Melvyn Bragg and guests discuss the shift that has gone on through the 20th century from our being an industrial society to what is often called ‘the information society’. Francis Fukuyama’s book, The Great Disruption talks of the third great shift in the whole history of humankind. Along with all the technological and economic changes, in the past thirty years we have seen massive social changes. What has been the cause of this shift and how will we recover the social cohesion that preceded it? With Francis Fukuyama, Hirst Professor of Public Policy, George Mason University, Washington DC and author of The Great Disruption: Human Nature and the Reconstitution of Social Order; Amos Oz, author and Professor of Hebrew Literature, Ben-Gurion University, Beer-Sheva.

Melvyn Bragg and guests discuss memory. At the start of the twentieth century Freud put memory at the centre of our psychology, and as the century has worn on what a nation remembers and what it should try to forget has become one of the binding political questions that modern societies face. As every second passes, humanity has a moment more to remember, and perhaps this fact alone goes a long way to explaining the ever changing role of memory, both in the mind of individuals and at the heart of the body politic. Memory, what to remember and when to forget, has personal and national implications. Whether we look to Chile, South Africa, Germany or Northern Ireland, these are all societies where the issue of memory is at the centre of the dilemmas and challenges they face. And in the mind of the individual too - as ever more forms of information crowd for space in our minds, and the image from someone else’s photograph can be more enduring than our own first hand experience of an event, can memory itself forever remain unchanged in its role within our psychology? Have our ways of remembering changed? Not in the sense neuro-biologists would explore the subject, but in its cultural and collective, as well as its individual, sense. “Memory is decidedly in fashion” writes Dr Nancy Wood, “whether attention is focused on the so-called return of repressed memories of the abused individual, or on the black holes in a nation’s recollection of its past. The topic of memory has become a compelling preoccupation”. With Professor Malcolm Bowie, Marshall Foch Professor of French Literature at Oxford University and Director of Oxford’s European Humanities Research Centre; Dr Nancy Wood, Chair of Media Studies, University of Sussex and author of Vectors of Memory.

Melvyn Bragg examines the history of what we know about the origins of the universe. Some four hundred years ago in Rome, one Giordano Bruno was burnt at the stake for his belief in other inhabited worlds - it’s a possibility which has fascinated scientists, writers, artists and the general public for centuries - and any consideration of the origins of life and matter on other planets, and indeed this one, inevitably raises huge questions. Do other worlds exist? How did our planet come into existence? How can we know anything at all about the origins of life and matter so many billions of years ago, and how has our thinking on these - amongst the deepest of questions - changed over the 20th century? Are we any closer to knowing whether other worlds exist and how our own planet came into being? And does the knowledge we have about these things change our perception of ourselves and our position in the universe?With Professor Sir Martin Rees, Astronomer Royal and Royal Society Research Professor in Astronomy and Physics, Cambridge University; Professor Paul Davies, theoretical physicist and Visiting Professor at Imperial College, London.

Melvyn Bragg and guests discuss the way perceptions of the importance of mathematics have fluctuated in the 20th century, the nature of mathematical ability, and what mathematics can show us about how life began, and how it might continue. Galileo wrote “this grand book the universe… is written in the language of mathematics”. It was said before Galileo and has been said since and in the last decades of the 20th century it is being said again, most emphatically. How important is maths in relation to other sciences at the end of the twentieth century - will it ever be made redundant, or is it increasingly crucial to our understanding of the world and ourselves? What insight can it give us into the origins of life, and the functioning of our brains, and what does it mean to say that maths has become more ‘visual’?With Ian Stewart, Professor of Mathematics and Gresham Professor of Geometry, University of Warwick; Brian Butterworth, Professor of Cognitive Neuroscience, University College, London.

Melvyn Bragg and guests discuss artificial intelligence. Can we create a machine that creates? Some argue so. And is consciousness, as we are, with headaches and tiffs and moods and small pleasures and sore feet - often all at the same time - capable of taking place in a machine? Artificial intelligence machines have been growing much more intelligent since Alan Turing’s pioneering days at Bletchley in World War Two. Its claims are now very grand indeed. It is 31 years since Stanley Kubrick and Arthur C Clarke gave us HAL - the archetypal thinking computer of the film 2001: A Space Odyssey. But are we any nearer to achieving the thinking, feeling computer? Or is it just a dream - and should it remain as one?With Igor Aleksander, Professor, Imperial College London and inventor of Magnus - a neural computer which he says is an artificially conscious machine; John Searle, Professor of Philosophy, University of California and one of only two people in the world to invent an argument, the Chinese Room Argument, which destroys the plausibility of the idea of conscious machines.

