What I Know

By the time he teamed up with Harvard geneticist George Church to found Colossal Biosciences, Ben Lamm had founded, built, and sold five companies. This one would be the most audacious yet: Its goal is to create disruptive conservation technologies, including, to de-extinct the woolly mammoth. Yes, it is actively working to edit elephant genes to create a cold-hearty herbivore to help decelerate melting of the arctic permafrost, and, thus, prevent release of 600 tons of carbon a year. It’s also working with existing species-conservation efforts globally–and hopes to apply its technology to save animal populations from going extinct. But with the audacious mission comes a lot of questions–and many critics. Lamm told host Christine Lagorio-Chafkin that he learns more from his detractors than from his supporters–and he welcomes both hearing from them, and, in a couple cases, he’s actually hired them to work with him.

The co-founder and chief executive of Full Circle Brands manages three sustainability-minded international brands out of New York City. He tells host Christine Lagorio-Chafkin how he boost productivity by keeping his meetings short, and cramming them all into one day. Plus: When his team is in the office, he plays jazz–and orders comfort food. 

He and his co-founder dreamed up their company over an unconventional Thanksgiving dinner in Shanghai. In 2009, they launched Full Circle, a line of sustainable household goods–and set out to change consumer perception about “eco” products. Today, they run three brands, including Full Circle, For Good, a line of household disposables, like compostable bags, and Soma, a line of filtration, pitchers, and bottles. He spoke with host Christine Lagorio-Chafkin about building a sustainable supply chain, bootstrapping his business from the start, and why his companies’ giving-back pledges of profits are so meaningful to their teams.

If there was a super-simple way to tweak the whole way you think about an experience…would you do it? Serial entrepreneur Toni Ko, the woman behind NYX Cosmetics, Perverse Sunglasses, and, most recently, Bespoke Beauty Brands, explains to host Christine Lagorio-Chafkin how she changes her wording to change her perspective.

Her family emigrated from Korea when she was 13 years old, and serial entrepreneur Toni Ko has since founded three different–each totally fascinating–companies. Her first, NYX Cosmetics, made $4 million in its first year, and, within a decade, was in beauty aisles of Target nationwide. But with growth, came some sacrifices–and, within years, she sold it to L’Oreal for a reported $500 million. A non-compete agreement meant Ko was locked out of the beauty industry for five years, a time during which she learned some of her most important life and entrepreneurial lessons–including how to stop worrying and focus on finding simple solutions to her own complex problems. Host Christine Lagorio-Chafkin explores with Ko how she coped with selling her company, what she created (sunglasses company Perverse) in the meantime, and how she’s back with a new company that’s creating brand new cosmetics in partnership with influencers, celebrities, and designers. It’s called Bespoke Beauty Brands, and for Toni, building it came with its own new learning curve.

Trinity Mouzon Wofford founded superfood company Golde in 2017, and has grown it into a national brand that sells its drink mixes and face-mask blends direct-to-consumer and in national retailers like Target. She bootstrapped the business for years, doing everything from formulation to sales herself. One skill that helped her along the way was her ability to connect with others–to see things from a different perspective. She explains the radical empathy it takes to truly connect with someone new–even if it’s through a video screen.

There’s Silicon Valley’s playbook…and then there’s Trinity Mouzon Wofford’s radical bootstrapping. The founder of Golde, the maker of superfood powders that can be blended to make lattes or facemasks, and which is sold at Target and Goop, as well as direct-to-consumer. Trinity explains how she built her company herself, mixing turmeric lattes in her kitchen, and pounding the pavement of New York City trying to get her self-designed pouches of blends onto cafe shelves. As a super-small, scrappy, brand, growth was happening naturally–online, and off–and the level of control she had over it was not something she wanted to give up. Trinity tells host Christine Lagorio-Chafkin about how she reacted when investors came calling–and when major retailers proposed deals. 

Delane Parnell’s $400 million startup, PlayVS, builds a platform on which high school students can compete against one another in team-based video games, also known as esports. Host and “Ahead of the Game” author Kevin Ryan talks with Parnell about his journey from a violence-ridden neighborhood on Detroit’s west side to building one of the most important companies in the rapidly growing gaming industry.

Payal Kadakia, the founder of Classpass, which was valued at $1 billion before its acquisition by Mindbody in 2021, wasn’t always great at keeping track of her priorities. Sure, she had a calendar, and a schedule–but sometimes the big-picture goals would get pushed aside. She came up with a 20-minute-a-week way to stay focused–by setting her priorities for the week. And, as a bonus, she finds the whole thing pretty meditative.

Growing up in New Jersey, Payal Kadakia found a passion for Indian dance. As an adult living in New York City, she founded her own dance troupe, Sa Dance. But when it came to finding fitness classes, she was at a loss. She created a boutique-class-search-engine–which went through many, many, iterations, before becoming the $1 billion company ClassPass. Christine Lagorio-Chafkin speaks with Payal about all the ups and downs along the way to building one of New York City’s unicorns–and her difficult decision to step back from the CEO role she’d held for so long in 2017. Along the way, she learned to not hide her feelings, or her passions, in the workplace–and instead, bring her full self to her job.