Send us a textIn this insightful episode, I am joined by Chris Mirabile, a visionary in the field of longevity and the founder of Novos, a company at the forefront of combating aging through science-backed strategies and natural innovations. Chris shares his personal journey of health challenges and triumphs, which led him to a lifelong commitment to understanding the science of aging and optimizing human potential. His mission to bridge the gap between cutting-edge biotech and accessible health solutions has made him a trailblazer in the field of longevity.Our conversation dives deep into the 12 hallmarks of aging, a revolutionary framework for understanding the biological mechanisms behind the aging process.  We also explore actionable lifestyle changes and the synergistic role of nutrition, supplements, and mindfulness in enhancing healthspan and lifespan. From the potential of senescent cell management to the transformative power of personalized health strategies, Chris provides valuable insights for anyone seeking to live a longer, healthier, and more vibrant life. Tune in to uncover the secrets to slowing aging and unlocking your full potential.Looking to discover your science and optimize your life?APPLY FOR HEALTH OPTIMIZATION COACHINGhttps://coaching.knowyourphysio.org/Links Mentioned in Today’s Episode:Click HERE to save on BiOptimizers MagnesiumKey Points From This Episode: Health transformation through adversity [00:01:22]Health transformation through adversity [00:05:06]Defining aging at the cellular level [00:09:41]Novos Longevity Diet Optimization [00:12:29]Nutrient inadequacies in modern diets [00:17:04]Testing for vitamin levels [00:20:29]Iron levels and health risks [00:24:51]12 hallmarks of aging [00:29:22]Cellular senescence and longevity [00:31:51]Fasting mimetics and longevity [00:35:54]Trace doses of lithium benefits [00:39:44]Telomere shortening and lifespan [00:45:10]Stem cell exhaustion and aging [00:48:17]Microbiome dysbiosis and health [00:51:31]Synergistic effects of formulas [00:56:48]Lifestyle strategies affecting aging [01:03:12]Nervous system's impact on supplements [01:06:07]Longevity accessibility for everyone [01:10:34]Slowing down aging [01:12:17] SlowMyAgeWebsiteNovos LabsWebsiteNovos Life AppFree mobile app available on iOS and Android, featuring a biological age test, personalized lifestyle guidance, and integrated LLM (AI-powered guidance).PeopleChris MirabileLinkedIn ProfileInstagram (@slowmyage)Andrés PreschelLinkedIn ProfileInstagram (@andrespreschel)Twitter (@andrespreschel)Dan BuettnerWikipediaBluSupport the show

Send us a textIn this episode, I’m stepping into the guest seat as Drew Shuman and I dive into the science and strategies behind optimizing health and performance. We explore how personalized practices, evidence-based biohacking, and a deeper understanding of your own physiology can transform your approach to well-being. This conversation is packed with actionable insights to help you take charge of your health journey.We cover a wide range of topics, including the cognitive and physical benefits of creatine, the role of carbohydrates in performance, and how to maximize VO2 max through strategic training. Drew and I discuss the importance of aligning your habits with your unique needs, demystifying complex health concepts, and providing practical advice for anyone looking to elevate their physical and mental performance.This episode is a must-listen for those curious about the intersection of science and health optimization. Whether you’re starting your journey or looking for advanced strategies, you’ll find plenty of inspiration and tools to create lasting change. Tune in to learn how to unlock your potential and embrace a healthier, more energized life.Looking to discover your science and optimize your life?APPLY FOR HEALTH OPTIMIZATION COACHINGhttps://calendly.com/andrespreschel/intro-call-with-andresLinks Mentioned in Today’s Episode:Click HERE to save on BiOptimizers MagnesiumKey Points From This Episode:VO2 max and longevity [00:05:28]Energy currency of the body [00:09:02]Carbohydrate consumption and performance [00:13:39]Ketogenic