OPENPediatrics

In part 2 of this World Shared Practice Forum podcast, Dr. Paul Offit, Professor of Pediatrics in the Division of Infectious Disease and the Director of the Vaccine Education Center at The Children's Hospital of Philadelphia, updates listeners on the latest data in the field of COVID vaccination. He summarizes results from Pfizer’s phase 3 vaccine trial involving 5- to 11-year olds, and discusses the considerations behind the recommendation of a third "booster" vaccine dose for all eligible age groups. He also explains what is known about COVID virus variants, including Omicron. Learning Objectives: After listening to this podcast, learners will be able to: -Describe the basic structure and results of the Pfizer COVID vaccine trial involving five- to eleven-year-old children -Discuss the potential benefits of a third "booster" dose of COVID vaccine for different patient populations -Describe the risks of myocarditis and other inflammatory syndromes associated with COVID infection, and possibly with COVID vaccines -Compare the clinical characteristics of the emerging Omicron variant to earlier variants of the SARS-CoV-2 virus Articles referenced: • Offit PA. You Bet Your Life: From Blood Transfusions to Mass Vaccination, the Long and Risky History of Medical Innovation. 1st ed. Basic Books; 2021. (00:50) • Walter EB, Talaat KR, Sabharwal C, et al. Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age [published online ahead of print, 2021 Nov 9]. N Engl J Med. 2021;NEJMoa2116298. doi:10.1056/NEJMoa2116298 (2:52) • Daniels CJ, Rajpal S, Greenshields JT, et al. Prevalence of Clinical and Subclinical Myocarditis in Competitive Athletes With Recent SARS-CoV-2 Infection: Results From the Big Ten COVID-19 Cardiac Registry. JAMA Cardiol. 2021;6(9):1078-1087. doi:10.1001/jamacardio.2021.2065 (11:30) Intial publication: December 14, 2021 Citation: Offit PA, Daniel D, Burns JP. Pediatric Vaccine for COVID-19: Update on COVID-19 vaccine for 5-11 year olds, booster doses, and the Omicron variant. 12/2021. Online Podcast. OPENPediatrics. Offit PA, Daniel D, Burns JP. Pediatric Vaccine for COVID-19 Part 2: Update on the Vaccine for 5-11-yrs, Boosters, and Omicron. 12/2021. Online Podcast. OPENPediatrics. https://youtu.be/BcktvXuIsyI. Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu

In this podcast, Dr. Armstrong reviews how to identify and treat a leaking or dislodged gastrostomy tube (G-tube), which are two of the most common G-tube complications. Initial publication date: December 7, 2021 Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu

In this podcast, Dr. Lindsey Armstrong reviews the different types of gastrostomy tubes (G-tubes) and discusses the clinical situations in which each would be used. Initial publication date: December 2, 2021 Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu

In this World Shared Practice Forum podcast, Dr. Martin Kneyber, Chief of the Division of Paediatric Critical Care Medicine at the Beatrix Children’s Hospital, provides an insightful overview of the current state of thinking regarding the concepts of mechanical power and driving pressure in adult and pediatric mechanical ventilation. He provides his perspective on current evidence-based best practices for lung protective ventilation in pediatric ARDS, and highlights important areas for ongoing and future research. Learning Objectives: -Review the concepts and interrelations between mechanical power, driving pressure, plateau pressure -Understand the state of evidence linking driving pressure to outcomes in adult and pediatric patients receiving mechanical ventilation -Describe current evidence-based best clinical practices in adjusting mechanical ventilation in pediatric patients with acute respiratory distress syndrome (ARDS) Articles referenced: • Kneyber MC. Driving Pressure and Mechanical Power: The Return of Physiology in Pediatric Mechanical Ventilation. Pediatric Critical Care Medicine. 2021 Oct 1;22(10):927-9. (00:57) • Díaz, Franco, González-Dambrauskas, Sebastián, Cristiani, Federico, Casanova, Daniel R., Cruces, Pablo, Driving Pressure and Normalized Energy Transmission Calculations in Mechanically Ventilated Children Without Lung Disease and Pediatric Acute Respiratory Distress Syndrome, Pediatric Critical Care Medicine: 2021 Oct 1;22(10):870-8 (2:01) • Amato MB, Meade MO, Slutsky AS, et al. Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med. 2015;372(8):747-755. (5:58) • van Schelven P, Koopman AA, Burgerhof JGM, Markhorst DG, Blokpoel RGT, Kneyber MCJ. Driving Pressure Is Associated With Outcome in Pediatric Acute Respiratory Failure [published online ahead of print, 2021 Oct 20]. Pediatr Crit Care Med. 2021;10.1097/PCC.0000000000002848.(8:17) Publication Date: November 22, 2021. Citation: Kneyber M, Daniel D, Burns JP. Driving Pressure: The return of physiology in pediatric mechanical ventilation. 11/2021. Online Podcast. OPENPediatrics. https://soundcloud.com/openpediatrics/driving-pressure-the-return-of-physiology-in-pediatric-mechanical-ventilation-dr-martin-kneyber. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching a full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu

Dr. Kate Douglas, expert in working with interpreters in the clinical setting, shares best practices for effectively working with interpreters, including the importance of using professional medical interpreters, different methods of interpretation, and strategies for clear communication and understanding with interpreters during medical consultations.

