
Flex Diet Podcast
Dr. Mike T Nelson gets geeky with the latest research and scientific findings in the fitness world. Visit www.flexdiet.com to get Flex Diet Certified and www.miketnelson.com for more geeky goodness.
Latest episodes

Jun 2, 2025 • 51min
Episode 327: Flexible Meathead Cardio: Barbell Shrugged Rebroadcast with Dr Mike T Nelson
Welcome back to the Flex Diet Podcast! I’m your host, Dr. Mike T. Nelson, and today’s episode is a special rebroadcast of a conversation I had on the Barbell Shrugged podcast with Anders Varner. We dive deep into what I call the Flexible Meathead Cardio Approach — a method designed specifically for strength athletes and lifters who know they need cardio but don’t want it to kill their gains.In this episode, I break down how to build a cardio plan that enhances, not competes with, your strength and performance goals. We cover why aerobic conditioning is a secret weapon for recovery, how it helps you train harder over time, and how to structure your week for maximum benefit.We also get into the weeds on VO2 max testing, different cardio modalities (and when to use them), and how to leverage health data from wearables like the Oura Ring for smarter training decisions. If you’re a lifter who wants to be strong and fit without living on a treadmill, this one’s for you.Sponsors:Tecton Life Ketone drink! https://tectonlife.com/ DRMIKE to save 20%LMNT electrolyte drink mix: miketnelsonlmnt.comFexible Meathead Cardio Level 1: Sign-up hereAvailable now:Grab a copy of the Triphasic Training II book I co-wrote with Cal Deitz here.Episode Chapters:00:35 Flexible Meathead Cardio Approach00:55 Enrollment Details for the Cardio Course01:45 Podcast Collaboration and Disclosure02:08 Introduction to the Barbell Shrugged Episode02:12 Cardio for Strength Training Enthusiasts05:28 Benefits of Aerobic Training for Lifters09:51 Personal Experience and Data Insights22:58 Structuring Cardio for Muscle-Bound Athletes27:49 Interval Training and Output Management29:03 Recovery Strategies for Intervals31:08 High-Intensity Intervals vs. Long Runs33:41 Understanding VO2 Max Testing39:04 VO2 Max Standards and Goals45:32 Structuring a Balanced Training Week47:46 The Importance of Consistent Cardio49:36 Conclusion and Where to Find More InformationFlex Diet Podcast Episodes You May Enjoy:Episode 287: Insights and Innovations in HRV and Aerobic Training with Coach Joel JamiesonEpisode 138: Why Everyone Benefits from Aerobic Training – Even MeatheadsGet In Touch with Dr Mike:Instagram: DrmiketnelsonYouTube: @flexdietcertEmail: Miketnelson.com/contact-us

May 26, 2025 • 1h 29min
Episode 326: Row Hard, Breathe Easy: Boosting Aerobic Capacity with Dr. Kenneth Jay
Welcome back to the Flex Diet Podcast! I’m your host, Dr. Mike T. Nelson, and in this episode, I sit down with my good friend Dr. Kenneth Jay, a PhD in Physiology and Biomechanics, coach to Olympic-level athletes, and creator of the Row Forge app.We go deep on all things cardiovascular performance, especially how to improve aerobic capacity without losing your hard-earned strength. You’ll hear us geek out over the Concept2 rower (yes, it’s a love-hate relationship), and dig into the science of rowing mechanics, training protocols, and how to crush your 2k time, including Kenneth’s brutal but effective “Mjolnir” workout.We also cover key concepts like VO2 max, zone two training, and when to use HIIT vs. steady-state cardio. Whether you’re a strength athlete trying to up your conditioning game or just looking to improve overall performance, there’s something here for you.We even touch on practical tools like ketone esters, electrolytes, and how to maintain conditioning without burning out.Sponsors:Tecton Life Ketone drink! https://tectonlife.com/ DRMIKE to save 20%LMNT electrolyte drink mix: miketnelsonlmnt.comDaily Fitness Insider Newsletter: https://flex-diet.kit.com/bfa1510fa8Triphasic 2 book now available!Go to https://triphasic2.com/Episode Chapters:02:28 The Benefits of Rowing for Cardiovascular Performance02:59 Deep Dive into Rowing and Cardiovascular Training15:51 Rowing Protocols and Training Tips39:08 VO2 Max and Rowing Assessments47:27 Aerobic Base and Specialized Training48:14 Individual Differences in 2K Times49:05 Case Study: Brutal Training Regimen51:35 Concept2 Logbook and Performance Metrics54:05 Effective Rowing Protocols56:06 The Mjolnir Protocol01:05:32 Zone 2 Training and Maintenance01:22:17 Rowforge App and Final Thoughts Flex Diet Podcast Episodes You May Enjoy: Episode 287: Insights and Innovations in HRV and Aerobic Training with Coach Joel Jamieson Episode 138: Why Everyone Benefits from Aerobic Training – Even MeatheadsConnect with Dr Kenneth Jay: Instagram: https://www.instagram.com/drkennethjay/YouTube: https://www.youtube.com/playlist?list=PLxblf7cM-gVol9BLLOxfoI0jv-vzFsl5OGet In Touch with Dr Mike:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpg

May 19, 2025 • 1h 45min
Episode 325: The Uncommon Science of Cold: Brown Fat, Resilience & Recovery with Dr. Thomas Seager
Welcome back to the Flex Diet Podcast. I'm Dr. Mike T. Nelson, and today I’m diving into the frigid but fascinating world of cold water immersion with Dr. Thomas P. Seeger — a true pioneer in sustainable engineering and a leading voice on cold exposure.We break down the latest science behind cold plunges, including how they impact brown fat, metabolism, HRV, testosterone and overall resilience. Tom also shares key takeaways from his excellent book Uncommon Cold, and gives us a peek into the thinking behind his company, Morozko Forge — makers of some seriously high-tech cold tubs.We even get into my own experiences with cold immersion, what’s hype and what’s helpful, and how to safely integrate it into your routine for health and performance gains.Sponsors:Tecton Life Ketone drink! https://tectonlife.com/ DRMIKE to save 20%LMNT electrolyte drink mix: miketnelsonlmnt.comDaily Fitness Insider Newsletter: https://flex-diet.kit.com/bfa1510fa8Triphasic 2 book now available!Go to https://triphasic2.com/Episode Chapters:05:09 Welcome Dr. Tom: Cold Plunge Setup06:20 The Science Behind Cold Plunges07:13 Physiological Responses to Cold Exposure17:00 Brown Fat and Metabolic Health26:48 Psychological Resilience and Cold Exposure49:12 Heart Rate Variability and Cold Immersion52:43 Starting a Cold Water Immersion Routine55:53 Psychological Tricks and Cold Exposure56:29 Individual Differences in Cold Tolerance57:43 Optimal Time and Temperature: A Myth58:07 Cold Training vs. Medical Fallacies01:02:33 Testosterone and Cold Exposure01:05:59 The Uncommon Testosterone Book01:11:53 TRT and Natural Alternatives01:19:37 Personal Experiences and Recommendations01:26:07 Morozko Forge: The Ultimate Ice Bath01:34:47 Final Thoughts and Recommendations Flex Diet Podcast Episodes You May Enjoy: Episode 202: Cold water immersion and the body’s regulation systems: An interview with Dr. Dwayne Jackson Episode 114: How To Be More Robust and Antifragile with Cold Water Immersion and Sauna: The Barbell Model of Phys FlexConnect with Dr Seager: Instagram: https://www.instagram.com/seagertpMorozko Forge: https://www.morozkoforge.com/Uncommon Cold: https://www.morozkoforge.com/post/uncommon-cold-bookGet In Touch with Dr Mike:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpg

May 13, 2025 • 57min
Episode 324: Exploring Microdosing: Benefits, Research, and Personal Experiences
In this episode of the Flex Diet Podcast, I sit down with Dr. James Fadiman and Jordan Gruber to talk all things microdosing—what it is, what it isn’t, and why it’s gaining so much traction in health, performance and even mental clarity.We dig into their new book, Microdosing for Healing, Health, and Enhanced Performance, and cover everything from the history of psychedelics to the latest research and how people are using tiny doses of these compounds to potentially improve cognitive function, mood and physical performance.We also talk about personal experience—what they’ve seen, what they’ve felt, and what they’ve learned along the way. Of course, none of this is medical advice. These substances still live in legal gray zones depending on where you are, so proceed with caution and do your homework.If you’re curious about the science and the real-world implications of microdosing, this episode is a must-listen. Let’s get into it.Sponsors:Daily Fitness Insider Newsletter: https://flex-diet.kit.com/bfa1510fa8Triphasic 2 book now available!Go to https://triphasic2.com/Episode Chapters:01:07 Exploring Microdosing: Benefits and Research01:56 Legal and Safety Considerations02:45 Personal Experiences with Psychedelics04:05 Microdosing Protocols and Effects17:13 Microdosing for Enhanced Performance29:22 The Role of Coaching in Neuroplasticity29:40 Microdosing and Moral Implications30:20 Understanding Neuroplasticity with Psychedelics34:06 Microdosing for Chronic Pain34:58 Microdosing vs. Pharmaceuticals36:54 Real-Life Evidence and Research47:43 Potential Risks of Microdosing51:51 Microdosing Community and Resources54:23 Conclusion and Final ThoughtsFlex Diet Podcast Episodes You May Enjoy: Episode 162: Aaron Rodgers ayahuasca retreat, performance, and research – a solocast by Dr Mike T Nelson Episode 111: My Plant Medicine Experience w Ayahuasca and Kambo in Costa RicaConnect with : Microdosing for Health, Healing and Advanced Performance: https://www.amazon.com/Microdosing-Health-Healing-Enhanced-Performance/dp/1250355583Dr James Fadiman: https://www.jamesfadiman.com/Jordan Gruber: https://jordangruber.com/Get In Touch with Dr Mike:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpg

