
The Clinical Problem Solvers
The Clinical Problem Solvers is a multi-modal venture that works to disseminate and democratize the stories and science of diagnostic reasoning
Twitter: @CPSolvers
Website: clinicalproblemsolving.com
Latest episodes

Jun 2, 2025 • 44min
Episode – 399 – RLR – Ascites
The hosts share amusing pet anecdotes, setting a light conversational tone. They dive deep into ascites and chylous effusion, discussing fluid analysis methods. A case study features a 64-year-old man with bilateral hydronephrosis, exploring complex differential diagnoses. The critical evaluation of a chest x-ray reveals intriguing connections to heart and lymphatic issues. They also tackle a challenging case with idiopathic ureteral stenosis, highlighting the importance of teamwork and open dialogue among medical professionals.

May 29, 2025 • 47min
Episode 398: WDx #36: How to Approach a “Struggling” Learner
Dr. Julia Armendariz, a hospitalist and clinician educator at Stanford, shares her expertise on guiding struggling learners in medical education. She emphasizes the power of low-inference statements in feedback, helping to pinpoint underlying issues. The conversation highlights the need for empathy and clear communication, advocating for a compassionate approach. Julia also discusses the challenges of delivering feedback amidst emotional complexities, revealing strategies to support both high and low insight learners effectively.

35 snips
May 22, 2025 • 59min
Episode 397: Rafael Medina Subspecialty Episode – Hypertension in Pregnancy
Dr. Greg Kirschen, a Maternal-Fetal Medicine fellow at the Hospital of the University of Pennsylvania, and Dr. Mary Peeler, a fellow at UNC, dive deep into hypertension in pregnancy. They discuss a compelling case involving a pregnant woman with headaches and blurry vision, underscoring the risks of preeclampsia. Insights include essential lab tests for diagnosis, the significance of blood pressure control, and the protective role of medications like magnesium. The duo emphasizes addressing health disparities and the collaborative approach necessary for optimal patient care.

May 16, 2025 • 29min
Episode 396: Schema Episode – Hypercarbia
Andrew Sanchez, a clinical expert, shares a compelling case of a woman facing progressive dyspnea and hypercarbia. The discussion dives deep into obesity hypoventilation syndrome, evaluating the physiological factors leading to her respiratory distress. The team emphasizes the significance of thorough diagnostics, including the interpretation of chest X-rays. They also explore mixed respiratory failure exacerbated by heart failure, showcasing the critical connection between respiratory issues and obesity in treatment outcomes.

May 9, 2025 • 55min
Episode 395: Neurology VMR – Behavior change, headaches, and blurry vision
Aye Chan Moe Thant, a medical graduate from Myanmar, joins the discussion to present a challenging case of a 51-year-old woman with behavioral changes, headaches, and blurry vision. They delve into diagnosing complex neuroimmune disorders and explore potential diagnoses like hydrocephalus and encephalitis. The conversation highlights the role of environmental factors and intra-cranial pressure symptoms, emphasizing the importance of thorough clinical evaluations and imaging. Aye's commitment to health equity adds a powerful dimension to the medical intricacies discussed.

12 snips
May 6, 2025 • 39min
Episode 394 – RLR – Rapid Response
Family gatherings take a comical twist when age-related antics lead to playful banter. Discover how AI is revolutionizing nutritional tracking, helping people meet their dietary goals. The speakers share gripping insights into navigating emergency medical situations, emphasizing observation and communication. A real chest pain case illustrates the vital role of patient engagement and rapid testing. Lastly, the importance of CT pulmonary angiograms is highlighted, challenging myths about their cost and necessity in urgent care.

24 snips
May 1, 2025 • 35min
Episode 393 – Spaced Learning Series – Hyperglycemia
Dive into a gripping case of hyperglycemia that might hide something more sinister. The hosts dissect a 65-year-old patient’s alarming symptoms, linking them to potential pancreatic cancer risks. They tackle diagnostic nuances like insulin resistance and the complexities of lab results, including the dangers of hypokalemia. Personal anecdotes and sharp medical insights illuminate the discussion, while the importance of early diagnosis and thorough patient history is emphasized throughout.

Apr 25, 2025 • 49min
Episode 392: Antiracism in Medicine – Episode 27 – Racial and Gender Health Disparities in Youth Suicide: Part 2
Dr. Tami Benton, a leading psychiatrist at the Children’s Hospital of Philadelphia, and Dr. Kevin Simon, Boston’s inaugural Chief Behavioral Health Officer, dive into the alarming rise of youth suicide rates among Black girls. They discuss the unique mental health challenges these communities face, emphasizing the need for culturally grounded support and advocacy. The conversation highlights the importance of community involvement, addressing access barriers, and the necessity of cultural humility in mental health care to bridge existing disparities.

Apr 25, 2025 • 59min
Episode 391: Clinical Unknown Series with Marcela Santana
In this discussion, Marcela Santana, a second-year resident at WashU and close friend of Noah, dives into a riveting clinical case presented by Debora. They dissect the challenges of diagnosing a 36-year-old woman suffering from right upper quadrant pain and post-operative complications following cholecystectomy. The conversation highlights the importance of differential diagnosis and a thorough evaluation. With engaging anecdotes and clinical insights, they emphasize collaborative assessment, especially when navigating complexities like neutropenic fever and discordant lab results.

Apr 16, 2025 • 53min
Episode 390: WDx #35: Demystifying Feedback
Dr. Julia Armendariz, a hospitalist and clinician educator, shares her passion for feedback in medical education. She emphasizes the critical role of constructive criticism and goal-setting among learners. Julia debunks common myths about feedback and highlights strategies for creating a positive team environment. She discusses the importance of timely feedback in fostering growth and explores how to establish a feedback culture in personal relationships. Her insights shed light on mentorship, collaboration, and the joys and challenges in medical education.