diet benefits and concerns [00:15:05]Carbohydrates and exercise benefits [00:21:03]Glycemic index and exercise timing [00:23:16]Leptin signaling and obesity cycle [00:29:16]Fasted training effectiveness [00:30:48]Carbohydrate intake for performance [00:35:45]VO2 max and training adaptations [00:39:41]High altitude training benefits [00:42:19]Creatine: Evolving perceptions and benefits [00:48:07]Muscle gain versus fat loss [00:56:07]Creatine's impact on mood [00:59:22]Managing light exposure for sleep [01:00:41]Morning hydration and sunlight [01:05:02]Neuroplasticity and personal transformation [01:09:36]Leveraging physiological mechanisms for health [01:11:17]PeopleDrew ShumanInstagramPlacesLongevity Center, West Palm BeachOfficial WebsiteGreenfield Water SolutionsOfficial WebsiteEveryday Dose CoffeeProduct WebsiteRelight Electrolytes by Redmond Real SaltProduct WebsiteSupport the show

Send us a textIn this compelling episode, I sit down with Dr. Benjamin Kosubevsky, an innovative expert in integrative medicine and detoxification therapies. As a specialist in heavy metal detoxification and hyperoxygenation treatments, Dr. Kosubevsky is transforming the way we approach chronic health issues tied to toxic exposures. His mission at the Longevity Center is not only to improve patient health but to make cutting-edge therapies like chelation and Eboo available and affordable for everyone, empowering individuals to tackle the environmental challenges impacting modern wellness.Our conversation delves into Dr. Kosubevsky’s deep-rooted passion for alternative medicine and his journey from traditional medical training to the pioneering, hands-on work he does today. He shares insights into the mechanics of chelation and hyperoxygenation, revealing how they remove accumulated heavy metals, reduce inflammation, and support whole-body healing. This episode is essential listening for anyone navigating fatigue, brain fog, or chronic inflammation, or simply curious about innovative paths to optimal wellness. Tune in to explore the profound potential of therapies that help restore the body’s natural resilience and discover how to take control of your own health journey.Looking to discover your science and optimize your life?APPLY FOR HEALTH OPTIMIZATION COACHINGhttps://calendly.com/andrespreschel/intro-call-with-andresLinks Mentioned in Today’s Episode:Click HERE to save on BiOptimizers MagnesiumKey Points From This Episode:Hyperoxygenation benefits for health [00:07:27]Mercury's impact on health [00:12:51]Molybdenum deficiency and heavy metals [00:14:37]Selenium's role in mercury protection [00:21:33]Foods that help chelate mercury [00:22:42]Hemochromatosis and iron levels [00:26:39]Mercury and neurological health impacts [00:30:01]Bioaccumulation of heavy metals [00:38:28]Ozone treatment advancements [00:46:41]Cost-effective chelation treatments [00:51:25]Vaccines and heavy metals [00:54:48]Heavy metals in everyday products [00:57:15]Chelation and oxygen benefits [01:02:18] PeopleDr. Benjamin KosubevskyLinkedIn ProfileInstagramDr. Wesley SmithUniversity of Miami ProfilePlacesLongevity CenterOfficial WebsiteProducts and ReferencesEDTA Chelation TherapyWebMD ResourceDMPS Chelation TherapyDMPS ChelationIV Ozone TherapyInformative ArticleSpirulina and Chlorella SupplementsInformative ArticleHyperoxygenation TherapyInformative Article:Molybdenum Deficiency and MercurySupport the show

Send us a textIn this compelling episode, I sit down with Eli Wininger, an ultramarathon runner, former IDF Special Forces commander, and a profound advocate for resilience and purpose. Known for his feats of endurance, Eli’s journey takes us from the battlefield to the grueling landscapes of ultramarathons, revealing the depth of his mental and physical fortitude. His latest achievement—a 251-mile race in Moab dedicated to each of the hostages taken on October 7th—demonstrates how he channels his experiences into a mission much larger than himself.Our conversation delves into the mindset of an endurance athlete and the emotional significance behind Eli’s relentless pursuit of challenges. Eli opens up about the importance of finding