DTx Podcast with Eugene Borukhovich

Have you heard? On August 22, Mahana Therapeutics announced a distribution and marketing partnership with Bayer’s consumer health division. This partnership unites Mahana’s proficiency in digital therapeutic advancement with Bayer’s commitment to empowering individuals through cutting-edge digital solutions, all aimed at enabling greater personal health control. The full press release is linked below.In light of this, we’re bringing you this replay episode with Simon Levy, CEO and Co-founder, and Ann Montgomery, Chief Product Officer at Mahana.In their own words, Mahana develops digital treatments for people living with chronic health conditions, and their first treatment, Mahana for IBS, is now available as an FDA-cleared app.In this episode, we cover: The founding story and funding journey of Mahana Complexities of the end to end patient experience The freemium model and how that translates into a PDT Evidence generation and FDA clearance process Scaling plans for PDTs Guest Links and Resources: Press Release about the Mahana and Bayer partnership Connect with Simon Levy on LinkedIn Connect with Ann Montgomery on LinkedIn Visit Mahana.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to:> Presenting Partner: Amalgam Rx> Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion PharmaFollow Digital Health Today:Browse Episodes | Twitter | LinkedIn | Facebook | InstagramFollow Health Podcast Network:Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Brian Wallace, CMO and Co-Founder of Calmsie. Calmsie in their own words are empowering children to develop emotional resilience from an early age. Calmsie creates engaging DTx video games designed to improve outcomes for children with depression and anxiety.In this episode, we cover: Translating addiction science to treat depression and anxiety in children The origin story and funding journey to Calmsie Parent and child experiences using the gamified program Emotional resilience training for prevention of mental health issues How the Calmsie video game affects the brain Evidence generation and deciding on PDT vs non-PDT routes The free workbook helping children understand the war in Ukraine Guest Links and Resources: Connect with Brian Wallace on LinkedIn Visit calmsie.ai YourCoach Health: Deep Dive Into Adolescent Health Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to:> Presenting Partner: Amalgam Rx> Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus HealthFollow Digital Health Today:Browse Episodes | Twitter | LinkedIn | Facebook | InstagramFollow Health Podcast Network:Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this special feed drop hear the first episode of Emerging Medtech Today, hosted by Henry Peck and powered by LSI. The Emerging Medtech Today podcast offers a unique opportunity to gain valuable insights from industry leaders who are building breakthrough businesses that are moving medtech forward.Join Henry as he engages in captivating conversations with innovators and investors who are at the forefront of medtech. Discover the strategies, technologies, and ideas that are shaping the future of healthcare. In this episode Henry Peck speaks with Diana Saraceni and Alessio Beverina, co-founders and managing directors of Panakes, a venture capital firm that’s helping to build the next generation of game-changing technologies companies in the field of Life Sciences.Diana brings 23 years of venture capital experience and previously co-founded another successful venture capital firm called 360 Capital. Alessio, with an engineering background, co-founded Panakes in 2015 after working as a research engineer at Sofinnova Partners.Throughout the episode, Diana and Alessio provide valuable insights into the evolving landscape of medtech investing, shedding light on the complexities, challenges, and opportunities in the field.Topics include: Current market conditions and challenges faced by companies in medtech Key learnings from Panakes’ first fund which focused on medtech and raised €75 million Strategies for the newly raised second fund, with plans to expand its focus to include biotech and opportunities where medtech and biotech converge The impact of regulatory changes, particularly the MDR (Medical Device Regulation) shift and the increasing prioritization of FDA approval in Europe   Navigating the evolving landscape of digital health and its intersection with artificial intelligence (AI) Health tech and digital health opportunities in Europe compared to the US A reflection on the future of healthcare innovation Diana and Alessio’s upcoming participation at the LSI Europe ‘23 conference in September, where they will discuss these topics in greater detail And more!Transcript of episodeGuest links and resources: Connect with Diana Saraceni: LinkedIn Connect with Alessio Beverina: LinkedIn | Twitter Panakes Connect with Henry: Twitter | LinkedIn Learn more