Neurology® Podcast

1) Neurology® Clinical Practice: Clinical Exome Sequencing in Neurologic Disease 2) What's Trending: Interview with Natalia del Campo about her paper on relationship of regional brain beta-amyloid to gait speed3) Topic of the month: Neurology Today story about pioglitazone found to be associated with a lower risk of secondary stroke in Non-diabetic patients with insulin resistanceThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Brent Fogel about his Neurology: Clinical Practice paper on clinical exome sequencing in neurologic disease. Dr. Ted Burns is interviewing Dr. Natalia del Campo for our "What's Trending" feature of the week about her paper on relationship of regional brain beta-amyloid to gait speed. Dr. Andy Southerland interviews Dr. Walter Kernan about a Neurology Today story on the topic of pioglitazone found to be associated with a lower risk of secondary stroke in Non-diabetic patients with insulin resistance.DISCLOSURES: Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Fogel received speaker honoraria from the American Academy of Neurology and American Physician Institute for Advanced Professional Studies; received funding for travel from American Physician Institute for Advanced Professional Studies and National Ataxia Foundation; receives research support from American Physician Institute for Advance Professional Studies, National Ataxia Foundation and the NIH.Dr. Southerland serves as Podcast Deputy Editor for Neurology; receives research support from the American Heart Association-American Stroke Association National Clinical Research Program, American Academy of Neurology, American Board of Psychiatry and Neurology, Health Resources Services Administration and the NIH; has a provisional patent application titled: "Method, system and computer readable medium for improving treatment times for rapid evaluation of acute stroke via mobile telemedicine;" and gave legal expert review.Dr. Kernan academic institution receives research support from Takeda Pharmaceutical Company Limited and the NIH.NO CME WILL BE OFFERED THIS WEEK.

1) Neurology® Neuroimmunology & Neuroinflammation: VZV in biopsy-positive and -negative giant cell arteritis: analysis of 100+ temporal arteries2) What's Trending: Interview with Kimberley R. Barker about "altmetrics"3) Topic of the month: Neurology Today story about epidemiologists tracking possible links between Zika virus, microcephaly, and Guillain–Barre syndromeThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Don Gilden about his Neurology: Neuroimmunology & Neuroinflammation paper on varicella zoster virus in over 100 temporal arteries that showed clinical features of giant cell arteritis. Dr. Andy Southerland is interviewing Kimberley R. Barker for our "What's Trending" feature of the week about "altmetrics." Dr. Ted Burns interviews Dr. James Sejvar about a Neurology Today story on the topic of epidemiologists tracking possible links between Zika virus, microcephaly, and Guillain–Barre syndrome.DISCLOSURES: Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Gilden serves as Senior Associate Editor for Journal of NeuroVirology, serves as an editorial Board member of In Vivo, Journal of Virology, Scientific American Medicine, Virus Genes, Neurology®, and the Journal of the Nuerological Sciences; receives research support from the NIH.Dr. Southerland serves as Podcast Deputy Editor for Neurology; receives research support from the American Heart Association-American Stroke Association National Clinical Research Program, American Academy of Neurology, American Board of Psychiatry and Neurology, Health Resources Services Administration and the NIH; has a provisional patent application titled: "Method, system and computer readable medium ofr improving treatment times for rapid evaluation of acute stroke via mobile telemedicine;" and gave legal expert review.NO CME WILL BE OFFERED THIS WEEK.

1) The association between hospitalization and care after transient ischemic attack or minor stroke2) e-Pearl topic: Neuroretinitis3) Topic of the month: Migraine awareness seriesThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Andy Southerland interviews Dr. Moira Kapral about her paper on the association between hospitalization and care after transient ischemic attack or minor stroke. Dr. Sarah Wesley is reading our e-Pearl of the week about neuroretinitis. Dr. Tesha Monteith interviews Dr. Stephen Silberstein about the topic of migraine clinical trials: A drug therapy and neuromodulation update. DISCLOSURES: Dr. Southerland serves as Podcast Deputy Editor for Neurology; receives research support from the American Heart Association-American Stroke Association National Clinical Research Program, American Academy of Neurology, American Board of Psychiatry and Neurology, Health Resources Services Administration and the NIH; has a provisional patent application titled: "Method, system and computer readable medium for improving treatment times for rapid evaluation of acute stroke viamobile telemedicine;" and gave legal expert review.Dr. Kapral serves as Guest Editor for Cardiovascular Quality and Outcomes; serves as an editorial board member of Circulation; receives research support from the Heart and Stroke Foundation of Canada.Dr. Wesley serves on the editorial team for the Neurology® Resident and Fellow Section.Dr. Monteith serves as an editorial advisory board member for Neurology Now and receives research support from the NIH.Dr. Silberstein serves as an editorial board member of Cephalalgia, Current Pain and Headache Reports, CNS Drugs, Topics in Pain Management and Neurology®; serves on the scientific advisory board for Alder, Allergan, Inc., Amgen, Avanir, eNeura, ElectroCore Medical, Medscape, Medtronic, Inc., Mitsubishi Tanabe Pharma Corporation, Neuralieve, NINDS, Pfizer Inc, Supernus and Teva Pharmaceutical Industries Ltd.; is a consultant for Allergan, Inc., Amgen, eNeura, ElectroCore Medical, Mitsubishi Tanabe, Medtronic, Inc., Neuralieve, Pfizer, Inc, Supernus and Teva Pharmaceutical Industries Ltd.; receives research support from American Headache Society®, International Headache Society and the NIH.

1) Standardized EEG interpretation accurately predicts prognosis after cardiac arrest2) e-Pearl topic: Panayiotopoulos syndrome3) Topic of the month: Migraine awareness seriesThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jennifer Fugate interviews Dr. Tobias Cronberg about his paper on standardized EEG interpretation and how it predicts prognosis after cardiac arrest. Dr. Sarah Wesley is reading our e-Pearl of the week about Panayiotopoulos syndrome. Dr. Tesha Monteith interviews Dr. Messoud Ashina about the topic of neuroimaging biomarkers and human models for new drug targets: Lessons from PACAP38. DISCLOSURES: Dr. Cronberg receives research support from the Regional Research Support, Region Skane, The Swedish Heart and Lung Association, The Skane University Hospital Foundations, The Gyllenstierna-Krapperup Foundation, The Swedish Society of Medicine, The Koch Foundation and The Segerfalk Foundation.Dr. Wesley serves on the editorial team for the Neurology® Resident and Fellow Section.Dr. Monteith serves as an editorial advisory board member for Neurology Now and receives research support from the NIH.Dr. Ashina serves as an associate editor of Cephalgia Member of advisory board: The Journal of Headache and Pain; is a consultant or scientific adviser for the ATI, Allergan, Inc., Amgen and Alder Biopharmaceuticals, Inc.; received an honoraria for lecturing from Allergan, Inc.; receivesresearch support from the Research Foundation of the Capital Region of Denmark, the Danish Council for Independent Research-Medical Sciences, the Novo Nordisk Foundation, IMK Almene Foundation, and the Cool Sorption Foundation.

1) Dichlorphenamide in periodic paralysis 2) What's Trending: Editorial on the Zika Virus and what the neurologist wants to know3) Topic of the month: Migraine awareness seriesThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Valeria Sansone about her paper on dichlorphenamide in periodic paralysis. Dr. Ted Burns is interviewing Dr. Gretchen Birbeck for our "What's Trending" feature of the week about her editorial on the Zika Virus and what the neurologist wants to know. Dr. Tesha Monteith interviews Dr. Peter Goadsby about the topic of science behind lifestyle factors: Our basic instincts and the migraine brain. DISCLOSURES: Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Birbeck serves as Section Editor and Curator for Without Borders mini-site Neurology®; receives research support from the NIH and Dana Foundation Neuroimaging Grant.Dr. Monteith serves as an editorial advisory board member for Neurology Now and receives research support from the NIH.Dr. Goadsby serves as an editorial board member for Journal Watch Neurology; receives royalties from the publication of Mechanism and Management of Headache. (7th ed.); was a consultant for Alder Bio, Allergan, Inc., Amgen, ATI, Boehringer Ingelheim, BMS, Boston Scientific, Colucid, Coherex, DrReddy, Eli Lilly and Company, Gammacore, GlaxoSmithKline, Impax, J&J Linde Gases, Lundbeck Inc., MAP Pharmaceuticals, Medtronic, Inc., MSD, Neuralieve, Nevrocorp, Pfizer Inc, Zogenix; receives research support from Amgen and Allergan, Inc.; has worked with legal firms handling patent matters.

