Dr. Jeff Ratliff talks with Dr. Mehari Gebreyohanns, the recipient of the 2025 Ted Burns Humanism in Neurology Award, about his journey into stroke care, the BORNE initiative, and the challenges faced in global neurology. Disclosures can be found at Neurology.org.

The April 2025 replay showcases five compelling physician-as-patient stories. The episode begins with Dr. Franzi Herpich sharing her personal experience of suffering a stroke. It then transitions into a two-part series on arteriovenous malformation, featuring stories from Dr. Joe Sirven and Dr. Amy Hessler. The fourth episode highlights Dr. Eric Seachrist's journey with multiple sclerosis. In the final episode, Dr. Andrea Lendaris discusses her experience with Usher syndrome type 2A and her ongoing battle with acute and chronic health challenges.  Podcast links: Physician as Patient - Stroke  Physicians as Patients Series - Arteriovenous Malformation - Part 1 Physicians as Patients Series - Arteriovenous Malformation - Part 2  Physician as Patient Series - Multiple Sclerosis  Physicians as Patients Series - Inclusivity of Physicians with Disabilities  April 2022 Recall: Physician as Patient  Disclosures can be found at Neurology.org.

Dr. Gordon Smith talks with Dr. Jennifer Morganroth about the increase in thymectomy procedures following the MGTX trial, the differences in access to these surgeries among various demographic groups, and the growing role of minimally invasive surgical techniques. Read the related article in Neurology® Clinical Practice. Disclosures can be found at Neurology.org.

Dr. Andrea Gropman talks with Dr. Stefan Pulst about the significant advancements in Neurology® Genetics over the past decade. Read the related article in Neurology® Genetics.  Disclosures can be found at Neurology.org.

Francesca Puledda, a neurologist from King's College London and author of the International Headache Society's guidelines, shares valuable insights on migraine management. She highlights the importance of tailoring treatment to individual patient needs and regional medication availability. The discussion covers acute treatments like triptans, unique considerations for pregnant women, and the complexities of preventive therapies. Puledda emphasizes a patient-centric approach that balances diverse options with satisfaction, ensuring comprehensive care for migraine sufferers.

Dr. Phillip Ferdinand, a stroke physician at Royal Stoke University Hospital and Keele University, shares insights on the alarming association between smoking and cryptogenic ischemic strokes in young adults. He discusses how smoking intensity correlates with stroke incidence, particularly in males aged 18 to 49. The conversation touches on rising trends in stroke incidents among younger populations and highlights the importance of evaluating social determinants of health. Ferdinand emphasizes the need for tailored prevention strategies and further research into smoking's impact on stroke outcomes.

Timothy Miller, an esteemed neurologist and ALS expert from Washington University, discusses groundbreaking advancements in ALS treatment using Tofersen. He highlights remarkable patient stories, including a patient who experienced a significant recovery after transitioning to the therapy. Miller emphasizes the importance of early intervention, revealing compelling clinical data that showcases promising slowdowns in disease progression. With a focus on shared mechanisms and ongoing research, he fuels optimism for future therapies that could transform ALS into a more treatable condition.

Dr. Amy Brodtmann, director at the Eastern Cognitive Disorders Clinic and professor, joins to discuss the nuances of diagnosing frontotemporal dementia (FTD). She emphasizes the holistic approach needed in assessments, particularly regarding behavioral changes that may mask underlying conditions. The conversation delves into the complexities of distinguishing FTD from Alzheimer's disease and the potential for misdiagnosis. Brodtmann highlights the critical role of follow-up care and emerging blood biomarkers to enhance diagnostic accuracy, shedding light on an often-overlooked area in dementia care.

Dr. Patricia Pozo-Rosich, a leading expert in headache medicine from Valdebron University Hospital, shares insights into groundbreaking advancements in migraine treatment. She emphasizes the importance of early intervention for better patient outcomes and discusses significant studies from 2024 that unveil new therapeutic targets. The conversation also highlights the transformative role of patient feedback and the integration of AI in personalized headache management, while expressing hope for forthcoming treatment innovations.

Dr. Wallace J. Brownlee, a renowned neurologist specializing in multiple sclerosis from Queen Square MS Centre, dives into the evolving landscape of MS diagnosis. He discusses the diminishing focus on dissemination in time (DIT) when high dissemination in space (DIS) criteria are met. The conversation also covers advanced diagnostic techniques like MRI and cerebrospinal fluid analysis. Brownlee outlines the significance of detecting lesions and emphasizes the role of optic neuritis in refining current guidelines for diagnosing relapsing remitting MS.