about LSI Sign up for LSI Europe '23 Connect with LSI:Browse Episodes | Twitter | LinkedIn | Facebook | InstagramConnect with Health Podcast Network:Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from David Kim, Managing Director at DigiTx Partners. In their own words DigiTX Partners is a venture firm focused on investing in and supporting early stage startup companies in the digital health space. Launched in 2016 as a joint venture by Astellas Pharma And MPM Capital, DigiTx Partners remains one of a few venture funds exclusively dedicated to the digital health space. In 2018, Astellas continued its endeavor in digital health by forming the Rx Plus Digital Fund with DigiTx Partners as its investment manager.In this episode, we cover: What are the challenges faced by digital therapeutics in terms of distribution and clinical workflow? What hypothesis does DigiTx on DTx? What are the benefits of standalone vs drug+? Are DigiTx tracking any other modalities? What lessons have DigiTx learned so far? What will be the drivers for new capital injections in DTx especially? What are investors looking for ? What will the drivers of success going forward be for DTx?  How will the role of doctors, nurse & pharmacists change in order for the industry overall to scale PDT's? Guest Links and Resources: Connect with David Kim on LinkedIn Visit DigiTx Partners Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to:> Presenting Partner: Amalgam Rx> Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus HealthFollow Digital Health Today:Browse Episodes | Twitter | LinkedIn | Facebook | InstagramFollow Health Podcast Network:Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Sean Khozin, Senior Partner at the investment firm Braven Partners. He focuses on advancing in innovations at the intersection of biology, technology and AI. Sean was previously the CEO of CancerLinQ and the Global Head of Data Strategy and Data Science at Johnson & Johnson. He had a successful tenure in the US federal government as the associate director of FDA’s Oncology Center of Excellence and the founding executive director of FDA INFORMED, a data science and technology incubator he established under special authorities from the US department of health and human services.Topics include: How are Braven Partners incubating and supporting minimally viable ecosystems of companies that can make a difference? What are the goals of the Alliance for Artificial Intelligence in Healthcare? How can digital therapeutics developers ensure effective reimbursement for their products in the healthcare industry? How is the ethos of AI in healthcare speaking to a culture that is focused on safety without compromising innovation? How do we demystify new tools and technologies such as AI? How does the FDA think about regulating AI? What can digital therapeutic manufacturers companies, entrepreneurs and trailblazers learn from the Alliance for Artificial Intelligence in Healthcare (AAIH)? Guest Links and Resources: Connect with Sean Khozin on LinkedIn Visit Braven Partners Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to:> Presenting Partner: Amalgam Rx> Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus HealthFollow Digital Health Today:Browse Episodes | Twitter | LinkedIn | Facebook | InstagramFollow Health Podcast Network:Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Benjamin Alouf, MD, Chief Medical Officer at Limbix. In their own words, Limbix is the first digital therapeutic for adolescent depression.  Big Health, the leading provider of non-drug digital treatments for mental health, has now acquired Limbix. In addition to health care providers, SparkRx will be made available to Big Health’s employer, public sector, health systems and health plan customers, and through the company’s strategic distribution agreements with pharmacy benefit managers (PBMs), significantly increasing nationwide access.In this episode, we cover: Origin of the company and story behind the name 'Limbix' The funding journey and key milestones achieved The choice to focus on the young adult population in particular Patient experience with SparkRx Defining good patient engagement in adolescent mental health Evidence generation and FDA submission process Business hypthothesis and scaling plan The future of the PDT market Guest Links and Resources: Connect with Benjamin Alouf, MD on LinkedIn Visit Limbix.com Episode PDF Big Health Expands into Adolescent Mental Health Through Acquisition of Limbix Host Links: Eugene Borukhovich: Twitter | LinkedIn Chandana Fitzgerald, MD: Twitter | LinkedIn YourCoach.health: Website | Twitter Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to:> Presenting Partner: Amalgam Rx> Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus HealthFollow Digital Health Today:Browse Episodes | Twitter | LinkedIn | Facebook | InstagramFollow Health Podcast Network:Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Eddie