
The Stephen Wolfram Podcast
Stephen Wolfram is the creator of Mathematica, Wolfram|Alpha and the Wolfram Language; the author of A New Kind of Science; and the founder and CEO of Wolfram Research. Over the course of nearly four decades, he has been a pioneer in the development and application of computational thinking—and has been responsible for many discoveries, inventions and innovations in science, technology and business.
On his podcast, Stephen discusses topics ranging from the history of science to the future of civilization and ethics of AI.
Latest episodes

May 28, 2025 • 1h 55min
What If We Had Bigger Brains? Imagining Minds beyond Ours
Discover the fascinating implications of larger brains on cognitive abilities and decision-making. Delve into how smell and sight shape our sensory experiences differently. Explore the evolution of human thought and the societal effects of brain size. Discuss the integration of new neuron types and the ethical questions around cognitive enhancement. Unpack the mysteries of neural networks and challenge traditional measures of intelligence. Finally, ponder how evolutionary factors influence our consciousness and cognitive capacities.

5 snips
May 28, 2025 • 1h 49min
Stephen Wolfram on Observer Theory
Dive into the intricate nature of observer theory, where perception shapes our understanding of the universe. Discover how observation intertwines with computation and the laws of physics, prompting fascinating questions about consciousness. Explore the striking differences between purpose-driven and mechanistic explanations in biology and physics. Unpack concepts like the Ruliad and its profound implications for science and philosophy. Finally, reflect on how these ideas enrich our human experience and connect us to the cosmos.

14 snips
May 21, 2025 • 1h 12min
Future of Science and Technology Q&A (May 16, 2025)
Dive into a thought-provoking exploration of AI's impact on copyright and creative ownership. Discover how AI may reshape personal computing systems and the ethical complexities of data privacy. The discussion also highlights the transformative role of AI in education, enhancing learning methods and assessments. Plus, enjoy nostalgic reflections on the evolution of personal computers, from the Apple II to modern machines, revealing their influence on our lives. Unpack the challenges and opportunities that lie ahead in our tech-driven future!

30 snips
May 20, 2025 • 1h 9min
Science & Technology Q&A for Kids (and others) [May 9, 2025]
Discover the fascinating world of consciousness and perception, where neuron activity shapes our experiences. Explore how brain structure influences our cognition and the philosophical implications of artificial intelligence. The podcast dives into the impact of neurological conditions on perception and discusses groundbreaking technologies in brain stimulation. It also tackles the intriguing challenges of brain transplants and the complexities of replicating unique neural connections. Join a journey through the brain's intricacies and the boundaries of reality!

May 20, 2025 • 1h 29min
Business, Innovation and Managing Life (May 14, 2025)
Stephen Wolfram answers questions from his viewers about business, innovation, and managing life as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-business-qaTopics discussed: Building companies that do real science - New frontiers in science, complex systems and generative art - Risks of algorithmic trading and LLMs in finance - Balancing science and profits - Blockchain ideas that aren't just buzzwords

15 snips
May 9, 2025 • 1h 21min
History of Science & Technology Q&A (May 7, 2025)
An insightful Q&A dives into the origins of historical inquiry, contrasting ancient and classical methodologies. It highlights the rising interest in archaeology since the 1700s and the challenges of preserving artifacts. The discussion touches on the evolving theories of space by iconic physicists and the subjective nature of historical narratives in science and politics. It emphasizes the significance of original documents for accurate historical understanding and uncovers the fascinating history of Planck's constant and its groundbreaking implications.

10 snips
May 9, 2025 • 1h 10min
Future of Science and Technology Q&A (May 2, 2025)
Stephen Wolfram tackles hot topics like the commercialization challenges of fusion energy and its comparison with fission. He dives into the evolution of AI and its potential to enhance human roles, particularly in healthcare. Philosophical insights into mathematics and its ties to the physical world spark thought-provoking discussions. The exploration of transfinite numbers highlights the intersection of math and science. Ethical implications of innovation are also examined, raising questions about technology's impact on human decision-making and creativity.

5 snips
May 9, 2025 • 1h 13min
Business, Innovation and Managing Life (April 30, 2025)
Explore the intriguing world of biotech entrepreneurship, where turning concepts into market-ready products is fraught with challenges. Dive into the evolving landscape of education, discussing whether college is still worth it and how practical skills are gaining value. Discover how AI is reshaping tutoring and university operations, as well as the need for secure home offices in today's remote work environment. Delve into the complexities of language learning across generations, highlighting the dynamic nature of vocabulary and communication.

May 9, 2025 • 1h 24min
History of Science & Technology Q&A (April 23, 2025)
Stephen Wolfram answers questions from his viewers about the history of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qaQuestions include: Do you know anything about the history of vaccines? When was the first vaccine developed and for what? - Isn't some important part of how vaccines were discovered completely lost to history? - When was the crucial importance of epigenetics discovered or realized? - What have been your interactions with early-day or notable biotech people & companies (Genentech etc.) and interplay between your own projects/techs and their development if any? - I had no idea Alan Turing was the progenitor of morphogenesis!

May 9, 2025 • 1h 22min
Science & Technology Q&A for Kids (and others) [April 18, 2025]
Stephen Wolfram answers general questions from his viewers about science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qaQuestions include: Books have been relatively unchanged—would you say that's a "technology" that has been mastered? - My son asks: Given there's a max amount of information you can store in a given region of space, how can we simulate complex systems (like brains or universes) without exceeding physical limits? - We're taught science discovers truth through observation and experiment. But in practice, I see science building mathematical models that work—sometimes treated as exact reality. How do you, as a scientist, separate calculation tools from physical truth in your actual work? Where does experience draw that line? - What lessons can we learn from the evolution of flight? Beyond the mechanics, Dawkins reflects In the book Flights of Fancy on the broader implications of flight evolution, considering what it reveals about natural selection, adaptation and the interconnectedness of life.