May 5, 2025 • 1h 10min
Episode 323: Natural vs. Enhanced Bodybuilding: An In-Depth Chat with Aaron Straker
In this episode of the Flex Diet Podcast, I sit down with Aaron Straker for a deep dive into his journey from natural bodybuilding to the enhanced side of the sport. We talk openly about the trade-offs, risks, and insights he's gained along the way—including the use of compounds like testosterone and growth hormone.We also get into the mental and physical shifts that come with that transition, and how Aaron approaches training, nutrition, and recovery with intention. He shares his thoughts on everything from sauna use to how he stays grounded while optimizing performance. Whether you're just curious or seriously considering the enhanced route, this episode offers a nuanced, no-BS perspective.Sponsors:Tecton Life Ketone drink! https://tectonlife.com/ DRMIKE to save 20%LMNT electrolyte drink mix: miketnelsonlmnt.comDaily Fitness Insider Newsletter: https://flex-diet.kit.com/bfa1510fa8Flex 4: Aaron's top 4 factors to consider before starting TRT or PEDsTriphasic 2 book now available!Go to https://triphasic2.com/Episode Chapters:06:01 Aaron's Life in Bali10:33 Natural vs Enhanced Bodybuilding17:13 Aaron's Journey and Training Insights34:40 Health Concerns and Blood Pressure Monitoring35:36 Mind-Muscle Connection and Nervous System Effects38:30 Diet and Macros During Training Phases42:07 Challenges of High-Calorie Diets43:29 PEDs and Their Impact on Training and Recovery51:51 Sauna Use and Recovery Protocols56:35 Individual Responses to PEDs59:14 Mental and Emotional Effects of PEDs01:04:37 Podcast Conclusion and Final ThoughtsFlex Diet Podcast Episodes You May Enjoy: Episode 216: Building a successful online fitness coaching business: An Interview with Aaron Straker Episode 185: Are more top bodybuilders dying early? Extreme bodybuilding methods – risks and rewards: a conversation w/ Dr Guillermo EscalanteConnect with Aaron: Instagram: https://www.instagram.com/aaron_strakerPodcast: https://www.eattrainprosper.com/Website: https://strakernutritionco.com/coaching-services/Get In Touch with Dr Mike:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpg

May 2, 2025 • 56min
Episode 322: BONUS Iron Radio Cold Water & MPS, Mind in Muscle
In this episode of Iron Radio, hosts Coach Phil Stevens, Dr. Mike Nelson, Coach Jerell, and Dr. Lonnie Lowery discuss recent studies on the impact of cold water immersion on muscle protein synthesis and recovery. Dr. Nelson shares insights from a study published in March 2025, examining how post-exercise cooling affects blood flow and amino acid incorporation into muscle tissue. The team debates the pros and cons of cold water immersion, particularly for muscle hypertrophy and recovery, and shares personal experiences and practical applications. Later, they delve into the mind-muscle connection, exploring its use in both bodybuilding and strength training, and how to effectively incorporate this technique into workouts. The conversation wraps up with a discussion on posing in bodybuilding and how internal and external cues affect performance.Episode Chapters:01:16 Muscle Protein Synthesis and Cold Water Immersion08:18 Practical Applications and Public Perception22:53 Iron Radio Updates and Announcements25:16 Mind-Muscle Connection: Bodybuilders vs. Athletes31:08 Effective Rowing Techniques31:48 The Importance of Slowing Down35:21 Mind-Muscle Connection39:11 Neural Reeducation Insights46:01 Practical Tips for Strength Athletes51:26 Posing and Performance in BodybuildingDonate to the show via PayPal HERE.You can also join Dr Mike's Insider Newsletter for more info on how to add muscle, improve your performance and body comp - all without destroying your health, go to www.ironradiodrmike.com Thank you!Phil, Jerrell, Mike T, and Lonnie

Apr 28, 2025 • 58min
Episode 321: Optimizing Fat Loss and Muscle with Dr. Mike Ormsbee
Welcome back to the Flex Diet Podcast. I’m Dr. Mike T. Nelson, and today I’m joined by my good friend and colleague, Dr. Mike Ormsbee. We’re digging deep into how to optimize metabolism using strategies from the Flex Diet Certification, as well as why both aerobic and resistance training are crucial for long-term success.We also delve into some advanced topics, such as how growth hormone and lipolysis contribute to effective fat utilization, and how cutting-edge techniques like microdialysis enable us to study metabolism at a local level. Along the way, we hit on key concepts like fat metabolism, body composition changes, and even how evening eating affects the process.We’ll share insights from some of the studies we’re working on now, and why combining resistance training with smart nutrition could be the game-changer you’re looking for. Hope you enjoy this deep dive into the science (and practice) of fitness and health!Sponsors:Tecton Life Ketone drink! https://tectonlife.com/ DRMIKE to save 20%LMNT electrolyte drink mix: miketnelsonlmnt.comDaily Fitness Insider Newsletter: https://flex-diet.kit.com/bfa1510fa8Flex 4: Dr Ormsbee's top four things to do to maximize fat lossTriphasic 2 book now available!Go to https://triphasic2.com/Episode Chapters:03:07 Informal Conversation Kickoff05:22 Academia and Personal Branding07:08 Cardio for Meatheads09:01 Resistance Training and Fat Metabolism17:26 Body Composition Studies27:02 Obesity and Exercise Response29:04 Exploring Alpha Receptors and Him Buying29:32 Resistance Training and Obesity30:33 Growth Hormone and Insulin Responses31:23 Body Fat and Athletic Performance32:00 Triathletes and Body Fat Analysis32:52 Resistance Training vs. Aerobic Training33:07 NIH Grant and Current Study33:28 Lipolysis and Fat Loss Mechanisms35:43 Muscle and Fat Tissue Communication37:35 Resistance Training and Fat Loss43:11 Eating in the Evening: Myths and Facts46:23 Protein Intake and Sleep51:00 Future Research Directions52:45 Conclusion and Final Thoughts.Flex Diet Podcast Episodes You May Enjoy: Episode 209: How to achieve your fat loss goals while not overly restrictive: an interview with the author of “You Can’t Screw This Up,” Adam BornsteinEpisode 173: High-Level Nutrition and Programming for Fat Loss: Dr. Pat Davidson with Dr. Mike T NelsonConnect with Dr. Ormsbee: Instagram: https://www.instagram.com/mikeormsbeeCourse: https://www.thegreatcoursesplus.com/changing-body-composition-through-diet-and-exerciseInstitute of Sports Science and Medicine: https://annescollege.fsu.edu/resources/institute-sports-sciences-and-medicineGet In Touch with Dr Mike:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpgEmail: https://miketnelson.com/contact-us/

Apr 21, 2025 • 58min
Episode 320: Unlocking Mitochondrial Secrets with Dr. Hemal Patel
Welcome back to the Flex Diet Podcast! I’m Dr. Mike T. Nelson, and in this episode, I sit down with Dr. Hemal Patel, Chief Scientific Advisor to Discovery and the brilliant mind behind the ME screen blood test for mitochondrial function.We dive into Dr. Patel’s fascinating journey into the world of mitochondrial research, how mitochondria impact everything from metabolism to resilience, and why he developed a personalized blood test to better understand mitochondrial health. We also get into some really cool topics like how heat and cold exposure affect your mitochondria, the intersection of meditation and cellular health, and even the emerging role psychedelics might play in this space.Dr. Patel also shares his top tips for optimizing mitochondrial function and explains the science behind this cutting-edge testing method. If you're curious about performance, longevity, or just want to geek out on mitochondria with two scientists, this episode is for you. Let’s dig in.Sponsors:Tecton Life Ketone drink! https://tectonlife.com/ DRMIKE to save 20%LMNT electrolyte drink mix: miketnelsonlmnt.comDaily Fitness Insider Newsletter: https://flex-diet.kit.com/bfa1510fa8Flex 4: Dr. Patel's top 4 recommendations to improve mitochondriaTriphasic 2 book now available!Go to https://triphasic2.com/Episode Chapters:05:51 Dr. Patel's Journey into Mitochondrial Research08:34 Heat and Cold Stress in Mitochondrial Function12:18 Mitochondrial Function and Health19:50 Innovative Mitochondrial Testing31:05 Understanding Mitochondrial Respiration31:20 Testing Mitochondrial Efficiency31:51 Energy Production Pathways32:24 Free Radical Generation and Stress Testing32:58 Exercise Physiology and Mitochondria33:50 Personalized Mitochondrial Health Recommendations33:59 The Complexity of Mitochondrial Adaptation37:28 The Role of Membranes in Mitochondrial Health38:49 Oxygen's Dual Role in Life and Aging41:05 Preconditioning and Cardiovascular Health43:07 Hypoxic Training and Breath Work43:50 Meditation and Mitochondrial Function48:03 Psychedelics and Mitochondrial Changes54:33 Practical Tips for Mitochondrial Health56:12 Conclusion and Final ThoughtsFlex Diet Podcast Episodes You May Enjoy: Episode 164: How to use diagnostic testing to improve your metabolic health: An Interview with Sam MillerEpisode 190: Let’s Get Woo Woo – From Physics To Scientific Testing To Exercise Performance with Ian Mitchell of Wizard SciencesConnect with Dr. Patel: Instagram: https://www.instagram.com/hemalpatelphd/Website: https://mescreen.com/Enter code DRMIKE to save $100 - I don't make a dime off it. I would love to hear what you find, so hit me up if you try it!Get In Touch with Dr Mike:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpgEmail: https://miketnelson.com/contact-us/

