STEM-Talk

Harvard professor Charles Serhan discusses specialized pro-resolving mediators to resolve inflammation, shifting our understanding. Topics include his transition from a musician to a scientist, the potential of SPMs in healing, and their applications in various diseases.

Dave Feldman, founder of the Citizen Science Foundation, shares insights on cholesterol and the ketogenic diet. He discusses his journey, LDL cholesterol spike, and creation of Cholesterol Code. Topics include research collaboration, challenges in funding, and impact of carbohydrates on cholesterol levels.

Dr. Alessio Fasano, expert in celiac disease and gluten disorders, discusses gluten sensitivity affecting 20 million Americans. He shares insights on microbiome, intestinal permeability, and autoimmune disorders. Alessio talks about a new project studying infants at risk of celiac, published books 'Gluten Freedom' and 'Gut Feelings', and collaborative international research efforts. Additionally, he explores genetic aspects of celiac, complexities of microbiome research, gut permeability biomarkers, and the influence of genes, environment, and microbiome on autoimmune diseases.

Nicholas Norwitz, a Harvard Medical School student, discusses his journey overcoming diseases with a ketogenic diet. He delves into the effects of carbs vs. statins on cholesterol levels, lean mass hyper-responders, and the impact of a ketogenic diet on metabolic health.

Dr. Vyvyane Loh discusses atherosclerotic heart disease, focusing on variability in response to statins, the gap between medical practices and scientific advancements, and the connection between atherosclerosis and autoimmunity. She also explores therapeutic developments targeting inflammation and the significance of glyco-calics in disease development.

Dr. Johnathan Edwards discusses using ketamine to treat depression and prevent suicide, highlighting the alarming rise in suicide rates among youth. The podcast explores the benefits and risks of ketamine, its evolution in mental health treatment, and its unique neuroplastic effects. Additionally, it delves into the success of ketamine therapy in chronic pain management and its potential for suicide prevention, emphasizing the need for further research and support for these therapies.

Dr. Michael Leon discusses his research on olfaction enrichment to influence memory function and brain health, with applications for autism, anorexia, and dementia. The podcast explores the impact of rotating odors on dementia symptoms and memory enhancement, as well as the potential benefits of olfactory stimulation on cognitive function and neurological conditions. It also touches on study limitations and future plans for Alzheimer's treatment, highlighting the power of olfactory stimulation in improving memory, mood, and sleep quality.

Neuroscientist Mark Mattson discusses the pivotal role of glutamate in the brain, influencing cognitive functions and neurological disorders. He explains how glutamate controls learning, memory, creativity, and its involvement in disorders like autism and Alzheimer's. The discussion sheds light on the importance of understanding this neurotransmitter for brain health and function.

Dr. Marc Hamilton, an expert in muscle physiology, discusses the soleus push-up, a method to elevate metabolism while sitting. His research focuses on solving metabolic problems, optimizing fat metabolism, and improving glucose tolerance. He also highlights the health hazards of excessive sitting. The podcast covers topics such as the role of skeletal muscle in metabolism, the properties of the soleus muscle, and the benefits of soleus push-ups for sustaining oxidative metabolism.

Dr. Sten Stray-Gundersen discusses the benefits of blood-flow restriction training, including increased muscle strength, improved endurance, and reduced risk of injury. He also shares his research on hypoxia and endothelial function. The podcast covers Sten's upbringing, his success in sports, and his experience working in the field of exercise physiology. Additionally, it explores the contrasting approaches to blood-flow restriction training for elite athletes and middle-aged/older adults, as well as the effects of this training on cardiovascular responses.