ICU Primary PrepCast

Dive into the world of gastrointestinal pharmacology tailored for the ICU. Discover the vital role of stress ulcer prophylaxis and early enteral feeding in critically ill patients. Explore the contrast between pantoprazole and ranitidine, delving into their effects and interactions. Learn about the intricate mechanisms behind nausea and vomiting, along with various antiemetic classes. Lastly, uncover the pharmacology and clinical applications of prokinetic agents like erythromycin and metoclopramide, along with their therapeutic benefits and side effects.

Explore the fascinating world of respiratory pharmacology! Learn why oxygen is considered the most vital drug in the ICU and the risks of hyperoxia. Discover the differences between bronchodilators like Salbutamol and Salmeterol, and dive into the classifications of medications for acute severe asthma. Maddy shares insights on dosing, effects, and side effects of various drugs, providing valuable clinical implications. The conversation is wrapped up with a fun quiz that lightens the mood. Tune in for an engaging discussion on essential critical care pharmacology!

Dive into the world of anticonvulsant agents used in intensive care. Discover the pharmacological mechanisms behind key medications like sodium valproate and carbamazepine. Learn how phenytoin functions specifically in neurosurgical contexts and its effects on sodium channels. Explore the advantages of levetiracetam and its growing role in seizure management. This discussion is essential for practitioners looking to enhance their understanding of critical care pharmacology.

Explore the fascinating world of sedative agents used in the ICU. Discover the critical properties that make these medications effective and safe for critically ill patients. Dive deep into the pharmacology of propofol, including its potential toxicities. Learn about a comparative analysis of various sedatives like midazolam and dexmedetomidine, highlighting their unique advantages. Understand ketamine's dissociative effects and how its pharmacokinetics can impact treatment decisions. Uncover the contrasting cardiovascular effects of ketamine versus propofol at induction doses.

Dive into the fascinating world of opioids in the ICU. Explore how these powerful medications interact with opioid receptors and their physiological effects. Discover the importance of context-sensitive half-time, especially with drugs like fentanyl and remifentanil. Get a comprehensive look at morphine's pharmacology and its therapeutic uses. Plus, learn about naloxone's critical role in managing opioid overdoses, illustrated through a gripping case study. Get ready for an informative session packed with valuable insights!

Dive into the intricacies of neuromuscular blockade agents used in intensive care. Uncover the differences between depolarizing and non-depolarizing muscle relaxants, and how they interact with acetylcholine receptors to cause flaccid paralysis. Learn about the phases of neuromuscular blockade, and discover factors affecting the onset speed, such as dosage and patient factors. Explore mechanisms that boost the effectiveness of non-depolarizing agents, and examine the pharmacology of succinylcholine and other blockers, comparing their clinical applications.

Dive into the world of antihypertensive agents in critical care! Discover how various medications like glyceryl trinitrate and sodium nitroprusside work to manage blood pressure effectively. Learn about the role of calcium channel blockers and the unique distinctions between different classes. Unpack the pharmacology of metoprolol, including its vital clinical implications. Finally, compare the effects of clonidine and hydralazine, with a lighthearted twist on the topic of hypotension!

Explore the pharmacology and clinical scenarios of various diuretics like frasimide, hydrochlorothiazide, spironolactone, and acetazolamide. Learn about their mechanisms of action, adverse effects, and diverse applications in ICU settings.

Explore the pharmacology of anti-arrhythmic agents in the ICU setting with a focus on different types of action potentials in the heart and the classification and effects of various medications. Dive into the details of amiodarone and digoxin, including their mechanisms of action and side effects. Compare sotalol and flecainide in terms of pharmaceutical properties, classes, dosage, metabolism, and potential side effects.

Come and join us to learn about very commonly used class of drugs in intensive care i.e Inotropes. In this podcast, Maddy & Swapnil discuss about various inotropes in detail. We hope that this will be useful for all ICU trainees and nursing staff.