

The Clinical Problem Solvers
The Clinical Problem Solvers
The Clinical Problem Solvers is a multi-modal venture that works to disseminate and democratize the stories and science of diagnostic reasoning
Twitter: @CPSolvers
Website: clinicalproblemsolving.com
Twitter: @CPSolvers
Website: clinicalproblemsolving.com
Episodes
Mentioned books

Dec 11, 2025 • 57min
Episode 434: Schema Episode – Eosinophilia
https://clinicalproblemsolving.com/wp-content/uploads/2025/12/Schema_12_10_15.mp3Noah presents a fascinating case involving eosinophilia. Tune in as Maddy, Mark, and Youssef work through the diagnostic puzzle.To join us live on Virtual Morning Report (VMR), sign up HERE.Download CPSolvers App hereRLRCPSOLVERS

Dec 2, 2025 • 38min
Episode 433 – RLR – A Red Leg
https://clinicalproblemsolving.com/wp-content/uploads/2025/12/Case-158-1.mp3Episodic descriptionRLR discussed a case of a red leg Student discounthttps://www.rlrcpsolvers.com/student-discounts/ IMG discountUse coupon code RLRIMG at check out https://rlrcpsolvers.com/annual-plan

Dec 2, 2025 • 38min
Episode 432 – Spaced Learning Series – subacute inflammation
https://clinicalproblemsolving.com/wp-content/uploads/2025/12/MORAD-SLS-2.mp3 Download CPSolvers App hereRLR CPSolvers In this new SLS episode, Maryana presents a case to Austin, Oumaima, and David as they navigate the waves of subacute inflammation and abdominal pain.

Nov 21, 2025 • 1h 1min
Episode 431: The Clinical Unknown Series with Anmolpreet Kaur
Anmolpreet Kaur, a clinician specializing in diagnostic reasoning, joins Mark for an engaging case discussion. They tackle a complex scenario involving a 71-year-old patient with altered mental status and delve into the MIST framework for diagnostics. Highlights include the importance of time course in symptoms, managing severe electrolyte imbalances, and interpreting symptoms tied to pneumonia and brain conditions. The conversation culminates in diagnosing glioblastoma and an MRSA lung abscess, illustrating the intricate connections within complex medical cases.

10 snips
Nov 13, 2025 • 59min
Episode 430: WDx #39: Clinical Unknown with Drs. Kuchal Agadi and Ann Marie Kumfer
Dr. Ann Marie Kumfer, a North Carolina hospitalist, and Dr. Kuchal Agadi, an internal medicine resident, delve into a complex case of a ventilated young man suffering from fever and empyema. Ann Marie shares insights on assessing infection sources in nonverbal patients, while Kuchal presents alarming lab results such as severe anemia and loculated effusion. The duo discusses the challenges of antibiotic stewardship and the importance of timely drainage in empyema management, revealing final microbiology findings like Achromobacter and Pseudomonas.

Nov 5, 2025 • 25min
Episode 429 – RLR – Forehead Bump
Hosts exchange humorous anecdotes and dive into a fascinating clinical case involving a patient with a forehead mass. They discuss the diagnostic process, revealing CT findings that suggest osteomyelitis. The conversation shifts to exploring potential infectious causes, highlighting the importance of thorough testing. The surprising diagnosis of secondary syphilis as the culprit for skull osteomyelitis underlines the need for clinical reasoning in rare cases. A mix of levity and serious medical insight makes for an engaging discussion.

Nov 2, 2025 • 59min
Episode 428: Neurology VMR – Diplopia and fever
Dr. Yousuf Patel, a neurology resident from Cape Town with diverse medical training, presents a compelling case of diplopia and fever. He dives into distinguishing types of diplopia and the crucial role of the medial longitudinal fasciculus in gaze coordination. The discussion uncovers potential infectious causes linking fever with diplopia, addressing key diagnostic elements. A surprising link to Behçet's syndrome emerges through patient history and MRI findings, showcasing the importance of a thorough examination in uncovering complex neurological disorders.

10 snips
Oct 30, 2025 • 54min
Episode 427: Schema Episode – Schistocytes
A riveting case unfolds with a 65-year-old patient presenting severe dyspnea and anemia. The hosts dissect the diagnostic challenge of schistocytes and pinpoint their role in hemolysis. They navigate through critical lab findings and imaging, uncovering a potential malignancy linked to the patient's condition. Insights on the relationship between adenocarcinoma and hemolytic anemia provide a deeper understanding of marrow infiltration. The case culminates in a treatment response, emphasizing the importance of early diagnosis and lab sensitivity.

Oct 29, 2025 • 1h 3min
Episode 426: Antiracism in Medicine – Episode 29 – Clinician Burnout, Racial Health Inequities & Reincorporating Rest into the Profession
In this discussion, Dr. Kriti Prasad, an internal medicine resident researching clinician burnout, teams up with Dr. Khaalisha Ajala, a hospital medicine professor and founder of A Tribe Called Health. They explore the toll of clinician burnout, emphasizing its links to racial health inequities and moral injury. The conversation reveals how COVID exacerbated these challenges and discusses actionable policy changes needed to support clinician wellbeing. They highlight the importance of reclaiming rest and fostering a healthier medical culture for better patient care.

11 snips
Oct 15, 2025 • 50min
Episode 425: Schema Episode – Ground Glass Opacities
A captivating case of dyspnea with ground-glass opacities unfolds as the hosts tackle diagnostic challenges. They explore the anatomy behind hypoxia and discuss community-acquired pneumonia's diagnostic criteria. Delving into the patient's history reveals bird exposure and potential mold triggers. Discussion shifts to balancing antibiotic use and viral testing amidst exclusion of infections. As the plot thickens, findings lead to a diagnosis of hypersensitivity pneumonitis, with an emphasis on management through exposure removal and ongoing follow-up.


