CRAFTED.

In this insightful discussion, Amy Kruse, a neuroscientist and Chief Investment Officer at Satori Neuro, and Matias Serebrinsky, co-founder of PsyMed Ventures, delve into the transformative role of AI and biotechnology in mental health. They explore the hype around psychedelics and emphasize the significance of the gut-brain axis. The duo also highlights the evolution of neurotechnology and the potential for innovative treatments, alongside the challenges of funding health tech startups, particularly focusing on mental wellness and women's health.

Pablos Holman, an inventive force in deep tech, has collaborated with giants like Jeff Bezos and Bill Gates. He argues that while software has dominated, real-world issues like energy and sanitation require robust hardware solutions. This discussion unveils visionary ideas such as space-based solar panels beaming energy to Earth, eco-friendly autonomous cargo ships, and underground nuclear reactors to meet energy demands. Pablos urges tech professionals to pivot from software to hardware to drive the innovations essential for a sustainable future.

Sam Gregory, Executive Director of WITNESS, is an expert on deepfakes and AI's impact on trust. He discusses the alarming ease of creating deepfakes and their potential to mislead the public. The podcast reveals how audio deepfakes pose unique threats and examines their limited impact on the 2024 US Presidential Election. Gregory emphasizes the mantra 'Prepare, Don’t Panic' for addressing AI challenges and offers practical steps for software makers to enhance transparency and ethical use, all while empowering human rights defenders.

Accounting may not be the sexiest part of running a business, but according to Sasha Orloff, it’s the key to understanding your company’s financial health—and ultimately, its success. At his previous two startups, Sasha was frustrated that he didn’t have a real-time view into his company’s financial health. And he realized the problem wasn’t accounting – but accounting software. So, Sasha founded Puzzle, because “it's hard to set yourself up for success if you don't know when you're about to run out of money.” Sasha is on a mission to make accounting intuitive, real-time, and accessible for founders and finance teams alike. In this episode of CRAFTED., we explore how Sasha is crafting Puzzle, how AI makes this the right moment to challenge QuickBooks, and why he was so confident that the market needed Puzzle that he was undaunted by the five years he estimated it would take to build an MVP. "We’re not just rethinking accounting software—we’re rethinking how founders and CEOs can make data-driven decisions to build enduring companies." Sasha shares:How the frustration he felt at his previous startups led him to Puzzle Why “accounting gets a bad rap”, but it crucial for founders: it’s your financial healthWhy second-time founders are ideal customersWhy it took five years to build an MVP – and why he wasn’t daunted by this expectationWhy the problem was never accounting, but accounting software and the distorted realities it’s built to createWhy AI and modern API’s made now the right time to build PuzzleWhy Puzzle is “poking the bear” and putting highway billboards up near QuickBooks HQ(01:04) - Sasha’s finance frustrations at previous startups (02:15) - Traditional accounting software isn’t made for founders (02:15) - The problem with traditional accounting software (05:01) - What Puzzle does differently: Real-time financial health (07:52) - AI’s role in revolutionizing accounting (10:22) - Why second-time founders are Puzzle’s ideal users (12:48) - Building a five-year MVP: Challenges and conviction (16:41) - Tackling QuickBooks: Bold marketing moves and billboards (19:15) - Understanding edge cases and complexity in accounting (23:07) - The future of Puzzle: Helping startups thrive (27:01) - Hosting the Turpentine Finance podcast Links:Learn more about Puzzle: Puzzle.ioFollow Sasha Orloff on LinkedIn: Sasha OrloffTurpentine Finance Podcast: Turpentine FinanceCRAFTED. is produced by Modern Product Minds, where CRAFTED. host Dan Blumberg and team can help you take a new product from zero to one... and beyond. We specialize in early stage product discovery, growth, and experimentation. Learn more at modernproductminds.com Subscribe to CRAFTED., follow the show, and sign up for the newsletter 👉 crafted.fm

