
MeSsy with Christina Applegate & Jamie Lynn Sigler
On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.
Latest episodes

14 snips
Apr 1, 2025 • 1h 24min
Mel Robbins
In this lively conversation, Mel Robbins, a bestselling author and renowned motivational speaker, joins the hosts to tackle overcoming obstacles and embracing acceptance. They dive into the 'let them' theory, advocating for personal agency in challenging circumstances. Mel shares her insights on resilience while navigating chronic illness, emphasizing the importance of support, self-talk, and gratitude. The discussion is peppered with personal anecdotes, practical tools, and a spirited reflection on reclaiming joy amidst adversity.

Mar 25, 2025 • 1h 10min
Andy Cohen
This week, Christina and Jamie are joined by Andy Cohen. They indulge in their Bravo obsession and discuss why reality TV helps when you’re going through something, Andy’s career trajectory, parenting, and more.Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison BresnickAudio Engineer: Josh WindischGet 20% off Shop By Bravo from 3/25 – 4/25 with code MESSY20.https://shopbybravo.com/?utm_source=instagram.com&utm_medium=social&utm_campaign=messypod&utm_term=&utm_content=homepageThis episode is sponsored by:Purity Woods - Purity Woods has a special coupon code specifically for our listeners, so you can try it for yourself for 27% off today. Just go to puritywoods.com/MESSY or enter MESSY at checkout. Honeylove - Get 20% OFF @honeylove by going to honeylove.com/MESSY! #honeylovepodGreenchef - Thrive all year with clean, easy meals from Green Chef. Go to GreenChef.com/messyfree and use code messyfree to get started with FREE Salads for two months plus 50% off your first box. GreenChef The #1 Meal Kit for Eating Well.Function - Function currently has a waitlist, but they are offering my audience the chance to skip it!Head to functionhealth.com/MESSY or enter code MESSY when signing up to skip the waitlist!” Lume - Control Body Odor ANYWHERE with @lumedeodorant and get 15% off with promo code MESS at LumeDeodorant.com! #lumepod

Mar 18, 2025 • 1h 4min
One Year of MeSsy
This week, on the one year anniversary of MeSsy’s launch, Christina and Jamie read listener emails. They also discuss going where the love is, paying attention to what’s happening in your body, and much more.Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison BresnickAudio Engineer: Josh WindischThis episode is sponsored by:Fabric - Join the thousands of parents who trust Fabric to help protect their family. Apply today in just minutes at meetfabric.com/messy Policies issued by Western-Southern Life Assurance Company. Not available in certain states. Prices subject to underwriting and health questions.Zoc Doc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a top-rated doctor today. One Skin - Get 15% off OneSkin with the code Messy at https://www.oneskin.co/ #oneskinpodBranch Basics - Get 15% off Branch Basics with the code Messy at https://branchbasics.com/messy #branchbasicspodPurity Woods - Purity Woods has a special coupon code specifically for our listeners, so you can try it for yourself for 27% off today. Just go to puritywoods.com/MESSY or enter MESSY at checkout.

Mar 11, 2025 • 1h 22min
Katey Sagal
This week, Christina and Jamie are joined by Katey Sagal. They share their perspectives from “Married... with Children,” and discuss walking through fear, living life one day at a time, shame, and more.Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison BresnickAudio Engineer: Josh WindischShop MeSsy Merch: https://messypodcastmerch.giveswagger.com/messy_podcast_merch/shop/home This episode is sponsored by:Honeylove - Get 20% OFF @honeylove by going to honeylove.com/MESSY! #honeylovepodBetterHelp - This episode is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.”Sleep Number - Why choose a Sleep Number smart bed? So you can choose your ideal comfort on either side. The only bed that lets you make each side firmer or softer, whenever you like – your Sleep Number setting. Sleep Number smart beds start at $999. Exclusively at a Sleep Number® store near you. See store or sleepnumber.com for details.Public Rec - Upgrade your wardrobe instantly and save 20% off with the code MS at https://www.publicrec.com/ms #publicrecpodMudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at mudwtr.com/MESSY! #mudwtrpodFatty15 - Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/MESSY and using code MESSY at checkout.

Mar 4, 2025 • 1h 4min
Heels and Hats
This week, Christina and Jamie read listener emails and discuss giving yourself a little push, finding ways to enjoy life, setting achievable goals, and more.Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison BresnickAudio Engineer: Josh WindischThis episode is sponsored by:Function: - Function currently has a waitlist, but they are offering my audience the chance to skip it! Head to functionhealth.com/MESSY or enter code MESSY when signing up to skip the waitlist!” BetterHelp - This episode is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.”Sleep Number - Why choose a Sleep Number smart bed? So you can choose your ideal comfort on either side. The only bed that lets you make each side firmer or softer, whenever you like – your Sleep Number setting. Sleep Number smart beds start at $999. Exclusively at a Sleep Number® store near you. See store or sleepnumber.com for details.Lume - Control Body Odor ANYWHERE with @lumedeodorant and get 15% off with promo code MESS at LumeDeodorant.com! #lumepodiRestore - Unlock your best skin with @iRestorelaser and save $205 off your iRestore Illumina Face Mask with code Messy25 at irestorelaser.com/messy25 #irestorepodAG1 - AG1 is offering new subscribers a FREE $76 gift when you sign up. You’ll get a Welcome Kit, a bottle of D3K2 AND 5 free travel packs in your first box. So make sure to check out DrinkAG1.com/messy to get this offer!

