1) AB load and cognition and 2) Topic of the month: Ethics Issues. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Alberto Espay interviews Dr. Kejal Kantarci about her paper on AB load and cognition in cognitively normal older adults. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about Vespers curse. In the next part of the podcast Dr. Thomas Cochrane interviews Dr. Joseph Fins about neuroimaging in disorders of consciousness. Next week you will hear our last interview regarding ethic issues. The participants had nothing to disclose except Drs. Espay, Kantarci, Clardy, Cochrane and Fins.Dr. Kantarci receives research support from the NIH.Dr. Espay serves on scientific advisory boards for Boehringer Ingelheim and Solvay Pharmaceuticals, Inc.; serves on the editorial advisory board for The European Neurological Journal; has received speaker honoraria from UCB/SCHWARZ PHARMA, Medtronic, Inc., and Novartis; has received honoraria from Novartis, the American Academy of Neurology, and the Movement Disorders Society; has served on speakers' bureaus for UCB/SCHWARZ PHARMA and Novartis; receives/has received research support from Medtronic, Inc., Allergan, Inc., CleveMed, the KL2 Research Scholars mentored career development award, and NIH Institutional Clinical and Translational Science Award (RR026315-02), Dean Scholar's Award - University of Cincinnati, Davis Phinney Foundation, and the Michael J Fox Foundation. Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Cochrane received royalties from the publication of the book First Aid for the Boards: Neurology.Dr. Fins serves as an editorial board member for The Oncologist and The Cambridge Quarterly, received royalties from the publication of the book A Palliative Ethic of Care: Clinical Wisdom at Life's End and serves as President of American Society for Bioethics and Humanities.