With a replacement of the controversial Liverpool Care Pathway expected over the next few months Professor Keri Thomas, National Clinical Lead at the GSF Centre for End of Life Care, debates the need for change and calls for a more personalised care for the dying. And Inside Health examines differences in sex development, when it is unclear if a new born baby is a boy or a girl. Plus, does the environment of your GP's surgery increase or alleviate anxiety?

Dr Mark Porter finds out why insomnia can often go untreated by the NHS despite there being a treatment that not only works but also doesn't involve drugs. There are nearly 11 million prescriptions for sleeping tablets in the UK every year but their effect isn't long lasting and people can find it hard to come off the tablets. Cognitive behavioural therapy has consistently been shown to be very effective at improving sleep in the long term but few people have access to it. Mark is joined by Colin Espie, professor of Sleep Medicine at the University of Oxford, and by professor Kevin Morgan, director of the Clinical Sleep Research Unit at Loughborough University, to discuss why insomnia is so neglected, and to talk about the success of methods to deliver CBT online using mobile and web technology.Also in the programme, Mark talks to Peter Goadsby, professor of neurology at King's College Hospital London, to find out what cluster headaches are, why they're so painful and why they can occur when the clocks change. He also meets Ann McNeil, professor of tobacco addiction at the Institute of Psychiatry, to bust the myth that smoking helps bust stress.

A committee advising the Food and Drug Administration in the US has voted to change the way it tests women for cervical cancer by solely using a test that detects Human Papilloma Virus (HPV) rather than also using a standard smear test which looks for abnormal cell changes. The test is likely to become more widely used in the NHS than it is now. What advantages does it offer over smear tests and what difference will it make for women? Dr Mark Porter talks to Jack Cuzick, director of the Wolfson Institute of Preventive Medicine and GP Dr Margaret McCartney about the pros and cons.The HPV virus is responsible for a big increase in the number of oral cancers. Some researchers have even gone so far as to call it an epidemic. Mark talks to head and neck cancer surgeon Andrew Schache from the University of Liverpool to find out more about the reason for the rise in numbers.Also in the programme. You are when you eat. According to some diets, not eating in the evening can help you lose weight. But does the timing of when you eat really make a difference? Susan Jebb, professor of diet and population health at the University of Oxford, explains why the time you eat doesn't make a difference to whether you put on weight.Scar free surgery. Mark talks to Mikael Sodergren from Imperial College London, about the latest surgical innovation - natural orifice surgery. Surgery via natural orifices like the stomach and vagina can dramatically improve people's recovery after an operation reducing their pain and time in hospital. Currently only used in women, in the future it could be available for everyone with a robotic surgical device going in through the mouth and then being used to perform operations like an appendectomy via the stomach.

Is sugar really addictive? As the Chief Medical Officer for England suggests that it is and a 'sugar tax' may have to be introduced, leading experts debate whether the white stuff on our table is really habit forming.How 40 year old research hidden away in a book has thrown new light on a link between iron deficiency and stroke.And why the clue to solving recurrent thrush maybe getting the diagnosis right in the first place.Plus concern about the increase in prescription charges just announced by the government.

Dr Mark Porter investigates a pioneering research project designed to reduce the psychological trauma experienced by more than half of critically ill patients after a stay in intensive care. Why do treatments on ICU cause hallucinations and post traumatic stress disorder in patients months after they leave hospital? Mark talks to the doctor who believes people over the age of eighty are being overtreated to protect them against heart attack and stroke. He finds out why some of the drugs used could increase their risk of falls. Also in the programme, how lens replacement surgery for cataracts is also being used to correct vision. And why are cases of scarlet fever on the rise?

Selenium supplements have hit the headlines with reports that men taking them can increase their risk of developing aggressive prostate cancer. Dr Mark Porter talks to leading expert on selenium, Margaret Rayman, Professor of Nutritional Medicine at the University of Surrey, to find the truth behind the story.Idiopathic pulmonary fibrosis is a disease that kills more people in the UK than breast cancer. It's caused by the thickening and scarring of the part of the lung that forms the barrier between blood and air and can make your chest sound like it's full of Velcro. Mark talks to Luca Richeldi, Professor of Respiratory Medicine at the University of Southampton, about why it can be mistaken for asthma or Chronic Obstructive Pulmonary Disease - what used to be called emphysema and bronchitis. Also in the programme, as many as 1 in 20 children will experience long term constipation with no underlying cause and which doesn't get better with dietary changes. Mark visits a specialist clinic at Addenbrooke's hospital in Cambridge to meet families managing the problem.

Dr Mark Porter investigates the health effects of loneliness and why some researchers believe being lonely is worse for your health than obesity. Also in the programme, as proposed new UK guidelines mean as many as 5 million more people could be prescribed statins to lower their cholesterol how do you work out if you are in this new category of being at risk? Are the current calculators that work out your risk up to the job? Mark also investigates coughs. Does it really make a difference if your cough is viral or bacterial, and why eighty percent of people won't benefit from taking antibiotics for their cough. A recent study has found that long term, repeated exposure to air pollution increases the risk of heart attacks. What does this mean for people who live near busy roads, and who is most at risk? Mark Porter talks to Frank Kelly, professor of environmental health at King's College London about why the microscopic particles in air pollution cause problems for the heart and why he believes cycle routes shouldn't be on busy, main roads.

As NICE issues its latest guidelines for treating osteoarthritis, Inside Health looks at the use of paracetamol to relieve pain and is glucosamine a recommended supplement? Also in the programme, Dr Mark Porter investigates how the latest drug treatments for problem drinking work. And how much do doctors use their gut instinct when it comes to diagnosing patients?

Why testosterone prescriptions are on the increase in the UK and growing concern amongst some doctors that these supplements may be linked to heart attack.Do the hours spent on laptops or tablets before bedtime disrupt your sleep?Dr Margaret McCartney reviews the evidence for later school start times for teenagers to match their natural bodyclocks. And a listener's concern about antidepressants in pregancy - 1 in 30 women take medication for depression whilst expecting a baby, but does the science suggest these drugs are harmful?

As the government calls for a ban on the sale of e cigarettes to under 18s, Dr Mark Porter is joined by Martin McKee, Gerard Hastings and Robert West to discuss who is using them and how they are being advertised. The chairman of NICE, David Haslam has suggested patients should demand more NICE approved drugs from their GP. Mark is joined by David and by GP Margaret McCartney to discuss whether patients really should be more pushy. Also in the programme Mark talks to Mark Emberton at University College London Hospital in London about the PROMIS trial into the benefits of using MRI to scan men's prostate gland to detect cancer.