1) Mid-life exercise blood pressure, heart rate and fitness relate to brain volume two decades later2) What's Trending: Antibiotic-associated encephalopathy 3) Topic of the month: Migraine awareness seriesThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Burns interviews Dr. Nicole Spartano about her paper on the mid-life exercise blood pressure, heart rate and fitness and how it relates to brain volume two decades later. Dr. Ted Burns is interviewing Dr. Shamik Bhattacharyya for our "What's Trending" feature of the week about his paper on antibiotic-associated encephalopathy. Dr. Tesha Monteith interviews Dr. Aarno Palotie about the topic of migraine genetics: What have we learned. DISCLOSURES: Dr. Jeff Burns serves on the editorial board for Journal of Alzheimer's Disease; receives royalties for the publications of Early diagnosis and treatment of mild cognitive impairment and Dementia: An atlas of investigation and diagnosis; is a consultant for PRA International and receives research support from the NIH, Alzheimer's Drug Discovery Foundation, Elan, Janssen Pharmaceuticals Inc., Wyeth, Pfizer Inc, Novartis Pharmaceuticals Ltd, Danone, Avid Radiopharmaceuticals, Merck Serono and for clinical trials.Dr. Spartano receives research support from the NIH.Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Monteith serves as an editorial advisory board member for Neurology Now and receives research support from the NIH.Dr. Palotie serves as a member of the Pfizer Genetics Scientific Advisory Panel; receives research support from Finnish Academy, European Union NIH, NINDS, Juselius Foundation and Finnish Foundation for Cardiovascular Research.

1) Neurology® Clinical Practice article titled: How do you treat anti-NMDA receptor encephalitis?2) e-Pearl topic: Primary lateral sclerosis3) Topic of the month: Pediatric multiple sclerosis This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Lara Marcuse interviews Dr. Luca Bartolini about his Neurology: Clinical Practice paper on how you treat anti-NMDA receptor encephalitis. Dr. Steve O'Donnell is reading our e-Pearl of the week about primary lateral sclerosis. In the next part of the podcast Dr. Nick Brenton interviews Dr. Leigh Charvet about the topic of cognitive, emotional and behavioral outcomes in pediatric multiple sclerosis. DISCLOSURES: Dr. Bartolini serves as Section Editor for Neurology Clinical Practice.Dr. O'Donnell serves on the editorial team for the Neurology Resident and Fellow Section.Dr. Charvet has received research support from Novartis.NO CME WILL BE OFFERED THIS WEEK.

1) Statin pretreatment is associated with better outcomes in large-artery atherosclerotic stroke2) e-Pearl topic: Fatal familial insomnia3) Topic of the month: Pediatric multiple sclerosis This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Andy Southerland interviews Dr. Georgios Tsivgoulis about his paper on how statin pretreatment is associated with better outcome in large-artery atherosclerotic stroke. Dr. Steve O'Donnell is reading our e-Pearl of the week about fatal familial insomnia. In the next part of the podcast Dr. Ruth Ann Marrie interviews Dr. Emmanuelle Waubant about the topic of vitamin D in pediatric multiple sclerosis. DISCLOSURES: Dr. Southerland serves as Podcast Deputy Editor for Neurology; serves as Clinical Research Advisor for Totier Technologies, Inc.Dr. Tsivgoulis serves as Associate Editor for Neurosonology; serves as an editorial board member of Journal of Neuroimaging; and receives research support from the European Regional Development Fund.Dr. O'Donnell serves on the editorial team for the Neurology Resident and Fellow Section.Dr. Marrie serves as an editorial board member of Neurology and Multiple Sclerosis Journal; receives research support for clinical trials from Sanofi-Aventis, from the Canadian Institutes of Health Research, Research Manitoba, from Multiple Sclerosis Society of Canada and the National Multiple Sclerosis Society, from Multiple Sclerosis Scientific Foundation and from Consortium of Multiple Sclerosis Centers; received research support from the Public Health Agency of Canada.Dr. Waubant serves on the scientific advisory board for Novartis; serves as an editorial board member of Annals of Clinical and Translational Neurology; is an ad hoc consultant for Roche and MedDay; received funding for travel for one educational physician lecture from Genentech, Inc.; receives royalties from the publication of the book Demyelinating disorders of the central nervous system in childhood; receives research support for trials of ocrelizumab in PPMS (Roche), and fingolimod in pediatric MS (Novartis); receives research support from the National Multiple Sclerosis Society, the Race to Erase MS and NIH.

