Health & Veritas

Howie and Harlan are joined by David Fiellin, a Yale internist and an expert in addiction medicine. Harlan reports on a new study showing a surprising benefit from a daily multivitamin; Howie explains how a 1994 law is fueling hype around an untested herbal supplement for weight loss.  Links: “Multivitamin Supplementation Improves Memory in Older Adults: A Randomized Clinical Trial” Earlham College: Mission, Principles, and Values “What Ozempic Reveals About Desire” Substance Abuse and Mental Health Services Administration: Buprenorphine National Institute on Drug Abuse: Naloxone DrugFacts CDC: Understanding the Opioid Overdose Epidemic “The Truth About ‘Nature’s Ozempic’” Dietary Supplement Health and Education Act of 1994 Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Abbe Gluck of Yale Law School to discuss how law shapes the health of Americans. Harlan explains how flaws in data privacy affect patients; Howie gives an update on the millions losing their Medicaid coverage, often despite qualifying for the program. Links: Harlan Krumholz: “In the US, patient data privacy is an illusion” “Medical Legal Partnerships” “A prospective cohort study examining exposure to incarceration and cardiovascular disease (Justice-Involved Individuals Cardiovascular Disease Epidemiology – JUSTICE study): a protocol paper” Abbe Gluck: COVID-19 and the Law: Disruption, Impact and Legacy “Explaining Litigation Challenging the ACA’s Preventive Services Requirements: Braidwood Management Inc. v. Becerra” “Abortion pill case: where does the lawsuit against the pill currently stand” “Chevron case: Supreme Court could take sledgehammer to agency power” “SAFFORD UNIFIED SCHOOL DIST. #1 v. REDDING (No. 08-479)” “What Do the Early Medicaid Unwinding Data Tell Us?” “As Medicaid Purge Begins, ‘Staggering Numbers’ of Americans Lose Coverage” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Sandeep Jauhar, a cardiologist and the author, most recently, of the memoir My Father’s Brain: Life in the Shadow of Alzheimer’s. Harlan reports on new research about the timing of blood thinners for stroke patients with atrial fibrillation; Howie checks in on two physician groups that were acquired by private equity investors earlier this year and are now facing bankruptcy.  Links: “Early versus Later Anticoagulation for Stroke with Atrial Fibrillation” Sandeep Jauhar: Heart: a History  Sandeep Jauhar: “How Would You Feel About a 100-Year-Old Doctor?” Sandeep Jauhar: My Father’s Brain: Life in the Shadow of Alzheimer’s “The Dutch Village Where Everyone Has Dementia” National Institute on Aging: What Causes Alzheimer's Disease?  “KKR-Backed GenesisCare Preps for Bankruptcy Filing Within Days” “KKR-Backed Envision Healthcare Plans Chapter 11 Bankruptcy Filing” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan welcome Yale’s Albert Ko back to the podcast to discuss the state of the COVID-19 pandemic and his career as an infectious disease specialist and public health researcher. Harlan reports on a breakthrough in pacemaker technology; Howie reflects on the complex relationship between obesity, social media, and mental health for young people.  Links: “A Dual-Chamber Leadless Pacemaker” Health & Veritas, Ep. 14: Albert Ko: A Wider View of COVID-19 “What’s Going On With Covid Right Now?” Weill Cornell Medical School: Warren Johnson Berkeley Public Health: Lee Riley WHO: Social Determinants of Health “The role of dieting, happiness with appearance, self-esteem, and bullying in the relationship between mental health and body-mass index among UK adolescents: a longitudinal analysis of the Millennium Cohort Study” “Surgeon General Issues New Advisory About Effects Social Media Use Has on Youth Mental Health” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Joseph Sakran, whose career as a trauma surgeon and advocate grew out of his own experience with gun violence. Harlan discusses his new study enumerating the vast scale of excess deaths among Black Americans; Howie reports on improvements in the insurance rate, nearly a decade after the Affordable Care Act went into effect.  Links: Harlan Krumholz: “Excess Mortality and Years of Potential Life Lost Among the Black Population in the US, 1999-2020” “Shot in the neck at 17, this is the trauma surgeon now leading doctors against gun violence and the NRA” Written Testimony of Joseph Sakran—U.S. House Judiciary Committee, February 6, 2019 “Doctors See the Wreckage of Gun Violence Every Day. We've Had Enough” “In 2019, Congress Pledged Millions to Study Gun Violence. The Results Are Nearly Here.” “U.S. gun deaths disproportionately high” “The State of U.S. Health Insurance in 2022” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Josh Geballe, a Yale SOM graduate who serves as managing director of Yale Ventures, Yale’s initiative overseeing the translation of research into impactful new companies. Harlan reports from the debate on AI in medicine; Howie reflects on the FDA’s approval process for an over-the-counter birth control pill.  