

The Clinical Problem Solvers
The Clinical Problem Solvers
The Clinical Problem Solvers is a multi-modal venture that works to disseminate and democratize the stories and science of diagnostic reasoning
Twitter: @CPSolvers
Website: clinicalproblemsolving.com
Twitter: @CPSolvers
Website: clinicalproblemsolving.com
Episodes
Mentioned books

Sep 11, 2025 • 53min
Episode 419: Neurology VMR – Headache and diplopia
Dive into the perplexing world of neurology as experts tackle a case featuring a patient with headaches and diplopia. They explore the intricate connections between neurological symptoms and conditions like rheumatoid arthritis. Key discussions highlight the importance of thorough history-taking, critical lab tests, and innovative diagnostic processes. The conversation also delves into complex treatment decisions surrounding autoimmune disorders, ensuring an informative blend of patient care and medical reasoning. Perfect for anyone intrigued by the mysteries of the brain!

10 snips
Sep 10, 2025 • 27min
Episode 418 – #IDLove – Colitis
Delve into the complexities of diagnosing diarrhea in young adults, weighing infectious versus non-infectious causes. Discover the intricacies of travel-related diseases through a patient's case from Bogota. The conversation highlights how gastrointestinal issues can stem from various pathogens post-travel. A deep dive into differential diagnoses emphasizes the critical role of lab results. The session kicks off with a compelling case study of a young man's gastrointestinal symptoms, blending clinical reasoning with real-world scenarios.

5 snips
Sep 1, 2025 • 54min
Episode 417 – RLR – A unique AKI
Join a lively conversation that starts with birthday celebrations and transitions into the complexities of Meg's syndrome, a benign mimic of metastatic cancer. The hosts tackle the tricky waters between acute kidney injury and chronic kidney disease, using illustrative cases to highlight diagnostic challenges. A detailed case study on bilateral hydronephrosis showcases the importance of imaging and clinical intuition. Finally, the discussion takes twists to connect renal issues with broader organ dysfunction, revealing critical health insights.

Aug 29, 2025 • 51min
Episode 416 – Clinical Unknown Series with Dr. Vinicius de Sousa
A middle-aged man with a troubling bilateral rash takes center stage in a captivating clinical analysis. The discussion dives deep into the complexities of diagnosing dermatological conditions, highlighting potential small vessel vasculitis. Listeners will appreciate the emphasis on systematic approaches to patient evaluation, the nitty-gritty of lab findings, and how important differential diagnoses can be. Alongside serious medical talk, the light-hearted vibe of music preferences adds a unique flavor, making learning both engaging and informative.

15 snips
Aug 27, 2025 • 57min
Episode 415 – Spaced Learning Series – Beyond The Coagulation Cascade
Dive into the world of coagulation as the hosts tackle a complex case of a 70-year-old man facing unusual bleeding. They dissect the nuances of hemostasis, addressing the key roles of blood components and the implications of coagulopathy. Lab findings related to leukocytosis and kidney issues are explored, emphasizing accurate diagnoses. The challenges of amyloidosis and vascular health are discussed, shedding light on the intricate relationship between conditions and bleeding risks. An interdisciplinary approach to treatment highlights the complexities of managing such cases.

9 snips
Aug 19, 2025 • 35min
Episode 414: Spaced Learning Series, dysuria
Join the discussion as the hosts dive into a clinical case about a 62-year-old patient experiencing dysuria. They share personal insights and highlight the significance of thorough clinical assessments. The importance of distinguishing between infectious and non-infectious causes is emphasized, along with the challenges of diagnosing persistent symptoms. Evaluations of laboratory results and urine analysis bring to light critical factors in treatment. The episode also tackles the complexities of urological issues and innovative management strategies.

Aug 15, 2025 • 44min
Episode 413: Rafael Medina Hepatology Episode with Dr. Tapper – Driver or Bystander
Elliot Tapper is an Associate Professor in Gastroenterology and Hepatology at the University of Michigan, while Hirsh Elhence is an Internal Medicine resident at the University of Colorado with a keen interest in hepatology. They explore whether the liver is a driver of health issues or merely a bystander. Key topics include navigating liver transplant evaluations, distinguishing between acute liver injury and acute liver failure, and unraveling complex liver cases. Their engaging dialogue emphasizes patient-centered care and the importance of detailed medical assessment.

17 snips
Aug 7, 2025 • 42min
Episode 412: Schema Episode – Seizure, Fever, Encephalopathy
Dive into an intriguing clinical case featuring a 54-year-old male with new-onset seizures and fever. The team explores critical diagnostic challenges and management strategies, particularly in the context of severe hypoxia and neurocritical care. Discussions illuminate the complexities of diagnosing CNS diseases, including meningoencephalitis and cryptococcal infections. Personal anecdotes about favorite shows and emotional milestones add a light-hearted touch to the intense medical insights, making for both an entertaining and educational experience.

7 snips
Aug 4, 2025 • 30min
Episode 411 – RLR – Abrupt Abdominal Pain
Dive into the complexities of abrupt abdominal pain, including hilarious medical mix-ups and critical assessment strategies. Learn about Eisenmenger syndrome and its connection to congenital heart defects. Explore the urgent management techniques for severe abdominal cases, highlighting the importance of timely imaging and intervention. The podcast also tackles the rising incidence of colon cancer in younger patients and the intriguing connections between recurrent intussusception and cannabinoid hyperemesis syndrome, emphasizing thorough clinical reasoning.

Jul 31, 2025 • 54min
Episode 410: Neurology VMR – right hand weakness for 3 months
Join neurologist Aaron Berkowitz and medical graduate Aye Chan Moe Thant as they delve into a fascinating case of a 19-year-old with persistent right-hand weakness. Aye shares her inspiring journey from Myanmar, advocating for health equity while analyzing neurological causes of the patient's symptoms. They explore critical topics like brachial plexus functions, diagnostic techniques, and the intrigued implications of rare conditions like Hirayama disease. Tune in for a captivating discussion that demystifies neurology and promotes understanding!