

The Clinical Problem Solvers
The Clinical Problem Solvers
The Clinical Problem Solvers is a multi-modal venture that works to disseminate and democratize the stories and science of diagnostic reasoning
Twitter: @CPSolvers
Website: clinicalproblemsolving.com
Twitter: @CPSolvers
Website: clinicalproblemsolving.com
Episodes
Mentioned books

11 snips
Oct 30, 2025 • 54min
Episode 427: Schema Episode – Schistocytes
A riveting case unfolds with a 65-year-old patient presenting severe dyspnea and anemia. The hosts dissect the diagnostic challenge of schistocytes and pinpoint their role in hemolysis. They navigate through critical lab findings and imaging, uncovering a potential malignancy linked to the patient's condition. Insights on the relationship between adenocarcinoma and hemolytic anemia provide a deeper understanding of marrow infiltration. The case culminates in a treatment response, emphasizing the importance of early diagnosis and lab sensitivity.

Oct 29, 2025 • 1h 3min
Episode 426: Antiracism in Medicine – Episode 29 – Clinician Burnout, Racial Health Inequities & Reincorporating Rest into the Profession
In this discussion, Dr. Kriti Prasad, an internal medicine resident researching clinician burnout, teams up with Dr. Khaalisha Ajala, a hospital medicine professor and founder of A Tribe Called Health. They explore the toll of clinician burnout, emphasizing its links to racial health inequities and moral injury. The conversation reveals how COVID exacerbated these challenges and discusses actionable policy changes needed to support clinician wellbeing. They highlight the importance of reclaiming rest and fostering a healthier medical culture for better patient care.

11 snips
Oct 15, 2025 • 50min
Episode 425: Schema Episode – Ground Glass Opacities
A captivating case of dyspnea with ground-glass opacities unfolds as the hosts tackle diagnostic challenges. They explore the anatomy behind hypoxia and discuss community-acquired pneumonia's diagnostic criteria. Delving into the patient's history reveals bird exposure and potential mold triggers. Discussion shifts to balancing antibiotic use and viral testing amidst exclusion of infections. As the plot thickens, findings lead to a diagnosis of hypersensitivity pneumonitis, with an emphasis on management through exposure removal and ongoing follow-up.

15 snips
Oct 9, 2025 • 49min
Episode 424 – The Clinical Unknown Series with Debora, Mark, Noah and Rabih
In an engaging discussion, the hosts dive into a complex case of a patient facing dizziness and dyspnea. They explore the critical role of anemia in diagnosing symptoms. The team assesses the implications of severe iron deficiency and debates the necessity of transfusions. As they analyze potential causes of occult bleeding, the suspense builds. The revelation of esophageal adenocarcinoma from endoscopic evaluations highlights the challenges in diagnostic medicine. Listeners gain insights into effective clinical reasoning and the importance of thorough investigation.

Oct 7, 2025 • 57min
Episode 423 – RLR – Neutrophilia s/p CABG
https://clinicalproblemsolving.com/wp-content/uploads/2025/10/RLR-PODCAST.mp3Episode descriptionRR discuss a case of AKI Student discounthttps://www.rlrcpsolvers.com/student-discounts/ IMG discountUse coupon code RLRIMG at check out https://rlrcpsolvers.com/annual-plan

31 snips
Oct 2, 2025 • 1h 4min
Episode 422: WDx #38: Clinical Unknown with UCLA Cardiology fellows
Join UCLA Cardiology fellows Dr. Angela Duvalyan and Dr. Rachel Ohman as they dissect a compelling case of a 49-year-old woman with acute chest pain. They navigate through critical differential diagnoses like acute coronary syndrome and the significance of presyncope. The discussion delves into the intriguing findings from the echocardiogram, highlighting hypertrophic cardiomyopathy and its management. The fellows also emphasize the role of cardiac MRI in diagnosing complex cardiac conditions, all while maintaining a focus on patient-centered care.

Sep 18, 2025 • 57min
Episode 421: Baby on Board – and a surprise guest! Listen to Greg and Bobby discuss how to manage the guest tagging along for the ride!!
Greg Kirshen, a maternal-fetal medicine specialist, and Bobby Brar, a fellow in maternal-fetal medicine and clinical genetics, join Anna Jarvis, an OB/GYN resident, to discuss a complex case involving a 10-week pregnant woman with severe abdominal pain and large-volume ascites. They explore differential diagnoses, including infection and malignancy, and share insights on management strategies. The conversation emphasizes the importance of a broad differential and offers practical counseling for future pregnancies.

Sep 15, 2025 • 43min
Episode 420: Antiracism in Medicine – Episode 28 – SGIM 2025: Immigrant and Refugee Health
Masha Slavin, Harita Shah, and Sarah Kimball, experts in immigrant and refugee health, share powerful insights from their diverse backgrounds in medicine. They discuss the impact of racism on healthcare access, highlighting systemic barriers like language and immigration policies. The conversation covers the multifaceted challenges immigrant populations face, emphasizing the importance of culturally sensitive care. They also advocate for community-engaged research and collaboration, aiming to build sustainable partnerships that improve health outcomes for underserved groups.

13 snips
Sep 11, 2025 • 53min
Episode 419: Neurology VMR – Headache and diplopia
Dive into the perplexing world of neurology as experts tackle a case featuring a patient with headaches and diplopia. They explore the intricate connections between neurological symptoms and conditions like rheumatoid arthritis. Key discussions highlight the importance of thorough history-taking, critical lab tests, and innovative diagnostic processes. The conversation also delves into complex treatment decisions surrounding autoimmune disorders, ensuring an informative blend of patient care and medical reasoning. Perfect for anyone intrigued by the mysteries of the brain!

10 snips
Sep 10, 2025 • 27min
Episode 418 – #IDLove – Colitis
Delve into the complexities of diagnosing diarrhea in young adults, weighing infectious versus non-infectious causes. Discover the intricacies of travel-related diseases through a patient's case from Bogota. The conversation highlights how gastrointestinal issues can stem from various pathogens post-travel. A deep dive into differential diagnoses emphasizes the critical role of lab results. The session kicks off with a compelling case study of a young man's gastrointestinal symptoms, blending clinical reasoning with real-world scenarios.


