In Our Time: Science

In a programme first broadcast on April 12th 2018, Melvyn Bragg and guests discuss the contribution of George Stephenson (1781-1848) and his son Robert (1803-59) to the development of the railways in C19th. George became known as The Father of Railways and yet arguably Robert's contribution was even greater, with his engineering work going far beyond their collaboration. Robert is credited with the main role in the design of their locomotives. George had worked on stationary colliery steam engines and, with Robert, developed the moving steam engine Locomotion No1 for the Stockton and Darlington Railway in 1825. They produced the Rocket for the Rainhill Trials on the Liverpool and Manchester Railway in 1829. From there, the success of their designs and engineering led to the expansion of railways across Britain and around the world. with Dr Michael Bailey Railway historian and editor of the most recent biography of Robert StephensonJulia Elton Past President of the Newcomen Society for the History of Engineering and TechnologyandColin Divall Professor Emeritus of Railway Studies at the University of YorkProducer: Simon Tillotson. This programme is a repeat

Melvyn Bragg and guests discuss the pioneering scientist Rosalind Franklin (1920 - 1958). During her distinguished career, Franklin carried out ground-breaking research into coal and viruses but she is perhaps best remembered for her investigations in the field of DNA. In 1952 her research generated a famous image that became known as Photograph 51. When the Cambridge scientists Francis Crick and James Watson saw this image, it enabled them the following year to work out that DNA has a double-helix structure, one of the most important discoveries of modern science. Watson, Crick and Franklin's colleague Maurice Wilkins received a Nobel Prize in 1962 for this achievement but Franklin did not and today many people believe that Franklin has not received enough recognition for her work. With:Patricia Fara President of the British Society for the History of ScienceJim Naismith Interim lead of the Rosalind Franklin Institute, Director of the Research Complex at Harwell and Professor at the University of OxfordJudith Howard Professor of Chemistry at Durham UniversityProducer: Victoria Brignell.

Melvyn Bragg and guests discuss fungi. These organisms are not plants or animals but a kingdom of their own. Millions of species of fungi live on the Earth and they play a crucial role in ecosystems, enabling plants to obtain nutrients and causing material to decay. Without fungi, life as we know it simply would not exist. They are also a significant part of our daily life, making possible the production of bread, wine and certain antibiotics. Although fungi brought about the colonisation of the planet by plants about 450 million years ago, some species can kill humans and devastate trees. With:Lynne Boddy Professor of Fungal Ecology at Cardiff UniversitySarah Gurr Professor of Food Security in the Biosciences Department at the University of ExeterDavid Johnson N8 Chair in Microbial Ecology at the University of ManchesterProducer: Victoria Brignell.

The octopus, the squid, the nautilus and the cuttlefish are some of the most extraordinary creatures on this planet, intelligent and yet apparently unlike other life forms. They are cephalopods and are part of the mollusc family like snails and clams, and they have some characteristics in common with those. What sets them apart is the way members of their group can change colour, camouflage themselves, recognise people, solve problems, squirt ink, power themselves with jet propulsion and survive both on land, briefly, and in the deepest, coldest oceans. And, without bones or shells, they grow so rapidly they can outstrip their rivals when habitats change, making them the great survivors and adaptors of the animal world.WithLouise Allcock Lecturer in Zoology at the National University of Ireland, GalwayPaul Rodhouse Emeritus Fellow of the British Antarctic SurveyandJonathan Ablett Senior Curator of Molluscs at the Natural History MuseumProducer: Simon Tillotson.

In a programme first broadcast in 2017, Melvyn Bragg and guests discuss Gauss (1777-1855), widely viewed as one of the greatest mathematicians of all time. He was a child prodigy, correcting his father's accounts before he was 3, dumbfounding his teachers with the speed of his mental arithmetic, and gaining a wealthy patron who supported his education. He wrote on number theory when he was 21, with his Disquisitiones Arithmeticae, which has influenced developments since. Among his achievements, he was the first to work out how to make a 17-sided polygon, he predicted the orbit of the minor planet Ceres, rediscovering it, he found a way of sending signals along a wire, using electromagnetism, the first electromagnetic telegraph, and he advanced the understanding of parallel lines on curved surfaces. With Marcus du Sautoy Professor of Mathematics and Simonyi Professor for the Public Understanding of Science at the University of OxfordColva Roney-Dougal Reader in Pure Mathematics at the University of St AndrewsAnd Nick Evans Professor of Theoretical Physics at the University of SouthamptonProducer: Simon Tillotson.

