Neurology® Podcast

1) Treatment of spinocerebellar ataxia and 2) Topic of the month: Paraneoplastic syndromes in neurology. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Bryan Cupka interviews Dr. Theresa Zesiewicz about her paper on treatment of spinocerebellar ataxia. Dr. Jennifer Fugate is reading our e-Pearl of the week about hereditary angioedema. In the next part of the podcast Dr. Chafic Karam interviews Dr. Josep Dalmau about NMDA encephalitis. Next week, you will hear the last interview by Dr. Karam with Dr. Dalmau about other paraneoplastic syndromes in neurology. The participants had nothing to disclose except Drs. Zesiewicz, Fugate, Karam and Dalmau.Dr. Zesiewicz serves on the speakers' bureau for and has received funding for travel and speaker honoraria from Teva Pharmaceutical Industries Ltd.; serves on the editorial board of Tremor and Other Hyperkinetic Movement Disorders; serves/has served as a consultant for Boehringer Ingelheim, Teva Pharmaceutical Industries Ltd., Allergan, Inc., UCB, and Novartis; is listed as an inventor on a provisional patent on the use of nicotinic modulators in treating ataxia and imbalance held by the University of South Florida; and receives/has received research support from Pfizer Inc, the National Ataxia Foundation, the Friedreich's Ataxia Research Association, and the Bobby Allison Ataxia Research Center.Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Karam serves on the editorial team for the Neurology® Resident and Fellow Section.Dr. Dalmau serves on the editorial board of Neurology®; receives royalties from the editorial board of Up-To-Date; has filed a patent application for the use of LGI1 as a diagnostic test; has received royalties from Athena Diagnostics, Inc. for a patent re: Ma2 autoantibody test and has patents pending re: NMDA and GABAB receptor autoantibody tests (license fee payments received from EUROIMMUN AG); and receives research support from funding from EUROIMMUN AG, the NIH/NCI, and a McKnight Neuroscience of Brain Disorders award.

1) Absent brainstem reflexes and 2) Topic of the month: Paraneoplastic syndromes in neurology. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Shin Chien Beh about his paper on a 41-year-old comatose man. Dr. Jennifer Fugate is reading our e-Pearl of the week about gait freezing. In the next part of the podcast Dr. Chafic Karam interviews Dr. Josep Dalmau about common central nervous system paraneoplastic disorders. Over the next two weeks, Dr. Karam will interview Dr. Dalmau about other paraneoplastic syndromes in neurology. The participants had nothing to disclose except Drs. Burns, Fugate, Karam and Dalmau.Dr. Burns serves as Podcast Editor for Neurology®; performs EMG studies in his neuromuscular practice (30% effort); and has received research support from the Myasthenia Gravis Foundation of America and Knopp Neurosciences Inc..Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Karam serves on the editorial team for the Neurology® Resident and Fellow Section.Dr. Dalmau serves on the editorial board of Neurology®; receives royalties from the editorial board of Up-To-Date; has filed a patent application for the use of LGI1 as a diagnostic test; has received royalties from Athena Diagnostics, Inc. for a patent re: Ma2 autoantibody test and has patents pending re: NMDA and GABAB receptor autoantibody tests (license fee payments received from EUROIMMUN AG); and receives research support from funding from EUROIMMUN AG, the NIH/NCI, and a McKnight Neuroscience of Brain Disorders award.

1) IV thrombolysis-treated ischemic stroke patients and 2) Topic of the month: Paraneoplastic syndromes in neurology. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Brett Kissela interviews Dr. Daniel Strbian about his paper on IV thrombolysis-treated ischemic stroke patients. Dr. Jennifer Fugate is reading our e-Pearl of the week about RRT autoregulation. In the next part of the podcast Dr. Chafic Karam interviews Dr. Josep Dalmau about common paraneoplastic syndromes causing central nervous system disorders. Over the following weeks, Dr. Karam will interview Dr. Dalmau about other paraneoplastic syndromes in neurology. All participants have disclosures.

Evaluation of post-cardiac arrest hypoxic-ischemic encephalopathy. Interview with Eelco Wijdicks.

1) Incidence of MCI subtype differences and 2) Topic of the month: Ethics issues. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Erin Foff interviews Dr. Rosebud Roberts about her paper on the incidence of MCI subtype differences. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about pain in the ear. In the next part of the podcast Dr. Eric Adelman interviews Dr. Michael Russo about requests for medications used for cognitive enhancement. In concluding, there is a brief statement where to find other up-to date patient information and current Patient Page. The participants had nothing to disclose except Drs. Roberts and Clardy.Dr. Roberts receives research support from the NIH and Abbott.Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section.