AI democratizes things. It's enabling designers to be developers, and developers to be designers… And in this episode, Aaron Walter and Eli Woolery explain how AI “changes the game” for designers. As co-founders of Design Better, Aaron and Eli advise companies on how to incorporate AI into their design process. We’ll explore how AI can help designers explore a problem more thoroughly, as well as some pitfalls to watch out for. (Hint: speed is not always a good thing.)Aaron and Eli are also hosts of the popular Design Better podcast, where they’ve interviewed some of the world’s most creative people. Featuring software designers, as well as famous musicians, artists, architects, and more, the duo explore the creative process. And there are some striking similarities across disciplines.For more on Aaron and Eli and to subscribe to the Design Better podcast and newsletter, see DesignBetterPodcast.com ***CRAFTED. is produced by Modern Product Minds, where CRAFTED. host Dan Blumberg can help you take a new product from zero to one... and beyond. We specialize in early stage product discovery, growth, and experimentation. Learn more at modernproductminds.com Subscribe to CRAFTED., follow the show, and sign up for the newsletter 👉 crafted.fm

Amir Nathoo is reimagining the future of education by building products that put students at the center of their learning experience. As the Founder and CEO of Outschool, Amir has created a marketplace for remote, personalized, interest-based learning that’s challenging traditional K-12. In this episode of CRAFTED., we explore how Amir founded and grew Outschool, including the 15x spike in usage during the pandemic. Post-pandemic, alternative education and homeschooling continues to rise. As Amir says: “The idea that a single institution could fulfill all of your kids' needs or all of all kids' needs is completely unrealistic…. Mass personalization is needed.” And he sees Outschool as the integration layer for all those teachers, students, and institutions. You will learn a ton from Amir’s approach to product development and disruption. Key takeaways for product builders: 1. Start with a Niche Audience, Then ExpandAmir and Outschool began by targeting a specific group—secular homeschoolers—who had unmet needs in education. By serving this niche well, they achieved product-market fit before scaling to a broader audience. 2. Co-Creation, FTWOutschool's initial product was shaped through customer co-creation and iterative development, testing small features before scaling them. 3. Solve Real Problems, But Keep Early Stakes LowWhile Outschool addressed a critical need (supplemental education), they started with interest-based, "low-stakes" classes. This allowed them to test and refine their offering without the pressure that would’ve come with offering “core” classes. 4. Build a Two-Sided Marketplace with BalanceCreating a thriving marketplace like Outschool required balancing teacher supply with student demand. Amir emphasized solving the “chicken and egg” problem by manually curating both sides early on. 5. Pay Attention to the Market and Adapt QuicklyWhen the COVID-19 pandemic hit, Outschool responded quickly by offering free training sessions for schools who needed to understand remote learning, scaling their platform, and adding free classes to serve families in need. ***Never miss an episode! Subscribe to CRAFTED. in your favorite podcast app and sign up for the newsletter at crafted.fmCRAFTED. is produced by Modern Product Minds, where CRAFTED. host Dan Blumberg and team can help you take a new product from zero to one... and beyond. We specialize in early stage product discovery, growth, and experimentation. Learn more at modernproductminds.com 