a powerful "why" to fuel our actions, whether that be through personal growth, health, or setting an example for others. This episode is a must-listen for anyone seeking to deepen their understanding of perseverance, purpose, and the power of a committed mind. Eli’s journey is both inspiring and humbling, providing a roadmap for pushing beyond self-imposed boundaries. Looking to discover your science and optimize your life?APPLY FOR HEALTH OPTIMIZATION COACHINGhttps://calendly.com/andrespreschel/intro-call-with-andresLinks Mentioned in Today’s Episode:Click HERE to save on BiOptimizers MagnesiumKey Points From This Episode:Experience in conflict. [00:06:09]Humility in warrior mindset. [00:12:51]Intrinsic motivation in training. [00:17:27]Neuroplasticity through challenging experiences. [00:24:24]Embracing the pain cave. [00:30:08]Collective joy through physical activity. [00:39:44]The benefits of pushing limits. [00:46:11]Breath work and athletic performance. [00:52:10]Running for a greater purpose. [01:02:05]Race strategy and aid stations. [01:08:47]Finding purpose in suffering. [01:13:39]The importance of breathing. [01:19:04]Leadership accountability and credit. [01:22:45]Mission for the hostages. [01:25:04] PeopleEli WiningerInstagramDavid GogginsInstagramDr. Kelly McGonigalLinkedIn Peter Attia, MDOfficial WebsitePlacesBring Them Home Now FoundationOfficial WebsiteIDF Special Forces - Sayeret EgozWikipedia: Sayeret EgozLeadville Race SeriesOfficial Website: Leadville Race SeriesBooks and ReferencesHow to Make Stress Your FriendTED TalkNeuroplasticityInformative Article: Neuroplasticity - NIHWHOOPOfficial Website: WHOOPRed Light TherapySupport the show

Send us a textIn this insightful episode, I sit down with Alexandra Sheth, a Master of Public Health in Dietetics and Nutritional Sciences and an expert in nervous system regulation. With a background in neuroscience and a passion for blending Western science with Eastern practices, Alexandra has carved a unique path in health and wellness. Her approach merges the tangible with the intangible, creating a holistic framework that embraces both the measurable aspects of health and the deeper, more subtle dimensions of our inner worlds.Our conversation explores Alexandra's transformative journey from conventional medicine to a holistic approach that emphasizes the synergy between mind, body, and energy. We delve into her experiences with somatic breathwork, acupuncture, and functional nutrition, uncovering how these practices can dissolve internal stagnation and restore balance. Whether you’re seeking to deepen your connection to your body, cultivate resilience, or integrate holistic practices into your daily life, Alexandra’s journey and expertise provide a compelling roadmap to living with purpose and intention. Tune in and discover how aligning with the rhythm of life’s seasons can lead to lasting health and fulfillment.Key Points From This Episode:East meets West healing approach. [00:06:14]Muscle testing and holistic health. [00:13:53]Breathing as effective therapy. [00:19:18]Responsibility for modern detachment. [00:28:48]Brain vs. Mind distinction. [00:38:35]Interoception and wearable devices. [00:45:10]Movement, mindfulness, and meals. [00:52:19]Trauma's effect on the body. [01:02:09]Community as a source of strength. [01:09:35]Costa Rica retreat adventure. [01:11:26] Looking to discover your science and optimize your life?APPLY FOR HEALTH OPTIMIZATION COACHINGhttps://calendly.com/andrespreschel/intro-call-with-andresLinks Mentioned in Today’s Episode:Click HERE to save on BiOptimizers MagnesiumPeopleAlexandra ShethInstagram ProfileWebsite: Sheth StudiosGabor MatéOfficial WebsitePlacesHanu HealthInstagram ProfileModern OmOfficial WebsiteSupport the show