In this World Shared Practice Forum podcast, Dr. Paul Offit, Director of the Vaccine Education Center, co-inventor of the rotavirus vaccine, member of the FDA Vaccine Advisory Committee, and attending physician in the Division of Infectious Diseases at Children’s Hospital of Philadelphia, shares his perspective on issues relating to COVID-19 vaccination in children. He provides historical perspective on prior pediatric vaccine development efforts, and shares his insights into the appraisal of scientific evidence and decision-making processes that are involved in federal approval of the COVID-19 vaccines.   After this podcast, listeners will be able to: -Understand the challenges behind COVID-19 vaccination development for children from a historical perspective -Describe the available evidence relating to antibody-dependent enhancement and vaccine-associated enhancement of disease with the COVID-19 vaccines -Describe the considerations involved in federally approving COVID-19 vaccines for children Initial publication date: October 22, 2021 Citation: Offit P, Daniel D, Burns JP. Pediatric Vaccine for COVID-19 Part 1. 10/2021. Online Podcast. OPENPediatrics. https://soundcloud.com/openpediatrics/pediatric-vaccine-for-covid-19-part-1-by-dr-paul-offit-for-openpediatrics. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu

In this Nursing World Shared Practice Forum podcast, Dr. Patricia Dwyer and Ms. Michelle Schuster share their research on Post-Traumatic Stress Disorder (PTSD) in the nursing field. They discuss how to identify symptoms and potential causes of PTSD for nurses. Dr. Patricia Dwyer and Ms. Michelle Schuster also discuss which nursing subspecialties carry a higher risk for PTSD and offer coping strategies for managing symptoms. Learning Objectives • Identify symptoms of PTSD • Recognize which personality types could be more susceptible to PTSD • Learn the prevalence rate of PTSD amongst pediatric subspecialties • List coping strategies for managing PTSD symptoms Publication Date: October 19, 2021. Citation: Dwyer P, Schuster M, DeGrazia M. Mental Health and PTSD in the Nursing Profession. 10/2021. Online Podcast. OPENPediatrics. https://soundcloud.com/openpediatrics/mental-health-and-ptsd-in-the-nursing-profession Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching a full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu

This podcast will provide information about the diagnosis and management of child abuse, with a focus on the skeletal and cutaneous manifestations of physical abuse. Initial Publication Date: September 29, 2021 Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu

In Part Two of this special World Shared Practice Forum podcast, Dr. Robert Tasker, Editor-in-Chief of the journal Pediatric Critical Care Medicine, discusses the journal’s top publication priorities and how those priorities direct what works get published. Dr. Tasker gives his insights on publications that can be followed by clinicians looking to stay up to date on emerging trends and research related to the field of pediatric critical care medicine. After this podcast, listeners will be able to: -Predict a range of topics that we may see in upcoming journal publications -Understand the prioritization that journals apply when choosing the content that is published -Recognize which publications should be followed by clinicians looking to stay up to date Articles referenced: • Horvat C. Statistical Note: Confounding and Causality in Observational Studies. Pediatr Crit Care Med. 2021;22(5):496-498. doi:10.1097/PCC.0000000000002702 (06:55) • Beshish AG, Jahadi O, Mello A, Yarlagadda VV, Shin AY, Kwiatkowski DM. Hyperoxia During Cardiopulmonary Bypass Is Associated With Mortality in Infants Undergoing Cardiac Surgery. Pediatr Crit Care Med. 2021;22(5):445-453. doi:10.1097/PCC.0000000000002661 (07:18) • Peters MJ. Linking Hyperoxia and Harm: Consequence or Merely Subsequence?. Pediatr Crit Care Med. 2021;22(5):501-503. doi:10.1097/PCC.0000000000002709 (07:28) • Bartman T, Brilli RJ. Quality Improvement Studies in Pediatric Critical Care Medicine. Pediatr Crit Care Med. 2021;22(7):662-668. doi:10.1097/PCC.0000000000002744 (07:57) • Rotta AT. Randomized Controlled Trial of Negative Pressure Ventilation: We First Need a National Patient Registry. Pediatr Crit Care Med. 2021;22(6):e369-e370. doi:10.1097/PCC.0000000000002743 (10:05) • Kneyber MCJ. Randomized Controlled Trial of Negative Pressure Ventilation: We First Need Characterized Physiology. Pediatr Crit Care Med. 2021;22(6):e371-e372. doi:10.1097/PCC.0000000000002742 (10:08) • Schober ME, Pavia AT, Bohnsack JF. Neurologic Manifestations of COVID-19 in Children: Emerging Pathophysiologic Insights. Pediatr Crit Care Med. 2021;22(7):655-661. doi:10.1097/PCC.0000000000002774 (10:55) Publication date: September 24, 2021 CV Citation: Tasker R, Daniel D, Wolbrink TA. Emerging Trends in Research: Journal Prioritization. 9/2021. Online Podcast. https://youtu.be/DQ4RNFxgK6Q Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching a full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu

In this podcast, Dr. Barry Kussman discusses the basic principles and application of cerebral oximetry in pediatric anesthesia. Initial publication date: September 13, 2021. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching a full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu