JAMA Clinical Reviews

Barrett esophagus affects approximately 5% of people in the US and approximately 1% worldwide; it's associated with an increased risk of esophageal adenocarcinoma. JAMA Deputy Editor Mary M. McDermott, MD, interviews Prateek Sharma, MD, a gastroenterologist and professor of medicine at University of Kansas School of Medicine, about the diagnosis, surveillance, and available therapy for patients affected by Barrett esophagus. Related Article(s): Barrett Esophagus

Malaria is diagnosed in approximately 2000 people in the US each year. Delay in diagnosis or inappropriate treatment of malaria is associated with increased mortality. In this podcast, JAMA Deputy Editor Mary M. McDermott, MD, interviews Johanna P. Daily, MD, MS, Albert Einstein College of Medicine, an infectious disease expert and scientist studying malaria, on the diagnosis, treatment, and prevention of malaria in the US. Related Content: Diagnosis, Treatment, and Prevention of Malaria in the US

Pregnancy inherently increases the risk of death, but certain conditions during pregnancy are considered life-threatening. In this podcast, JAMA Associate Editor Linda Brubaker, MD, discusses with maternal-fetal medicine specialists William A. Grobman, MD, The Ohio State University, and Cynthia Gyamfi-Bannerman, MD, MS, University of California, San Diego, the categories of life-threatening conditions, as well as the racial and ethnic disparities associated with pregnancy-associated mortality. Related Content: The Leaked Supreme Court Ruling Opinion What Overturning Roe v Wade May Mean for Assisted Reproductive Technologies in the US

In July 2022, Kirsten Bibbins-Domingo, PhD, MD, MAS, took on a new role as the 17th editor in chief of JAMA and the JAMA Network. In conversation with Nobel laureate Harold Varmus, MD, Bibbins-Domingo discusses her research background, approaches to leadership in health care, and the critical role that journals play in communication about public health and science. Related Content: The Urgency of Now and the Responsibility to Do More—My Commitment for JAMA and the JAMA Network A Conversation With Dr Kirsten Bibbins-Domingo, JAMA’s New Editor in Chief (video) A Conversation With Dr Kirsten Bibbins-Domingo, JAMA’s New Editor in Chief (audio)

In the US, approximately 100 000 people have sickle cell disease, a chronic condition characterized by hemolytic anemia, acute and chronic pain, increased rates of stroke and nephropathy, and an average lifespan that is 20 years less than that of the general population. In this podcast, JAMA Deputy Editor Mary McDermott, MD, interviews review article author Patricia Kavanaugh, MD, on the diagnosis and management of sickle cell disease. Discussion includes a summary of 3 new therapies for sickle cell disease and some of the social, structural, and cultural challenges encountered by patients with sickle cell disease. Related Content: Sickle Cell Disease

Carpal tunnel syndrome and trigger finger are common hand conditions in primary care practice that are associated with pain and disability. In this JAMA podcast, JAMA Deputy Editor Mary M. McDermott, MD, and Kelly Currie, MD, assistant professor in the Washington University Division of Plastic & Reconstructive Surgery in St Louis, Missouri, discuss the diagnosis and treatment of these conditions and other hand problems that are commonly encountered in primary care. Related Content: Common Hand Conditions Patient Information: Carpal Tunnel Syndrome

JAMA Associate Editor Ethan Basch, MD, and Melanie Calvert, PhD, from the University of Birmingham, UK, discuss barriers to and strategies for including rigorous patient-reported outcomes in clinical trials, and reflect on Dr Calvert’s recent JAMA paper on related ethical implications. Related Content: Ethical Considerations for the Inclusion of Patient-Reported Outcomes in Clinical Research

JAMA Associate Editor Linda Brubaker, MD, MS, from University of California San Diego, discusses the implications of self-monitoring of blood pressure in higher-risk pregnancies with Richard J. McManus, MBBS, PhD, from University of Oxford, UK, and Lucy C. Chappell, MB BChir, PhD, from King's College London. Related Content: Effect of Self-monitoring of Blood Pressure on Diagnosis of Hypertension During Higher-Risk Pregnancy Effect of Self-monitoring of BP on BP Control in Pregnant Individuals With Chronic or Gestational Hypertension Management of Chronic Hypertension During Pregnancy Self-monitoring of Blood Pressure During Pregnancy

Lumbar spinal stenosis is a common cause of low back pain and disability in older people. Both nonoperative and operative therapies can improve symptoms from spinal stenosis. In this podcast, Jeffrey Katz, MD, MSc, from Harvard Medical School joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss current evidence regarding diagnosis and optimal treatment of lumbar spinal stenosis, including when to consider invasive therapies for patients with symptoms of lumbar spinal stenosis. Related Content: Diagnosis and Management of Lumbar Spinal Stenosis

After certain adverse pregnancy outcomes, an individual’s risk for cardiovascular and other diseases increases. JAMA Associate Editor Linda Brubaker, MD, discusses these complications as indicators of future health problems, who is at risk, and what can be done to improve health for at-risk individuals and populations with Lynn M. Yee, MD, MPH, and JAMA Senior Editor Philip Greenland, MD, from Northwestern University, and Eliza C. Miller, MD, MS, from Columbia University. Related Content: Mitigating the Long-term Health Risks of Adverse Pregnancy Outcomes To Prevent Cardiovascular Disease, Pay Attention to Pregnancy Complications