Mind & Matter

Nick Jikomes
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Aug 28, 2023 • 2h 4min

Evolution of Human Behavior, Anatomy & Diet, Homo naledi & the Cave of Bones | John Hawks | 126

Send us a textDr. John Hawks is a paleoanthropologist and professor of anthropology at the University of Wisconsin-Madison. They discuss: the evolution of human behavior, diet, anatomy, and culture; Neanderthals, Denisovans, Homo erectus, and other species; the latest discoveries related to Homo naledi, which was the subject of the Netflix documentary, "Cave of Bones."To learn more about evolution, check out these episodes.*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app. AquaTru: Reverse osmosis water filters. Remove metals, microbes, endocrine disruptors and toxins from drinking water. $100 off AquaTru filters through link. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts
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Aug 21, 2023 • 1h 42min

Anxiety, Obsessive Compulsive Disorder, Microglia, From Being a WWII Orphan to the Nobel Prize | Mario Capecchi | 125

Dr. Mario Capecchi, Nobel laureate and genetics professor, discusses studying microglia in anxiety & OCD, his Nobel Prize-winning work, childhood experiences as a WWII orphan in Italy, immigrating to the US, exercise & diet, and advice for aspiring scientists.
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Aug 15, 2023 • 1h 29min

Hormonal Contraception, Sex Hormones, Menstruation, Pregnancy, Puberty, Estrogens, Androgens, Effects of Birth Control on Cognition | Adriene Beltz | 124

Send us a textDr. Adriene Beltz is an associated professor of psychology at the University of Michigan who studies the effects of sex hormones & hormonal contraception on human cognition and the brain. They discuss: sex hormones (androgens & estrogens); hormonal regulation of menstruation, puberty, and pregnancy; common forms of hormonal birth control & how they work; effects of sex hormones & hormonal birth control on cognition & the brain; and more.*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app. AquaTru: Reverse osmosis water filters. Remove metals, microbes, endocrine disruptors and toxins from drinking water. $100 off AquaTru filters through link. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts
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Aug 10, 2023 • 1h 30min

Endocannabinoids, Stress, Exercise, Cortisol, Anxiety, Cannabis & Effects of Marijuana on Brain Development | Matthew Hill | 123

Dr. Matthew Hill, a neuroscientist at the University of Calgary, dives into the fascinating world of the endocannabinoid system. He discusses how these cannabinoids regulate stress and anxiety and the surprising connections between exercise and endocannabinoids. Hill also explores the impact of THC on brain development and the significant differences in cannabis responses between genders. The episode further unveils the delicate balance of benefits and risks associated with THC exposure during pregnancy, offering thought-provoking insights on mental health and physical well-being.
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Aug 2, 2023 • 1h 16min

Cellular Aging, Taurine, Nutrition, Senescence, Longevity, Mitochondria, Metabolism | Vijay Yadav | 122

Send us a textNick talks to molecular physiologist Dr. Vijay Yadav, an assistant professor at Columbia University whose lab studies the molecular & cell biology of aging, nutrition, and longevity. They discuss: the cell biology of aging; how nutrients affect aging & disease; the atypical amino acid taurine & its effects on aging; taurine clinical trials & supplementation; diet, nutrition & anti-aging effects; and more.*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app. AquaTru: Reverse osmosis water filters. Remove metals, microbes, endocrine disruptors and toxins from drinking water. $100 off AquaTru filters through link. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts
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64 snips
Jul 19, 2023 • 1h 43min

Psychedelics, Metaplasticity, Critical Periods, Social Learning, Psilocybin, LSD, MDMA, Ketamine, Ibogaine & Neuroscience | Gül Dölen | 121

In a captivating discussion, Gül Dölen, a pioneering neuroscientist from Johns Hopkins University, delves into the fascinating world of psychedelics and their impact on mental health. She explains how substances like LSD and psilocybin open critical periods in brain development, enhancing social learning and plasticity. Gül contrasts these non-addictive drugs with traditional addictions, emphasizing their potential for therapeutic applications. The conversation also highlights the evolving landscape of psychiatry and the need for context in psychedelic treatments.
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Jul 11, 2023 • 1h 7min

Psychedelics, Depression, Psychotherapy, SSRIs, Human Clinical Experience of Psychedelic Medicine | Alan Davis | 120

Send us a textNick talks to Dr. Alan Davis, a clinical psychologist and Director of the Center for Psychedelic Drug Research & Education at Ohio State University. They discuss: the effectiveness of mainstream forms of psychotherapy and antidepressant medications (SSRIs) for depression; psychedelic medicine & psilocybin-assisted psychotherapy; the relevance of the subjective effects of psychedelics for their therapeutic effects; FDA approval for MDMA- and psilocybin-assisted psychotherapy in the coming years; and more.*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app. AquaTru: Reverse osmosis water filters. Remove metals, microbes, endocrine disruptors and toxins from drinking water. $100 off AquaTru filters through link. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts
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Jul 6, 2023 • 1h 17min

Psychedelics, Neuroplasticity, LSD, Psilocybin, Ketamine, MDMA, Latest Psychedelic Science | Bryan Roth | 119

Send us a textNick talks to Bryan Roth, MD, PhD, a Professor of Pharmacology at the University of North Carolina. Dr. Roth has been studying the molecular mechanisms of psychedelics since the 1980s. They discuss: serotonin 2A receptors in the mammalian brain; psychedelics & neuroplasticity; classic psychedelics (e.g. LSD, psilocybin, DMT) compared to drugs like ketamine & MDMA; TrkB receptors & BDNF; engineering novel drugs & psychiatric treatment methods; latest findings in psychedelic science.More psychedelic science content.*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app. AquaTru: Reverse osmosis water filters. Remove metals, microbes, endocrine disruptors and toxins from drinking water. $100 off AquaTru filters through link. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts
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5 snips
Jun 28, 2023 • 1h 1min

Psychedelics, Terence McKenna, Magic Mushrooms, DMT, Carl Jung, Culture | Dennis McKenna | 118

Send us a textNick talks to ethnopharmacologist Dr. Dennis McKenna, who is the brother of psychonaut Terence McKenna and author of the book, "The Brotherhood of the Screaming Abyss." They discuss: the lives and psychedelic adventures of Dennis & Terence McKenna; experiences with psilocybin mushrooms & DMT; Carl Jung & psychology; the medical relevance of subjective psychedelic experiences; drugs, culture & society; and more.*Not medical adviceSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app. AquaTru: Reverse osmosis water filters. Remove metals, microbes, endocrine disruptors and toxins from drinking water. $100 off AquaTru filters through link. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts
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Jun 9, 2023 • 1h 37min

Psychiatry, Psychedelic Medicine, LSD for Anxiety, MDMA for Autism, Medical Education, Patient Access & Mental Health | Daniel Karlin | 117

Send us a textNick talks to Daniel Karlin, MD, a board-certified physician in psychiatry, addiction medicine & clinical informatics who is the Chief Medical Officer at MindMed. They discuss: psychiatry; incentives in scientific & medical research; healthcare & mental health; psychedelics; LSD for anxiety; MDMA for autism; ibogaine derivatives for addiction; patient access & care; and more.*This content is never meant to serve as medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app. AquaTru: Reverse osmosis water filters. Remove metals, microbes, endocrine disruptors and toxins from drinking water. $100 off AquaTru filters through link. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

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