? 46:47 - Vitalik's content recommendations in the science space. ___   Let's connect:   Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_dao Discord: https://discord.com/invite/moleculedao

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