Send us a textIn this special episode, I switch roles and step into the guest seat, giving you a behind-the-scenes look into my own journey—from biohacker and performance coach to someone deeply passionate about living life with intention. I share the experiences that have shaped my philosophy, from my love of spearfishing and being in nature to blending science with real-world application to help others unlock their full potential.I also talk about the power of key performance indicators like HRV and VO2 max, and how they’ve transformed not only my life but the lives of my clients. This conversation touches on the importance of balancing data with intuition, the lessons I’ve learned through coaching, and the way I strive to integrate nature, science, and human connection.If you’re interested in how to elevate your health and performance, or simply curious about the personal side of my journey, this episode is for you. I share insights from my own life, the science I live by, and the small but meaningful changes anyone can make to live a healthier, more intentional life. Join me as I open up about the philosophy that drives me—both on and off the mic.Key Points From This Episode:Intense focus and interests. [00:05:29] Passion or discipline? [00:09:49] Importance of in-person connections. [00:14:09] Positive reframing of failures. [00:24:35] Shedding light on oneself. [00:32:11] Key Performance Indicators in Health. [00:35:15] Expectations and happiness equation. [00:44:32] Podcasting as a connection tool. [00:55:07] In-person connections and rapport. [01:02:03] Breathwork and personal experiences. [01:10:42] Looking to discover your science and optimize your life?APPLY FOR HEALTH OPTIMIZATION COACHINGhttps://calendly.com/andrespreschel/intro-call-with-andresLinks Mentioned in Today’s Episode:Click HERE to save on BiOptimizers MagnesiumPeopleMichael DonovanWebsiteJoe RoganWebsiteSpotify PodcastInstagramDr. Joel KahnOfficial WebsitePeter AttiaOfficial WebsiteBen GreenfieldOfficial WebsiteStacy SimsOfficial WebsiteBooks and References"Atomic Habits" by James ClearAmazon Link"The Almanack of Naval Ravikant" by Eric JorgensonAmazon Link"Die with Zero" by Bill PerkinsAmazon Link"The Body Keeps the Score" by Bessel van der Kolk (mentioned indirectly in context with mental and physical health)Amazon LinkSupport the show

Send us a textIn this fascinating episode, I sit down with Victor Sagalovsky, co-founder and CEO of Lightwater Scientific, a trailblazer in the world of deuterium depletion and its transformative impact on human health. Victor’s passion for understanding the quantum biology of water has led him to pioneer a revolutionary approach to longevity, energy optimization, and overall vitality through deuterium-depleted water. During our conversation, Victor dives into the science behind deuterium depletion and how it enhances mitochondrial function, oxygen utilization, and even helps to slow the aging process. He shares insights into the intricate relationship between water, energy production at the cellular level, and how managing deuterium levels can unlock profound benefits for performance, recovery, and longevity. This episode is a must-listen for anyone curious about the cutting-edge intersection of water science, quantum biology, and longevity. Whether you’re a biohacker, health enthusiast, or just seeking to elevate your wellness journey, Victor's expertise offers a unique and powerful perspective on how to use deuterium-depleted water as a tool for optimized health and performance. Tune in to discover how to take your health to the next level with insights that are both deeply scientific and highly actionable.Key Points From This Episode:00:04:24 - Introduction to Victor and Lightwater Scientific00:05:10 - Understanding Deuterium Depleted Water (DDW)00:06:42 - The Science Behind Energy Production00:12:33 - The Impact of Deuterium on Aging00:22:02 - The Process of Creating DDW00:35:36 - Caloric Restriction and Deuterium00:49:10 - Future Possibilities with Deuterium Management01:00:24 - Discovering the Self Through Water01:22:03  - Understanding Water's Role in Mineralization01:36:01 - Setting a Baseline for Deuterium Levels!Looking to discover your science and optimize your life?APPLY FOR HEALTH OPTIMIZATION COACHINGhttps://calendly.com/andrespreschel/intro-call-with-andresLinks Mentioned in Today’s Episode:Click HERE to save on BiOptimizers MagnesiumSpecial Offer:Get 10% off your first order with the discount code: PHYSIO.Also receive 20% off your Deuterium Tests.PeopleVictor SagalovskyLinkedIn ProfileDr. Laszlo BorosOfficial WebsiteDr. Gerald PollackOfficial WebsiteDr. Jack KruseOfficial WebsitePlacesLightwater ScientificOfficial WebsiteWater SymposiumWater Symposium Official WebsiteBooks and References"The Fourth Phase of Water" by Dr. Gerald PollackBook on AmazonDeuterium Test KitDeuterium Test WebsiteSupport the show