Apr 16, 2025 • 1h 9min
Episode 319: Exploring the World of Peptides with Anthony Castore
Join me, Dr. Mike T. Nelson, on this episode of the Flex Diet Podcast as I sit down with peptide expert Anthony Castore for a deep dive into the world of peptides and performance. We cover everything from what peptides actually are to how they may support recovery, muscle growth, and immune function. We also explore the difference between standard peptides and bioregulators—plus how I’ve personally used compounds like BPC-157, Thymosin Beta-4, and ketone esters (including brands like Teton and KetoneAid) in my own routines.Anthony brings some fantastic insights on sourcing quality peptides, proper hydration protocols, and the latest in supplement strategies to enhance your health and performance.If you’re curious about the science behind these compounds and how to potentially integrate them into your training and recovery toolkit, you won’t want to miss this one.Sponsors:Tecton Life Ketone drink! https://tectonlife.com/ DRMIKE to save 20%LMNT electrolyte drink mix: miketnelsonlmnt.comDaily Fitness Insider Newsletter: https://flex-diet.kit.com/bfa1510fa8Triphasic 2 book now available!Go to https://triphasic2.com/Episode Chapters:05:40 Welcoming Anthony Castore to the Podcast05:50 Understanding Peptides and Their Applications08:52 Bio Regulators and Epigenetics15:23 Peptides for Joint Health and Aging22:03 Thymosin Alpha One and Immune Surveillance24:25 Ketone Esters and Their Benefits27:12 NAD Supplements and Alternatives31:10 Understanding the Benefits of ENOS Pathway and Nitric Oxide31:34 Comparing 5-Amino-1MQ and 1MNA for Athletes32:25 Resveratrol and Antioxidants: Benefits and Misconceptions34:02 The Role of Inflammation and Antioxidants in Exercise35:14 Exploring Astaxanthin and Its Benefits36:09 Ketone Supplements: Dosage and Effects44:51 Mercury Poisoning: A Personal Experience52:31 The Importance of Hydration and Peptide Efficacy01:03:15 Final Thoughts and Upcoming EventsFlex Diet Podcast Episodes You May Enjoy: Episode 144: Peptides – Bleeding Edge Performance, Muscle, and Recovery with Dr. Andy Galpin & Dr. Ryan GreeneEpisode 152: Testosterone, Muscle Mass, Cortisol, Collagen for Soft Tissue Repair an Interview with Dr Keith BaarConnect with Anthony: Castoremethod: https://www.castoremethod.com/Instagram: https://www.instagram.com/anthonycastoreGet In Touch with Dr Mike:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpgEmail: https://miketnelson.com/contact-us/

Apr 7, 2025 • 1h 10min
Episode 318: Could GAA Be the Next Creatine with Dr. Guillermo Escalante
Dr. Guillermo Escalante, an associate dean and creatine expert, joins to explore guanidinoacetic acid (GAA) as a potential game changer in supplements, comparable to creatine. They discuss its benefits for muscle and brain health, debating its efficacy and cost-effectiveness compared to creatine. The conversation shifts to the supplement industry's regulatory challenges and ethical implications within sports, particularly with the upcoming Enhanced Games, pushing for transparency in performance enhancement. This insightful dialogue is a must for anyone interested in the future of sports science.