Feb 25, 2025 • 1h 11min
How to Make Your Own Community with Allie Signorelli
This week, Christina and Jamie are joined by Allie Signorelli, a Young Onset Parkinson’s patient and advocate. They discuss her journey to getting diagnosed, the importance of being honest, paying attention to symptoms, finding gratitude, and more.Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison BresnickAudio Engineer: Josh WindischThis show is sponsored by:Mudwtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at mudwtr.com/messy #mudwtrpodCalm - Stress less, sleep more, and live better with Calm. For listeners of our show, Calm is offering an exclusive offer of 40% off a Calm Premium Subscription at calm.com/MESSY for 40% off unlimited access to Calm’s entire library. Purity Woods - The good people at Purity Woods have a special coupon code specifically for our listeners, so you can try it for yourself for 27% off today. Just go to puritywoods.com/MESSY or enter MESSY at checkout. Function - Function currently has a waitlist, but they are offering my audience the chance to skip it!Head to functionhealth.com/MESSY or enter code MESSY when signing up to skip the waitlist!” Sleep Number - Why choose a Sleep Number smart bed? So you can choose your ideal comfort on either side. The only bed that lets you make each side firmer or softer, whenever you like – your Sleep Number setting. Sleep Number smart beds start at $999. Exclusively at a Sleep Number® store near you. See store or sleepnumber.com for details.

Feb 18, 2025 • 1h 11min
Reimagining Your Dreams with Chad King
This week, Christina and Jamie are joined by musician Chad King. They discuss his diagnosis, the burden of living in a state of flight or fight, A Great Big World’s new music, how to reimagine your dreams, and much more.Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison BresnickAudio Engineer: Josh WindischThis show is sponsored by:AG1 - AG1 is offering new subscribers a FREE $76 gift when you sign up. You’ll get a Welcome Kit, a bottle of D3K2 AND 5 free travel packs in your first box. So make sure to check out DrinkAG1.com/messy to get this offer! Fabric - Join the thousands of parents who trust Fabric to help protect their family. Apply today in just minutes at meetfabric.com/messy Policies issued by Western-Southern Life Assurance Company. Not available in certain states. Prices subject to underwriting and health questions.Zoc Doc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a top-rated doctor today. Purity Woods - The good people at Purity Woods have a special coupon codespecifically for my listeners, so you can try it for yourself for 27% off today. Just go to puritywoods.com/MESSY or enter MESSY at checkout. Sleep Number - Save 50% on the NEW Sleep Number Limited Edition smart bed for a limited time. Exclusively at a Sleep Number® store near you. See store or sleepnumber.com for details.Everyday Dose - Head over to everydaydose.com/messy for 25% off plus 5 free gifts with your first order.

Feb 11, 2025 • 1h 11min
I Don’t Want to Feel Like I’m Broken Anymore
This week, Christina and Jamie read listener emails and discuss mobility aids, going out of your comfort zone, the impact of stress, and more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison BresnickAudio Engineer: Josh WindischTo answer the question in the episode, go to messythepodcast.comThis episode is sponsored by:BetterHelp - Discover your relationship green flags, with Betterhelp. Visit BetterHelp.com/messy to get 10% off your first month.Everyday Dose - Head over to everydaydose.com/messy for 25% off plus 5 free gifts with your first order:Fatty15 - Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/MESSY and using code MESSY at checkout.Function - Try Function and skip the waitlist using our link https://www.functionhealth.com/messyHoneylove - Start the new year off right with Honeylove. Get 20% OFF by going to honeylove.com/messy! #honeylovepodSleep Number. Save 50% on the NEW Sleep Number Limited Edition smart bed for a limited time. Exclusively at a Sleep Number® store near you. See store or sleepnumber.com for details.

19 snips
Feb 4, 2025 • 1h 30min
How to Feel Safe in Your Body with Deb Dana
Deb Dana, a clinician and expert in polyvagal theory, shares her insights on trauma and the nervous system. She discusses how early experiences shape our emotional responses and the importance of feeling safe in our bodies. The conversation dives into the healing potential of self-awareness and connection, while navigating chronic illness and trauma. Deb also emphasizes recognizing emotional states and utilizing coping mechanisms, as well as the value of community support in fostering resilience and emotional well-being.

Jan 28, 2025 • 1h 5min
Christian Siriano
This week, Christina and Jamie are joined by fashion designer Christian Siriano. They discuss how he came to work with Christina, inclusivity in fashion, taking risks, and more.Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison BresnickAudio Engineer: Josh WindischThis show is sponsored by: - Public Rec -Upgrade your wardrobe instantly and save 20% off with the code mess at https://www.publicrec.com/mess #publicrecpodSleep Number - Right now you can save 50% on the NEW Sleep Number Limited Edition smart bed for a limited time. Exclusively at a Sleep Number® store near you. See store or sleepnumber.com for detailsEveryday Dose - Head over to everydaydose.com/messy for 25% off plus 5 free gifts with your first order:Calm - Stress less, sleep more, and live better with Calm. For listeners of our show, Calm is offering an exclusive offer of 40% off a Calm Premium Subscription at calm.com/MESSY. Purity Woods - The good people at Purity Woods have a special coupon codespecifically for my listeners, so you can try it for yourself for 27% off today. Just go to puritywoods.com/MESSY or enter MESSY at checkout.