
The Stephen Wolfram Podcast
Stephen Wolfram is the creator of Mathematica, Wolfram|Alpha and the Wolfram Language; the author of A New Kind of Science; and the founder and CEO of Wolfram Research. Over the course of nearly four decades, he has been a pioneer in the development and application of computational thinking—and has been responsible for many discoveries, inventions and innovations in science, technology and business.
On his podcast, Stephen discusses topics ranging from the history of science to the future of civilization and ethics of AI.
Latest episodes

5 snips
May 9, 2025 • 1h 13min
Business, Innovation and Managing Life (April 30, 2025)
Explore the intriguing world of biotech entrepreneurship, where turning concepts into market-ready products is fraught with challenges. Dive into the evolving landscape of education, discussing whether college is still worth it and how practical skills are gaining value. Discover how AI is reshaping tutoring and university operations, as well as the need for secure home offices in today's remote work environment. Delve into the complexities of language learning across generations, highlighting the dynamic nature of vocabulary and communication.

May 9, 2025 • 1h 24min
History of Science & Technology Q&A (April 23, 2025)
Stephen Wolfram answers questions from his viewers about the history of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qaQuestions include: Do you know anything about the history of vaccines? When was the first vaccine developed and for what? - Isn't some important part of how vaccines were discovered completely lost to history? - When was the crucial importance of epigenetics discovered or realized? - What have been your interactions with early-day or notable biotech people & companies (Genentech etc.) and interplay between your own projects/techs and their development if any? - I had no idea Alan Turing was the progenitor of morphogenesis!

May 9, 2025 • 1h 22min
Science & Technology Q&A for Kids (and others) [April 18, 2025]
Stephen Wolfram answers general questions from his viewers about science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qaQuestions include: Books have been relatively unchanged—would you say that's a "technology" that has been mastered? - My son asks: Given there's a max amount of information you can store in a given region of space, how can we simulate complex systems (like brains or universes) without exceeding physical limits? - We're taught science discovers truth through observation and experiment. But in practice, I see science building mathematical models that work—sometimes treated as exact reality. How do you, as a scientist, separate calculation tools from physical truth in your actual work? Where does experience draw that line? - What lessons can we learn from the evolution of flight? Beyond the mechanics, Dawkins reflects In the book Flights of Fancy on the broader implications of flight evolution, considering what it reveals about natural selection, adaptation and the interconnectedness of life.

May 9, 2025 • 1h 13min
Future of Science and Technology Q&A (April 11, 2025)
Stephen Wolfram answers questions from his viewers about the future of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qaQuestions include: What is your view on photonic computing? - The Platonic solids have fascinated humans like us for years. Do you think the exploration of the four-dimensional hyper-Platonic solids may be useful? - Do you think there'll be, in the short-to-mid-term future, an AI architecture that manages to synthesize mental images to the level most humans do (mainly visual-spatial)? - Have you come across the synthetic biology field, e.g. biological computer chips, Neuralink? What is your opinion on such fields in science and the future? - Do you think training AI for generative video will end up with an internal model of physics?

Apr 29, 2025 • 1h 23min
Business, Innovation and Managing Life (April 9, 2025)
Stephen Wolfram answers questions from his viewers about business, innovation, and managing life as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-business-qaQuestions include: Did you see the recent news about the dire wolves coming back from extinction? Is there a genuine business for bringing back extinct animals? - There are also scientists making hybrids by injecting extinct animal DNA into modern animals. Recently they made woolly mice. - But would our atmosphere sustain dinosaur life, considering there was more oxygen back then? - At the remarkable age of 15, you began doing things that many would consider grown-up. I'm just curious as to how you went about attacking things that you simply felt like attacking. There are some people who wonder about stuff but don't necessarily know where to begin. How did you get so emboldened, if you can recall what that felt like? - I am curious about the "health trackers" you currently use (without revealing anything too personal!). I see at the time, you used a Fitbit Charge 2 and ServiceConnect, etc. Do you still use these, or have you switched to an Apple Watch etc.? Asking because I love your idea of tracking all kinds of health data, and I especially agree that automated is best. - Going back to your answer to my question about AI agents, which I agree that most websites will be used for LLMs instead of humans, should Wolfram|Alpha's next product be like Alexa—perhaps called "Wolfie"? - How to build that sort of confidence, then? What if I overthink at all times? How to challenge if I'm old already? - Should my next venture be based on an intellectual curiosity that might develop into something organically or a big ambition? - Do you think someone will come up with an internal fitness tracker which would be more accurate? - Is capital becoming more free to take risks or more constrained because of complexity of high-earning businesses? - How do you deal with real exogenous risks (i.e. global pandemic), with respect to innovation and commercialization thereof? - What are some early finance tips and tricks to teach kids to prepare them for the future? - I feel like I became a friend with ChatGPT—is it healthy? - ChatGPT and my daily-driver LLMs definitely know and remember more about me than I do myself at this point! - That seems a great idea. In the "Computational X" program, why not something to teach financial literacy and key financial math (compounding etc.), notably for kids, in interactive forms? - When designing humanoid robots, what do you think is a key component design of them?