Melvyn Bragg examines the future of gene therapy and advances in evolutionary biology. Are we continuing to evolve? If so, what are the signs and if not, why not? And those apes, so very very near us in genetic kinship, why are they so far away in so much else, and will they ever evolve? And is evolution necessarily progression? If so, does our apparent lack of evolution mean lack of progress? Also on the evolutionary front, could electronic devices discover the means of self-replication, and what will that mean for us? The march of the life sciences after the discovery of DNA accelerates by the year but what are the implications?With Professor John Maynard Smith evolutionary biological theorist and Emeritus Professor of Biology at the University of Sussex; Colin Tudge, writer, journalist and Research Fellow at the Centre for Philosophy.

Melvyn Bragg and guests discuss the role of animals in humankind's search for knowledge. Since the Greek physician Galen used pigs for anatomical studies in the 2nd century, animals have been used by scientists to further human knowledge. Yet few, if any subjects in this country, raise such violent feelings and passions as animals and their place in our society. With the growing politicisation of animal rights, it is a subject which is increasing in intensity. Do animals have rights and do our needs permit us to use them still to enhance our own lives in the twentieth century? Is it still necessary to experiment on animals for the good of humankind? Or is that morally unacceptable and barbaric - particularly in the light of new research into animal consciousness?With Colin Blakemore, Professor of Physiology, Oxford University, President of the British Association for the Advancement of Science, Fellow of the Royal Society and targeted in the 1980s by animal welfare activists protesting at his research methods; Dr Lynda Birke, biologist, teacher at Lancaster and Warwick Universities, and previously worked for 7 years in animal behaviour at the Open University.

Melvyn Bragg and guests discuss the history of thought about space, and examines whether cyberspace has introduced a new concept of space in our world or if its roots are in Einsteinian physics. It would have seemed extraordinary to Dante or Newton, from their different perspectives, that at the end of the 20th century there would be learned scholars who would find no place for religion in the great schemes of thought and belief. In the 20th century our notions of physical space have been revolutionised. Einstein said that space was not a separate entity; we’ve probed and explored the outer reaches of our physical space with space flight, powerful telescopes and theoretical physics. But in the last 20 years, with the birth of the Internet, a virtual form of space has been introduced to us - cyberspace - where people can meet and communicate ideas; you sit at home, punch the keys and you can rove all over the world - the keyboard becomes a magic carpet. But does cyberspace introduce a new concept of space in our world? Or does it really have its roots in Einsteinian physics and even in Medieval theologyAccording to the science writer Margaret Wertheim, cyberspace - life on the surfing internet - gives us not only virtual reality, but a soul. Dr John Polkinghorne, the distinguished physicist and ordained priest in the C of E, is not happy with this news, but he does believe that religion is not destroyed by the new technology, and that latest theories in physics reinforce it. With The Reverend Dr John Polkinghorne, Fellow of Queen’s College, Cambridge and Canon Theologian of Liverpool; Margaret Wertheim, science writer and author of The Pearly Gates of Cyberspace: A History of Space from Dante to the Internet.

The podcast delves into the fascinating evolution of language, discussing how it sets humans apart from animals and exploring the infinite possibilities of sentences. It challenges traditional views on language formation, highlighting the intricate structures and patterns essential for learning languages. The exploration of unconscious processing in language comprehension and the importance of preserving linguistic diversity add further depth to the engaging discussion.

Dr. Juliet Mitchell and Adam Phillips discuss the continuing relevance of psychoanalysis in the 20th century. They explore Freud's impact on arts, history, and psychology, and question if psychoanalysis has failed to adapt to a science-dominated age. Topics include the challenges of evaluating psychoanalysis scientifically, Freud's theories on childhood development, and the significance of learning to speak in emotional comprehension and human behavior.