Send us a textIn this insightful episode, I'm honored to sit down with Dr. Joel Kahn, a world-renowned holistic cardiologist and a leading voice in the plant-based movement. With over 40 years of experience in cardiovascular medicine, Dr. Kahn has dedicated his career to preventing and reversing heart disease through lifestyle and nutrition. His expertise not only spans the intricacies of cardiovascular health but also encompasses the broader implications of adopting a plant-based diet for overall well-being. Dr. Kahn shares his personal journey toward embracing a whole food, plant-based diet, along with compelling insights from his clinical practice. His deep understanding of the relationship between lifestyle choices and health outcomes offers invaluable guidance for anyone looking to take charge of their well-being.Dr. Kahn provides actionable advice on how to optimize your diet, manage genetic predispositions, and integrate holistic practices into your daily life. Whether you're a healthcare professional, a wellness enthusiast, or someone curious about the benefits of a plant-based lifestyle, this discussion offers a wealth of knowledge and inspiration to help you thrive. Tune in to discover how you can beat heart disease, enhance your quality of life, and achieve lasting health.Key Points From This Episode:Holistic approach to medicine. [00:06:11]Top three KPIs for health. [00:10:25]Genetic contribution to heart disease. [00:12:49]Ancestral diets and caveman predecessors. [00:16:02]Subjective feelings versus objective health. [00:22:51]Plant-based diets reversing diabetes. [00:26:38]Nutrition in Medical Practice. [00:28:52]Plant-based diet nutrient needs. [00:32:53]Plant-based diet with salmon. [00:37:17]Plant-based diet and heavy metals. [00:41:30]Genetic Influence on Cholesterol Response. [00:44:25]Lipoprotein. [00:49:15]Plant-based diets and health. [00:52:08] Looking to discover your science and optimize your life?APPLY FOR HEALTH OPTIMIZATION COACHINGhttps://calendly.com/andrespreschel/intro-call-with-andresLinks Mentioned in Today’s Episode:Click HERE to save on BiOptimizers MagnesiumPeopleDr. Joel KahnOfficial WebsiteInstagramTwitterDean Ornish, MDOfficial WebsiteDr. Caldwell EsselstynOfficial WebsiteDr. Neil BarnardWikipediaDr. Walter LongoOfficial WebsiteBooks and ReferencesDiet for a New America by John RobbinsAmazon LinkThe Lancet (Medical Journal)Official WebsitePREDIMED StudyResearch ArticleCORDIOPREV StudyResearch ArticleSupport the show

Send us a textIn this compelling episode, I am honored to welcome Dr. Peter McCullough, a distinguished internist, cardiologist, and epidemiologist renowned for his outspoken views on COVID-19 and vaccine safety. Dr. McCullough, with his extensive background in medicine and public health, has been at the forefront of the pandemic response, offering critical insights and alternative perspectives on treatment protocols and vaccine efficacy. His vast experience and unfiltered commentary provide a unique and thought-provoking discussion on the current state of healthcare and future challenges.Our conversation delves into Dr. McCullough's profound journey through the pandemic, exploring his early advocacy for outpatient treatment protocols and the development of the widely known McCullough Protocol. He discusses the evolving landscape of COVID-19, from initial outbreak responses to current vaccine debates, shedding light on the complexities and controversies surrounding vaccine safety and public health policies. Dr. McCullough's candid reflections and data-driven analysis offer listeners a comprehensive understanding of the multifaceted issues at play.This episode is essential listening for anyone seeking to navigate the intricate web of pandemic information, vaccine considerations, and