1) Metabotropic glutamate receptor type 1 autoimmunity: Clinical features and treatment outcomes2) What's Trending: Editorial on if stress could cause a stroke3) Topic of the month: Pediatric multiple sclerosis This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Kathryn Nevel interviews Dr. Andrew McKeon about his paper on clinical features and treatment outcomes of metabotropic glutamate receptor type 1 autoimmunity. Dr. Ted Burns is interviewing Dr. Jennifer Majersik for our "What's Trending" feature of the week about her editorial on if stress could cause a stroke. In the next part of the podcast Dr. Ruth Ann Marrie interviews Dr. Ann Yeh about the topic of exercise in pediatric multiple sclerosis. DISCLOSURES: Dr. McKeon receives research support from Medimmune, Inc.Dr. Ted Burns serves as Podcast Editor for Neurology; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Majersik serves as an editorial board member of Neurology; and receives research support from the NIH.Dr. Marrie serves as an editorial board member of Neurology and Multiple Sclerosis Journal; receives research support for clinical trials from Sanofi-Aventis, from the Canadian Institutes of Health Research, Research Manitoba, from Multiple Sclerosis Society of Canada and the National Multiple Sclerosis Society, from Multiple Sclerosis Scientific Foundation and from Consortium of Multiple Sclerosis Centers; received research support from the Public Health Agency of Canada.Dr. Yeh perform multiple sclerosis relapse adjudication for ACI services on a fee-for-service basis; serves as an editorial board member of Neurology; receives research support from the Canadian Institutes of Health Research, Patient-Centered Outcomes Research Institute, MS Monitoring system pilot funding, National MS Society, MS Society, Dairy Farmers of Ontario, SickKids Innovation Fund, MS Research Foundation (Canada), and Rare Diseases Foundation.

1) Transient ischemic attack service provision: A review of available service models2) What's Trending: Mediterranean diet and brain structure in a multiethnic elderly cohort3) Topic of the month: Pediatric multiple sclerosis This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Bryan Eckerle interviews Dr. Anna Ranta about her paper on transient ischemic attacks as predictors of high risk for subsequent strokes. Dr. Ted Burns is interviewing Dr. Yian Gu for our "What's Trending" feature of the week about his paper on the Mediterranean diet and brain structure in a multiethnic elderly cohort. In the next part of the podcast Dr. Nick Brenton interviews Dr. Daniela Pohl about the topic of disease-modifying therapy management in pediatric multiple sclerosis. DISCLOSURES: Dr. Ranta receives research support from the New Zealand Health Research Council.Dr. Ted Burns serves as Podcast Editor for Neurology; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Pohl received funding for travel from Teva Pharmaceutical Industries Ltd., Bayer Schering Pharma, ENS, Merck Serono, Consortium of Multiple Sclerosis Center, LACTRIMS and National Multiple Sclerosis Society; received speaker honoraria from Teva Pharmaceutical Industries Ltd., Bayer Schering Pharma, Merck Serono and Consortium of Multiple Sclerosis Center; serves on the scientific advisory board for Biogen Idec and Merck Serono.