Hilary Mason is a world-builder. She’s a serial entrepreneur, machine learning expert, and now, as the founder and CEO of Hidden Door, she’s creating immersive experiences where fans can interact with their favorite characters from books and movies. The choose-your-own-adventures style games are an amazing blend of AI and human creativity — and Hilary is passionate about both: “If I write a manifesto, this is what it'll be: I don't think the power of generative AI is to create the next amazing novel. I don't think it's gonna create the next amazing movie. I think it is not opinionated, but people are opinionated and people will create those things using these tools.”On this episode of CRAFTED., we discuss what AI is good at and how to create a great marriage of human and machine. And Hilary is not holding back… “Doing data work without a soul or without philosophy is, at best, meaningless and, at worst, harmful.”“I think prompts are gonna go away. We're in a moment of industry-wide product design, chaos…”Listen for a masterclass on building with AI and building with creativity and soul.(02:00) - – This moment in AI: figuring out the right use cases and design patterns (05:00) - – Founding Hidden Door (09:00) - – Why “controllability” is so important (11:00) - – Enabling fans want to play with their favorite characters (13:00) - – Why text-based games are so great (15:00) - – Behind the scenes of how Hidden Door builds for fun (19:00) - – AI has caused a moment of “industry-wide product design chaos” (23:00) - – Industries and use cases where AI will be really good; where it won’t (25:00) - – Effective ways to get beyond AI mediocrity (28:00) - – Why Hilary thinks prompts will soon go away (31:00) - – Hilary’s liberal arts background: English + Computer Science (33:00) - – Why we need philosophy and soul along with the data Where to find Hidden Door:https://www.hiddendoor.co/Where to find Hilary Mason:LinkedIn: https://www.linkedin.com/in/hilarymason/X: https://x.com/hmason Where to find Dan Blumberg:Website & newsletter: https://www.crafted.fm LinkedIn: https://www.linkedin.com/in/dblums/X: https://x.com/dblumsCRAFTED. is produced by Modern Product Minds, where CRAFTED. host Dan Blumberg and team can help you take a new product from zero to one... and beyond. We specialize in early stage product discovery, growth, and experimentation. Learn more at modernproductminds.com 

As AI models grow larger and more powerful, they promise incredible capabilities — but at what cost? Karen Hao is a journalist and former engineer who writes about the impact of artificial intelligence on society for The Atlantic and other top publications. On this episode of CRAFTED., we discuss whether the largest AI models are worth their hefty footprint: They consume massive amounts of electricity and water and Karen argues that smaller models better balance cost vs. benefit. Karen will also provide a view of AI from outside — far outside — Silicon Valley. She’s reported on AI from across the Global South and we’ll hear about the fight over data centers in Chile, how New Zealand’s Maori people are using AI to preserve their indigenous language, and why it’s a problem that AI can speak any language, but can only really be policed in a few.Key Moments:(01:51) - - The view of AI from the Global South (04:08) - - Data centers are thirsty and their benefit is unclear to locals in Chile (and elsewhere) (09:16) - - GenAI is English-first: Why it’s not as safe in other languages (12:12) - - Why some activists call AI a new form of “colonialism” (14:50) - - Indigenous communities innovating with AI (17:46) - - The case for smaller AI models (19:40) - - Why open source AI is so important (25:09) - - AI and the environmental impact: Karen’s reporting on Microsoft’s “hypocrisy” (28:40) - - Are big AI models worth the cost? (34:56) - - How Karen trains journalists to cover AI Where to find Karen:Website: https://karendhao.com/X: https://x.com/_KarenHaoLinkedIn: https://www.linkedin.com/in/karendhao/Threads: https://www.threads.net/@_karenhaoArticles Mentioned:Microsoft’s Hypocrisy on AI (The Atlantic) A new vision of artificial intelligence for the people (MIT Technology Review)AI Is Taking Water From the Desert (The Atlantic)Where to find Dan Blumberg:Website & newsletter: https://www.crafted.fm LinkedIn: https://www.linkedin.com/in/dblums/X: https://x.com/dblumsCRAFTED. is produced by Modern Product Minds, where CRAFTED. host Dan Blumberg and team can help you take a new product from zero to one... and beyond. We specialize in early stage product discovery, growth, and experimentation. Learn more at modernproductminds.com Subscribe to CRAFTED., follow the show, and sign up for the newsletter 👉 crafted.fm