Links: “Iwasaki to Receive Else Kröner Fresenius Prize Supporting Research Into Long COVID and Similar Conditions” “As Covid Emergency Ends, U.S. Response Shifts to Peacetime Mode” “ChatGPT - Reshaping medical education and clinical management” “Performance of ChatGPT on USMLE: Potential for AI-assisted medical education using large language models” “Artificial Hallucinations in ChatGPT: Implications in Scientific Writing” Yale Ventures Tsai Center for Innovative Thinking at Yale “The economic transformation: What would change in the net-zero transition” “Joint Meeting of the Nonprescription Drugs Advisory Committee and the Obstetrics, Reproductive, and Urologic Drugs Advisory Committee May 9, 2023 – May 10, 2023” FDA | May 9-10, 2023: Joint Meeting of the Nonprescription Drugs Advisory Committee and the Obstetrics, Reproductive and Urologic Drugs Advisory Committee Meeting Announcement “F.D.A. Advisers Weigh Allowing First U.S. Over-the-Counter Birth Control Pill” Food and Drug Administration | Prescription-to-Nonprescription (Rx-to-OTC) Switches “Over-the-counter sales of statins and other drugs for asymptomatic conditions” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Amanda Skinner, a Yale SOM graduate who leads Planned Parenthood of Southern New England. Harlan reflects on the potential and the dangers of artificial intelligence; Howie reports on an advisory from Surgeon General Vivek Murthy about the public health impact of loneliness and social isolation.  Links: “Five Alumni Named 2021-22 Donaldson Fellows” “Idaho hospital to stop delivering babies as doctors flee over abortion ban” “Abortion providers in the United States: expanding beyond obstetrics and gynecology” “‘The Godfather of A.I.’ Leaves Google and Warns of Danger Ahead” “Is artificial intelligence advancing too quickly? What AI leaders at Google say” “ChatGPT may have better bedside manner than some doctors, but it lacks some expertise” “Surgeon General: We Have Become a Lonely Nation. It’s Time to Fix That.” “Our Epidemic of Loneliness and Isolation” “Good genes are nice, but joy is better” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Elizabeth Arleo, a radiologist with a focus on breast imaging and the author of First, Eat Your Frog: And Other Pearls for Professional Working Mothers. Harlan reports on the state of AI in healthcare; Howie reflects on the epidemic of lung injuries from vaping.  Links: “Epic, Microsoft bring GPT-4 to EHRs” Harlan Krumholz: “Foundation models for generalist medical artificial intelligence” “Is artificial intelligence advancing too quickly? What AI leaders at Google say” Elizabeth Arleo: First, Eat Your Frog: And Other Pearls for Professional Working Mothers Howard Forman: “Why don't female medical students choose diagnostic radiology? A review of the current literature”  American Cancer Society: American Cancer Society Recommendations for the Early Detection of Breast Cancer CDC: Outbreak of Lung Injury Associated with the Use of E-Cigarette, or Vaping, Products “Juul Reaches $462 Million Settlement With New York, California and Other States” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Megan Ranney, who will become the dean of the newly independent Yale School of Public Health later this year. Harlan reflects on the research that is helping us understand aging at a cellular level; Howie discusses a new study that he co-authored which examines the costs that make it harder for many mothers to breastfeed.  Links: “Accelerated Epigenetic Aging Is Associated with Multiple Cardiometabolic, Hematologic, and Renal Abnormalities: A Project Baseline Health Substudy” Outlive by Peter Attia with Bill Gifford “Megan Ranney named dean of Yale School of Public Health” “Yale School of Public Health to become self-supporting, independent school” Megan Ranney: “To prevent gun injury, build better research” Megan Ranney: “We need more research on guns. Here are 5 questions we can answer.” Howard Forman: “No such thing as a free lunch: The direct marginal costs of breastfeeding” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Cary Gross, professor of medicine and public health and director of the National Clinician Scholars Program at Yale, to discuss his creative approach to research and his sometimes contrarian stances on cancer screening and not holding medical conferences in states that ban abortion. Harlan explains the nuances of new research about mortality risks tied to weight loss in older adults; Howie discusses his concerns over courts interfering with FDA drug approval processes arising from two cases tied to the medical abortion pill mifepristone. Links: “The Relation between Funding by the National Institutes of Health and the Burden of Disease” “Allocation of National Institutes of Health Funding by Disease Category in 2008 and 2019” “Too Many Older Patients Get Cancer Screenings” National Cancer Institute | National Cancer Act of 1971 “Holding Medical Professional Society Scientific Meetings Only in States That Protect Abortion Rights—Clinical and Ethical Considerations” “Associations of Change in Body Size With All-Cause and Cause-Specific Mortality Among Healthy Older Adults” “Judge Invalidates F.D.A. Approval of the Abortion Pill Mifepristone” “Democratic state attorneys general sue Biden administration over abortion pill rules” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.