Martucci, co-founder and CEO of Akili. In their own words, Akili Interactive is a leading digital health company combining scientific and clinical rigor with ingenuity of the tech industry to reinvent medicine.In this episode, we cover: What factors have led to the increase in market demand for non-drug treatments for adult ADHD? How does Akili Interactive's prescription video game product, EndeavorRx, differ from traditional behavioral therapy for ADHD? What are the advantages and challenges of developing a digital therapeutic product that is available over-the-counter (OTC) without a prescription? How does the insurance coverage landscape impact the availability and adoption of digital therapeutics? What strategies does Akili Interactive employ to address the lack of awareness about digital therapeutics and their potential benefits? How does the user interface and experience of the EndeavorRx companion app, EndeavorRx Insight, contribute to higher compliance and better outcomes for families? How has Akili Interactive adapted and improved their commercial platform for scaling the distribution of their products? What advice does Eddie Martucci have for health executives? Guest Links and Resources: Connect with Eddie Martucci on LinkedIn Visit Akili Season 1 Episode: Akili’s Revolutionary Digital Therapeutic with Eddie Martucci Co-Founder/CEO of Akili Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to:> Presenting Partner: Amalgam Rx> Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus HealthFollow Digital Health Today:Browse Episodes | Twitter | LinkedIn | Facebook | InstagramFollow Health Podcast Network:Browse Shows | LinkedIn | Twitter | Facebook | Instagram

Let's face it, entrepreneurship is tough. While we're certainly seeing a much needed correction in the market this does not make it easier for any trailblazers out there. Sales cycles have slowed down. Decision making became even less transparent. And finally, funding became a numbers game. Now add to all of this, some recent bankruptcies and your head starts spinning. So what should a Digital Therapeutics entrepreneur do? Since we have the pleasure of hosting dozens upon dozens of leaders in the industry, we decided to put together a special episode with their advice to the awesome entrepreneurs out there.Guest Links and Resources: Connect with Acacia Parks on LinkedIn Visit Liquid Amber Connect with Ameya Phadke, Ph.D on LinkedIn Visit Chiesi Group Connect with Omar Manejwala, MD on LinkedIn Visit Dario Health Connect with Benjamin Alouf, MD on LinkedIn Visit Limbix Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to:> Presenting Partner: Amalgam Rx> Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus HealthFollow Digital Health Today:Browse Episodes | Twitter | LinkedIn | Facebook | InstagramFollow Health Podcast Network:Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Jennifer Goldsack, CEO of Digital Medicine Society (DiMe). In their own words, DiMe is a global non-profit and the professional home for all members of the digital medicine community.In this episode, we cover: The origin and mission of DiMe Defining digital health, digital medicine and digital therapeutics Collaborating with the Digital Therapeutics Alliance Stakeholder management for patients and pharma The payer contracting framework Working across the healthcare ecosystem DiMe's approach to the science behind digital medicine and digital measurement products Guest Links and Resources: Connect with Jennifer Goldsack on LinkedIn Visit dimesociety.org Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to:> Presenting Partner: Amalgam Rx> Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus HealthFollow Digital Health Today:Browse Episodes | Twitter | LinkedIn | Facebook | InstagramFollow Health Podcast Network:Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Joe Perekupka, CEO of Freespira. In their own words Freespira is 'the only medication-free, FDA-cleared digital therapeutic treatment proven to significantly reduce or eliminate symptoms of panic disorder, panic attacks and post-traumatic stress disorder in just 28 days.'In this episode, we cover: The founding story of Freespira The user experience from prescription to daily use The role of health coaches within Freespira Identifying potential candidates for Freespira The current landscape for panic disorder treatment and research into MDMA-assisted therapies Evidence generation to FDA approval journey Evolving pricing models The scope of PTSD across the US Guest Links and Resources: Connect with Joseph Perekupka on LinkedIn Visit freespira.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to:> Presenting Partner: Amalgam Rx> Sponsors: LSI | Bayer G4A | Lindus HealthFollow Digital Health Today:Browse Episodes | Twitter | LinkedIn | Facebook | InstagramFollow Health Podcast Network:Browse Shows | LinkedIn | Twitter | Facebook | Instagram