17 snips
Apr 29, 2025 • 1h 20min
Science & Technology Q&A for Kids (and others) [April 4, 2025]
Explore the future of education as traditional textbooks face replacement by modern tools. Discover how AI can transform learning through curiosity-driven scientific inquiry. Delve into the complexities of friction, the universe, and the surprising role of technology in fostering creativity. Visual learning takes center stage, showcasing how 3D models can unlock complex concepts. Plus, unravel the challenges AI poses to encryption and the risks involved with social engineering in a tech-dominated world.

Apr 29, 2025 • 39min
History of Science & Technology Q&A (April 2, 2025)
In this engaging discussion, viewers learn about the intriguing intersection of science and entrepreneurship, exploring the journeys of historical figures like Kelvin and Ada Lovelace. The evolution of women in science and the rise of cloud labs revolutionizing research is also highlighted. Additionally, the podcast dives into the curious origins of walking meetings and reflects on the unexpected evolution of graphical user interfaces, showcasing how skeptics once viewed these innovations. It's a fascinating blend of history and modern insights!

Apr 29, 2025 • 1h 27min
Future of Science and Technology Q&A (March 28, 2025)
Stephen Wolfram answers questions from his viewers about the future of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qaQuestions include: What roles do category and type theory play in our understanding and the future of mathematics? - What would be an example of a hierarchy of types in theoretical physics? - Would you ever take a trip on Blue Origin or Space X ? Do you see more for the future of space travel happening sooner or later? - Do you think humans could/will evolve to adapt to space travel? - Say you could teleport to the Moon or Mars instead of travel by spaceship—would you take that travel option? - Space is a very hazardous place compared to Earth (radioactivity etc.). Chips in space would need to be very shielded and hence very expensive, I believe. - Why don't we use shielded nuclear waste to heat buildings (like in the basement attached to the HVAC system, in secure buildings)? - Closer to Earth, what do you see as the short-to-medium term future for inhabited orbital space stations and beyond that, in the longer-term future? - From genetic issues to space travel damage, do you think the main advances and solutions will come more from preventing or from repairing or an equal mix of both? - How would you think about AI-controlled humans if bionic brains become mainstream?

Mar 19, 2025 • 1h 24min
Future of Science and Technology Q&A (March 14, 2025)
Stephen Wolfram answers questions from his viewers about the future of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qaQuestions include: What, exactly, is an "AI agent"? "Agentic"? It seems like nobody knows what those words actually mean today. - Can you tell us about the future of media/information consumption? Will we become a society of "AI summaries" as our main form of information gathering? - Before AI summaries, there were encyclopedias and textbooks and CliffsNotes and such, and while they were useful and convenient, they never became de facto. - When will we get the first AI/robot news reporter? I see these being useful in cases of dangerous live broadcasting like hurricanes, to keep people up to date. - How far are we from LLMs generating a Stephen Wolfram–style long-form post, with similar elucidations, based on a short prompt of the key insight or topic? - When you say the teaching is delegated to the machine, are you saying that the machine is telling the student what to think about instead of just answering questions? - Can a sentient AI "understand" how humans learn? If we would delegate to them the teaching of human kids, would that be compatible with a biological point of view? - Have you ever considered entering the robotics space? A Wolfram Robotics, so to speak? - But if people delegate all calculations to the machines, then might it not happen that the machine actually learns to ask better questions than the humans can, since the machines have the experience built from the calculations and the humans don't? - What will AI not be able to do? Do you believe that something like that exists? - Tiny humans care about those questions about clouds and trees. - Robotic trade shows sound interesting. The company Boston Dynamics shows a lot of progress in the humanoid department. - Anything to say about the future of pi? (Happy Pi Day!) - Do you expect LLM development to hit significant diminishing returns within the next 2–3 years? - Automated theorem proving is so interesting. I'm trying to figure out how to make a theorem prover that demonstrably collapses a/the wavefunction. Like Stephen said; quantum LLMs.

Mar 18, 2025 • 1h 27min
Business, Innovation and Managing Life (March 12, 2025)
Stephen Wolfram answers questions from his viewers about business, innovation, and managing life as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-business-qaQuestions include: Is academia the only real career path if one just wants to learn and do research? - What are the risks for using AI/LLMs to do my technical writing job so I can focus on prompt engineering for the future of my field? - You've at the very least been told all sorts of interesting things that you can't currently repeat publicly. Would you ever consider writing a book or articles that would be locked for x years? - How would you guarantee an AI doesn't break an NDA accidentally? - Will "LLM psychologist" be a future career path? - Are websites receiving fewer visits due to the rise of AI agent/assistant apps that provide advice on products or services? - I, Robot by Asimov is a highly recommended, excellent collection of problems with the three laws. - Any suggestions on how to get someone to review my papers? I'm an antisocial autodidact with no academic backing. It's been impossible to get anyone to even consider my work. - If you make better rules, people will find better loopholes. - What are your thoughts on how a business specifically can do high-quality science? Companies like big AI labs seem to be doing well in this respect. Are they a good model for other companies doing science in other fields? - Historically, how much effort have great scientists with important contributions put into showing, or "marketing," their ideas? - The best teachers are the ones that ask the right questions from the students. Not telling them what to think. - How is a STEM background useful in entrepreneurship?