Experts discuss the development of dinosaur feathers, the fascination with dinosaurs, the significance of Chinese feathered dinosaurs, determining the colors of ancient birds and dinosaurs, the preservation of melanin and keratin, mysteries in paleontology, and the coevolution of skin and feathers in dinosaurs.

Exploring bird migration and the factors that contribute to it. The podcast discusses the historical beliefs and scientific understanding of migration, tracking long-distance movement, and studying caged birds. It also explores the navigational challenges birds face, including the use of compass sense and olfactory cues. The podcast delves into the inheritance and factors influencing migration, the role of conspecifics and family members in migration cues, and the mechanisms and complexities of bird migration. Overall, it offers a fascinating insight into the incredible abilities and ongoing mysteries of bird migration.

Melvyn Bragg and guests discuss enzymes, the proteins that control the speed of chemical reactions in living organisms. Without enzymes, these reactions would take place too slowly to keep organisms alive: with their actions as catalysts, changes which might otherwise take millions of years can happen hundreds of times a second. Some enzymes break down large molecules into smaller ones, like the ones in human intestines, while others use small molecules to build up larger, complex ones, such as those that make DNA. Enzymes also help keep cell growth under control, by regulating the time for cells to live and their time to die, and provide a way for cells to communicate with each other. With Nigel Richards Professor of Biological Chemistry at Cardiff UniversitySarah Barry Lecturer in Chemical Biology at King's College LondonAnd Jim Naismith Director of the Research Complex at Harwell Bishop Wardlaw Professor of Chemical Biology at the University of St Andrews Professor of Structural Biology at the University of OxfordProducer: Simon Tillotson.

Melvyn Bragg and guests discuss the life and work of Louis Pasteur (1822-1895) and his extraordinary contribution to medicine and science. It is said few people have saved more lives than Pasteur. A chemist, he showed that otherwise identical molecules could exist as 'left' and 'right-handed' versions and that molecules produced by living things were always left-handed. He proposed a germ theory to replace the idea of spontaneous generation. He discovered that microorganisms cause fermentation and disease. He began the process named after him, pasteurisation, heating liquids to 50-60 C to kill microbes. He saved the beer and wine industries in France when they were struggling with microbial contamination. He saved the French silk industry when he found a way of protecting healthy silkworm eggs from disease. He developed vaccines against anthrax and rabies and helped establish immunology. Many of his ideas were developed further after his lifetime, but one of his legacies was a charitable body, the Pasteur Institute, to continue research into infectious disease.With Andrew Mendelsohn Reader in the School of History at Queen Mary, University of LondonAnne Hardy Honorary Professor at the Centre for History in Public Health at the London School of Hygiene and Tropical Medicineand Michael Worboys Emeritus Professor in the History of Science, Technology and Medicine at the University of Manchester Producer: Simon Tillotson.

Melvyn Bragg and guests discuss the life and ideas of Wolfgang Pauli (1900-1958), whose Exclusion Principle is one of the key ideas in quantum mechanics. A brilliant physicist, at 21 Pauli wrote a review of Einstein's theory of general relativity and that review is still a standard work of reference today. The Pauli Exclusion Principle proposes that no two electrons in an atom can be at the same time in the same state or configuration, and it helps explain a wide range of phenomena such as the electron shell structure of atoms. Pauli went on to postulate the existence of the neutrino, which was confirmed in his lifetime. Following further development of his exclusion principle, Pauli was awarded the Nobel Prize in Physics in 1945 for his 'decisive contribution through his discovery of a new law of Nature'. He also had a long correspondence with Jung, and a reputation for accidentally breaking experimental equipment which was dubbed The Pauli Effect.With Frank Close Fellow Emeritus at Exeter College, University of OxfordMichela Massimi Professor of Philosophy of Science at the University of EdinburghandGraham Farmelo Bye-Fellow of Churchill College, University of CambridgeProducer: Simon Tillotson.