future health threats. Dr. McCullough shares invaluable insights on maintaining heart health, understanding the risks associated with vaccines, and preparing for potential future pandemics. Whether you're a healthcare professional, a concerned citizen, or simply looking to stay informed, Dr. McCullough's expertise and forthright approach provide a refreshing and empowering perspective on today's most pressing health issues. Tune in to gain a deeper understanding and to equip yourself with knowledge for a healthier future.Key Points From This Episode:Rise of propaganda. [00:08:15] Over-the-counter COVID treatment. [00:21:19] Carbohydrate strategies for athletes. [00:30:38] Ketones and calorie comparison. [00:34:04] Fasting throughout history and religions. [00:45:40] Myocarditis can be fatal. [01:02:26] Safety concerns of taking vaccines. [01:08:07] Conflict of interest in mandates. [01:13:35] Vaccine safety concerns. [01:17:44] Potential Long-Term Health Risks [01:19:11] Natural detoxification products. [01:27:49] Synergistic lifestyle considerations. [01:31:13] Bird flu preparations. [01:39:50] Censorship and propaganda in media. [01:44:30] Looking to discover your science and optimize your life?APPLY FOR HEALTH OPTIMIZATION COACHINGhttps://calendly.com/andrespreschel/intro-call-with-andresLinks Mentioned in Today’s Episode:Click HERE to save on BiOptimizers MagnesiumPeopleDr. Peter A. McCulloughLinkedIn ProfileTwitterDr. Boz (Annette Bosworth)Official WebsiteYouTube ChannelJoel KahnOfficial WebsiteDr. Justin MarchegianiOfficial WebsiteBooks and ReferencesCourage to FaceAmazon LinkSupport the show

Send us a textIn this compelling episode, I am honored to welcome Adam Wenguer, a passionate advocate for natural health solutions and a visionary in the world of cannabis-derived products. As the CEO at Element Health, Adam brings his extensive knowledge and personal experiences to light, advocating for the powerful benefits of CBD and hemp. His dedication is not just to advance personal wellness but also to redefine how we engage with nature and tackle the challenges of modern living.Throughout our conversation, Adam explores the intricate balance of the endocannabinoid system and its profound impact on everything from anxiety to physical recovery. He discusses how his personal journey and professional endeavors intersect, leading to groundbreaking insights into how CBD can enhance daily life, promote better sleep, and support mental clarity. His stories from the trenches of entrepreneurship and personal health advocacy illuminate the vast potential of integrating CBD into a holistic wellness regime.This episode is essential listening for anyone interested in natural remedies, personal resilience, and environmental stewardship. Adam’s narrative is a powerful reminder of the importance of reconnecting with nature, challenging conventional comfort, and the transformative potential of embracing plant-based health aids. Tune in to discover how Adam’s experiences and innovations in CBD can inspire a more balanced, health-focused approach to your daily lifeKey Points From This Episode:All things CBD. [00:04:13]CBD and Cannabis Legalization. [00:08:34]The power of CBD. [00:14:37]The endocannabinol system. [00:18:29]Endocannabinoid Deficiency Study. [00:20:24]Endocannabinoids for the runner's high. [00:23:27]Technology and physiology gap. [00:29:39]The diurnal effect of the endocannabinoid system. [00:32:43]CBD for anxiety relief. [00:35:24]CBD vs. THC Sleep Effects. [00:41:17]Overcoming marijuana dependency. [00:44:43]Challenging convenience in modern life. [00:48:29]Getting back to nature. [00:50:26]Embracing discomfort for growth. [00:56:14]CBD for public speaking anxiety. [00:59:29]Getting uncomfortable for growth. [01:03:08]Young minds in biohacking industry. [01:06:41]Looking to discover your science and optimize your life?APPLY FOR HEALTH OPTIMIZATION COACHINGhttps://calendly.com/andrespreschel/intro-call-with-andresLinks Mentioned in Today’s Episode:Click HERE to save on BiOptimizers MagnesiumPeopleAdam WenguerInstagramElement HealthBen GreenfieldOfficial WebsiteInstagramTwitterSupport the show