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The Drug Discovery World Podcast

Latest episodes

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Feb 2, 2024 • 9min

DDW Events SLAS2024: A welcome to SLAS 2024

For this year’s SLAS2024 conference in Boston (which takes place 3-7 February), DDW’s Megan Thomas narrates articles from the DDW SLAS2024 supplement as part of the DDW Events podcast series. This is episode one, called, “A welcome to SLAS 2024”, which includes two comment pieces. Thomas wrote the first one, “The journey from lab to patient”, which focuses on the theme of the track curated by DDW taking place in the Ignite Theater at SLAS 2024. The second is from SLAS Director of Marketing & Communications, Jill Hronek, called “Innovation at every turn: Hello SLAS2024”, in which Hronek shares her enthusiasm for the opportunities, products, technologies and stories that this event brings together. 
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Jan 29, 2024 • 14min

DDW Highlights: 29 January 2024

The podcast highlights the most studied disease area in 2023, advancements in the treatment of colorectal, pancreatic, lung cancer, and leukaemia. It also discusses challenges in clinical development, predictive analytics, digital patient profiles, positive phase one B study on treating metastatic colorectal cancer, enhanced response rates in cancer trials, investigational drug combinations for pancreatic cancer, microbiome-based immunotherapy in cancer treatment, and FDA orphan drug designation for AML treatment.
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Jan 29, 2024 • 15min

A safer option to opioid pain killers

Dr. Lynn Kirkpatrick, CEO of Ensysce Biosciences, discusses the development of a safer option to opioid pain killers that prevents abuse and overdose. Topics include Tripsin-Activated Abuse Protection, the MPAR approach to prevent prescription opioid overdose, and the advancement of a FDA approved product for chronic severe pain patients.
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Jan 22, 2024 • 14min

DDW Highlights: 22 January 2024

Exploring antibodies targeting spike protein epitopes to neutralize armicron variants, advancements in TB vaccine delivery, immune responses to SARS-CoV-2 variants, vaccine responses across age groups, and genetic modification in stem cell transplantation research.
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Jan 18, 2024 • 24min

Why is Europe a drug discovery epicentre?

This is the latest episode of the free DDW narrated podcast, titled: Why is Europe a drug discovery epicentre? It covers three articles written for Volume 23 – Issue 4, Fall 2022 of DDW. They are called: European drug discovery and development success stories, Basel: A centre for ground-breaking oncology, and On the European CGT landscape, zebras and the future of medicine. In the first article, Lu Rahman highlights some of the key players as, at the time of writing, we were starting to look beyond the pandemic, asking which areas of Europe’s drug discovery community we should be taking note of. In the second article, Dr Stephan Emmerth and Paul Eschmann, Basel Area Business & Innovation, explain the benefits of being based in Basel – the talent pool, global players, academic institutions and investors, for example. In the third article, Megan Thomas reflects on the cell and gene therapy landscape in Europe following Advanced Therapies Europe 2022.  You can also find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 
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Jan 15, 2024 • 15min

DDW Highlights: 15 January 2024

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates.  This week has seen a number of significant discoveries by researchers in academic institutions, in some cases in partnership with industry, emphasising the important role universities play in early-stage drug discovery. Perhaps most importantly, a new antibiotic was found that targets a Gram-negative pathogen, mRNA was used as an effective therapy for a rare liver disease, and a common immune cell was found to attack cancer. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 
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Jan 11, 2024 • 33min

Revolutionary technology for drug discovery and development

This podcast episode covers three written articles on the future of a cytomegalovirus vaccine, the role of predictive diagnostics in precision medicine, and making data work harder in the race to market. Topics include the challenges in developing CMV vaccines, the importance of diagnostics in personalized therapy, and leveraging data for faster drug development.
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Jan 11, 2024 • 31min

Investment trends for drug discovery and development

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business.    In this episode, Megan Thomas is in conversation with Owen Smith, Partner at 4BIO Capital. Owen began his investment career at life science venture capital, working with early-stage biotechnology companies. He holds an MSc in Experimental and Translational Therapeutics from the University of Oxford and is also qualified as an accountant. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 
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Jan 8, 2024 • 12min

DDW Highlights: 8 January 2024

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates.  The start of 2024 has seen quite a bit of regulatory activity, with the UK MHRA’s launch of a new procedure for assessing drugs, along with significant regulatory approvals for therapeutics for cytomegalovirus, melanoma, amyloidosis and multiple sclerosis. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 
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Jan 4, 2024 • 23min

Developing novel targeted radiopharmaceuticals for cancer treatment

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business.    In this episode, Megan Thomas is in conversation with Manfred Ruediger, CEO of Ariceum Therapeutics. Ariceum Therapeutics is focused on developing novel targeted radiopharmaceuticals for the treatment of cancer. 2023 was a pivotal year for the company from a strategic perspective, including a €22.75 million Series A extension in April 2023, a strategic research collaboration with UCB in May 2023, and the acquisition of Theragnostics in June 2023. It was also named Winner of Deal of the Year

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