Russ Somers has tripled his productivity by building a “GPTeam” of AI “employees.” In this episode, from Beyond the Prompt, the head of marketing for Quantified reveals how he’s done it, and how you can build your own virtual team to be more productive and creative. Russ’s virtual team helps with tasks ranging from webinar content creation to specialized knowledge acquisition. Through personal anecdotes and exploratory conversations, the episode delves into the process of building AI team members, the importance of play in learning and innovation, and strategies for incorporating AI into personal and professional growth. Highlights include building AI with specific skill sets like 'Wendy Webinar' and 'Roger RevOps,' and the philosophical implications of personifying AI for better engagement and output. And Russ's personal journey from a layoff to pioneering AI productivity tools opens a discussion on the transformative power of AI in the modern workplace.Subscribe to Beyond the Prompt on Spotify, Apple, or your favorite podcast app. And follow hosts Henrik Werdelin and Jeremy Utley on LinkedIn. Key Moments:(00:48) - Meet Russ Summers: The One-Man Marketing Powerhouse (02:30) - Introducing Wendy Webinar: A GPT Team Member Revolutionizing Content Creation (04:30) - Leveling Up with GPT: Beyond Basic Task Automation (06:00) - Roger RevOps: A Custom GPT for Niche Expertise (08:55) - Exploring the Next Frontier: Collaborative and Mentorship GPTs (15:13) - The Art of Building and Utilizing GPT Staff: Tips and Tricks (23:15) - Expanding the Team: Integrating GPTs into Human Workflows (24:30) - Exploring Organizational Progress and Tool Adoption (26:13) - The Importance of Measuring Effort and Encouraging Experimentation (27:38) - Fostering Creativity and Psychological Safety in the Workplace (29:54) - Personifying Bots for Better Engagement and Output (32:30) - Reimagining Brand Communication in a Conversational World (35:46) - The Transformative Power of Play and Exploration (39:31) - Strategies for Personal and Professional Growth with GPT (48:42) - Concluding Thoughts on Innovation and the Future of Work

Kira Radinsky is the CEO of Diagnostic Robotics, which uses AI to make predictions that help patients get better healthcare. She’s also the co-founder of Mana.bio which is using AI to automate drug discovery. On this episode of CRAFTED., Kira will share more on why she believes that, of all the industries that AI will change, it’s those involving chemistry and biology that will change the most. Plus, why she says: “I just want AI to replace me as a scientist.” Kira shares:How Mana.bio is using AI to build new “rocketships” that can deliver drugs to the right planets (cells) — and how they’ve done things in three months that used to take 20 yearsHow AI is accelerating drug discovery by creating feedback loops that speed up learningHow Diagnostic Robotics makes predictions on patient outcomes that help doctors and care teams provide better careWhy she loves making predictions — Kira is famous for them. Over a decade ago, while getting her PhD and working with Microsoft, she built systems that successfully predicted cholera outbreaks and riots.How to incentivize bots to make bolder predictions. i.e. It’s easy to predict that there will not be an earthquake today; it’s harder to say today there will be one. Why predictions are only valuable if there’s something you can do to prevent bad outcomes — and why this makes healthcare an ideal fieldHow advances in software have enabled her to follow her dream and be a scientist. (Kira doesn’t have the great hands you need to be a lab chemist.)Key Moments (02:29) - Why predictions have been so important to Kira from an early age, and her dream to be a scientist (05:46) - How Kira predicts the future and how she became famous for predicting the first cholera outbreak to hit Cuba in more than 100 years (09:49) - How Diagnostic Robotics makes predictions that improve healthcare outcomes (14:22) - Big unlocks to make better predictions — and explain them to doctors (16:42) - What’s “easy” to predict and what’s hard; how to incentivize bots to make bold predictions (e.g. an earthquake) (18:49) - Founding Mana.bio and how AI can improve drug discovery (23:37) - AI will have a huge impact on the administrative aspects of patient care (28:07) - How Mana.bio creates rapid learning feedback loops (29:54) - Tips for building with GenAI and why more attention should be paid to causal inference (32:52) - Where GenAI will be really transformative in the future (34:35) - Outro CRAFTED. is brought to you in partnership with Docker, which helps developers build, share, run and verify applications anywhere – without environment confirmation or management. More than 20 million developers worldwide use Docker's suite of development tools, services and automations to accelerate the delivery of secure applications. CRAFTED. is produced by Modern Product Minds, where CRAFTED. host Dan Blumberg and team can help you take a new product from zero to one... and beyond. We specialize in early stage product discovery, growth, and experimentation. Learn more at modernproductminds.com Subscribe to CRAFTED., follow the show, and sign up for the newsletter 👉 crafted.fm