Scott Aaronson, Quantum computing expert, discusses the hype and reality of quantum computing, potential for breaking cryptography, tasks where quantum computers excel, legitimacy of current quantum computing solutions, fighting misinformation, and career prospects in the field.

Joep Meindertsma, an AI safety expert, debates whether AI development should be paused for safety concerns and discusses the risks associated with advanced AI models like GPT-4. The podcast delves into the ethical dilemmas of AI advancement, emotional turmoil over AI risks, and the need for responsible governance in managing the potential dangers of superintelligent AI.

Will MacAskill discusses the SBF/FTX scandal, addressing red flags, Sam's personality, and EA principles. They explore AI dangers, leadership lessons, and the future of Effective Altruism.

Kevin Adler, an expert in homelessness, discusses the complexities of addressing homelessness in big cities. They explore language use, mental health, substance abuse, and the impact of personal relationships on understanding homelessness. They also touch on the challenges of accessing psychiatric care, basic income initiatives, and the importance of community support in addressing homelessness and addiction issues.

Body language expert Blake Eastman discusses quantifying body language, poker 'tells,' universal facial expressions, group dynamics in video calls, dating mistakes, charisma indicators, dealing with trolls, and micro-expressions validity.

Entrepreneur and author Derek Sivers explores the complexities of truth and belief systems, discussing the significance of distinguishing objective truths from subjective opinions, navigating moral ambiguity in relationships, and choosing beliefs that lead to personal growth. The podcast dives into the challenges of finding unbiased perspectives, understanding multiple viewpoints, and embracing individuality and independent thinking.

The podcast explores widening moral circles to include insects, AI, and plants. It delves into factory farming's ethical implications and consciousness definitions. Discussions touch on abortion, free will, and panpsychism. Ethics, intrinsic values, and Valuism are also debated with a focus on doing good amidst uncertainties.

Explore the idea of building a high-impact career with Benjamin Hilton, focusing on choosing the right problems to solve, leveraging strengths, predicting the future, and finding meaning in career choices. Learn about the impact formula, maximizing impact through leverage and problem-solving strategies, and balancing belief updates to navigate economic growth with cooperation and goodwill.

The host discusses his key takeaways after 200 episodes, focusing on improving conversations, updating views, and asking great questions. Listeners are thanked for their support, and feedback is encouraged through a new survey.

Can a single psychological intervention change a life? Jessica Schleider discusses brief interventions for mental health issues. Comparing teen and adult responses, the impact of turning points, and the synergy of qualitative and quantitative research methods. Exploring regression to the mean, effect sizes in interventions, and reflections on change and economic impact.