
This Week in Startups
Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.
Latest episodes

47 snips
Nov 23, 2024 • 59min
How Startups Can Crush Enterprise AI Sales | E2050
Joff Redfern, a Venture Partner at Menlo Ventures and former Chief Product Officer at Atlassian, and Derek Xiao, also a Venture Partner at Menlo Ventures and former President of the Harvard Crimson, share insights on AI's transformative role in enterprises. They discuss the surging spending trends in AI, particularly in healthcare and legal sectors. The duo explores generative AI applications, revealing innovative use cases like enterprise search and support chatbots. They also emphasize strategies for AI startups amidst an evolving landscape toward artificial general intelligence.

12 snips
Nov 22, 2024 • 1h 18min
TWiST News: Nvidia's AI Edge, Google Might Have to Sell Chrome, and Founder Fridays Updates | E2049
Jean-Paul Schmetz, Head of Brave Search and Ads, discusses the competitive search landscape and Google's antitrust issues, including the possibility of Google having to sell Chrome. Georges Colbert, CEO of Albatroz.ai, shares insights from hosting Founder Fridays, emphasizing the importance of community and collaboration among startup founders. They explore the impact of Nvidia's advancements in AI chips and the implications of regulatory actions on Google's market dominance, sparking a riveting conversation on innovation and competition.

5 snips
Nov 21, 2024 • 1h 15min
TWiST News: Venture-Backed Defense Startups, Anti-Drone Guns, and Querio's AI Data Platform | E2048
This time, Steven Simoni, CEO of Allen Control Systems, shares insights on building autonomous gun systems for defense, touching on innovations in anti-drone technology and their implications for military applications. Rami Abi Habib, CEO of Querio, discusses democratizing data analysis with their user-friendly business intelligence platform, aimed at making complex data processes accessible to everyone. Together, they explore the intersections of technology and defense while highlighting the evolving landscape of data management.

18 snips
Nov 19, 2024 • 1h 4min
Anatomy of a Win-Win Acquisition: Synergy, Growth, AI, and the Future of SaaS | E2047
Spencer Skates, CEO of Amplitude, and James Evans, CEO of Command AI, explore the strategic acquisition of Command AI by Amplitude. They discuss the integration of Command AI’s user assistance technology to enhance user feedback and engagement. The conversation covers startup M&A trends, the challenges of aligning company cultures during acquisitions, and the importance of product-led growth. Spencer also shares candid thoughts on private equity's impact on the market and the future of AI in user experiences.

Nov 19, 2024 • 1h 20min
TWiST News: Netflix Goes Live, The FCC Revamp, Free Speech, and Regulatory Shifts | E2046
The hosts dive into Netflix's challenges with live sports streaming, discussing a notable boxing disappointment during a high-profile fight night. They explore the shifting dynamics in sports broadcasting, including implications for betting and subscription versus ad-based revenue models. The conversation shifts to the new FCC chair's controversial stance on social media regulation and free speech. Finally, they contemplate the potential impact of Emile Michael leading the Department of Transportation, emphasizing the need for business-savvy leadership in government.

17 snips
Nov 15, 2024 • 1h 2min
Misaligned Incentives Between GPs and Founders with Altimeter's Jamin Ball | E2045
Jamin Ball, an investor at Altimeter and former banker, shares his insights on the complex dynamics between VCs and founders. He discusses how overcapitalization can lead to unrealistic growth expectations and misaligned incentives. The conversation touches on the rapid surge in venture capital, the stark contrasts between private and public valuations, and the effect of AI on the startup landscape. Jamin also examines the challenges of IPOs, the importance of choosing effective funding partners, and the current SaaS market conditions.

13 snips
Nov 15, 2024 • 1h 33min
TWiST News: Face Robots, Solar's Growth, The Polymarket Mess, and YC's Latest Call for Startups | E2044
Phil Deutch, CEO of NGP Energy Tech Partners, shares insights on solar power's explosive growth and its role in meeting energy demands from data centers. He discusses Australia's achievements in renewable energy and the potential for similar success globally. The conversation highlights the shifting perceptions of nuclear power, particularly small modular reactors, and their importance for a sustainable future. Lastly, the discussion touches on the FBI's raid on Polymarket's CEO and its implications for prediction markets and startups.

Nov 14, 2024 • 1h 15min
TWiST News: Underwater Drones, Robot Swarms, and Klarna's Going Public | E2043
Nelson Mills, co-founder of VATN Systems, discusses breakthroughs in underwater drone technology designed for both defense and commercial applications. He elaborates on the agility and cost-efficiency of these drones compared to traditional military technologies. The conversation shifts to geopolitical challenges, particularly concerning China's maritime ambitions and the U.S. response. Mills explains the complexities of underwater drone communication and the innovative solutions being developed to enhance their operational capabilities.

14 snips
Nov 11, 2024 • 1h 23min
TWiST News: Serve Robotics, High Skill Immigration, and the Trump Trade | E2042
Ali Kashani, CEO and co-founder of Serve Robotics, discusses the future of autonomous delivery with Jason and Alex. They delve into the innovative technology behind delivery robots and their partnership with Uber Eats. The conversation shifts to the implications of high-skill immigration policies and their effects on the workforce. They also analyze the stock market's current state, questioning if it is overvalued. The trio shares insights on balancing technology advancements with regulatory challenges in the rapidly evolving delivery industry.

4 snips
Nov 8, 2024 • 1h 30min
TWiST News: Reddit Earnings, Apple Intelligence, and more AI money | E2041
The hosts dive into Apple’s innovative on-device AI and its potential privacy pitfalls. They analyze Reddit’s impressive surge in user engagement and discuss Amazon's major investment interest in AI firm Anthropic. Conversations expand to touch on the critical importance of product velocity for SaaS growth, illustrated through Toast’s success story. The political landscape is also examined, focusing on how economic factors and inflation could sway voter sentiment in upcoming elections.
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