Journalist and author David Epstein discusses the costs of specialization and the value of breadth in creating mastery. Topics include early specialization in sports, the Polger family's exceptional individuals, the fear of quitting, the importance of trial and error, the Flynn effect, and reflections on writing and career development.

Author, economist, and theologian Mary Hirschfeld of Villanova University talks about her book, Aquinas and the Market, with EconTalk host Russ Roberts. Hirschfeld looks at the nature of our economic activity as buyers and sellers and whether our pursuit of economic growth and material well-being comes at a cost. She encourages a skeptical stance about the ability of more stuff to produce true happiness and/or satisfaction. The conversation includes a critique of economic theory and the aspect of human satisfaction outside the domain of economists.

Neurologist and author Robert Burton talks about his book, On Being Certain, with EconTalk host Russ Roberts. Burton explores our need for certainty and the challenge of being skeptical about what our brain tells us must be true. Where does what Burton calls "the feeling of knowing" come from? Why can memory lead us astray? Burton claims that our reaction to events emerges from competition among different parts of the brain operating below our level of awareness. The conversation includes a discussion of the experience of transcendence and the different ways humans come to that experience.

Poverty activist, social entrepreneur and author, Mauricio Miller, talks about his book The Alternative with EconTalk host Russ Roberts. Miller, a MacArthur genius grant recipient, argues that we have made poverty tolerable when we should be trying to make it more escapable. This is possible, he argues, if we invest in the poor and encourage them to leverage their skills and social networks. Miller emphasizes the importance of self-determination and self-respect as keys to helping the poor improve their own lives.

Economist and author Emily Oster of Brown University talks about her book Cribsheet with EconTalk host Russ Roberts. Oster explores what the data and evidence can tell us about parenting in areas such as breastfeeding, sleep habits, discipline, vaccination, and food allergies. Oster often finds that commonly held views on some of these topics are not well supported by the evidence while on others, the evidence appears decisive. Oster thoughtfully explores the challenges of using empirical work and balances our sometimes ignorance with common sense.

Nobel Laureate Paul Romer of New York University talks with EconTalk host Russ Roberts about the nature of growth, the role of cities in the economy, and the state of economics. Romer also reflects on his time at the World Bank and why he left his position there as Chief Economist.

Historian and author Jill Lepore talks about nationalism, populism, and the state of America with EconTalk host Russ Roberts. Lepore argues that we need a new Americanism, a common story we share and tell ourselves. Along the way, topics in the conversation include populism, the rise of globalization, and the challenge of knowing what is true and what is false in the internet era.

Law professor and author Robin Feldman of UC Hastings College of the Law talks about her book Drugs, Money, and Secret Handshakes with EconTalk host Russ Roberts. Feldman argues that the legal and regulatory environment for drug companies encourages those companies to seek drugs that extend their monopoly through the patent system often with insufficient benefit for consumers. The prices for those drugs are then protected from new competition. She also argues that the pharmacy benefit management system allows drug companies to exploit consumers. The conversation concludes with a discussion of what can be done to improve the situation.

Philosopher and author Jacob Stegenga of the University of Cambridge talks about his book Medical Nihilism with EconTalk host Russ Roberts. Stegenga argues that many medical treatments either fail to achieve their intended goals or achieve those goals with many negative side effects. Stegenga argues that the approval process for pharmaceuticals, for example, exaggerates benefits and underestimates costs. He criticizes the FDA approval process for approving too many drugs that are not sufficiently helpful relative to their side effects. Stegenga argues for a more realistic understanding of what medical practice can and cannot achieve.

Economist and author Daniel Hamermesh of Barnard College and the Institute for the Study of Labor talks about his latest book, Spending Time, with EconTalk host Russ Roberts. Hamermesh explores how we treat time relative to money, how much we work and how that has changed over time, and the ways economists look at time, work, and leisure.