Dr. Seemant Chaturvedi, a stroke neurology expert from the University of Maryland, shares cutting-edge insights from the International Stroke Conference. He discusses important advancements in stroke treatments, including the role of endovascular therapy and findings from trials such as ESCAPE-MeVO and PRESTIAGE-AF. Chaturvedi also explores the complexities of anticoagulant use post-brain hemorrhage and innovative approaches like transcranial direct current stimulation for recovery. His expert insights emphasize the ongoing evolution of stroke care and research.

Dr. Anne Oaklander, an Associate Professor of Neurology at Harvard, discusses the connection between long COVID and small fiber neuropathy, shedding light on significant diagnostic challenges. She also shares effective management strategies. Dr. Carmel Armon from Loma Linda University tackles the efficacy of epidural steroid injections for spinal issues, presenting mixed results. The conversation highlights the importance of personalized treatment plans and improved research for managing neuropathic pain and conditions like diabetic neuropathy.

Dr. Lorraine Kalia, an associate professor of neurology at the University of Toronto and senior scientist at the Krembil Brain Institute, dives into the intriguing world of GLP-1 receptor agonists as potential treatments for neurodegenerative diseases. She shares insights on the mixed results from recent clinical trials, notably with exenatide, and discusses the promising preclinical benefits such as reduced inflammation. Kalia emphasizes the challenges of translating lab findings to human applications, while pointing to the potential for these therapies in conditions like Parkinson's and Alzheimer's.

Dr. BJ Hicks talks with Dr. Aaron Shoskes about the rising incidence of ischemic stroke in young adults. Read the related article in Neurology®. Disclosures can be found at Neurology.org.

Dr. Carmel Armon, a neurologist at Loma Linda University, discusses the effectiveness of epidural steroid injections in treating cervical and lumbar radicular pain. She emphasizes the contrast between anecdotal evidence and clinical studies, revealing the injections provide limited long-term relief, with modest short-term pain reduction. The conversation highlights the complexities of pain management and the need for further research to clarify treatment outcomes and set realistic patient expectations.

Dr. Gregg Day, a renowned neurologist at Mayo Clinic and co-author of a key paper on brain health, shares insightful strategies for enhancing patients' cognitive well-being. He discusses the innovative Brain Health Initiative and its mnemonic tool 'Safest Brains' to educate clinicians on optimal neurological function. The conversation also touches on the impact of social determinants on neurologic care and the SACO Scholars Program, which fosters brain health education and leadership. This dialogue emphasizes the vital role neurologists play in advocating for comprehensive brain health.

Dr. Shuvro Roy talks with Dr. Giovanna S. Manzano about the management of neurosarcoidosis, highlighting the challenges in diagnosis, treatment approaches, and the importance of collaboration among specialists. Read the related article in Neurology: Clinical Practice. Disclosures can be found at Neurology.org.

Dr. Greg Cooper discusses with Dr. Dean Ornish how lifestyle interventions can significantly enhance cognition and function in patients, providing hope where traditional drug treatments have fallen short. Read the related article in Springer Nature.  Disclosures can be found at Neurology.org. 

Dr. Jeff Ratliff talks with Dr. John W. Winkelman about the new clinical practice guidelines for treating restless legs syndrome and periodic limb movement disorder, covering diagnosis, treatment options, and future management insights. Read the related article in the Journal of Clinical Sleep Medicine. Disclosures can be found at Neurology.org. 

Dr. Greg Cooper talks with Prof. Gill Livingston about new hopeful evidence about dementia prevention, intervention, and care. Read the related article in The Lancet.  Disclosures can be found at Neurology.org.