

This Week in Startups
Jason Calacanis
Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.
Episodes
Mentioned books

16 snips
Sep 5, 2023 • 43min
Next Unicorns: Preventing future fraud using AI with Sardine CEO Soups Ranjan | E1802
Soups Ranjan, CEO and Co-founder of Sardine and former Coinbase risk management director, shares insights on the evolving landscape of online fraud. He discusses alarming tactics like 'pig butchering' scams and examines how generative AI poses new challenges for security. Soups highlights Sardine's innovative machine learning solutions for fraud prevention. The conversation also delves into the differences between intrinsic and extrinsic AI and emphasizes the necessity of enhancing security across various sectors to combat persistent fraud threats.

Sep 4, 2023 • 55min
Building a blood-testing startup in 2023 with Vital CEO Vasu Nadella | E1801
Vasu Nadella, CEO and co-founder of Vital Biosciences, shares his insights on revolutionizing blood testing with the VitalOne device, capable of conducting over 50 tests from a tiny blood sample. He discusses trust-building with investors after industry failures, the mission to enhance healthcare accessibility, and innovative tech's role in diagnostics. Vasu also explores the integration of AI and robotics in lab settings, emphasizing a shift toward proactive health management and the importance of transparency in patient care.

33 snips
Sep 1, 2023 • 1h 7min
Bootstrapping to IPO, product-led growth, & scaling SaaS with Atlassian's Scott Farquhar | E1800
Scott Farquhar, Co-CEO and co-founder of Atlassian, shares insights from bootstrapping his company to an IPO. He discusses the challenges faced during the dot-com crash and the innovative strategies that paved their way. Farquhar also reflects on the lessons from HipChat's acquisition and how product-led growth can propel SaaS success. The conversation dives into the impact of generative AI on enterprise software and the balance between organic growth and sales efforts in tech.

4 snips
Aug 30, 2023 • 1h 5min
Next Unicorns: Developing drugs to extend dog lifespans with Loyal CEO Celine Halioua | E1799
Celine Halioua, CEO and founder of Loyal, explores groundbreaking ways to extend dog lifespans through innovative drug developments. With her background in neuroscience, she discusses the benefits of canine-specific medications and the parallels between dog and human aging. The episode delves into the challenges of developing effective treatments while addressing genetic issues stemming from selective breeding. Celine also shares insights on the ethics of veterinary research and the critical role of continued advancements in pet health for overall well-being.

5 snips
Aug 29, 2023 • 1h
NEWS: Instacart and Klaviyo file for IPO, State of VC distributions, AI lawsuits | E1798
The podcast dives into the IPO filings of Instacart and Klaviyo, marking a significant return for venture capital since 2021. It discusses the shifts in the VC exit market and the mounting pressures on performance metrics. Listeners learn about the legal battles involving AI companies, and the impact of advertising dollars on new platforms. The show also explores Instacart’s financial rollercoaster and Klaviyo’s effective marketing strategies, as well as new trends in consumer models and innovations in real estate investment.

5 snips
Aug 24, 2023 • 1h 26min
NEWS: Nvidia’s insane earnings beat, Arm’s IPO filing, and more! | E1797
Dive into Nvidia's explosive quarterly earnings and how they’ve reshaped the tech landscape. Discover Arm's significant IPO filing and its implications for the industry. There's valuable insight on navigating accelerators for founders, and the discussion also highlights GPU investment trends and startup product velocity. The conversation wraps up with the intricacies of Arm's business model amidst competition and the evolving dynamics of the tech world. Don't miss the ethical critiques surrounding startup funding and accelerator practices!

21 snips
Aug 23, 2023 • 49min
Next Unicorns: Empowering robots to think for themselves via AI with Covariant’s Peter Chen | E1796
Peter Chen, CEO and co-founder of Covariant and former OpenAI researcher, dives into the revolutionary potential of AI in robotics. He discusses how reinforcement learning is key to enabling robots to learn and adapt in dynamic environments, far beyond simple tasks. Chen also explores the balance between robotic arm functionality and adaptability, tackles the challenges of data collection for AI training, and shares insights on the promising future of humanoid robots in various industries.

17 snips
Aug 22, 2023 • 59min
Is Nvidia overpriced? Plus, price targets, GodMode demo, and more! | E1795
Sandeep Madra, an AI expert and contributor to Definitive Intelligence, joins Jason to discuss the implications of Nvidia's valuation amid rising tech demand. They dive into advancements in AI technology, showcasing an impressive AI dubbing tool and a groundbreaking demonstration that recreates songs from brain signals. The conversation touches on Nvidia's competitive edge in the AI landscape and addresses the evolving challenges in AI content creation, making it a fascinating exploration for tech enthusiasts.

83 snips
Aug 18, 2023 • 1h 15min
Inflection AI CEO Mustafa Suleyman on building modern AI, DeepMind origins, and much more | E1794
Mustafa Suleyman, CEO of Inflection AI and co-founder of DeepMind, shares fascinating insights about the early days of DeepMind and its pivotal role in AI's evolution. He discusses the crucial advancements in computing hardware and how they are shaping AI's future. Suleyman also highlights the balance required between speed, cost, and quality in AI model performance. Additionally, he touches on the ethical considerations of AI deployment and reflects on his new book, 'The Coming Wave,' offering a glimpse into the future of technology and its societal impacts.

11 snips
Aug 16, 2023 • 1h 31min
Next Unicorns: Manufacturing pharma drugs in space with Varda’s Delian Asparouhov | E1793
Delian Asparouhov, co-founder and president of Varda, dives into the thrilling concept of manufacturing pharmaceuticals in space, emphasizing its potential and the technological advancements driving this frontier. He discusses the shifting culture in Silicon Valley towards defense collaborations and venture capital dynamics. Maret Thatcher, CEO of Argyle, shares insights on leveraging augmented reality to revolutionize construction project management, highlighting its impact on efficiency and team communication. The conversation is a fascinating blend of innovation, challenges, and the future of tech in manufacturing.