1) AB load and cognition and 2) Topic of the month: Ethics Issues. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Alberto Espay interviews Dr. Kejal Kantarci about her paper on AB load and cognition in cognitively normal older adults. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about Vespers curse. In the next part of the podcast Dr. Thomas Cochrane interviews Dr. Joseph Fins about neuroimaging in disorders of consciousness. Next week you will hear our last interview regarding ethic issues. The participants had nothing to disclose except Drs. Espay, Kantarci, Clardy, Cochrane and Fins.Dr. Kantarci receives research support from the NIH.Dr. Espay serves on scientific advisory boards for Boehringer Ingelheim and Solvay Pharmaceuticals, Inc.; serves on the editorial advisory board for The European Neurological Journal; has received speaker honoraria from UCB/SCHWARZ PHARMA, Medtronic, Inc., and Novartis; has received honoraria from Novartis, the American Academy of Neurology, and the Movement Disorders Society; has served on speakers' bureaus for UCB/SCHWARZ PHARMA and Novartis; receives/has received research support from Medtronic, Inc., Allergan, Inc., CleveMed, the KL2 Research Scholars mentored career development award, and NIH Institutional Clinical and Translational Science Award (RR026315-02), Dean Scholar's Award - University of Cincinnati, Davis Phinney Foundation, and the Michael J Fox Foundation. Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Cochrane received royalties from the publication of the book First Aid for the Boards: Neurology.Dr. Fins serves as an editorial board member for The Oncologist and The Cambridge Quarterly, received royalties from the publication of the book A Palliative Ethic of Care: Clinical Wisdom at Life's End and serves as President of American Society for Bioethics and Humanities.

1) MuSK myasthenia and 2) Topic of the month: Ethics Issues. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Isabel Illa about her paper on the effect of rituximab in MuSK myasthenia. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about Möbius syndrome. In the next part of the podcast Dr. Nandini Muralidharan interviews Dr. Michael Schneck about conflicting values in withdrawal of support. Over the next two weeks, we will have additional interviews regarding ethic issues. The participants had nothing to disclose except Drs. Burns, Illa, Clardy and Schneck.Dr. Illa has received funding for travel from Genzyme Corporation; serves on the editorial board of Neurologia; is listed as author on patent(s) re: Dysferlin detection in monocytes licensed to Athena Diagnostics, Inc.; and receives research support from Grifols, FIS (Fondo de Investigaciones Sanitarias), ISCIII, Ministry of Health (Spain), and Fundacion Gemio. Dr. Burns serves as Podcast Editor for Neurology®; performs EMG studies in his neuromuscular practice (30% effort); and has received research support from the Myasthenia Gravis Foundation of America and Knopp Neurosciences Inc..Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Schneck serves on data safety monitoring boards for Talecris Biotherapeutics, Chelsea Therapeutics, and Baxter International Inc.; serves on the editorial advisory boards for the Journal of Stroke and Cerebrovascular Disease and Frontiers in Neurocritical Care and Neurohospitalist Care; receives publishing royalties from Continuum; serves on the speakers' bureaus for Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership, Boehringer Ingelheim, and Pfizer Inc; and receives research support from NMT Medical, Schering-Plough Corp., and the NIH.

1) MRI cortical thickness biomarker and 2) Topic of the month: Ethics Issues. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Burns interviews Dr. Brad Dickerson about his paper on the MRI cortical thickness biomarker. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about the empty delta sign. In the next part of the podcast Dr. Alberto Espay interviews Dr. Tony Lang about placebo use for psychgenic disorders. Over the next three weeks, we will have additional interviews regarding ethic issues. The participants had nothing to disclose except Drs. Dickerson, Clardy, Espay and Lang.Dr. Dickerson serves on the editorial board of Hippocampus; serves as a consultant for Pfizer Inc; and receives research support from the NIH and the Alzheimer's Association.Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Espay serves/has served on scientific advisory boards for Boehringer Ingelheim, Solvay Pharmaceuticals, Inc., and Abbott; has received honoraria from Novartis, the American Academy of Neurology, and the Movement Disorders Society; serves on the editorial board of The European Neurological Journal; serves/has served on the speakers' bureaus for Novartis and UCB; and receives/has received research support from Medtronic, Inc., Allergan, Inc., CleveMed, the University of Cincinnati, the Davis Phinney Foundation, and the Michael J Fox Foundation, and is funded by the KL2 Research Scholars mentored career development award, the NIH Institutional Clinical and Translational Science Award (RR026315-02). Dr. Lang has served on scientific advisory boards for Abbott, Allon Therapeutics, Inc., Biovail Corporation, Boerhinger Ingelheim, Cephalon, Inc., Ceregene, Eisai Inc., Medtronic, Inc. Lundbeck Inc., NeuroMolecular Pharmaceuticals , Novartis, Merck Serono, Solvay Pharmaceuticals, Inc., TaroPharma, and Teva Pharmaceutical Industries Ltd.; has received speaker honoraria from GlaxoSmithKline and UCB; receives/has received research support from the Canadian Institutes of Health Research, the Dystonia Medical Research Foundation, the Michael J. Fox Foundation, the National Parkinson Foundation, and the Ontario Problem Gambling Research Centre; and has served as an expert witness in cases related to the welding industry.

1) Hemispatial neglect and 2) Topic of the month: Ethics Issues. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Andy Southerland interviews Dr. Giacomo Koch about his paper on hemispatial neglect. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about the trunk-thigh test of Babinski. In the next part of the podcast Dr. Farrah Mateen interviews Dr. Neelum Aggarwal about emerging issues at the intersection of neurology and applied ethics. Next week, Dr. Espay will interview Dr. Lang about placebo use for psychogenic disorders. The participants had nothing to disclose except Drs. Clardy, Mateen and Aggarwal.Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Mateen served on the editorial team for the Neurology® Resident and Fellow Section from 2006 to 2009. Dr. Aggarwal has served on a scientific advisory board for Pfizer Inc; and receives research support from the NIH and the Alzheimer's Association.

Bedside Testing of the Prefrontal Lobes with interviews with Russ Swerdlow.