Clearer Thinking with Spencer Greenberg Should we try to live forever? (with Ariel Zeleznikow-Johnston)
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Aug 22, 2025 
In this captivating discussion, neuroscientist Ariel Zeleznikow-Johnston shares insights on human longevity and how it compares to other species. He examines the fascinating evolutionary trade-offs in lifespan and reproduction, while speculating on future technologies like stasis and cryonics. The conversation delves into the fluid concept of death, questioning traditional definitions and addressing consciousness and identity in light of technological advancements. Zeleznikow-Johnston challenges us to rethink our relationship with life and death, raising intriguing philosophical questions along the way.
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Longevity Trades Off With Early Reproduction
- Lifespan trades off with speed of reproduction due to genes affecting multiple traits.
- Antagonistic pleiotropy means genes favoring early reproduction can reduce later-life longevity.
Evolution Lags Behind Modern Medicine
- Human lifespan expanded as early-life mortality fell, shifting evolutionary pressure toward later reproduction.
- Genetic evolution for longer life is slow and lags behind recent medical improvements.
Preservation Is Easier Than Revival
- Preservation (stasis) and revival are distinct challenges; preservation is easier than revival.
- Current preservation might plausibly retain structure enough to allow future revival decades hence.
